CN1287857A - Traditional Chinese patented medicine for treating hepatitis and its prepn. method - Google Patents
Traditional Chinese patented medicine for treating hepatitis and its prepn. method Download PDFInfo
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- CN1287857A CN1287857A CN 99119384 CN99119384A CN1287857A CN 1287857 A CN1287857 A CN 1287857A CN 99119384 CN99119384 CN 99119384 CN 99119384 A CN99119384 A CN 99119384A CN 1287857 A CN1287857 A CN 1287857A
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Abstract
The present inventioin relates to traditional Chinese medicine for treating hepatitis. Based on cause of disease, pathological mechanism and pharmacodynamics, it selects fructus schisand rae, salvia root, astragalus root, radix isatidis, herba verbenae, herba artemisiae scopariae, ganoderma lucidum, subprostrate sophora, notoginseng, etc. and makes the pill preparation.
Description
What the present invention relates to is a kind of preparation method for the treatment of hepatitis disease Chinese formulated products.
Liver cirrhosis is the chronic progressive disease of liver, and concurrent ascites when serious is indicating disease and reaching an advanced stage, general hepatitis B and the chronic recurrence of hepatitis C be liver cirrhosis be many.
On tcm theory,, tympanites long-pending with costalgia, disease is main disease." costalgia " causes pain for depression of liver-QI, blood stasis stay due to the resistance or because of the hepatocholic depression thermal conductance causes the catharsis imbalance.See tangible caking in the abdomen and solid not moving is referred to as " disease is long-pending ", corresponding with it then is " abdominal mass is poly-", though tangible can moving.The long-pending pathomechanism of disease all is a deficiency in origin and excess in superficiality, and is very complicated." tympanites " then is that ascites hard postmenstruation appearred in liver, how by depressed emotion, accumulate in warm, the hepatopathy later stage causes liver,spleen,kidney three dirty all damages.Cause the disease that the stagnation of QI, blood stasis, wood hold, expose as characteristic with swell, venation sallow as drum, color of the leather of abdominal part, pathogenesis is a hepatopathy.With the passing of time thus the injured or eating and drinking without temperance of liver spleen, be addicted to drink excessively, the injured transformation failure of spleen person of taste, pathological changes is all dirty at liver,spleen,kidney three, and interacts, and causes in the long-pending abdomen of QI and blood water liquid disease.
Liver cirrhosis also has in chronic pathological process the acute pathological changes of appearance, as serious pathological changes such as acute yellow hepatic necrosis or massive hemorrhage occurs, also have the later stage because of the serious disease threat to life of hepatorenal syndrome occurring.The medicine of treatment hepatitis, cirrhotic ascites is a lot of at present, and when using as singles such as silybin, krestin, glucuronolatone, Radix Salviae Miltiorrhizae Tabellae, Herba Sedi granules, to the fibrosis DeGrain, the patient still transforms or form liver cirrhosis to liver cirrhosis after testing mostly.Through clinical practice in 30 years through proved recipe, having developed " regeneration live-nourishing ' yanggan ' pill " in " research of balance treatment treatment cancer and cirrhotic ascites " of founding becomes one of hardened serial patent medicine of the treatment various hepatopathy regulating liver-QI of hepatitis B.Establish this side and refine patent medicine in nineteen eighty-three.Mainly apply to hardened prevention of hepatic fibrosis regulating liver-QI and treatment, curative effect is good, solves the deficiency of its existing medicine.
Purpose of the present invention just provides a kind of preparation method for the treatment of various types of hepatitis, liver cirrhosis disease Chinese formulated products.
The objective of the invention is to realize through following technical scheme: according to the hepatitis disease is viral disease, and the hepatocyte that these viral characteristics are normal livers has lost functions such as original digestion, detoxifcation, protein metabolism, glycogen is synthetic because of pathological changes such as inflammation hyperemia, swelling, degeneration, necrosis.Pathological changes makes inside configuration such as lobules of liver, hepatocyte form fibrosis and tuberosity, tremulous pulse and vein have been pushed by the hypertrophy of fibrous tissue, cause the buckling of vessel deformity, change its course and cause that angiemphraxis, thrombosis, liver internal recycle are obstructed, blood supply is bad, therefore increase the weight of the infringement of liver again, caused hepatic necrosis, liver failure.At the cause of disease, pathology and pharmacology, suit the medicine to the illness selectedly have that tonify deficiency falls that enzyme is astringent or styptic treatment for spontaneous sweating, the purification of tcm of blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing, diuresis, detumescence, analgesic hemostatic, dissipating blood stasis, removing heat from blood, clearing away damp-heat, promoting the function of the gallbladder to alleviate jaundice, the body resistance strengthening and constitution consolidating, tonification the five internal organs effect processes the regeneration live-nourishing ' yanggan ' pill.
