CN1314398C - 皮肤病乳膏及制备方法 - Google Patents
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Abstract
皮肤病乳膏是一种治疗皮肤病的药物，它克服了其它治疗皮肤病药物及方法存在的问题，它是由硝酸咪康唑200g、克霉唑0.1g、维A酸0.01g、维生素A胶丸100单位、维生素B1 0.02g、维生素B6 0.02g，硬脂酸1.5g、液体石蜡2.5g、三乙醇胺0.4g、甘油1g、尼泊金乙酯0.01g、硼砂0.01g、蒸馏水4.6g根据一定工艺制成的；皮肤病乳膏是一种新剂型、新配方乳膏，它具有作用快、穿透力强、生效迅速、治疗时间短等特点。
Description
一、技术领域：本发明涉及一种治疗皮肤病的药物，尤其是皮肤病乳膏及制备方法。
二、背景技术：目前，皮肤病发病率高、种类繁多、因其多发生于体表，不仅使患者遭受疾病本身的痛苦，而且有碍外观和容貌，给患者带来了很大的烦恼。近年来随着人民生活水平的不断提高，对皮肤病的求治与日具增，随之治疗皮肤病的各种软膏、乳膏市场上品种繁多，如西安杨森的达克宁、军事医学研究所研究的孚琪乳膏、中国深圳三九药业股份有限公司生产的三九皮炎平乳膏，这些药物都是我们国家在临床皮肤病治疗当中的名牌和首选药物。在皮肤病的临床治疗中：(1)达克宁只限于真菌感染，如脚癣、股癣、手癣、体癣、花斑癣、头癣、甲癣，治疗时间长(2至5周)、甲癣7个月左右才能见到疗效。而且局部涂擦有油腻感。(2)孚琪乳膏也只限于真菌感染。如体癣、股癣、花斑癣等，临床验证治疗时间长(2至4周)局部因药刺激反应明显。(3)三九皮炎平软膏仅用于湿疹、皮炎、皮肤瘙痒症，以上三种药物在临床治疗中都有局限性，皮肤病在人群中发病率高。在一个人体上可以有多种皮肤病同时存在，治疗中有一定的困难，几种软膏需同时应用，也给病人带来不便。
三、发明内容：本发明的目的是提供皮肤病乳膏及制备方法，它克服了其它治疗皮肤病药物及方法存在的问题，本发明的目的是这样实现的，它是由硝酸咪康唑200g、克霉唑0.1g、维A酸0.01g、维生素A胶丸100单位、维生素B1 0.02g、维生素B6 0.02g，硬脂酸1.5g、液体石蜡2.5g、三乙醇胺0.4g、甘油1g、尼泊金乙酯0.01g、硼砂0.01g、蒸馏水4.6g制成的。
其制备方法为：先将硬脂酸1.5g、液体石蜡2.5g、三乙醇胺0.4g、甘油1g、尼泊金乙酯0.01g、硼砂0.01g、蒸馏水4.6g调和成基质，然后将硝酸咪康唑200g、克霉唑0.1g、维A酸0.01g、维生素A胶丸100单位、维生素B1 0.02g、维生素B6 0.02g一起加入基质内，在容器内调成乳膏，最后包装即可。
皮肤病乳膏是一种新剂型、新配方乳膏，它具有作用快、穿透力强、生效迅速、治疗时间短等特点。
治疗范围：1、脚癣、体癣、股癣、花斑癣、扁平苔癣、急慢性牛皮癣、神经性皮炎。2、各种类型的湿疹：婴幼儿面部湿疹、肛门湿疹、会阴部湿疹。3、接触性皮炎、药物性皮炎、日光性皮炎、脂溢性皮炎、荨麻疹、皮肤瘙痒症。(4)青春痘(面部痤疮)、酒渣鼻、蝴蝶斑、妊娠斑、黄褐斑。
治病方法：外用，每日2——3次，取少量药膏在患部均匀涂抹，直到全部吸收；急性(5——7天)、慢性(3——5周)，治愈率高，副作用小，对皮肤无刺激作用、老人、婴幼儿、孕妇均可使用，药物稳定，不污染衣物、易洗除；应用范围仅限于皮肤病的局部治疗。
治疗结果：1、脚癣、体癣、股癣、头癣、花斑癣有效率98％、治愈率93％；2、神经性皮炎、牛皮癣有效率92％；3、各种类型的湿疹有效率100％、治愈率98％；4、接触性皮炎、药物性皮炎、日光性皮炎、脂溢性皮炎有效率100％、治愈率96％；5、青春痘(面部痤疮)、酒渣鼻有效率93％、治愈率80％；6、蝴蝶斑、妊娠斑、黄褐斑有效率100％、治愈率90％。
四、具体实施方式：本发明是由硝酸咪康唑200g、克霉唑0.1g、维A酸0.01g、维生素A胶丸100单位、维生素B1 0.02g、维生素B60.02g，硬脂酸1.5g、液体石蜡2.5g、三乙醇胺0.4g、甘油1g、尼泊金乙酯0.01g、硼砂0.01g、蒸馏水4.6g制成的。
其制备方法为：先将硬脂酸1.5g、液体石蜡2.5g、三乙醇胺0.4g、甘油1g、尼泊金乙酯0.01g、硼砂0.01g、蒸馏水4.6g调和成基质，然后将硝酸咪康唑200g、克霉唑0.1g、维A酸0.01g、维生素A胶丸100单位、维生素B1 0.02g、维生素B6 0.02g一起加入基质内，在容器内调成乳膏，最后包装即可。
Claims (2)
1、皮肤病乳膏，其特征是：它由硝酸咪康唑200g、克霉唑0.1g、维A酸0.01g、维生素A胶丸100单位、维生素B10.02g、维生素B60.02g，硬脂酸1.5g、液体石蜡2.5g、三乙醇胺0.4g、甘油1g、尼泊金乙酯0.01g、硼砂0.01g、蒸馏水4.6g制成的。
2、根据权利要求1所述皮肤病乳膏的制备方法，其特征是：先将硬脂酸1.5g、液体石蜡2.5g、三乙醇胺0.4g、甘油1g、尼泊金乙酯0.01g、硼砂0.01g、蒸馏水4.6g调和成基质，然后将硝酸咪康唑200g、克霉唑0.1g、维A酸0.01g、维生素A胶丸100单位、维生素B10.02g、维生素B60.02g一起加入基质内，在容器内调成乳膏，最后包装即可。
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| CN 200510017557 CN1314398C (zh) | 2005-05-10 | 2005-05-10 | 皮肤病乳膏及制备方法 |
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| CN1314398C true CN1314398C (zh) | 2007-05-09 |
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| CN101618018B (zh) * | 2008-07-01 | 2011-11-09 | 上海通用药业股份有限公司 | 一种硝酸咪康唑微粒及其制备方法和药物组合物 |
| CN108042483A (zh) * | 2017-12-26 | 2018-05-18 | 重庆希尔安药业有限公司 | 硝酸咪康唑乳膏及其制备方法 |
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