CN1287829A - Blood platelet storage bag and its mfg. method - Google Patents

Blood platelet storage bag and its mfg. method Download PDF

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Publication number
CN1287829A
CN1287829A CN 00125633 CN00125633A CN1287829A CN 1287829 A CN1287829 A CN 1287829A CN 00125633 CN00125633 CN 00125633 CN 00125633 A CN00125633 A CN 00125633A CN 1287829 A CN1287829 A CN 1287829A
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China
Prior art keywords
bag
blood vessel
diaphragm tube
blood
storage bag
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Granted
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CN 00125633
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Chinese (zh)
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CN1147283C (en
Inventor
姜跃琴
朗洁先
王庭全
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Shanghai Blood-Transfusion Technology Co., Ltd.
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BLOOD PRODUCTS AND TRANSFUSION APPARATUS MANAGEMENT CORP SHANGHAI BLOOD CENTRE
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Priority to CNB001256335A priority Critical patent/CN1147283C/en
Publication of CN1287829A publication Critical patent/CN1287829A/en
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Publication of CN1147283C publication Critical patent/CN1147283C/en
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Abstract

The present invention discloses thrombocyte preserving bag and its making method, both the blood inlet pipe and diaphram pipe are separated into two upper and lower, sections, the upper parts are made of PVC material, the lower parts are made of polyolefin, the upper part and lower part are connected by adhesive layer, the bag body is made of polyolefin, the blood inlet pipe and diaphram pipe adhered together by adhesive. The invented thrombocyte preserving bag possess the advantages of no extraneous matter settled out, easy processing and firmness of blood inlet pipe and diaphram pipe.