Adopt the regeneration live-nourishing ' yanggan ' pill of technique scheme preparation, verify through clinical practice: effective percentage reaches 86.5% (other drug only has 32.5%), and cure rate reaches 47% (other drug does not have the healing illustration).
One, prescription: (each crude drug weight is calculated by making 10000 ball patent medicine.)
Fructus Schisandrae Chinensis 5kg, Radix Salviae Miltiorrhizae 30kg, Radix Astragali 30kg, Radix Isatidis 20kg, Herba Verbenae 30kg, Herba Artemisiae Scopariae 50kg, Ganoderma 10kg, Radix Sophorae Tonkinensis 20kg, Radix Notoginseng 5kg.
Two, manufacture method:
1, Ganoderma, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, the Radix Astragali, Radix Isatidis, Herba Verbenae, Herba Artemisiae Scopariae, Radix Sophorae Tonkinensis are cut into slices or chopping, put suitable quantity of water and decoct 2 centrifugal removing slag, concentrate back merging, precipitation, filter, get supernatant concentration and become thick paste.
2, Radix Notoginseng is ground to the powder,, after 8 hours, be ground into fine powder, cross 80 mesh sieves and select capsule with 50 ℃ of freeze-day with constant temperature with above thick paste mix homogeneously.
3, this product capsule 's content is the sepia fine powder, bitter and puckery flavor.
4, basic specification: the 0.25g/ grain, 55/bottle, every is refined by crude drug 24.5g and to form.
5, packing: adopt sealing white glues bottle packing routine operation, the Chinese patent medicine ball.
Three, effect, purposes, usage:
1, effect:
This product has heat-clearing and toxic substances removing, the soft liver of nourishing the liver, antiinflammatory and falls enzyme, antiviral effect, levelling human body immunologic mechanism balance is arranged, leukocyte increasing, platelet and the proteic ratio of correction Archon are improved the effect of liver function, promotion liver cell regeneration, anti-hepatic fibrosis and control liver cirrhosis.
2, purposes:
The hardened control of hepatic fibrosis regulating liver-QI for the treatment of various types of hepatitis, liver cirrhosis but mainly hepatitis B being caused has unique curative effect.
3, usage:
Each 2-4 ball, three times on the one, warm water delivery service after meal.
Four, each medicine pharmacology analysis of filling a prescription:
1, Fructus Schisandrae Chinensis: the enzyme astringent drug falls in tonify deficiency
Pharmacological action: can strengthen cellular immune function, resisting fatigue, enhancing cerebral cortex excitement and process of inhibition make its balance.The effect that reduces low serum transaminase is arranged, keep hepatocyte and the substance metabolism obstacle that alleviates toxic hepatitis.
2, Radix Salviae Miltiorrhizae: drug for invigorating blood circulation and eliminating stasis
Pharmacological action: can improve immunologic function, microcirculation improvement obstacle, anticoagulant, antiinflammatory.The content of triglyceride in the hepatic tissue when obviously reducing acute and chronic hepatic injury serum transaminase vigor and alleviating hepatic injury.Promote liver cell regeneration, suppress the collagen fiber hypertrophy, prevent and treat liver cirrhosis.
3, Herba Verbenae: heat-clearing and toxic substances removing, diuresis, detumescence, dissipating blood stasis medicine
Pharmacological action: antibacterial analgesia, swelling diuretic effect are arranged.Be used for the treatment of hepatitis, cirrhotic ascites, especially the soft liver spleen that contracts had produce effects.
4, Radix Isatidis: heat-clearing and toxic substances removing, blood-cooling drugs
Pharmacological action: the effect of antibiotic, antiviral and raise immunity is arranged.In to the treatment of hepatitis B and hepatitis A, can play the effect that suppresses virus.
5, Herba Artemisiae Scopariae: clearing away damp-heat, promoting the function of the gallbladder to alleviate jaundice medicine
Pharmacological action: promoting the function of the gallbladder to alleviate jaundice, heat-clearing and toxic substances removing, anti-inflammatory analgetic, expansion bile duct, facilitating digestion, acceleration bile secretion and with drainage, promote the absorption of fat-soluble A, D, E, K, blood vessel dilating, improve microcirculation in the liver, prevent hepatic necrosis, promote liver cell regeneration.
