CN1287805C - Formula of anti-senility tablet and preparing method - Google Patents

Formula of anti-senility tablet and preparing method Download PDF

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Publication number
CN1287805C
CN1287805C CNB031230083A CN03123008A CN1287805C CN 1287805 C CN1287805 C CN 1287805C CN B031230083 A CNB031230083 A CN B031230083A CN 03123008 A CN03123008 A CN 03123008A CN 1287805 C CN1287805 C CN 1287805C
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vitamin
tablet formulation
age
age tablet
described anti
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CN1457800A (en
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毛爱民
陈温平
侯佳茵
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CGABGCHENG CHUANGZHI BIOLOGICAL SCIENCE AND TECHNOLOGY Co Ltd BEIJING
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CGABGCHENG CHUANGZHI BIOLOGICAL SCIENCE AND TECHNOLOGY Co Ltd BEIJING
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Abstract

The present invention relates to a formula of antiageing tablets and a preparation method thereof, which relate to the technical field of health products. Vitamin A, B1, B2, B6, B12, C, D and E, ferrous fumarate, sodium selenite, zinc oxide, potassium iodide, nicotinic acid, pantothenic acid, meal cellulose, aspartame, mannitol, lactose and citric acid are used as raw material. The finished product of the antiageing tablets is obtained by metering, premixing and triturating the raw material, making particles, drying, adding magnesium stearate and orange powder essence, totally mixing, determining the tablet weight, pressing into tablets, coating the tablets by using a film coating agent, testing and packaging. The present invention is used for antiageing and health care. The present invention has the characteristics of a plurality of nutrition components, scientific and reasonable formula, broad-spectrum efficiency, easy absorption, simple method, easy popularization, etc. The present invention can be used singly or used by combining with other health products.

