CN1314390C - 具有多重包衣的药物剂型 - Google Patents

具有多重包衣的药物剂型 Download PDF

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Publication number
CN1314390C
CN1314390C CNB018238009A CN01823800A CN1314390C CN 1314390 C CN1314390 C CN 1314390C CN B018238009 A CNB018238009 A CN B018238009A CN 01823800 A CN01823800 A CN 01823800A CN 1314390 C CN1314390 C CN 1314390C
Authority
CN
China
Prior art keywords
coating layer
poly
methacrylic acid
methyl methacrylate
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB018238009A
Other languages
English (en)
Chinese (zh)
Other versions
CN1558754A (zh
Inventor
G·P·迪特马
J·M·阿曼特
T·R·克龙克
D·G·纽比
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32823137&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1314390(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of CN1558754A publication Critical patent/CN1558754A/zh
Application granted granted Critical
Publication of CN1314390C publication Critical patent/CN1314390C/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CNB018238009A 2001-11-23 2001-11-23 具有多重包衣的药物剂型 Expired - Lifetime CN1314390C (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2001/043893 WO2003045356A1 (en) 2000-11-20 2001-11-23 Pharmaceutical dosage form with multiple coatings

Publications (2)

Publication Number Publication Date
CN1558754A CN1558754A (zh) 2004-12-29
CN1314390C true CN1314390C (zh) 2007-05-09

Family

ID=32823137

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB018238009A Expired - Lifetime CN1314390C (zh) 2001-11-23 2001-11-23 具有多重包衣的药物剂型

Country Status (15)

Country Link
EP (1) EP1453487B2 (enExample)
JP (1) JP4999037B2 (enExample)
CN (1) CN1314390C (enExample)
AT (1) ATE389389T1 (enExample)
AU (1) AU2002226955B2 (enExample)
BR (1) BRPI0117180B8 (enExample)
DE (1) DE60133319T3 (enExample)
DK (1) DK1453487T3 (enExample)
ES (1) ES2301575T5 (enExample)
HU (1) HU231030B1 (enExample)
IL (1) IL161628A (enExample)
MX (1) MXPA04004747A (enExample)
NZ (1) NZ532564A (enExample)
PT (1) PT1453487E (enExample)
WO (1) WO2003045356A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105025888A (zh) * 2013-02-22 2015-11-04 志瑞亚新药工业株式会社 肠溶片