6, Ganoderma: the body resistance strengthening and constitution consolidating, tonification the five internal organs medicine
Pharmacological action: the liver protecting function of detoxification and the effect that prevents steatosis are arranged, promote hepatic injury to recover.Ganoderan D
6Can promote the hepatocyte synthetic protein, improve hematopoietic function, help the enhancing body defence capability.
7, Radix Sophorae Tonkinensis: heat-clearing and toxic substances removing, reducing swelling and alleviating pain medicine
Pharmacological action: can alleviate and suppress hepatic tissue degeneration, necrosis, promote straight cell regeneration and reach the effect that protects the liver, inhibited to duplicating of hepatitis B virus simultaneously.
8, Radix Notoginseng: blood circulation promoting and blood stasis dispelling, analgesic hemostatic medicine
Pharmacological action: liver sclerosis and proteinic synthetic reaching are all had facilitation to liver cell regeneration.And the enzyme of falling is arranged and improve the hepatic protein metabolism and liver function has certain effect.
9, the Radix Astragali: QI invigorating drug supporting healthy energy
Pharmacological action: have the immunocompetence function.Show and activate the reticuloendothelial system phagocytic function, enhancing antibody nonspecific immunity function, thereby the immunologic balance of adjusting antibody.Reach the liver protecting, prevent that hepatic glycogen from reducing, promote the renewal of serum proteins, total protein and albumin amount are increased.
Claims (2)
1, a kind of Chinese formulated products and preparation method for the treatment of the hepatitis disease, it is characterized in that: it has the prescription that can cure all kinds of hepatitis, liver cirrhosis:
Fructus Schisandrae Chinensis 5kg, Radix Salviae Miltiorrhizae 30kg, Radix Astragali 30kg, Radix Isatidis 20kg, Herba Verbenae 30kg, Herba Artemisiae Scopariae 50kg, Ganoderma 10kg, Radix Sophorae Tonkinensis 20kg, Radix Notoginseng 5kg.
2, a kind of Chinese formulated products and preparation method for the treatment of the hepatitis disease, it is characterized in that: it has a manufacture method:
1. Ganoderma, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae, the Radix Astragali, Radix Isatidis, Herba Verbenae, Herba Artemisiae Scopariae, Radix Sophorae Tonkinensis are cut into slices or chopping, put suitable quantity of water and decoct 2 centrifugal removing slag, concentrate back merging, precipitation, filter, get supernatant concentration and become thick paste.
2. Radix Notoginseng is ground to the powder,, after 8 hours, be ground into fine powder, cross 80 mesh sieves and select capsule with 50 ℃ of freeze-day with constant temperature with above thick paste mix homogeneously.
3. this product capsule 's content is the sepia fine powder, bitter and puckery flavor.
4. basic specification: the 0.25g/ grain, 55/bottle, every is refined by crude drug 24.5g and to form.
5. packing: adopt sealing white glues bottle packing routine operation, the Chinese patent medicine ball.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99119384 CN1287857A (en) | 1999-09-14 | 1999-09-14 | Traditional Chinese patented medicine for treating hepatitis and its prepn. method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99119384 CN1287857A (en) | 1999-09-14 | 1999-09-14 | Traditional Chinese patented medicine for treating hepatitis and its prepn. method |
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| Publication Number | Publication Date |
|---|---|
| CN1287857A true CN1287857A (en) | 2001-03-21 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 99119384 Pending CN1287857A (en) | 1999-09-14 | 1999-09-14 | Traditional Chinese patented medicine for treating hepatitis and its prepn. method |
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| CN (1) | CN1287857A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007059250A3 (en) * | 2005-11-15 | 2007-09-13 | Access Business Group Int Llc | Plant-based formulations for improving liver health |
-
1999
- 1999-09-14 CN CN 99119384 patent/CN1287857A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007059250A3 (en) * | 2005-11-15 | 2007-09-13 | Access Business Group Int Llc | Plant-based formulations for improving liver health |
| US7419689B2 (en) | 2005-11-15 | 2008-09-02 | Access Business Group International Llc. | Plant-based formulations for improving liver health |
| CN101415433B (en) * | 2005-11-15 | 2013-01-30 | 捷通国际有限公司 | Plant-based formulations for improving liver health |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |