CN1268349C - Water soluble medicament for anti inflammation, repressing bacteria, eliminating pes off smell and treating asjike, and its application - Google Patents
Water soluble medicament for anti inflammation, repressing bacteria, eliminating pes off smell and treating asjike, and its application Download PDFInfo
- Publication number
- CN1268349C CN1268349C CNB2004100977677A CN200410097767A CN1268349C CN 1268349 C CN1268349 C CN 1268349C CN B2004100977677 A CNB2004100977677 A CN B2004100977677A CN 200410097767 A CN200410097767 A CN 200410097767A CN 1268349 C CN1268349 C CN 1268349C
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- China
- Prior art keywords
- medicament
- water soluble
- beriberi
- application
- treating
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- 239000003814 drug Substances 0.000 title claims abstract description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 11
- 241000894006 Bacteria Species 0.000 title description 2
- 206010061218 Inflammation Diseases 0.000 title description 2
- 230000004054 inflammatory process Effects 0.000 title 1
- 230000000754 repressing effect Effects 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 21
- 206010047601 Vitamin B1 deficiency Diseases 0.000 claims abstract description 20
- 208000002894 beriberi Diseases 0.000 claims abstract description 20
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims abstract description 18
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims abstract description 14
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 13
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims abstract description 7
- 230000000844 anti-bacterial effect Effects 0.000 claims description 9
- 239000004327 boric acid Substances 0.000 claims description 6
- 230000003110 anti-inflammatory effect Effects 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 8
- 230000028327 secretion Effects 0.000 abstract description 8
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 7
- 210000000106 sweat gland Anatomy 0.000 abstract description 7
- 230000001954 sterilising effect Effects 0.000 abstract description 6
- 238000002360 preparation method Methods 0.000 abstract description 3
- 239000007921 spray Substances 0.000 abstract description 2
- 206010067197 Tinea manuum Diseases 0.000 abstract 1
- -1 alum Chemical compound 0.000 abstract 1
- 229940037003 alum Drugs 0.000 abstract 1
- 229960002645 boric acid Drugs 0.000 abstract 1
- 235000010338 boric acid Nutrition 0.000 abstract 1
- 235000012907 honey Nutrition 0.000 abstract 1
- 229940040145 liniment Drugs 0.000 abstract 1
- 239000000865 liniment Substances 0.000 abstract 1
- 238000005507 spraying Methods 0.000 abstract 1
- 230000009967 tasteless effect Effects 0.000 abstract 1
- 238000003756 stirring Methods 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 5
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 206010011409 Cross infection Diseases 0.000 description 3
- 206010029803 Nosocomial infection Diseases 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 230000003628 erosive effect Effects 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- 244000005700 microbiome Species 0.000 description 3
- 208000003251 Pruritus Diseases 0.000 description 2
- 230000001166 anti-perspirative effect Effects 0.000 description 2
- 239000003213 antiperspirant Substances 0.000 description 2
- 238000004332 deodorization Methods 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- VKYKSIONXSXAKP-UHFFFAOYSA-N hexamethylenetetramine Chemical compound C1N(C2)CN3CN1CN2C3 VKYKSIONXSXAKP-UHFFFAOYSA-N 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 230000002147 killing effect Effects 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000002674 ointment Substances 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 230000035900 sweating Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000003643 water by type Substances 0.000 description 2
- 239000011787 zinc oxide Substances 0.000 description 2
- TUSDEZXZIZRFGC-UHFFFAOYSA-N 1-O-galloyl-3,6-(R)-HHDP-beta-D-glucose Natural products OC1C(O2)COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC1C(O)C2OC(=O)C1=CC(O)=C(O)C(O)=C1 TUSDEZXZIZRFGC-UHFFFAOYSA-N 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 235000010206 Corchorus olitorius Nutrition 0.000 description 1
- 244000227473 Corchorus olitorius Species 0.000 description 1
- 239000001263 FEMA 3042 Substances 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- LRBQNJMCXXYXIU-PPKXGCFTSA-N Penta-digallate-beta-D-glucose Natural products OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-PPKXGCFTSA-N 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 206010048222 Xerosis Diseases 0.000 description 1
- 239000002260 anti-inflammatory agent Substances 0.000 description 1
- 230000001741 anti-phlogistic effect Effects 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 230000003750 conditioning effect Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 239000000645 desinfectant Substances 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 201000002670 dry beriberi Diseases 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 229960004011 methenamine Drugs 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 150000002898 organic sulfur compounds Chemical class 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000006748 scratching Methods 0.000 description 1
- 230000002393 scratching effect Effects 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- LRBQNJMCXXYXIU-NRMVVENXSA-N tannic acid Chemical compound OC1=C(O)C(O)=CC(C(=O)OC=2C(=C(O)C=C(C=2)C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(OC(=O)C=4C=C(O)C(O)=C(O)C=4)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(OC(=O)C=3C=C(O)C(O)=C(O)C=3)C(O)=C(O)C=2)O)=C1 LRBQNJMCXXYXIU-NRMVVENXSA-N 0.000 description 1
- 229940033123 tannic acid Drugs 0.000 description 1
- 235000015523 tannic acid Nutrition 0.000 description 1
- 229920002258 tannic acid Polymers 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 229960001296 zinc oxide Drugs 0.000 description 1
Landscapes
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The present invention relates to a preparation method of a water soluble medicament and an application thereof. The medicament is in the form of water soluble, colorless and tasteless water solution prepared from the components of boracic acid, alum, alcohol, hydrogen peroxide, honey, glycerol, acetic acid, etc. The water solution has strong functions of sterilization and bacteriostasis, and can regulate sweat gland secretion of human bodies. The medicament has a very good effect on clearing foot osmyl and treating tinea of hands and feet, particularly on rotten beriberi. The medicament can be prepared into spray or liniment for directly used on the surface of skin, and can also be applied indirectly by spraying onto leg wear and insoles.
