CN1183934C - Disinfectant - Google Patents
Disinfectant Download PDFInfo
- Publication number
- CN1183934C CN1183934C CN 02113331 CN02113331A CN1183934C CN 1183934 C CN1183934 C CN 1183934C CN 02113331 CN02113331 CN 02113331 CN 02113331 A CN02113331 A CN 02113331A CN 1183934 C CN1183934 C CN 1183934C
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- CN
- China
- Prior art keywords
- concentration
- iodine
- medicine
- benzoic acid
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000000645 desinfectant Substances 0.000 title 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 claims abstract description 30
- YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims abstract description 30
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 29
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims abstract description 15
- 239000005711 Benzoic acid Substances 0.000 claims abstract description 15
- 235000010233 benzoic acid Nutrition 0.000 claims abstract description 15
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims abstract description 15
- 229960004889 salicylic acid Drugs 0.000 claims abstract description 15
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 claims abstract description 12
- 239000003814 drug Substances 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 9
- 238000000034 method Methods 0.000 claims abstract description 7
- 241000221079 Euphorbia <genus> Species 0.000 claims description 15
- 230000000844 anti-bacterial effect Effects 0.000 claims description 15
- 239000003899 bactericide agent Substances 0.000 claims description 13
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 9
- 229910052740 iodine Inorganic materials 0.000 claims description 9
- 239000011630 iodine Substances 0.000 claims description 9
- 239000000706 filtrate Substances 0.000 claims description 8
- 239000000843 powder Substances 0.000 claims description 8
- DKNPRRRKHAEUMW-UHFFFAOYSA-N Iodine aqueous Chemical compound [K+].I[I-]I DKNPRRRKHAEUMW-UHFFFAOYSA-N 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 7
- 239000000758 substrate Substances 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 5
- 238000004140 cleaning Methods 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 claims 2
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 16
- 230000001954 sterilising effect Effects 0.000 abstract description 15
- 230000000694 effects Effects 0.000 abstract description 12
- 208000003251 Pruritus Diseases 0.000 abstract description 5
- 230000002159 abnormal effect Effects 0.000 abstract description 3
- 230000007803 itching Effects 0.000 abstract description 3
- 229920000832 Cutin Polymers 0.000 abstract description 2
- 231100000957 no side effect Toxicity 0.000 abstract description 2
- 241000894006 Bacteria Species 0.000 abstract 2
- REPVLJRCJUVQFA-UHFFFAOYSA-N (-)-isopinocampheol Natural products C1C(O)C(C)C2C(C)(C)C1C2 REPVLJRCJUVQFA-UHFFFAOYSA-N 0.000 abstract 1
- MFYSUUPKMDJYPF-UHFFFAOYSA-N 2-[(4-methyl-2-nitrophenyl)diazenyl]-3-oxo-n-phenylbutanamide Chemical compound C=1C=CC=CC=1NC(=O)C(C(=O)C)N=NC1=CC=C(C)C=C1[N+]([O-])=O MFYSUUPKMDJYPF-UHFFFAOYSA-N 0.000 abstract 1
- 240000000225 Euphorbia hirta Species 0.000 abstract 1
- 241000219784 Sophora Species 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 229960004365 benzoic acid Drugs 0.000 abstract 1
- 229940116229 borneol Drugs 0.000 abstract 1
- CKDOCTFBFTVPSN-UHFFFAOYSA-N borneol Natural products C1CC2(C)C(C)CC1C2(C)C CKDOCTFBFTVPSN-UHFFFAOYSA-N 0.000 abstract 1
- 238000005536 corrosion prevention Methods 0.000 abstract 1
- DTGKSKDOIYIVQL-UHFFFAOYSA-N dl-isoborneol Natural products C1CC2(C)C(O)CC1C2(C)C DTGKSKDOIYIVQL-UHFFFAOYSA-N 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 230000035611 feeding Effects 0.000 abstract 1
- 230000036074 healthy skin Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 231100000956 nontoxicity Toxicity 0.000 abstract 1
- 229960004839 potassium iodide Drugs 0.000 abstract 1
- 230000035900 sweating Effects 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 9
- 201000004647 tinea pedis Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 208000024891 symptom Diseases 0.000 description 5
- 239000000796 flavoring agent Substances 0.000 description 4
- 235000019634 flavors Nutrition 0.000 description 4
- 238000005303 weighing Methods 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 230000001225 therapeutic effect Effects 0.000 description 3
- 102000011782 Keratins Human genes 0.000 description 2
- 108010076876 Keratins Proteins 0.000 description 2
- 208000002474 Tinea Diseases 0.000 description 2
- 241000130764 Tinea Species 0.000 description 2
- 244000052616 bacterial pathogen Species 0.000 description 2
- 210000002683 foot Anatomy 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- -1 soak after 5-7 days Substances 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 206010011409 Cross infection Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010029803 Nosocomial infection Diseases 0.000 description 1