Description

The prescription of anti-age tablet formulation and manufacture method
Technical field
The prescription of anti-age tablet formulation of the present invention and manufacture method relate to health product technology field, particularly the prescription of anti-age tablet formulation and manufacture method technical field.
Background technology
At present, in health product technology field, to have with the alpha-linolenic acid be the health product of base material, be the health product of base material with the gamma-Linolenic acid, be the health product of base material with lecithin, with calcium or zinc or ferrum or selenium ... wait the health product that are respectively base material, or be the health product that base material combines with edible carrier again with above-mentioned one or both materials, though varied, various in style, drawback such as exist all that nutrient formulation is simple, usefulness is single, human body is difficult for absorbing or absorption rate is low.The applicant passes through from " United States Patent (USP) data base " and " MBDLINE data base " online information retrieval, by looking into newly, all do not detect documents and materials related to the present invention from " health protection with Chinese medicine product data base ", " Chinese science and technology periodical Chinese medicine literature index ", " foreign medical science " and retrievals such as " the above medical hygiene scientific and technological achievement of portion data bases since the establishment of the nation ".At present, does not still have both at home and abroad and the project report of the akin research and development of the present invention.The present invention be exactly look into through extensive retrieval new after, take into full account the problems referred to above, conscientiously solve on the above-mentioned drawback basis and study successfully.
Summary of the invention
The prescription and the manufacture method that the purpose of this invention is to provide a kind of anti-age tablet formulation.For this reason, provide a kind of new health product, thereby reach following purpose:
1, make anti-age tablet formulation new varieties provided by the invention contain that general nutritional labeling is many, scientific formulation is reasonable, manufacture method is simple and easy to utilize;
2, make antisenescence health product new varieties usefulness wide spectrum provided by the invention, adaptation colony greatly and extensively;
3, make antisenescence health product new varieties provided by the invention be easy to absorption of human body, effectively improve absorption rate, give full play to its antidotal health-care effect;
4, make antisenescence health product new varieties provided by the invention both can be used as independent antisenescence health product and eat, can combine edible simultaneously again with other health product; Combining with other health product when edible, as both eating alpha-linolenic acid health product or lecithin health product ..., eat anti-age tablet formulation health product provided by the invention again, thereby formed the health product eating method of cocktail type, play the full method anti-ageing healthcare effect of cocktail type.
The present invention can accomplish the end in view.
For achieving the above object, technical scheme provided by the invention is: a kind of prescription of anti-age tablet formulation and manufacture method, the manufacture method that comprises the prescription and the anti-age tablet formulation of anti-age tablet formulation, the prescription of described anti-age tablet formulation comprises by vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, vitamin D, the composite edible vitamin that vitamin E is formed, by fumarate ferrum, sodium selenite, zinc oxide, potassium iodide, the composite edible mineral that the human body that magnesium stearate is formed need be taken in, by nicotinic acid, the composite edible trace element that pantothenic acid is formed, the nutrition compatibility that is anti-age tablet formulation is again the dietary cellulose of antiageing tablet agent carrier, by aspartame, mannitol, the composite edible sweeting agent that lactose is formed, the citric acid edible acidic flavoring agent, orange powder essence edible essence perfume agent, the manufacture method of described anti-age tablet formulation is with vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, vitamin D, vitamin E, ferrous fumarate, sodium selenite, zinc oxide, potassium iodide, nicotinic acid, pantothenic acid, dietary cellulose, aspartame, mannitol, lactose, the citric acid raw material carries out premix after metering according to ratio requirement, premix is after levigation system granule, make behind the granule drying adds pulverous magnesium stearate raw material and orange powder essence carries out always mixing, total mixing after determine that sheet heavily carries out tabletting, carry out overlay film with film coating agent behind the tabletting, overlay film obtains the anti-age tablet formulation finished product after check is packed.
The proportioning of described antiageing tablet agent prescription is (as a following table):
Classification Composition Consumption Classification Composition Consumption
Composite edible vitamin Vitamin A 0.3-0.6 Composite edible mineral Potassium iodide 0.032-0.035
Vitamin B1 0.5-0.8 Magnesium stearate 3.1-3.5
Vitamin B2 0.6-0.9 Composite edible trace element Nicotinic acid 2-5
Vitamin B6 0.5-0.7 Pantothenic acid 0.4-0.7
Vitamin B12 0.001-0.003 Dietary fiber Dietary cellulose 294-297
Vitamin C 14-17 Composite edible sweeting agent Aspartame 2-5
Vitamin D 0.001-0.003 Mannitol 54-57
Vitamin E 5-8 Lactose 194-197
Composite edible mineral Ferrous fumarate 4.6-4.9 Edible acidic flavoring agent Citric acid 4-7
Sodium selenite 0.11-0.14 Edible essence spice Orange powder essence 5-8
Zinc oxide 12.4-12.7
Annotate: be the consumption proportion of 1000 anti-age tablet formulations in the table; Consumption unit is g.
The levigation fineness degree of described anti-age tablet formulation manufacture method is 20 order to 50 orders.
The dry back moisture of described anti-age tablet formulation manufacture method is 6% to 8%.
Described anti-age tablet formulation manufacture method is after drying, and adding is the nutrition compatibility Powdered magnesium stearate of lubricate in anti-age tablet formulation again of anti-age tablet formulation, carries out always mixing after also adding orange powder essence simultaneously.
The stator of described anti-age tablet formulation manufacture method heavily is every heavy 0.5g to 0.8g.
Carry out overlay film with film coating agent behind the tabletting of described anti-age tablet formulation manufacture method, its overlay film amount is weightening finish 2.5% to 4.5% on antiageing tablet heart agent basis.
Owing to adopted technical scheme provided by the present invention, made the prescription of anti-age tablet formulation of the present invention and manufacture method have following beneficial effect:
1, because the present invention research is set with vitamin A, thus obtained to keep the human body epithelial tissue normal configuration and function, keep visual performance and prevent antidotal beneficial effects such as nyctalopia, raising immune function;
2, because the present invention's research is set with vitamin B1, thereby obtain the coenzyme of plurality of enzymes in the human body, had the appetite kept, the elasticity of muscle and healthy antidotal beneficial effects such as the mental status;
3, because the present invention research is set with vitamin B2, thereby obtain to participate in the metabolism of human amino acid, fat, carbohydrate, participated in the retina metabolism and help photopia, helped antidotal beneficial effects such as skin histology growth;
4, because the present invention is set with vitamin B6, it plays a part to shift amino through phosphorylation in vivo;
5, because the present invention's research is set with vitamin B12, thereby obtain to promote proteinic biosynthesis, promoted red blood cell development and sophisticated beneficial effect;
6, because the present invention's research is set with vitamin C, thereby obtain the multinomial metabolic process of participation human body, promoted the absorption of ferrum, improved antidotal beneficial effects such as human body resistance;
7,, thereby obtained to promote the calcium phosphorus of human body to absorb, promoted the osseous tissue calcification, prevented antidotal beneficial effect such as osteoporosis because the present invention research is set with vitamin D;
8,, thereby the structure and the functional completeness of human cell tissue, the defying age beneficial effect of raise immunity have been obtained to keep because the present invention's research is set with vitamin E, and it is a most important antioxidant in the human body;
9, because the present invention's research is set with ferrous fumarate, thereby obtain the raising hematochrome, promoted erythropoiesis and hemoglobin function, eliminated antidotal beneficial effects such as iron deficiency anemia;
10, because the present invention research is set with sodium selenite, thereby obtained to keep the normal heart function, protective tissue is not damaged by noxious substance, and prevents the antidotal beneficial effects such as formation of peroxide with vitamin E;
11, because the present invention's research is set with zinc oxide, it is and the composition that digests and absorb relevant several different enzyme systems, thereby obtained the effect of zinc supplement, safeguard the normal of skin, skeleton and hair, improve body immune function, safeguard antidotal beneficial effects such as sense organ nervous system such as the sense of taste;
12,, thereby obtained to safeguard the defying age beneficial effect of thyroid normal physiological function because the present invention's research is set with potassium iodide, and it has the function of regulating multinomial physiological metabolism process;
13, because the present invention research is set with nicotinic acid, it is a coenzyme crucial in the energy metabolism, thereby has obtained influence and promoted antidotal beneficial effects such as protein, fat and DHA be synthetic;
14,, thereby obtained influence and promoted antidotal beneficial effects such as metabolism and neurodevelopment because the present invention's research is set with pantothenic acid, and it is the prothetic group of many important enzymes;
15, because the present invention research is set with dietary cellulose, thereby obtain to prevent constipation, anticancer effect, reduced the antidotal beneficial effects such as effect that plasma cholesterol prevents the cardiovascular diseases; Also this anti-age tablet formulation is played the beneficial effect of carrier function simultaneously;
16,, thereby obtained to increase the beneficial effect of trace element because the present invention's research is set with magnesium stearate; Have lubrication owing to pulverous magnesium stearate simultaneously, thereby obtained to make the beneficial effect of various adjuvant mix homogeneously;
17,, thereby obtained the moderate beneficial effect of taste because the present invention's research is set with aspartame, mannitol, lactose, citric acid, orange powder essence;
18, since the present invention research be set with film coating agent and carry out overlay film, thereby obtained when edible smoothly, be convenient to the beneficial effect that eats, is easy to preserve;
19,, thereby making, beneficial effect easy to utilize have been obtained to be beneficial to because the manufacture method that the present invention sets is simple, workable.
Figure of description
Figure of description is the prescription of anti-age tablet formulation of the present invention and the technological process window sketch map of manufacture method.
The specific embodiment
Below in conjunction with Figure of description, prescription and manufacture method to anti-age tablet formulation of the present invention are described in detail, shown in Figure of description: a kind of prescription of anti-age tablet formulation and manufacture method, the manufacture method that comprises the prescription and the anti-age tablet formulation of anti-age tablet formulation, the prescription of described anti-age tablet formulation comprises by vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, vitamin D, the composite edible vitamin that vitamin E is formed, by fumarate ferrum, sodium selenite, zinc oxide, potassium iodide, the composite edible mineral that the human body that magnesium stearate is formed need be taken in, by nicotinic acid, the composite edible trace element that pantothenic acid is formed, the nutrition compatibility that is anti-age tablet formulation is again the dietary cellulose of antiageing tablet agent carrier, by aspartame, mannitol, the composite edible sweeting agent that lactose is formed, the citric acid edible acidic flavoring agent, orange powder essence edible essence perfume agent, the manufacture method of described anti-age tablet formulation is with vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, vitamin D, vitamin E, ferrous fumarate, sodium selenite, zinc oxide, potassium iodide, nicotinic acid, pantothenic acid, dietary cellulose, aspartame, mannitol, lactose, the citric acid raw material carries out premix after metering according to ratio requirement, premix is after levigation system granule, make behind the granule drying adds pulverous magnesium stearate raw material and orange powder essence carries out always mixing, total mixing after determine that sheet heavily carries out tabletting, carry out overlay film with film coating agent behind the tabletting, overlay film obtains the anti-age tablet formulation finished product after check is packed.
The proportioning of described antiageing tablet agent prescription is (as a following table):
Classification Composition Consumption Classification Composition Consumption
Composite edible vitamin Vitamin A 0.3-0.6 Composite edible mineral Potassium iodide 0.032-0.035
Vitamin B1 0.5-0.8 Magnesium stearate 3.1-3.5
Vitamin B2 0.6-0.9 Composite edible trace element Nicotinic acid 2-5
Vitamin B6 0.5-0.7 Pantothenic acid 0.4-0.7
Vitamin B12 0.001-0.003 Dietary fiber Dietary cellulose 294-297
Vitamin C 14-17 Composite edible sweeting agent Aspartame 2-5
Vitamin D 0.001-0.003 Mannitol 54-57
Vitamin E 5-8 Lactose 194-197
Composite edible mineral Ferrous fumarate 4.6-4.9 Edible acidic flavoring agent Citric acid 4-7
Sodium selenite 0.11-0.14 Edible essence spice Orange powder essence 5-8
Zinc oxide 12.4-12.7
Annotate: be the consumption proportion of 1000 anti-age tablet formulations in the table; Consumption unit is g.
The levigation fineness degree of described anti-age tablet formulation manufacture method is 20 order to 50 orders.
The dry back moisture of described anti-age tablet formulation manufacture method is 6% to 8%.
Described anti-age tablet formulation manufacture method is after drying, and adding is the nutrition compatibility Powdered magnesium stearate of lubricate in anti-age tablet formulation again of anti-age tablet formulation, carries out always mixing after also adding orange powder essence simultaneously.
The stator of described anti-age tablet formulation manufacture method heavily is every heavy 0.5g to 0.8g.
Carry out overlay film with film coating agent behind the tabletting of described anti-age tablet formulation manufacture method, its overlay film amount is weightening finish 2.5% to 4.5% on antiageing tablet heart agent basis.
Embodiment 1
By shown in the above and the Figure of description, the present invention is made, be example to make 1,000 left and right sides anti-age tablet formulations, the according to the form below proportioning is raw material and measures:
Vitamin A: 0.4g Vitamin E: 6g Dietary cellulose: 295g
Vitamin B1: 0.6g Ferrous fumarate: 4.7g Aspartame: 3g
Vitamin B2: 0.7g Sodium selenite: 0.12g Mannitol: 55g
Vitamin B6: 0.5g Zinc oxide: 12.5g Lactose: 195g
Vitamin B12: 0.001g Potassium iodide: 0.033g Citric acid: 5g
Vitamin C: 15g Nicotinic acid: 3g
Vitamin D: 0.001g Pantothenic acid: 0.5g
By last table proportioning is to give premix after raw material measures, carry out levigation behind the premix, the fineness degree of levigation is 40 orders, levigation is after the system granule carries out drying, dried moisture is 6%, dry back adds the 3.3g magnesium stearate and 6g orange powder essence carries out always mixing, total back of mixing determines that every heavy 0.6 gram carries out tabletting, carry out overlay film with film coating agent behind the tabletting, the overlay film amount is grasped the 3%-4% that increases weight on antiageing tablet heart agent weight basis, carry out tablet weight variation behind the overlay film, sense organ, each nutrient composition content of anti-age tablet formulation etc. embody the quality inspection of quality, and the bacterium inspection that embodies hygienic quality, pack after the check, after packing, obtain the anti-age tablet formulation finished product.Through the good result that obtains expection on probation.The those of ordinary skill of all industry all can be implemented the present invention by shown in the above and the Figure of description.
Embodiment 2
By embodiment 1 described the operation, just the following table proportioning is raw material and metering:
Vitamin A: 0.3g Vitamin E: 5g Dietary cellulose: 294g
Vitamin B1: 0.5g Ferrous fumarate: 4.6g Aspartame: 2g
Vitamin B2: 0.6g Sodium selenite: 0.11g Mannitol: 54g
Vitamin B6: 0.5g Zinc oxide: 12.4g Lactose: 194g
Vitamin B12: 0.001g Potassium iodide: 0.032g Citric acid: 4g
Vitamin C: 14g Nicotinic acid: 3g
Vitamin D: 0.001g Pantothenic acid: 0.4g
Received the good result of expection equally.
Embodiment 3
By embodiment 1 described the operation, just the following table proportioning is raw material and metering:
Vitamin 1:0.6g Vitamin E: 8g Dietary cellulose: 297g
Vitamin B1: 0.8g Ferrous fumarate: 4.9g Aspartame: 5g
Vitamin B2: 0.9g Sodium selenite: 0.14g Mannitol: 57g
Vitamin B6: 0.7g Zinc oxide: 12.7g Lactose: 197g
Vitamin B12: 0.003g Potassium iodide: 0.035g Citric acid: 7g
Vitamin C: 17g Nicotinic acid: 5g
Vitamin D: 0.003g Pantothenic acid: 0.7g
Received the good result of expection equally.

Claims (6)

1, a kind of anti-age tablet formulation, it is characterized in that: described anti-age tablet formulation comprises by vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, vitamin D, the composite edible vitamin that vitamin E is formed, by ferrous fumarate, sodium selenite, zinc oxide, potassium iodide, the composite edible mineral that the human body that magnesium stearate is formed need be taken in, by nicotinic acid, the composite edible trace element that pantothenic acid is formed, the nutrition compatibility that is anti-age tablet formulation is again the dietary cellulose of antiageing tablet agent carrier, by aspartame, mannitol, the composite edible sweeting agent that lactose is formed, citric acid, orange powder essence; Containing vitamin A in per 1000 of described anti-age tablet formulation is 0.3-0.6g, vitamin B1 is 0.5-0.8g, vitamin B2 is 0.6-0.9g, vitamin B6 is 0.5-0.7g, vitamin B12 is 0.001-0.003g, vitamin C is 14-17g, vitamin D is 0.001-0.003g, vitamin E is 5-8g, ferrous fumarate is 4.6-4.9g, sodium selenite is 0.11-0.14g, zinc oxide is 12.4-12.7g, potassium iodide is 0.032-0.035g, magnesium stearate is 3.1-3.5g, nicotinic acid is 2-5g, pantothenic acid is 0.4-0.7g, dietary cellulose is 294-297g, aspartame is 2-5g, mannitol is 54-57g, lactose is 194-197g, citric acid is 4-7g, orange powder essence is 5-8g.
2, according to the described anti-age tablet formulation of claim 1, it is characterized in that: containing vitamin A in per 1000 of described anti-age tablet formulation is 0.3-0.6g, vitamin B1 is 0.5-0.8g, vitamin B2 is 0.6-0.9g, vitamin B6 is 0.5-0.7g, vitamin B12 is 0.001-0.003g, vitamin C is 14-17g, vitamin D is 0.001-0.003g, vitamin E is 5-8g, ferrous fumarate is 4.6-4.9g, sodium selenite is 0.11-0.14g, zinc oxide is 12.4-12.7g, potassium iodide is 0.032-0.035g, magnesium stearate is 3.1-3.5g, nicotinic acid is 2-5g, pantothenic acid is 0.4-0.7g, dietary cellulose is 294-297g, aspartame is 2-5g, mannitol is 54-57g, lactose is 194-197g, citric acid is 4-7g, orange powder essence is 5-8g; Described anti-age tablet formulation is with vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin B12, vitamin C, vitamin D, vitamin E, ferrous fumarate, sodium selenite, zinc oxide, potassium iodide, nicotinic acid, pantothenic acid, dietary cellulose, aspartame, mannitol, lactose, the citric acid raw material carries out premix after metering according to ratio requirement, premix is after levigation system granule, make behind the granule drying adds pulverous magnesium stearate raw material and orange powder essence carries out always mixing, total mixing after determine that sheet heavily carries out tabletting, carry out overlay film with film coating agent behind the tabletting, overlay film obtains the anti-age tablet formulation finished product after check is packed.
3, anti-age tablet formulation according to claim 1 is characterized in that: the fineness degree of described anti-age tablet formulation levigation when making is 20 order to 50 orders.
4, anti-age tablet formulation according to claim 1 is characterized in that: described anti-age tablet formulation dried moisture when making is 6% to 8%.
5, anti-age tablet formulation according to claim 1 is characterized in that: described anti-age tablet formulation is every heavy 0.5g to 0.8g when making.
6, anti-age tablet formulation according to claim 1 is characterized in that: described anti-age tablet formulation carries out overlay film with film coating agent behind the tabletting when making, and its overlay film amount is weightening finish 2.5% to 4.5% on antiageing tablet heart agent basis.
CNB031230083A 2003-04-25 2003-04-25 Formula of anti-senility tablet and preparing method Expired - Fee Related CN1287805C (en)

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CN1287805C true CN1287805C (en) 2006-12-06

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Publication number Priority date Publication date Assignee Title
CN1985848B (en) * 2005-12-20 2010-11-24 张金科 Compound vitamin and mineral preparation for prenatal taking
CN100394922C (en) * 2006-04-04 2008-06-18 郑海鸿 Toxicity-expelling fibrous nutrient and its prepn. method

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