Description

Blood platelet storage bag and preparation method thereof
The present invention relates to the container of blood of human body collection, separation, filtration usefulness, more specifically refer to a kind of blood platelet storage bag and preparation method thereof.
Platelet transfusion is the complementary therapy that is used to stop blooding, prevent hemorrhage, chemotherapy and radiation treatment, very big practical value is arranged, because little, the fragile structure of volume of platelets, function complexity, self and external life-span short in life-span, extremely tight to external preservation condition requirement, the while platelet is based on aerobic metabolism, so requirement is preserved, and container is the least possible separates out its deleterious material, simultaneously has good gas-premeable etc. again, to prolong hematoblastic storage life.
Abroad just blood platelet storage bag is developed the eighties, what currently used blood platelet storage bag material was more is with special igelite or polyolefin, and China also is developed into the blood platelet storage bag of polrvinyl chloride at the beginning of 90.
The above-mentioned blood platelet storage bag made from igelite; though function admirable; especially the socket of transfusing blood; conduit is same pvc material; easy to process; sealing and fastness are good; but must select the auxiliary agent of multiple special kinds for use; thereby supplementary material purchased; processing; produce; detect to wait and to bring difficulty, and some auxiliary agent in use there be separating out in various degree, become a kind of foreign body to bring the patient; whether it is harmful not popular to people; low temperature resistant polyvinyl chloride is poor in addition, though-30 ℃ with interior have outside box protection, its breakage rate is also very big under the static condition of storage.And bag, advance the blood platelet storage bag that blood vessel, diaphragm tube all make with polyolefine material bag hard partially, opaque, processing technology is special, complicated; blood transfusion socket protective sleeve is with software thin film machinery cover type; easily come off, sealing is difficult to guarantee, and uses rather inconvenience.
For this reason, the objective of the invention is shortcoming, propose a kind of blood platelet storage bag and preparation method thereof at above-mentioned blood platelet storage bag existence.
To achieve these goals, the present invention adopts following technical scheme,
Blood platelet storage bag comprises bag, advances blood vessel, diaphragm tube, advancing blood vessel, diaphragm tube communicates from the upper end insertion bag of bag and with bag respectively, wherein: describedly advance blood vessel and diaphragm tube is divided into the upper and lower two-stage nitration, top all adopts pvc material to make, polyolefin is all adopted in the bottom, and top adopts adhesive layer to be connected with the bottom; Described bag adopts polyolefine material to make.
The blood platelet storage bag manufacture method is:
The polyolefin pellets of taking one-component is processed into the thin film bag;
Taking same one-component polyolefin pellets is processed into into blood vessel bottom and diaphragm tube bottom and inserts bag and it is connected with bag communicate;
Take polyvinyl chloride granules and be processed into into blood vessel top and diaphragm tube top;
To enter blood vessel top and diaphragm tube top respectively with to enter blood vessel bottom and diaphragm tube bottom mutually bonding with binding agent.
Another kind of manufacture method of the present invention is:
The polyolefin pellets of taking one-component is processed into the thin film bag;
Take same one-component polyolefin pellets and be processed into into blood vessel bottom and diaphragm tube bottom;
Take polyvinyl chloride granules and be processed into into blood vessel top and diaphragm tube top;
To enter blood vessel top and diaphragm tube top respectively with to enter blood vessel bottom and diaphragm tube bottom mutually bonding with binding agent;
Again bonding advance blood vessel and diaphragm tube after intact inserted bag and it be connected with the bag hot melt communicate.
Because blood platelet storage bag of the present invention will advance blood vessel and diaphragm tube is divided into the upper and lower two-stage nitration, top all adopts pvc material to make, and polyolefin is all adopted in the bottom, and top adopts adhesive layer to be connected with the bottom, and bag adopts polyolefine material to make.Polyolefin pellets with one-component is processed into the thin film bag, enter blood vessel bottom and diaphragm tube bottom and insert bag makes it be connected with bag to communicate, still be processed into into blood vessel top and diaphragm tube top, and will enter blood vessel top and diaphragm tube top respectively with to enter blood vessel bottom and diaphragm tube bottom mutually bonding with binding agent with polyvinyl chloride granules.Therefore, blood platelet storage bag of the present invention can overcome the shortcoming that traditional blood platelet storage bag exists effectively, can keep making bag and have and do not have the advantage that foreign body folded and brought the patient, can keep making into blood vessel and diaphragm tube again and have easy to process, good airproof performance and the good advantage of fastness with pvc material with polyolefin.
Below in conjunction with drawings and Examples, the present invention is done one explains:
Fig. 1 is a blood platelet storage bag structural representation of the present invention.
Fig. 2 advances the blood vessel structure enlarged diagram for blood platelet storage bag of the present invention.
Fig. 3 is a blood platelet storage bag diaphragm tube structure enlarged diagram of the present invention.
See also Fig. 1 and in conjunction with Fig. 2, shown in Figure 3, this storage bag comprises bag 1, advance blood vessel 2, diaphragm tube 3, advance blood vessel 2, diaphragm tube 3 inserts bag from the upper end of bag 1 respectively and communicates with bag 1, describedly advance blood vessel 2 and be divided into top 21 and bottom 22 two-stage nitration, diaphragm tube 3 also is divided into top 31 and bottom 32 two-stage nitration, enter blood vessel top 21, diaphragm tube top 31 all adopts pvc material to make, enter blood vessel bottom 22,32 all adopt polyolefin under the diaphragm tube, enter the top 21 and bottom 22 of blood vessel 2, and being connected between the top 31 of diaphragm tube 3 and the bottom 32 adopt adhesive layer 23,33 are connected.In the present invention, described bag 1 also adopts polyolefine material to make.
Above-mentioned bag 1, advance the polyolefine material that blood vessel bottom 22 and diaphragm tube bottom 32 is adopted and to select ethylene-vinyl acetate copolymer for use.
Described bag 1 with enter blood vessel bottom 22 and diaphragm tube bottom 32 can be one machine-shaping, also can with bag 1 with enter blood vessel bottom 22 and diaphragm tube bottom 32 processes respectively, and then will enter the upper end that blood vessel bottom 22 and diaphragm tube 32 are fused to bag 1 respectively.
The manufacture method of blood platelet storage bag of the present invention specifically describes as follows:
The polyolefin pellets of taking one-component is processed into thin film bag 1, and processing mode can carry out on blow moulding machine, Packing Machine or casting machine;
Take same one-component polyolefin pellets and be processed into into blood vessel bottom 22 and diaphragm tube bottom 32, as on extruder, being blow molded into conduit, insert bag then and it is connected with bag 1 hot melt communicate, or polyvinyl chloride film connects with the high-frequency electrical heat seal and to communicate as medium on bag 1 upper end pad;
Take polyvinyl chloride granules and be processed into into blood vessel top 21 and diaphragm tube top 31, enter blood vessel top 21 and diaphragm tube top 31 as blowing conduit conduct on extruder;
After the top and the bottom 32,31 of treat above-mentioned bag 1, advancing the top and the bottom 22,21 of blood vessel and diaphragm tube have made, the reuse binding agent will advance blood vessel top 21 and diaphragm tube top 31 respectively with enter blood vessel bottom 22 and diaphragm tube bottom 32 is mutually bonding.
Above-mentioned manufacture method is according to the priority of step, also can top and the bottom 31,32 that advance the top and the bottom 21,22 of blood vessel and diaphragm tube are bonding in advance, again advance blood vessel 2 and 3 upper ends of inserting bags 1 after bonding are made it be connected with bag 1 hot melt to communicate.
On bonding mode, be coated in into blood vessel upper and lower part 21,22 and 31,32 connections, diaphragm tube upper and lower part with photosensitive adhesive, just the adhesive layer among Fig. 1 23,33, and make into blood vessel top and the bottom 21,22 and diaphragm tube top and the bottom 31,32 bonding mutually.
Advance blood vessel 2 and diaphragm tube 3 position of the adhesive layer 23,33 that advances blood vessel 2 and diaphragm tube 3 (just over against) that bonding between the top and the bottom 31,32 that add F.F. blood vessel top and the bottom 21,22 and diaphragm tube, available Photocureable instrument will apply behind the photosensitive adhesive carry out irradiation.
Described diaphragm tube top 31 comprises membrane layer, the place of twisting off and sealing guaranteeing that bag 1 is hedged off from the outer world, frangibility and closely cooperate with blood exchange transfusion set's perforator and to play the effect of blood transfusion socket when infusion.
The blood platelet storage bag that utilizes method of the present invention to make, used bag material component is single, physicochemical property stable, is as good as deposits yields, and platelet was preserved 5-7 days under the suitable room temperature, suitable again profound hypothermia (negative 196 degree Celsius) is the long preservation platelet down, and bag can be not damaged.Production and processing is convenient, easily expansion is produced, and is rational in infrastructure, particularly also very convenient in the use, as, advance sealing of blood vessel 2 and diaphragm tube 3 and need only common thermal jointing clipper.