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8563522B2 (en) 1997-07-08 2013-10-22 The Iams Company Method of maintaining and/or attenuating a decline in quality of life
CA2359812C (en) 2000-11-20 2004-02-10 The Procter & Gamble Company Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
US8168170B2 (en) 2002-10-03 2012-05-01 The Procter And Gamble Company Compositions having an inner core and at least three surrounding layers
MXPA06000852A (es) * 2003-07-24 2006-03-30 Smithkline Beecham Corp Peliculas que se disuelven oralmente.
GB2407501A (en) * 2003-11-03 2005-05-04 Ist Superiore Sanita Nanoparticles for delivery of a pharmacologically active agent, comprising water insoluble (co)polymer core & hydrophilic acrylate-based (co)polymer shell
US7785635B1 (en) 2003-12-19 2010-08-31 The Procter & Gamble Company Methods of use of probiotic lactobacilli for companion animals
US8894991B2 (en) 2003-12-19 2014-11-25 The Iams Company Canine probiotic Lactobacilli
US20050152884A1 (en) 2003-12-19 2005-07-14 The Procter & Gamble Company Canine probiotic Bifidobacteria globosum
US20050158294A1 (en) 2003-12-19 2005-07-21 The Procter & Gamble Company Canine probiotic Bifidobacteria pseudolongum
US8877178B2 (en) 2003-12-19 2014-11-04 The Iams Company Methods of use of probiotic bifidobacteria for companion animals
JP2008511658A (ja) * 2004-09-01 2008-04-17 ザ プロクター アンド ギャンブル カンパニー ５−アミノ−２−ヒドロキシ安息香酸及び還元糖を含む組成物
EP2270131A1 (en) 2005-05-31 2011-01-05 The Iams Company Feline probiotic lactobacilli
PL1885383T3 (pl) 2005-05-31 2017-06-30 Iams Europe B.V. Kocie probiotyczne bifidobakterie
CN101711158A (zh) 2007-02-01 2010-05-19 爱默思公司 使用葡萄糖抗代谢物、鳄梨或鳄梨提取物减轻哺乳动物炎症和应激反应的方法
AU2007352872B2 (en) 2007-05-07 2013-03-14 Evonik Operations Gmbh Solid dosage forms comprising an enteric coating with accelerated drug release
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
GB201202433D0 (en) 2012-02-13 2012-03-28 Diurnal Ltd Controlled drug release
JP2012107058A (ja) * 2012-02-27 2012-06-07 Warner Chilcott Co Llc 複数のコーティングを有する医薬剤形
US20140141075A1 (en) * 2012-11-21 2014-05-22 Warner Chilcott Company, Llc 5-aminosalicylic acid capsule formulation
GB2510754B (en) * 2013-02-12 2016-07-13 Diurnal Ltd Controlled drug release
JP6165022B2 (ja) * 2013-10-30 2017-07-19 株式会社ファンケル 放出制御型ソフトカプセル剤
WO2016001843A1 (en) * 2014-06-30 2016-01-07 Sun Pharmaceutical Industries Limited Extended-release gastroretentive tablets of voglibose
EP3162362A1 (de) * 2015-10-30 2017-05-03 Dr. Falk Pharma Gmbh Optimierte mesalazinhaltige hochdosistablette
CN107661370A (zh) * 2017-11-20 2018-02-06 贵州浩诚药业有限公司 一种苦参片及其制备方法
JP2021528483A (ja) * 2018-05-03 2021-10-21 エムダブリュ エンキャップ リミテッド 下部胃腸管への医薬の送達のための剤形
EP3613414A1 (de) 2018-08-24 2020-02-26 Dr. Falk Pharma Gmbh Pellets mit mehrschichtiger struktur zur verzögerten freisetzung des wirkstoffs im distalen kolon
CN113993509A (zh) * 2019-05-15 2022-01-28 赢创运营有限公司 用胶囊填充机制备具有基于(甲基)丙烯酸酯共聚物的包衣的填充硬壳胶囊的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171580A (en) * 1988-10-20 1992-12-15 Boehringer Ingelheim Italia S.P.A. Orally-pharmaceutical preparations with colon selective delivery
CN1239425A (zh) * 1996-11-15 1999-12-22 普罗克特和甘保尔公司 供结肠释放的具有多层肠溶聚合物包衣的药剂

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
WO1998027967A1 (en) * 1996-12-20 1998-07-02 Dumex-Alpharma A/S Release-controlled coated tablets

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5171580A (en) * 1988-10-20 1992-12-15 Boehringer Ingelheim Italia S.P.A. Orally-pharmaceutical preparations with colon selective delivery
CN1239425A (zh) * 1996-11-15 1999-12-22 普罗克特和甘保尔公司 供结肠释放的具有多层肠溶聚合物包衣的药剂

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105025888A (zh) * 2013-02-22 2015-11-04 志瑞亚新药工业株式会社 肠溶片
CN105025888B (zh) * 2013-02-22 2018-10-12 志瑞亚新药工业株式会社 肠溶片

Also Published As

Publication number Publication date
BR0117180A (pt) 2004-11-03
PT1453487E (pt) 2008-05-13
EP1453487B1 (en) 2008-03-19
EP1453487A1 (en) 2004-09-08
EP1453487B2 (en) 2021-03-31
AU2002226955B2 (en) 2006-04-27
AU2002226955A1 (en) 2003-06-10
IL161628A0 (en) 2004-09-27
CN1558754A (zh) 2004-12-29
HU231030B1 (hu) 2019-12-30
ES2301575T3 (es) 2008-07-01
HUP0402230A2 (hu) 2005-02-28
MXPA04004747A (es) 2004-08-02
JP4999037B2 (ja) 2012-08-15
JP2005510539A (ja) 2005-04-21
BRPI0117180B8 (pt) 2021-05-25
WO2003045356A1 (en) 2003-06-05
DE60133319T2 (de) 2009-04-30
DK1453487T3 (da) 2008-07-21
NZ532564A (en) 2006-06-30
HUP0402230A3 (en) 2008-04-28
BRPI0117180B1 (pt) 2018-12-04
ES2301575T5 (es) 2022-04-22
ATE389389T1 (de) 2008-04-15
IL161628A (en) 2014-03-31
DE60133319T3 (de) 2021-08-05
DE60133319D1 (de) 2008-04-30

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Granted publication date: 20070509

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