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- NDAUXUAQIAJITI-UHFFFAOYSA-N albuterol Chemical compound CC(C)(C)NCC(O)C1=CC=C(O)C(CO)=C1 NDAUXUAQIAJITI-UHFFFAOYSA-N 0.000 description 1
- 230000001139 anti-pruritic effect Effects 0.000 description 1
- 239000003908 antipruritic agent Substances 0.000 description 1
- 208000002894 beriberi Diseases 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000004332 deodorization Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- 108010084652 homeobox protein PITX1 Proteins 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004089 microcirculation Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 229940070384 ventolin Drugs 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention provides medicine for killing bacteria, which is prepared from the following raw material: euphorbia hirta, lightyellow sophora root, iodine, potassium iodide, benzoic acid, salicylic acid, borneol and medical alcohol. A method of modern medicine and pharmacology is adopted on the basis of traditional medicine achievements so as to achieve the purposes of sterilization, corrosion prevention, dampness removal, itching relief, sweating inhibition and abnormal foot smell elimination. Cutin in sole skin is dissolved or softened so that accumulated bacterium-carrying skin surfaces on soles automatically desquamate, and new deep healthy skin rapidly grows completely. Restored skin is smooth and fine, people do not have adverse feedings in the entire process, and the present invention has no influence on walking and normal life. With the advantages of no toxicity, no side effect, convenient use, high stability, rapid curative effect and high cure rate of more than 90%, the medicine is ideal medicine for killing bacteria.
Description
The present invention relates to a kind of bactericide, the especially a kind of Dakin solution that can kill pathogenic bacterium such as fungus.
Beriberi that tinea pedis promptly is commonly called as or tinea pedis, it is because of pathogenic fungus infects due to the pedal skin, and is the most common in tinea.Because this sick cardinal symptom is very to itch incomparably, regular meeting makes the patient go to scratch the affected part with hands, and pathomycete infects the source of infection that finger forms other positions of health; Besides also can be infected when the articles for daily uses such as the used slippers of contact tinea patient, towel, bathtubs, therefore, the tinea pedis disease is again a kind of infectious disease.Though it is multiple that the medicine of existing treatment tinea pedis disease has, but still can not eliminate this transmission of disease, therefore, be necessary prior art is improved.
The object of the present invention is to provide a kind of have sterilization, sterilization, deodorization, antipruritic and can soften vola portion cutin, eliminate the bactericide of foot abnormal flavour.
Bactericide provided by the invention is made up of the raw material of following weight portion:
Garden euphorbia herb 150-300 part,
Radix Sophorae Flavescentis 100-250 part,
Iodine 1-5 part,
Potassium iodide 1-5 part,
Benzoic acid 10-20 part,
Salicylic acid 10-20 part,
Borneolum Syntheticum 10-20 part,
Ethanol is an amount of.
The wherein little suffering of its nature and flavor of garden euphorbia herb, acid, little cold has heat-clearing and toxic substances removing, the effect of convergence itching relieving.
Its nature and flavor bitter cold of Radix Sophorae Flavescentis has the effect of heat clearing and damp drying, wind dispelling insecticide.Iodine has the effect of sterilization antiseptical, allocates the potassium iodide hydrotropy into, and its concentration is 0.1-0.5%.It is anticorrosion that salicylic acid has sterilization, the effect of dissolving skin keratin, and its concentration is 1-2%.Benzoic acid has the effect of sterilization antiseptical, and its concentration is 1-2%.Borneolum Syntheticum concentration is 1-2%.Percentage ratio of the present invention all is weight percentage.
Method for production of the present invention is: get above-mentioned garden euphorbia herb and Radix Sophorae Flavescentis, after cleaning is dried, be ground into powder, adding concentration is 75% medical ethanol, soaks 5-7 days, and it is standby to extract filtrate.In filtrate, add iodine and potassium iodide again, make the concentration of iodine reach 0.1-0.5%, and add salicylic acid, benzoic acid and Borneolum Syntheticum, make their concentration reach 1-2%, fully promptly get the medicinal liquid that sterilizes behind the mixing, it is sprayed on the affected part or is sprayed at the effect that can play disinfection in the footwear.
Other method of the present invention is: get above-mentioned garden euphorbia herb and Radix Sophorae Flavescentis, after cleaning is dried, be ground into powder, it is an amount of to add concentration and be 75% medical ethanol, add the iodine solution that concentration is 0.1-0.5% again, after concentration is salicylic acid, benzoic acid and the Borneolum Syntheticum solution of 1-2%, promptly get the mass that sterilizes with soft substrate mixing.This mass is coated in socks inner bottom part and side bottom, gets final product.Described soft substrate is the soft substrate based on medical ventolin.
The clinical use result of bactericide provided by the invention shows to have following advantage and effect:
1, it is on the basis of traditional medicine achievement, dissolved in the method for modern medicine and pharmacology, blending the east and the west, reach sterilization and anticorrosion, removing damp to relieve itching, the convergence hidroschesis, eliminate the foot abnormal flavour, dissolving or softening vola portion skin keratin improve the pedal skin microcirculation, activate immunity of organism, recover the normal effect of pedal skin;
2, use this medicine back foot part old skin surface that carries disease germs to come off naturally, the newborn epidermis ramp of its deep health is complete, and the skin after recovering is bright and clean satiny, and whole process does not have bad sensation, can not influence walking and normal life:
3, this medicine no side effects is easy to use, good stability, and its curative effect is fast, and cure rate reaches more than 90%.
Therefore, the present invention is a kind of comparatively ideal bactericide.
Be the bactericide that shows the present invention therapeutic effect to the tinea pedis disease, the present invention is through the clinical observation of 100 many cases systems, and select medical history, the state of an illness, age, different tinea pedis patient's 76 examples of sex and carry out clinical observation, 20-30 year patient 22 people wherein, 35-50 year patient 38 people, 55-65 year patient 16 people.
Its clinical symptoms shows as: 1, vesicle; 2, decortication; 3, very itch incomparably.
According to patient's oral account symptom and clinical symptoms, determine conditions of patients, formulate following therapeutic scheme according to each patient's the state of an illness respectively again:
Patients with mild is worn socks 1-3 days that are coated with this sterilization mass, and is promptly effective.
The patient with severe symptoms except that wearing the socks that are coated with this sterilization mass, also needs the sterilization medicinal liquid in affected part spraying the present invention, and the inner surface at wearing shoes sprays the sterilization medicinal liquid simultaneously, and 1-2 days take effect, and its effect is more obvious.
Criterion of therapeutical effect is as follows:
Complete: no longer include blister, no longer decortication, no scratchiness, and the skin surface that newly grows is comparatively bright and clean satiny.
Take a turn for the better: no longer include blister, no longer decortication, but scratchiness is arranged once in a while, the skin surface that newly grows is smooth.
After above-mentioned 76 routine tinea pedis patients being carried out 1-3 days treatment, have 70 people all to cure, 4 people take a turn for the better, and 2 people disease occurs once more because of cross infection, but after the continuous treatment through a week, no longer recurrence.
Embodiment 1
Earlier take by weighing garden euphorbia herb and the Radix Sophorae Flavescentis raw material of making powder: garden euphorbia herb 150 grams by following proportioning, Radix Sophorae Flavescentis 250 grams, adding concentration and be 75% medical ethanol makes it soak raw material, soak after 5-7 days, extract filtrate, in this filtrate, add each 5 gram of iodine and potassium iodide then, each 20 gram of salicylic acid and benzoic acid and Borneolum Syntheticum, add concentration again and be 75% medical ethanol to 1000ml, get 1000ml sterilization medicinal liquid after fully being mixed, wherein the concentration of iodine is 0.5%, and the concentration of salicylic acid and benzoic acid and Borneolum Syntheticum respectively is 2% gram.
Embodiment 2
Take by weighing garden euphorbia herb and the Radix Sophorae Flavescentis raw material of making powder by following proportioning: garden euphorbia herb 300 grams, Radix Sophorae Flavescentis 100 grams, adding concentration and be 75% medical ethanol makes it soak raw material, soak after 5-7 days, extract filtrate, in this filtrate, add each 1 gram of iodine and potassium iodide then, each 15 gram of salicylic acid and benzoic acid and Borneolum Syntheticum, add concentration again and be 75% medical ethanol to 1000ml, get 1000ml sterilization medicinal liquid after fully being mixed, wherein the concentration of iodine is 0.1%, and the concentration of salicylic acid, benzoic acid and Borneolum Syntheticum respectively is 1.5%.
Embodiment 3
Take by weighing garden euphorbia herb and the Radix Sophorae Flavescentis raw material of making powder by following proportioning: garden euphorbia herb 200 grams, Radix Sophorae Flavescentis 150 grams, it is an amount of to add concentration and be 75% medical ethanol, each 3 gram of iodine and potassium iodide, each 20 gram of salicylic acid, Borneolum Syntheticum and benzoic acid, add medical soft substrate and medical ethanol furnishing 1000 gram sterilization masses again, it is coated in socks inner bottom part and side bottom, promptly become Bactericidal socks.
Embodiment 4
Take by weighing garden euphorbia herb and the Radix Sophorae Flavescentis raw material of making powder by following proportioning: garden euphorbia herb 200 grams, Radix Sophorae Flavescentis 200 grams, it is an amount of to add concentration and be 75% medical ethanol, each 4 gram of iodine and potassium iodide, each 10 gram of salicylic acid, Borneolum Syntheticum and benzoic acid, add medical soft substrate and medical ethanol furnishing 1000 gram sterilization masses again, it is coated in socks inner bottom part and side bottom, promptly become Bactericidal socks.
Claims (4)
1, a kind of bactericide is characterized in that it is made by the raw material of following weight portion:
Garden euphorbia herb 150-300 part,
Radix Sophorae Flavescentis 100-250 part,
Iodine 1-5 part,
Potassium iodide 1-5 part,
Benzoic acid 10-20 part,
Salicylic acid 10-20 part,
Borneolum Syntheticum 10-20 part,
Ethanol is an amount of.
2, bactericide according to claim 1 is characterized in that the concentration of iodine and potassium iodide is 0.1-0.5% in the medicine, and the concentration of salicylic acid, benzoic acid and Borneolum Syntheticum is 1-2%.
3, the preparation method of bactericide according to claim 1 is characterized in that the medicinal liquid of described bactericide makes by following method: get garden euphorbia herb and Radix Sophorae Flavescentis, after cleaning is dried, be ground into powder, adding concentration is 75% medical ethanol, soaks 5-7 days, and it is standby to extract filtrate; In filtrate, add iodine and potassium iodide again, make the concentration of iodine reach 0.1-0.5%, and add salicylic acid, benzoic acid and Borneolum Syntheticum, make their concentration reach 1-2%, fully promptly get the medicinal liquid that sterilizes behind the mixing.
4, the preparation method of bactericide according to claim 1, the mass that it is characterized in that described bactericide makes by following method: get garden euphorbia herb and Radix Sophorae Flavescentis, after cleaning is dried, be ground into powder, it is an amount of to add concentration and be 75% medical ethanol, add the iodine solution that concentration is 0.1-0.5% again, after concentration is salicylic acid, benzoic acid and the Borneolum Syntheticum solution of 1-2%, promptly get the mass that sterilizes with soft substrate mixing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02113331 CN1183934C (en) | 2002-02-03 | 2002-02-03 | Disinfectant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02113331 CN1183934C (en) | 2002-02-03 | 2002-02-03 | Disinfectant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1436557A CN1436557A (en) | 2003-08-20 |
| CN1183934C true CN1183934C (en) | 2005-01-12 |
Family
ID=27628408
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02113331 Expired - Fee Related CN1183934C (en) | 2002-02-03 | 2002-02-03 | Disinfectant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1183934C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810198A (en) * | 2010-05-06 | 2010-08-25 | 佛山市正典生物技术有限公司 | Salicylic acid-iodine disinfector and preparation method thereof |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100344292C (en) * | 2005-01-21 | 2007-10-24 | 张拴成 | Injection for treating facial tic |
| CN100415100C (en) * | 2006-07-06 | 2008-09-03 | 王德昌 | Active disinfectant germicide and method for preparing same |
| CN101947253B (en) * | 2010-09-29 | 2011-09-28 | 哈尔滨乐泰药业有限公司 | External compound preparation for curing tinea corporis as well as preparation method and content measuring method thereof |
| CN103301189B (en) * | 2013-06-09 | 2016-01-20 | 万强胜 | A kind of medicine for the treatment of tinea capitis |
| CN106309544A (en) * | 2015-06-24 | 2017-01-11 | 赵耀芳 | Chinese and Western medicine composition used for treating erosive beriberi and preparation method thereof |
| CN107513014A (en) * | 2016-06-17 | 2017-12-26 | 佛山市正典生物技术有限公司 | A kind of salicylic acid-iodine complex compound, preparation method and application |
-
2002
- 2002-02-03 CN CN 02113331 patent/CN1183934C/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810198A (en) * | 2010-05-06 | 2010-08-25 | 佛山市正典生物技术有限公司 | Salicylic acid-iodine disinfector and preparation method thereof |
| CN101810198B (en) * | 2010-05-06 | 2015-01-28 | 佛山市正典生物技术有限公司 | Salicylic acid-iodine disinfector and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1436557A (en) | 2003-08-20 |
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