Description
Technical field
The present invention relates to a kind of sterilization, anti-inflammation drugs.Be particularly related to a kind of sterilization, antiinflammatory, removing foot odor, treatment beriberi medicament and application thereof.
Background technology
Foot odor is very general, accounts for 1/3rd among the crowd, and in the subtropical zone, warm band area even account for more than 1/2nd of total population, though it does not belong to the disease of human body, regular meeting makes people's embarrassment in doings.Therefore remove the common aspiration that foot odor is many people.
Foot odor is the organic acid with stink that produces through microbial action of the secretions by human body sweat gland or sebaceous gland and organic sulfur compound etc., so microbial growth such as it and antibacterial, mycete, candida albicans has the effect of mutually promoting.Many people with foot odor have beriberi, and wherein particularly the erosive type beriberi is very general.
Remove foot odor at present mainly with the method for arresting sweating, antiperspirant, Western medicine has alchlor, zinc oxide, formaldehyde, hexamethylenamine, tannic acid etc., and Chinese medicine has Alumen, Corchorus olitorius L. etc.This series products has stronger convergence to skin, causes xerosis cutis, be full of cracks easily.The method of removing beriberi is a bactericidal, and dosage form has unguentum and lotion.The lotion instant effect, but big to skin irritation, now superseded substantially.Unguentum is more suitable to dry beriberi, but to erosive type, blister type beriberi, particularly has the beriberi of wound face to be not suitable for.And these two kinds of dosage forms all can not avoid on the footgear pathogenic bacteria cross infection also to ignore skin conditioning and protection simultaneously.
Summary of the invention
It is the arresting sweating antibacterial that the present invention adopts Alumen, boric acid, is antibacterial with hydrogen peroxide, acetic acid, is the skin moistening wetting agent with glycerol, Mel, do so that the ethanol hydrotropy is short, several respects comprehensive function is in skin, to permanent foot foulness eliminating, the treatment beriberi promotes skin to get well and has very good effect.This prescription is not at home and abroad seen at present as yet report.
The object of the invention is to disclose a kind of to treatment foot odor, beriberi, promotes very significant water soluble drug of the quick rehabilitation efficacy of skin and application thereof.
The present invention realizes as follows:
The percentage by weight of each component of said composition is as follows:
Alumen 3-25%
Boric acid 2-20%
Glycerol 3-25%
Ethanol 1-15%
Hydrogen peroxide 0.5-8%
Acetic acid 0.5-10%
Mel 0.5-10%
Water surplus
The present invention has studied the generation that how to prevent foot odor emphatically.As previously mentioned, prevent that the foot odor generation from mainly solving two problems: 1). suppress sweat gland secretion, particularly You Jizhi secretion; 2). killing microorganisms.Alumen has stronger convergence, and toxicity is lower, is commonly used for antiperspirant in medical treatment, also Chang Zuowei food additive use of Alumen in food service industry.In addition, according to the interrelated data record, Alumen also has certain bactericidal action and deodorization, so we act on Alumen as astringent and agent of deodorising and sterilizing; Boric acid mainly has the sterilization bacteria resistance function, is often used as disinfection drug, is mainly used to suppress the microbial growth breeding; Hydrogen peroxide, acetic acid are mainly antibacterial as sterilization.The effect of ethanol is a hydrotropy, short dried, the effect that glycerol, Mel have wet skin, lubricate the skin and muscle.
Several different disinfectants mix use in the prescription, can prevent the cross infection of antibacterial, prevent the generation of foot odor, the various microorganisms that produce beriberi also had inhibition and killing action preferably, therefore it is to beriberi, particularly the treatment of erosive type beriberi has extraordinary effect, and scratching where it itches of being caused by beriberi had significant antipruritic effect.
Because institute's with medicament is the routine disinfection agent in this prescription, and consumption so can not produce injury to human body, has good security performance in prescribed limit.
Mainly contain at present the powder or the water preparation of the preparation of Alumen or zinc oxide on the market, convergence is very strong and ignored to the maintenance of skin with to the inhibition of microorganism, uses the back that skin is easy to generate and burns.We not only have good therapeutic effect and colorless and odorless nonirritant, not injured skin to removing foot odor, beriberi.The application mode of the present invention in removing foot odor, treatment beriberi, adjusting sweat gland secretion is:
1, removing foot odor: generally use this agent 3-7 time, but about deodorization half a year to one year, generally re-use 1 and get final product for twice if any recurring.Patient's sweat gland secretion is tending towards normally, and stink disappears.Skin can not produce dry and cracked phenomenon.Product province authoritative institution detects, and goes on the market for many years, and the user has no adverse reaction.
2, treatment beriberi: this agent has very strong biocidal property, and various beriberi are all had itching-relieving action and inhibitory action preferably, and particularly to producing the beriberi of festering, therapeutic effect is very good.Because this agent has the effect of antiphlogistic healing to wound, can be sprayed on footwear, the socks again, avoid cross infection.
3, regulate sweat gland secretion, make sweat gland secretion be tending towards normal.Foot is dry and comfortable suitable.
The specific embodiment
Below be that embodiment further specifies of the present invention:
Drug prescription of the present invention is realized as follows:
Embodiment 1
Remove 100 kilograms of ionized waters, add 18 kilograms in Alumen, 13 kilograms of boric acid, heated and stirred.After the dissolving, add 10 kilograms of glycerol, 8 kilograms of 95% ethanol continue to stir, and treat that temperature is reduced to add 2 kilograms of 33% hydrogen peroxide below 40 degrees centigrade again, stir, and add 2 kilograms Mel again, stir and all practise back standing over night, packing.
Embodiment 2
Remove 100 kilograms of ionized waters, add 10 kilograms in Alumen, 6 kilograms of boric acid, heated and stirred.After the dissolving, add 15 kilograms of glycerol, 8 kilograms of 95% ethanol continue to stir, treating that temperature is reduced to adds 5 kilograms of 33% hydrogen peroxide again below 40 degrees centigrade, stir, and adds 2 kilograms Mel again, 2 kilograms of acetic acid stir and all practise the back standing over night, are divided in the spray bottle.
Claims (1)
1, a kind of antiinflammatory is antibacterial, removes the water soluble medicament of foot odor, treatment beriberi, it is characterized in that this medicament is formulated by following weight item:
(1) Alumen 3-25%
(2) boric acid 2-20%
(3) glycerol 3-25%
(4) ethanol 1-15%
(5) hydrogen peroxide 0.5-8%
(6) acetic acid 0.5-10%
(7) Mel 0.5-10%
(8) water surplus.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100977677A CN1268349C (en) | 2004-11-30 | 2004-11-30 | Water soluble medicament for anti inflammation, repressing bacteria, eliminating pes off smell and treating asjike, and its application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100977677A CN1268349C (en) | 2004-11-30 | 2004-11-30 | Water soluble medicament for anti inflammation, repressing bacteria, eliminating pes off smell and treating asjike, and its application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1650892A CN1650892A (en) | 2005-08-10 |
| CN1268349C true CN1268349C (en) | 2006-08-09 |
Family
ID=34869488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2004100977677A Expired - Fee Related CN1268349C (en) | 2004-11-30 | 2004-11-30 | Water soluble medicament for anti inflammation, repressing bacteria, eliminating pes off smell and treating asjike, and its application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1268349C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101416987B (en) * | 2008-03-19 | 2011-06-22 | 朱光勇 | Honey acid mixture, preparation and application thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU187614U1 (en) * | 2018-07-30 | 2019-03-13 | Николай Иванович Мамаев | MULTILAYER ANTIBACTERIAL FOOTWEAR INsole |
-
2004
- 2004-11-30 CN CNB2004100977677A patent/CN1268349C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101416987B (en) * | 2008-03-19 | 2011-06-22 | 朱光勇 | Honey acid mixture, preparation and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1650892A (en) | 2005-08-10 |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
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| CF01 | Termination of patent right due to non-payment of annual fee |