CN1270052A - Medicinal composition for relieving sexual fatigue and delaying sanility and preparing process thereof - Google Patents
Medicinal composition for relieving sexual fatigue and delaying sanility and preparing process thereof Download PDFInfo
- Publication number
- CN1270052A CN1270052A CN99105729A CN99105729A CN1270052A CN 1270052 A CN1270052 A CN 1270052A CN 99105729 A CN99105729 A CN 99105729A CN 99105729 A CN99105729 A CN 99105729A CN 1270052 A CN1270052 A CN 1270052A
- Authority
- CN
- China
- Prior art keywords
- weight portion
- medicine
- weight
- antidotal
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A medicine composition for relieving sexual fatigue and delaying sanility is prepared from 7 raw materials including animal's brain tissue, water, baby's urine, musk, glucose, etc. If it is used to cure impotence, it features high cure rate, short course of treatment and no recurrence. It can also improve human immunity.
Description
The present invention relates to a kind of anti-exhaustion due to sexual indulgence, antidotal pharmaceutical composition and preparation method thereof, relate in particular to a kind of pharmaceutical composition of making by Radix Rhodiolae Yunnanensis, animal brain, water, pupil urine, baby's fetal hair (Crinis Carbonisatus) charcoal, Moschus and glucose, and this preparation of drug combination method.
In the daily life, exhaustion due to sexual indulgence, fatigue and aging are recurrent.Along with the raising of living standards of the people, people are more and more stronger in the requirement of aspects such as happy feelings taste desire, allaying tiredness, slow down aging, good health and a long life.For the treatment of sexual impotence, about the good clinical experiment report of male's control seldom, and the effectiveness of oral drugs is very low.Adopted a lot of hormone medicines both at home and abroad, but these medicines cure the symptoms, not the disease all, take for a long time, also can cause renal failure.Can bring out erection though there are a lot of different medicines to demonstrate, they are just afterwards just effective in being injected directly into penis.Current therapy is based on to the vasoactive material of intracavernous injection, obtained good result as phenoxy group benzene methanamine, phentolamine, papaverine, but these medicines can cause penile pain and fibre deformation with the medication of penis cavernosa injection method the time.Another approach that substitutes at the cavernous body of penis innerlich anwenden is that penis is smeared glyceryl trinitrate, and it also demonstrates effectively, but to patient and the equal toxic side effect of spouse.The Pyrazolopyrimidinonefor of Pfizer Research and Development Company (popular name " viagra ") medicine, treatment sexual impotence has the comparison obvious effect, but bigger side effect is also arranged, and for example has and takes " viagra " lethal many reports.
At the beginning of 1990's, Wisconsin medical college Denier professor De Laweiman develops the growth hormone therapy and can seek to attempt the trial that poliosis blackening, skin are tenderized with the injection novocain to Romanian Gerontological Research Center; The synthetic liquid of recommending from UNESCO in 1992 of Bulbus Allii ethanol promote to return virgin prescription to Paris, FRA Mo Lisidejiama development not long ago attempt reverse that human body skin and muscle cell are aged to return virgin hormone drug JEVNESERA, numerously in the world wide return virgin development test and all fail radical change internal organs organ dysfunction and physiological age, and mostly with chemical hormone test, one extends stops annotating hormone, reinstatement again.The scientific worker of China the world of medicine is carrying out extensive work aspect the research of defying age medicine and the clinical practice.Wherein, China made brilliant achievements on anti-ageing theory of Chinese medicine, Chinese patent medicine health care and applied research since 1988, had demonstrated the distinctive advantage of China.At present, anti-senile preparation is various in style both at home and abroad.CN 112788A discloses a kind of health oral liquid of glossy ganoderma, but this invention only is the medicine simple addition with benefiting action more well known in the art, and nothing can compellent concrete effect.CN 1093956A discloses a kind of marrow oral liquor, has the function of enriching yin and nourishing kidney.But, because a little less than little, the efficacy of a drug of this medicine drug effect, for defying age, keep fit, diseases prevention need take for a long time just and may take effect, and effect can be not clearly.In a word, the mechanism of action of present antiaging agent and clinical practice aspect lack clear and definite and objective standard really has definite curative effect person still less.
An object of the present invention is to provide that a kind of consumption is little, strong drug action, the anti-exhaustion due to sexual indulgence for the treatment of both the principal and secondary aspects of a disease, antidotal pure Chinese medicinal preparation.Said preparation is without any side effects.
Another object of the present invention provides the preparation method of this pharmaceutical preparation.
Solution of the present invention mainly is based on pathogenetic understanding and the Therapeutic Principle of motherland's medical science to exhaustion due to sexual indulgence, aging, and by handed down from the older generations of the family anti-exhaustion due to sexual indulgence, defying age secret recipe, in conjunction with modern scientific theory, selected natural Chinese medicinal herb develops meticulously by the theory of Chinese medical science prescription.This medicine strengthening the body resistance, tonify Qi of the kidney, Yin Yang balancing, be of illnesses and fitness, physique enhancing and bone strengthening, have resisting fatigue, defying age, hemopoietic skin care, memory reinforcing, sexual function improving effect.Compare with many life enhancement medicines on the market, its effect by force, comprehensively, reliably, lastingly.
Use Drug therapy sexual impotence of the present invention, determined curative effect, short treating period, cure rate high and more the back be difficult for recurrence, taking convenience, preparation technology are simple.Use immunocompetence, the slow down aging of all right allaying tiredness of medicine of the present invention, enhancing human body.
Medicine of the present invention is made (consumption is a weight portion) by following component:
The Radix Rhodiolae Yunnanensis 50-80 weight portion 8-22 of animal brain weight parts water 5-20 weight portion pupil urine 5-25 weight portion baby fetal hair (Crinis Carbonisatus) charcoal 3-15 weight portion Moschus 0.05-1.5 weight portion glucose 2-15 weight portion
The weight proportion scope of the formula optimization of preparation medicine of the present invention is:
The Radix Rhodiolae Yunnanensis 60-70 weight portion 10-20 of animal brain weight parts water 10-15 weight portion pupil urine 10-20 weight portion baby fetal hair (Crinis Carbonisatus) charcoal 5-10 weight portion Moschus 0.1-1 weight portion glucose 5-10 weight portion
The preferred weight proportion scope of prescription of preparation medicine of the present invention is:
The Radix Rhodiolae Yunnanensis 65-70 weight portion 15-20 of animal brain weight parts water 12-15 weight portion pupil urine 15-20 weight portion baby fetal hair (Crinis Carbonisatus) charcoal 8-10 weight portion Moschus 0.5-1 weight portion glucose 8-10 weight portion
The optimum weight proportioning of medicine of the present invention is:
Radix Rhodiolae Yunnanensis 65 weight portion animal brains 15 weight parts waters, 15 weight portion pupil urines, 15 weight portion baby fetal hair (Crinis Carbonisatus) charcoals, 8 weight portion Moschus, 0.8 weight portion glucose, 10 weight portions
Medicine of the present invention can add any acceptable accessories, makes said dosage form on any pharmaceutics.
It is clean, dry to get 50-80 weight portion Radix Rhodiolae Yunnanensis and 8-22 weight portion animal brain, pulverized the 80-100 mesh sieve, be refrigerated to-100 ℃ again--120 ℃, dehydrate again, add 3-15 weight portion baby fetal hair (Crinis Carbonisatus) charcoal, 2-15 weight portion glucose, 5-20 weight parts water and 5-25 weight portion pupil urine again, fully stirring, mixing add 0.05-1.5 weight portion Moschus and proper honey again, preparation technology according to Chinese medicine pill agent routine is prepared into honeyed pill, and every ball weighs 1 gram.
Medicine of the present invention also can be made into capsule.
Getting 50-80 weight portion Radix Rhodiolae Yunnanensis and 8-22 weight portion animal brain cleans, dry, pulverized the 80-100 mesh sieve, be refrigerated to-100 ℃ again--120 ℃, dehydrate again, add 3-15 weight portion baby fetal hair (Crinis Carbonisatus) charcoal then, 5-25 weight portion pupil urine, the water vacuum extraction, discard residue, concentrated extracting solution gets thick paste (surveying than reheating is 1.25～1.35), the thick paste of oven dry gained, add the 5-20 weight parts water after the pulverizing again, 2-15 weight portion glucose and 0.05-1.5 weight portion Moschus, abundant mixing, the preparation technology according to Chinese medicinal capsule agent routine behind the vacuum drying makes capsule.Packing, the heavy 400mg of every capsules.
Medicine of the present invention also can be made into oral liquid formulations.
It is clean, dry to get 50-80 weight portion Radix Rhodiolae Yunnanensis and 8-22 weight portion animal brain, pulverized the 80-100 mesh sieve, be refrigerated to-100 ℃ again--120 ℃, dehydrate again, add 3-15 weight portion baby fetal hair (Crinis Carbonisatus) charcoal, 5-25 weight portion pupil urine then, the water vacuum extraction discards residue, adds 5-20 weight parts water, 2-15 weight portion glucose and 0.05-1.5 weight portion Moschus again, fully stir evenly, preparation technology according to the Chinese medicine oral liquid routine makes oral liquid formulations, embedding, every 10ml.
The thinking that the present invention follows international health medicine " engineering health care medicine " designs, the defying age that is based on Radix Rhodiolae Yunnanensis, animal brain, urine of baby boys, baby's fetal hair (Crinis Carbonisatus) charcoal acts on especially, human body skin and muscle cell be can reverse and human body each big system normal function, particularly human endocrine system, reproduction, urinary system function worn out, regulate.Clinical use result shows that medicine of the present invention has following advantage:
1. medicine of the present invention can be treated sexual impotence, determined curative effect, short treating period, the high and more difficult recurrence in back of cure rate.This medicine can hypersexuality, the property eliminated detest sense.To there not being spontaneous erector, can recover spontaneous erectile ability mostly; Penis is lifted and not hard or anorthosis person during to sexual intercourse, but specificity promotes to erect; To the simultaneous phenomenon of sexual impotence, the improvement effect is arranged.
2. medicine of the present invention has the enhance immunity effect, can regulate and improve body's immunity.
3. medicine of the present invention has nootropic effect, can anti-senility, nourishing the brain and improving intelligence.
4. medicine of the present invention has the anti peroxidation of lipid ability, and tangible anti-aging effects is arranged.
5. medicine of the present invention is a pure Chinese medicinal preparation, and is through the check of Hunan Medical University sanitary system nutrition health research department, without any side effects.
Be the anti-exhaustion due to sexual indulgence that shows medicine of the present invention, antidotal beneficial effect, zoopery of the present invention and clinical data are as follows.
One, the curative effect of Drug therapy sexual impotence of the present invention treatment.
(1), clinical efficacy treatment
1 data and method
1.1 clinical data
Treatment group: 232 routine patients, 25～60 years old age, average 33.7 years old; Married average 4.9 years 1～35 year; The sexual impotence course of disease 1～10 year, average 3.5 years.
Positive controls: 120 routine patients, 22～60 years old age, average 31.7 years old; Married average 5.9 years 1～37 year; The sexual impotence course of disease 1～11 year, average 3.7 years.
1.2 diagnostic method
(1) swelling test at night (NPT): carry out with paper tape, in 3 evenings of continuous measurement, when the situation that the patient sleeps good, red, yellow, blue 3 paper tapes all fracture person are normal erection; Red, yellow, blue 3 paper tapes entirely not fracture person show not have erection night; The red paper tape that only ruptures is invalid erection; Split Huang, blue 2 paper tapes show erect insufficient.
(2) with reference to relevant diagnosis sexual impotence clinical diagnosis standard in " the clinical research guideline of new Chinese medicine treatment sexual impotence " (Ministry of Public Health was formulated in 1993).During the adult male sexual intercourse, penis can not effectively erect or erect not hard, so that in most of the cases (about chance more than 75%) can not finish sexual intercourse, continues person more than three months.
1.3 Therapeutic Method
The treatment group: give Drug therapy of the present invention, dosage form is a honeyed pill, each oral 2.Every day 2 times, took continuously 21 days.
Positive controls: GUILU BUSHEN WAN, each 6～12g, every day, 2 times (referring to one one 505～506 pages of the Pharmacopoeias of the People's Republic of China) were taken 21 days continuously.
1.4 criterion of therapeutical effect
Certainly intend criterion of therapeutical effect with reference to related content in " modernity medical science ".Clinic control: normally sexual intercourse, the objective indicator inspection is normal; Produce effects: can be interrupted and carry out normal sexual intercourse, objective indicator is obviously improved; Effectively: idol can be carried out normal sexual intercourse, and objective indicator is more preceding improvement slightly; Invalid: each index does not all have improvement before and after the medication.
2. result
Treatment group and positive controls therapeutic effect see Table 1.Clinical treatment sexual impotence the analysis showed that Drug therapy sexual impotence curative effect of the present invention is best, has stronger tonification yang invigorating functions, and is better than commercially availablely, and both have significant difference.
Table 1 treatment group and matched group curative effect be group example number clinic control produce effects enabledisable total effective rate relatively
(%) treatment organizes 232 174 32 18 8 96.6
*Positive 120 31 65 1 23 80.8 matched groups
*P＜0.05
Technical scheme of the present invention is sisters' application of applicant CN 1196258A, and medicine of the present invention has added an amount of Moschus, through treatment, finds that medicine of the present invention aspect treatment sexual impotence, has better effect than the medicine in first to file.
1.1 clinical data
Treatment group: 56 routine patients, 23～61 years old age, average 32.6 years old; Married average 5.2 years 1～34 year; The sexual impotence course of disease 1～13 year, average 4.0 years.
Positive controls: 59 routine patients, 24～59 years old age, average 30.5 years old; Married average 4.7 years 1～30 year; The sexual impotence course of disease 1～9 year, average 3.9 years.
1.2 diagnostic method
With reference to relevant diagnosis sexual impotence clinical diagnosis standard in " the clinical research guideline of new Chinese medicine treatment sexual impotence " (Ministry of Public Health was formulated in 1993).During the adult male sexual intercourse, penis can not effectively erect or erect not hard, so that in most of the cases (about chance more than 75%) can not finish sexual intercourse, continues person more than three months.
1.3 Therapeutic Method
The treatment group: give Drug therapy of the present invention, dosage form is a honeyed pill, each oral 2.Every day 2 times, took continuously 21 days.
Positive controls: give the Drug therapy of CN 1196258A, dosage form is a honeyed pill, each oral 2.Every day 2 times, took continuously 21 days.
1.4 criterion of therapeutical effect
Certainly intend criterion of therapeutical effect with reference to related content in " modernity medical science ".Clinic control: normally sexual intercourse, the objective indicator inspection is normal; Produce effects: can be interrupted and carry out normal sexual intercourse, objective indicator is obviously improved; Effectively: idol can be carried out normal sexual intercourse, and objective indicator is more preceding improvement slightly; Invalid: each index does not all have improvement before and after the medication.
2. result
Treatment group and treatment of control group effect see Table 2.Clinical treatment sexual impotence the analysis showed that Drug therapy sexual impotence curative effect of the present invention is best, has stronger tonification yang invigorating functions, and the medicine of the CN 1196258A that is better than, and both have significant difference.
Table 2 treatment group and the clinical produce effects enabledisable of matched group curative effect comparison group example number always have
Control efficiency
(%) treatment organizes 56 43 733 94.6
*Matched group 58 36 85 10 81.4
*P＜0.05
(2), to the influence of rat mating test
Treated the influence of medicine of the present invention to male Mus sexual potency animal model.
1 experiment material
1.1 medicine, reagent
The treatment group: medicine of the present invention, oral liquid formulation faces with preceding and with deionized water it is diluted to certain density test sample.
Progesterone injection: Shanghai the 9th pharmaceutical factory produces.
1.2 animal
40 of SD kind sexual maturity rats, each 20 of male and female are available from Hunan Medical University's Animal House.
2 methods and result
Get 20 female rats under pentobarbital sodium (45mg/kg) intraperitoneal anesthesia, row side ovariectomy operation again, postoperative intramuscular injection scotcil 20,000 u/kg, its 3d is with infection.Ovariectomy experimentized after 2 weeks.Before the experiment subcutaneous injection estradiol benzoate 20 μ g/ only, subcutaneous injection progesterone injection 500 μ g/ are only once more before the 4h.Get 20 male rats again and be divided into 3 groups at random, the I group gives distilled water for the blank group; II organizes positive matched group, gives the CN 1196258A medicinal liquid of 30% concentration; The III group is the treatment group, gives the medicinal liquid of the present invention of 30% concentration.Each group is all with 1ml/100g rat body weight gastric infusion; 1 time on the 1st, continuous 21d, during copulation male rat was put into 40 * 30 * 20cm cage separately 5 minutes, after it shakes down, every cage adds 1 female Mus, opening entry is fed into male Mus from female Mus and pounces on that male Mus pounces on the number of times (referring to bureau of drug administration of Ministry of Health of the People's Republic of China, " study of tcm new drug guide ") of catching female Mus in time (pounce on and catch incubation period) of catching female Mus and the 20min for the 1st time.The results are shown in Table 3, give medicine after, male Mus mating ability strengthens, and shows as to pounce on after mating to catch female Mus and shorten incubation period, pouncing on of finishing in the 20min caught number of times to be increased, and with the blank group significant difference (P＜0.05) is arranged.
Table 3 medicine of the present invention is pounced on and is caught the group concentration Mus number that influences of rat mating ability
% (only) incubation period (s) number of times blank group-10 820 ± 426.3 3.0 ± 3.8 treatments organize 30 10 397.6 ± 473.5
*23.4 ± 18.6
*N=10 compares with the blank group,
*P＜0.05
Two, medicine of the present invention is to the influence of immunity
Technical scheme of the present invention is sisters' application of applicant CN 1196258A, and medicine of the present invention has added an amount of Moschus, through treatment, finds that medicine of the present invention on the immune function of regulating body, has better effect than the medicine in first to file.
1 experiment material
1.1 medicine, reagent
The treatment group: medicine of the present invention, oral liquid formulation faces with preceding and with deionized water it is diluted to the test sample of 30% concentration.
Matched group: the medicine of CN 1196258A, oral liquid formulation faces with preceding and with deionized water it is diluted to the test sample of 30% concentration.
1.2 animal
40 of the adult white mice of Wistar are available from Hunan Medical University's Animal House.
2 methods and result
Influence to humoral immunization: stomach is raised
60The drug dilution liquid of Co irradiation mice drug dilution liquid of the present invention and CN 1196258A behind the 1ml/d administration 9d, is measured serum lysozyme (SLC) content, and result such as table 4 show that SLC has had to significantly improve (P＜0.05).
The medicine of table 4 medicine of the present invention and CN 1196258A is counted serum lysozyme content to the group concentration Mus that influences of humoral immunization
30 20 53.877 ± 12.732 treatments of (%) (only) (μ g/ml) matched group organize 30 20 105.5 ± 27.556
*N=20, P＜0.05
Three, medicine of the present invention is to the influence of rat note second power
Human senility shows as central nervous system's excitement in nervous system weakens with process of inhibition, and the cerebration ability reduces, hypomnesis.Prevent and treat brain aging with medicine, postpone and diseases such as treatment old people and alzheimer disease, come into one's own just day by day.This experimental applications 21 months old rats adopt medicine of the present invention to treat as aging model, detect the rat memory ability.
1 experiment material
1.1 medicine, reagent
The treatment group: medicine of the present invention, oral liquid formulation faces with preceding and with deionized water it is diluted to the test sample of 30% concentration, 1ml/d, continuous irrigation stomach 1 month.
Matched group: normal saline, 1ml/d, continuous irrigation stomach 1 month.
1.2 animal
The healthy SD rat, at 21 monthly ages, body weight 500g ± 100g is available from Hunan Medical University's Animal House.
2 methods and result
Utilize Y type electricity labyrinth, training method is trained routinely, and result such as table 5 show that the administration group can improve the memory ability of 21 months old rats, shorten and run to the place of safety the used time, with 21 months age groups significant difference (p＜0.05) are arranged relatively.
(X ± SD) run to the place of safety by the correct number of times accuracy of group Mus number to the influence of 21 months old rats memory abilities for table 5 medicine of the present invention
(only) (%) 10 9.000 ± 1.633 60.001 ± 10.885 11.543 ± 4.447 treatments of (s) matched group of used time organizes 9 11.571 ± 1.718
*77.143 ± 11.454
*8.127 ± 2.593
* *P＜0.05
Four, medicine of the present invention is to the active influence of several enzymes of Aged Mice
Aging is that the metabolic decline of body causes, enzyme is the metabolic key factor of control, and the generation of enzyme and active influenced will cause Metabolic disorder, thereby cause the aging of cell and body.Think that from the research of molecular biology level the old and feeble biomembranous lipid peroxidation that causes with free radical causes membrane structure damage and functionally inactive to have substantial connection.
Free radical is removed in vivo by a series of enzymes and is realized, the activity of these enzymes can be used as a kind of sign of body aging to a certain extent.(Superoxidedismulade SOD) is free radical scavenger to superoxide dismutase, extensively is present in the various tissues of body, and the SOD of geriatric animals obviously reduces.Medicine with anti-aging effects can make the growing amount of body SOD increase, and biological activity improves, thereby effectively improves the effect of removing the body free radical, delaying senility course.
Lipid peroxide is the product of free radical damage effect, so can be used as an old and feeble quantitative target.Antiaging agent can make lipid peroxide content reduce.Malonaldehyde (MDA) is the catabolite of lipid peroxide, so measure the content of MDA, can show the content of lipid peroxide indirectly, differentiates the effect of antiaging agent.
1 experiment material
1.1 medicine, reagent
Normal control group: normal saline;
The treatment group: medicine of the present invention, oral liquid formulation, and irritate the peroxidating Semen Maydis oil simultaneously;
Positive controls: peroxidating Semen Maydis oil.
1.2 animal
The Wistar white mice that grows up, 60, male and female are more than half, available from Hunan Medical University's Animal House.
2 methods and result
White mice is divided into three groups at random, and 20 every group, the normal control group is pressed 0.1ml//d; The treatment group is pressed 0.1ml//d, continuous irrigation stomach 20 days; Positive controls is pressed 0.1ml//d, continuous irrigation stomach 20 days.Separation of serum was measured serum MDA, SOD content, result such as table 6 from the abdomen arterial blood extracting in the 21st day.The result shows, oral liquid of the present invention has inhibition because of the lipid peroxide due to the peroxidating Semen Maydis oil raises, and promotes the synthetic increase effect of body SOD.Pointing out medicine of the present invention that lipid peroxide due to abnormal free radical is generated to increase has preventive effect, also has tangible anti-aging effects.
The influence that table 6 medicine of the present invention raises to lipid peroxide due to the peroxidating Semen Maydis oil
Group MDA (the nmol/L) (SOD (Nu/ml) of X ± SD) (the normal control group 6.21 ± 1.08 of X ± SD)
a199.6 ± 9.83
aTreatment group 5.18 ± 0.15
a208.66 ± 6.04
aPositive controls 9.38 ± 1.81
b192.76 ± 6.01
bN=20, three groups relatively, English alphabet difference person, P＜0.05
Following embodiment is detailed description of the present invention, is not in the present invention is limited to.
Embodiment 1
Take by weighing raw material by following proportioning:
Radix Rhodiolae Yunnanensis 60-70 gram Medulla Leporis seu Oryctolagi 10-20 gram water 10-15 gram pupil urine 10-20 gram baby fetal hair (Crinis Carbonisatus) charcoal 5-10 gram Moschus 0.1-1 gram glucose 5-10 gram
Production method is as follows:
Get 60-70 gram Radix Rhodiolae Yunnanensis and 10-20 gram Medulla Leporis seu Oryctolagi clean, dry, pulverized the 80-100 mesh sieve, be refrigerated to-120 ℃ again, dehydrate again, add 5-10 again and restrain baby's fetal hair (Crinis Carbonisatus) charcoal, 5-10 gram glucose, 10-15 gram Laoshan Spring Water and 10-20 gram pupil urine, fully stirring, mixing add 0.1-1 gram Moschus and proper honey again, preparation technology according to Chinese medicine pill agent routine is prepared into honeyed pill, and every ball weighs 6 grams.Every day secondary, each 1～2 ball.
Embodiment 2
Take by weighing raw material by following proportioning:
Radix Rhodiolae Yunnanensis 65 KEMA brains 15 gram water 15 gram pupil urines 15 gram baby fetal hair (Crinis Carbonisatus) charcoals 8 gram Moschus 0.8 gram glucose 10 grams
Production method is as follows:
It is clean, dry to get 65 gram Radix Rhodiolae Yunnanensis and 15 KEMA brains, pulverized the 80-100 mesh sieve, be refrigerated to-120 ℃ again, dehydrate again, add 8 gram baby fetal hair (Crinis Carbonisatus) charcoals, 15 gram pupil urines then, the water vacuum extraction, discard residue, concentrated extracting solution gets thick paste (surveying than reheating is 1.25～1.35), the thick paste of oven dry gained, add 15 gram Laoshan Spring Waters, 10 gram glucoses and 0.8 gram Moschus after the pulverizing again, abundant mixing, the preparation technology according to Chinese medicinal capsule agent routine behind the vacuum drying makes capsule, every 400mg, every day secondary, each 1～3.
Embodiment 3
Take by weighing raw material by following proportioning:
Radix Rhodiolae Yunnanensis 65 gram Medulla Leporis seu Oryctolagi 15 gram water 15 gram pupil urines 15 gram baby fetal hair (Crinis Carbonisatus) charcoals 8 gram Moschus 0.8 gram glucose 10 grams
Production method is as follows:
Get 65 gram Radix Rhodiolae Yunnanensis and 15 gram Medulla Leporis seu Oryctolagi clean, dry, pulverize the 80-100 mesh sieve, be refrigerated to-120 ℃ again, again dehydrate, add 8 gram baby fetal hair (Crinis Carbonisatus) charcoals, 15 gram pupil urines then, the water vacuum extraction discards residue, adds 15 gram Laoshan Spring Waters, 10 gram glucoses and 0.8 gram Moschus again, abundant mixing, add an amount of strong smelly correctives, antiseptic is made oral liquid formulations according to the preparation technology of Chinese medicine oral liquid routine, embedding, every 10ml.Every day secondary, each 10～30ml.
Because these embodiment plans are illustrating of several respects of the present invention, so the protection domain of detailed description of the present invention and requirement is not to be confined within the scope of specific embodiment disclosed herein.The embodiment of any equivalence is all within protection scope of the present invention.In fact, except here showing and describing those, by describing scope the preceding, various corrections of the present invention are clearly to this area ripe refining technical staff.These corrections also will fall within the scope of dependent claims.
Claims (27)
1. an anti-exhaustion due to sexual indulgence, antidotal pharmaceutical composition is characterized in that it is the medicament of being made by the following raw materials by weight proportions thing:
The Radix Rhodiolae Yunnanensis 50-80 weight portion 8-22 of animal brain weight parts water 5-20 weight portion pupil urine 5-25 weight portion baby fetal hair (Crinis Carbonisatus) charcoal 3-15 weight portion Moschus 0.05-1.5 weight portion glucose 2-15 weight portion
2. the described medicine of claim 1 is characterized in that it is the medicament of being made by the following weight proportion raw material:
The Radix Rhodiolae Yunnanensis 60-70 weight portion 10-20 of animal brain weight parts water 10-15 weight portion pupil urine 10-20 weight portion baby fetal hair (Crinis Carbonisatus) charcoal 5-10 weight portion Moschus 0.1-1 weight portion glucose 5-10 weight portion
3. the described medicine of claim 1 is characterized in that it is the medicament of being made by the following weight proportion raw material:
The Radix Rhodiolae Yunnanensis 65-70 weight portion 15-20 of animal brain weight parts water 12-15 weight portion pupil urine 15-20 weight portion baby fetal hair (Crinis Carbonisatus) charcoal 8-10 weight portion Moschus 0.5-1 weight portion glucose 8-10 weight portion
4. the described medicine of claim 1 is characterized in that it is the medicament of being made by the following weight proportion raw material:
Radix Rhodiolae Yunnanensis 65 weight portion animal brains 15 weight parts waters, 15 weight portion pupil urines, 15 weight portion baby fetal hair (Crinis Carbonisatus) charcoals, 8 weight portion Moschus, 0.8 weight portion glucose, 10 weight portions
5. claim 1,2,3 or 4 described medicines is characterized in that described animal brain is a horse brain.
6. claim 1,2,3 or 4 described medicines is characterized in that described animal brain is a Medulla Leporis seu Oryctolagi.
7. claim 1,2,3 or 4 described medicines is characterized in that described water is mineral water.
8. the described medicine of claim 5 is characterized in that described water is mineral water.
9. the described medicine of claim 6, its special sheet is that described water is mineral water.
10. claim 1,2,3 or 4 described anti-exhaustion due to sexual indulgence, antidotal medicine is characterized in that described medicament is a said dosage form on any pharmaceutics.
11. the described anti-exhaustion due to sexual indulgence of claim 5, antidotal medicine is characterized in that described medicament is a said dosage form on any pharmaceutics.
12. the described anti-exhaustion due to sexual indulgence of claim 6, antidotal medicine is characterized in that described medicament is a said dosage form on any pharmaceutics.
13. the described anti-exhaustion due to sexual indulgence of claim 7, antidotal medicine is characterized in that described medicament is a said dosage form on any pharmaceutics.
14. the described anti-exhaustion due to sexual indulgence of claim 8, antidotal medicine is characterized in that described medicament is a said dosage form on any pharmaceutics.
15. the described anti-exhaustion due to sexual indulgence of claim 9, antidotal medicine is characterized in that described medicament is a said dosage form on any pharmaceutics.
16. claim 1,2,3 or 4 described anti-exhaustion due to sexual indulgence, antidotal medicine is characterized in that described pharmaceutical formulation is a honeyed pill.
17. the described anti-exhaustion due to sexual indulgence of claim 5, antidotal medicine is characterized in that described pharmaceutical formulation is a honeyed pill.
18. the described anti-exhaustion due to sexual indulgence of claim 6, antidotal medicine is characterized in that described pharmaceutical formulation is a honeyed pill.
19. the described anti-exhaustion due to sexual indulgence of claim 7, antidotal medicine is characterized in that described pharmaceutical formulation is a honeyed pill.
20. the described anti-exhaustion due to sexual indulgence of claim 8, antidotal medicine is characterized in that described pharmaceutical formulation is a honeyed pill.
21. the described anti-exhaustion due to sexual indulgence of claim 9, antidotal medicine is characterized in that described pharmaceutical formulation is a honeyed pill.
22. method for preparing the pharmaceutical composition thing of claim 1, it is clean, dry to it is characterized in that getting 50-80 weight portion Radix Rhodiolae Yunnanensis and 8-22 weight portion animal brain, pulverized the 80-100 mesh sieve, be refrigerated to-100 ℃ again--120 ℃, dehydrate again, add 3-15 weight portion baby fetal hair (Crinis Carbonisatus) charcoal, 2-15 weight portion glucose, 5-20 weight parts water and 5-25 weight portion pupil urine again, abundant stirring, mixing, add 0.05-1.5 weight portion Moschus and proper honey again, be prepared into honeyed pill according to the preparation technology of Chinese medicine pill agent routine.
23. method for preparing the pharmaceutical composition thing of claim 1, it is characterized in that getting 50-80 weight portion Radix Rhodiolae Yunnanensis and 8-22 weight portion animal brain cleans, dry, pulverized the 80-100 mesh sieve, be refrigerated to-100 ℃ again--120 ℃, dehydrate again, add 3-15 weight portion baby fetal hair (Crinis Carbonisatus) charcoal then, 5-25 weight portion pupil urine, the water vacuum extraction, discard residue, concentrated extracting solution gets thick paste, and the thick paste of oven dry gained adds the 5-20 weight parts water again after the pulverizing, 2-15 weight portion glucose and 0.05-1.5 weight portion Moschus, abundant mixing, the preparation technology according to Chinese medicinal capsule agent routine behind the vacuum drying makes capsule.
24. method for preparing the pharmaceutical composition thing of claim 1, it is characterized in that getting 50-80 weight portion Radix Rhodiolae Yunnanensis and 8-22 weight portion animal brain cleans, dry, pulverized the 80-100 mesh sieve, be refrigerated to-100 ℃ again--120 ℃, dehydrate again, add 3-15 weight portion baby fetal hair (Crinis Carbonisatus) charcoal then, 5-25 weight portion pupil urine, the water vacuum extraction, discard residue, add the 5-20 weight parts water again, 2-15 weight portion glucose and 0.05-1.5 weight portion Moschus fully stir evenly, and make oral liquid formulations according to the preparation technology of Chinese medicine oral liquid routine, embedding, every 10ml.
25. the preparation method of claim 22,23 or 24 described medicines is characterized in that preferred-120 ℃ of refrigerated temperature.
26. the preparation method of claim 23 or 24 described medicines is characterized in that preferred 70 ℃-100 ℃ of the temperature of water vacuum extraction.
27. the preparation method of the described medicine of claim 23, it is characterized in that reheating said thick paste ratio, to survey be 1.25～1.35.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB991057295A CN1175828C (en) | 1999-04-13 | 1999-04-13 | Medicinal composition for relieving sexual fatigue and delaying sanility and preparing process thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB991057295A CN1175828C (en) | 1999-04-13 | 1999-04-13 | Medicinal composition for relieving sexual fatigue and delaying sanility and preparing process thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1270052A true CN1270052A (en) | 2000-10-18 |
| CN1175828C CN1175828C (en) | 2004-11-17 |
Family
ID=5272108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB991057295A Expired - Fee Related CN1175828C (en) | 1999-04-13 | 1999-04-13 | Medicinal composition for relieving sexual fatigue and delaying sanility and preparing process thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1175828C (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101485857B (en) * | 2009-02-20 | 2012-01-25 | 芜湖张恒春药业有限公司 | Chinese medicine for tonifying kidney, invigorating heart and spleen, and strengthening function of human body and preparation method thereof |
| CN105670884A (en) * | 2016-04-01 | 2016-06-15 | 王丹切 | Sexual intercourse recuperation agent |
-
1999
- 1999-04-13 CN CNB991057295A patent/CN1175828C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101485857B (en) * | 2009-02-20 | 2012-01-25 | 芜湖张恒春药业有限公司 | Chinese medicine for tonifying kidney, invigorating heart and spleen, and strengthening function of human body and preparation method thereof |
| CN105670884A (en) * | 2016-04-01 | 2016-06-15 | 王丹切 | Sexual intercourse recuperation agent |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1175828C (en) | 2004-11-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1457808A (en) | Iron scale dendrobium compound preposition and preparation and use | |
| CN1298380C (en) | Chinese traditional medicine composition with effects of activating blood circulation, dissipating blood stasis, relaxing, activating the tendons, reducing swelling and easing pain and preparation met | |
| CN1136931A (en) | Ant ginseng oral liquid and preparing process thereof | |
| CN1175828C (en) | Medicinal composition for relieving sexual fatigue and delaying sanility and preparing process thereof | |
| CN1272055C (en) | Chinese materia medica preparation of prolonging life for invigorating the kidney yang and producing method | |
| CN1150006C (en) | Beetoxin injection and its preparing process | |
| CN1183841C (en) | Anti-fatigue male's health tea its production process | |
| CN1839855A (en) | Ginsenoside F1 medicinal uses | |
| CN1488394A (en) | Chinese medicine cap sule for treating prostatic disorders | |
| CN1218714C (en) | Kidney asthenia treating medicine and its prepn process | |
| CN1305491C (en) | Chinese medicinal composition for treating irritable bowel syndrome and its preparation method | |
| WO2009115429A1 (en) | Food preparation and pharmaceutical composition containing an embryonic extract | |
| CN107737259A (en) | A kind of Chinese prescription for improving male's sexual | |
| CN1192784C (en) | Medicine prepared from extract of pubescent holly root for treating erection disfunction and preparing process thereof | |
| CN1181874C (en) | Medicine for acute cerebral hemorrhage and its preparing method | |
| CN101301379B (en) | Chinese medicinal composition and preparation and use thereof | |
| CN1723936A (en) | Traditional Chinese medicine for treating depressive disorders, and its prepn. method | |
| CN1747740A (en) | Analgesic composition | |
| CN1546143A (en) | Luyang kidney yang strengthening Chinese traditional medicinal formula and its preparation | |
| CN1931256A (en) | Chinese medicine capsule for eliminating drug addiction and its prepn process | |
| CN1063060C (en) | Compound Chinese medicine preparation for curing traumatic paraplegia and its preparation technology | |
| CN1736445A (en) | Kidney-tonifying brain-invigorating medicine and preparation process thereof | |
| CN1456217A (en) | Medicine for curing choleithiasis and preparing method thereof | |
| CN1273170C (en) | Capsule of Chinese traditional medicine for treating diseases caused by insufficiency of kidney-yang and deficiency of blood | |
| CN1099873C (en) | Application of Yanglazi in medicines, cosmetics and health-care products |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20041117 Termination date: 20150413 |
|
| EXPY | Termination of patent right or utility model |