CN1308015C - Chinese medicine for curing toothache - Google Patents

Abstract

The present invention relates to a Chinese medicine for treating toothache, which comprises the following components of the portions in the proportion by weight: 15 to 25 portions of rhizoma cimicifugae, 25 to 35 portions of gypsum, 10 to 20 portions of liquorice, 10 to 20 portions of cortex moutan, 15 to 25 portions of coptis, 15 to 25 portions of rhubarb, 10 to 20 portions of mint stem, 10 to 20 portions of asarum herb, 15 to 25 portions of kakuda figwort roots, and 10 to 20 portions of glabrousleaf pittosporum. The Chinese medicine of the present invention has good functions of sedation, analgesia, blood nourishment and ache alleviation, and can eliminate inflammation, detoxicate and broad-spectrum resist bacilli. Pungent warm, divergence and ache alleviation are performed on the upper energizer, cool is dispelled to the middle energizer, bitter cold is lowered to the lower energizer, the upper energizer, the middle energizer and the lower energizer are through adjusted, and fire is abreacted so that toothache can be cured. The present invention can be widely used for treating various tooth diseases.

Description

A kind of Chinese medicine for the treatment of toothache

Technical field: the present invention relates to Chinese medicine, particularly the sick Chinese medicine of treatment toothache.

Background technology: the sick Western medicine curative effect of treatment toothache at present is bad and side effect is generally all arranged, and the sick Shen pharmacopoeia class of treatment toothache is various, but curative effect is slow, the effect of curing the disease is very not remarkable.

The content of invention: overcome the deficiency that prior art exists, it is fast and can effect a radical cure the Chinese medicine of the various toothache that periodontitis, toothache, periodontal abscess, gingivitis, pulpitis etc. cause to propose a kind of curative effect.This Chinese medicine comprises following raw material: Rhizoma Cimicifugae, Gypsum Fibrosum, Radix Glycyrrhizae, unpeeled CORTEX MOUTAN, Rhizoma Coptidis, Radix Et Rhizoma Rhei, peppermint stem, Herba Asari, Radix Scrophulariae, Semen Pittospori Glabrati, the weight ratio umber of its each raw material is: Rhizoma Cimicifugae 15-25 part, Gypsum Fibrosum 25-35 part, Radix Glycyrrhizae 10--20 part, unpeeled CORTEX MOUTAN 10-20 part, Rhizoma Coptidis 15-25 part, Radix Et Rhizoma Rhei 15-25 part, peppermint stem 10-20 part, Herba Asari 10-20 part, Radix Scrophulariae 15-25 part, Semen Pittospori Glabrati 10--20 part.Its production method is: pulverizing after above-mentioned crude drug is mixed, sealing are finished medicines.Therefore Chinese medicine of the present invention have good calmness owing to contain peppermint stem, analgesic activity, the Radix Angelicae Sinensis analgesic effect of nourishing blood, owing to contain Semen Pittospori Glabrati, Rhizoma Coptidis, but Radix Et Rhizoma Rhei is the eliminating inflammation and expelling toxin broad-spectrum antiseptic therefore, unpeeled CORTEX MOUTAN can be antibiotic analgesic, analgesia, the strong compatibility of the scorching effect of a heatable brick bed can increase the power of antiinflammatory antipyretic-antalgic with Radix Scrophulariae, the Gypsum Fibrosum clearing stomach is analgesic kind descending, Rhizoma Cimicifugae is cool in nature and rise and to be good at, make and reach on the efficacy of a drug in tooth portion, the gentle detoxifcation of Radix Glycyrrhizae, concoct all medicines, Radix Glycyrrhizae has the effect of corticoid sample simultaneously, can separate various poison, and the alleviation gastrointestinal convulsion is arranged, can rise and to fall, with the medicine of a cold nature, the cathartic compatibility has the mediation property of medicine, the performance drug effect makes prescription of the present invention hot cool, Xin Wen disperses pain relieving in last, cold separate in, bitter cold is fallen in following, and the upper, middle and lower three warmers are logical to be transferred, fire goes out to have the road, thereby various odontopathy can heal.

The specific embodiment: get Rhizoma Cimicifugae 20g, Gypsum Fibrosum 30g, Radix Glycyrrhizae 15g, unpeeled CORTEX MOUTAN 15g, Rhizoma Coptidis 20g, Radix Et Rhizoma Rhei 20g, peppermint stem 15g, Herba Asari 15g, Radix Scrophulariae 20g, Semen Pittospori Glabrati 15g.Its production method is: pulverizing after above-mentioned ten crude drugs are mixed, sealing are finished medicines.

The usage of this medicine and consumption: 314 times on the oral one, each 10 grams; The last white pickling wine of external Nidus Vespae, the consumption of each Nidus Vespae is the 0.3-0.5 gram, is coated on the tooth of pain with a little, tells after 3-5 minute, Nidus Vespae has the effect of attacking of order wind counteracting toxic substances, reducing swelling and alleviating pain, takes back diet five sufferings, raw and cold greasy.

In order to estimate the clinical medicine safety of Chinese medicine of the present invention, it has been carried out toxicity test research, be reported as follows:

1. be subjected to test product: a kind of Chinese medicine every day for the treatment of toothache 4 times, each 10 grams.

2. experimental animal: the white mice of Kunming kind, body weight 18-22 gram, male and female dual-purpose.

3. the preparation of dosage and test drug: get a kind of Chinese medicine for the treatment of toothache 40 grams, put and add the 100.0ml distilled water in the mortar and be uniformly dispersed, making concentration is 24% solution.Administering mode is a gastric infusion

One, the mensuration of median lethal dose(LD 50)

Get 9 of mices, divide three groups, but fail to find out the dosage of 100% animal dead.Select 50 of the healthy mices of body weight 20 ± 2g for use, male and female half and half are divided into five groups at random, an oral administration gavage administration, and dosage is by geometric progression, and maximum dose level calculates with the maximum volume that can accept.Observed 7 days none death as a result after the administration.

Two, mtd test

Select 20 of healthy mices, male and female half and half, normally raise 1 after, administration is 4 times in 24 hours, 5 hours blanking times, total administration volume 120ml/kg observed 7 continuously, did not see untoward reaction and death condition, can think the oral avirulence of this medicine.

The maximum tolerated dose multiple is calculated as follows:

$=\frac{0.8\×4\×24\%}{20}\×\frac{60000}{6\×4\×0.4}$

Calculate if obey 40 grams every day by the adult, the result is 240 times of normal clinical dosage, illustrates that a kind of Chinese medicine for the treatment of toothache has safety.

A kind of Chinese medicine clinical summary for the treatment of toothache

One group to the statistics in the odontopathy clinical observation material.

This organizes 5% case for observing the patient of treatment.Man's 43 examples wherein, women 16 examples, age 40-50 year 10 examples, 51-60 year 30 examples, 19 examples more than 61 years old, with periodontitis 9 examples, gingivitis 6 examples, toothache, pulpitis 33 examples, dense swollen 3 examples of periodontal.Wherein Therapeutic Method is the patient to be divided into two groups at random, and 39 examples are organized in treatment, obeys capsule of the present invention, four times a day, and each 10 grams, 60 days is a course of treatment.Matched group 20 examples are taken other medicine, and 60 days is a course of treatment, withdraws other medicines before the administration, all do inspection before and after the treatment, and the result shows that the treatment group effective percentage of taking Chinese medicine of the present invention is 98%, and matched group does not have obvious effects.

Claims (1)

1, a kind of Chinese medicine for the treatment of toothache is characterized in that: be made up of following components by part by weight: Rhizoma Cimicifugae 15-25 part, Gypsum Fibrosum 25-35 part, Radix Glycyrrhizae 10-20 part, unpeeled CORTEX MOUTAN 10-20 part, Rhizoma Coptidis 15-25 part, Radix Et Rhizoma Rhei 15-25 part, peppermint stem 10-20 part, Herba Asari 10-20 part, Radix Scrophulariae 15-25 part, Semen Pittospori Glabrati 10-20 part.