Claims (7)

1, a kind of blood platelet storage bag, this storage bag comprises bag, advances blood vessel, diaphragm tube, advancing blood vessel, diaphragm tube communicates from the top insertion bag of bag and with bag respectively, it is characterized in that: describedly advance blood vessel and diaphragm tube is divided into the upper and lower two-stage nitration, top all adopts pvc material to make, polyolefin is all adopted in the bottom, and top adopts adhesive layer to be connected with the bottom; Described bag adopts polyolefine material to make.
2, blood platelet storage bag as claimed in claim 1 is characterized in that: described bag, enter blood vessel bottom and diaphragm tube bottom and adopt ethylene-vinyl acetate copolymer.
3, blood platelet storage bag as claimed in claim 1 or 2 is characterized in that: described bag with enter the blood vessel bottom and the diaphragm tube bottom can be formed in one.
4, a kind of blood platelet storage bag manufacture method is characterized in that:
The polyolefin pellets of taking one-component is processed into the thin film bag;
Taking same one-component polyolefin pellets is processed into into blood vessel bottom and diaphragm tube bottom and inserts bag and it is connected with bag communicate;
Take polyvinyl chloride granules and be processed into into blood vessel top and diaphragm tube top;
To enter blood vessel top and diaphragm tube top respectively with to enter blood vessel bottom and diaphragm tube bottom mutually bonding with binding agent.
5, a kind of blood platelet storage bag manufacture method is characterized in that:
The polyolefin pellets of taking one-component is processed into the thin film bag;
Take same one-component polyolefin pellets and be processed into into blood vessel bottom and diaphragm tube bottom;
Take polyvinyl chloride granules and be processed into into blood vessel top and diaphragm tube top;
To enter blood vessel top and diaphragm tube top respectively with to enter blood vessel bottom and diaphragm tube bottom mutually bonding with binding agent;
Again bonding advance blood vessel and diaphragm tube after intact inserted bag and it be connected with the bag hot melt communicate.
6, as claim 4 or 5 described blood platelet storage bag manufacture methods, it is characterized in that: be coated in into the blood vessel upper and lower part with connection, diaphragm tube upper and lower part and make that into the blood vessel top and the bottom are mutually bonding with the diaphragm tube top and the bottom with photosensitive adhesive.
7, blood platelet storage bag manufacture method as claimed in claim 6 is characterized in that: with Photocureable instrument will apply behind the photosensitive adhesive advance blood vessel and diaphragm tube carries out irradiation.
CNB001256335A 2000-10-10 2000-10-10 Blood platelet storage bag and its mfg. method Expired - Lifetime CN1147283C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB001256335A CN1147283C (en) 2000-10-10 2000-10-10 Blood platelet storage bag and its mfg. method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB001256335A CN1147283C (en) 2000-10-10 2000-10-10 Blood platelet storage bag and its mfg. method

Publications (2)

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CN1287829A true CN1287829A (en) 2001-03-21
CN1147283C CN1147283C (en) 2004-04-28

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CNB001256335A Expired - Lifetime CN1147283C (en) 2000-10-10 2000-10-10 Blood platelet storage bag and its mfg. method

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101861858A (en) * 2010-05-26 2010-10-20 金卫医疗科技(上海)有限公司 Medical profound hypothermia storage bag having function of protecting liquid inlet pipe
CN101869100A (en) * 2010-05-26 2010-10-27 金卫医疗科技(上海)有限公司 Low-temperature preservation bag

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101861858A (en) * 2010-05-26 2010-10-20 金卫医疗科技(上海)有限公司 Medical profound hypothermia storage bag having function of protecting liquid inlet pipe
CN101869100A (en) * 2010-05-26 2010-10-27 金卫医疗科技(上海)有限公司 Low-temperature preservation bag
CN101869100B (en) * 2010-05-26 2014-01-29 金卫医疗科技(上海)有限公司 Low-temperature preservation bag

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Owner name: SHANGHAI BLOOD TRANSFUSION TECHNOLOGY CO., LTD.

Free format text: FORMER OWNER: BLOOD PRODUCTS AND BLOOD TRASFUSION EQUIPMENT AND MATERIALS CORP. OF SHANGHAI BL

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Address after: 200051 No. 1191, Hongqiao Road, Shanghai

Applicant after: Shanghai Blood-Transfusion Technology Co., Ltd.

Address before: 200051 No. 1191, Hongqiao Road, Shanghai

Applicant before: Blood Products and Transfusion Apparatus Management Corp., Shanghai Blood Centre

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Granted publication date: 20040428