CN1264586A - Compound Chinese medicine for treating hepatocholepathy - Google Patents

Abstract

A compound Chinse medicine for treating hepatocholepathy is prepared from 18 Chinese-medicinal materials including bear gall powder, honersuckle flower, forsythia fruit, isatis root, astragalus root, etc. Its advantages are high curative effect and low toxic by-effect.

Description

The compound Chinese medicinal preparation of treatment liver-gallbladder disease

The present invention relates to a kind of compound Chinese medicinal preparation for the treatment of liver-gallbladder disease.

Liver-gallbladder disease is China and worldwide high morbidity, particularly its harm of hepatitis B (abbreviation hepatitis B) is very serious, mention hepatitis B, the somebody just associates liver cirrhosis-hepatic ascites-hepatocarcinoma trilogy, hepatitis B is just as being hidden in the intravital time bomb of people, all the time all threatening human life, show according to World Health Organization's investigation, China is the hepatitis B virus district occurred frequently, add up according to the authoritative sources again, the present hepatitis B virus carriers of China has 1.2 hundred million people approximately, annual number of the infected is about 9,000,000, and the annual number because of hepatopathy death in the whole nation is up to about 300,000, and the 50%th, former shape hepatocarcinoma, these Patients with Primary overwhelming majority causes by infecting hepatitis B virus, so medical circle will treat the hepatitis B conduct project of capturing always and be studied.

Existing medicine is based on interferon, liver-protecting tablet; reach bifendate, hepatitis spirit etc.; interferon can reach about 30% to the total effective rate of hepatitis B; but there is most patient to play interference and have very big side effect; as cold like symptoms (vomiting, feel sick, headache, fever etc.), the Main Ingredients and Appearance of liver-protecting tablet is a Radix Salviae Miltiorrhizae, and the liver protecting is arranged; promote the effect of liver blood circulation, but not high to the hepatitis B virus converting negative rate.Next bifendate transaminase lowering; its active ingredient is a Fructus Schisandrae Chinensis; its clinical trial confirms; this medical instrument protects the liver; the function of anti-infringement and enhancing liver detoxification; can reach about 80% to the effective percentage that reduces glutamate pyruvate transaminase; but knock-on can appear in a few patients in drug withdrawal or medication process; little to hepatitis B virus lethality, hepatitis spirit Main Ingredients and Appearance is a Radix Sophorae Tonkinensis, and the hepatocellular effect of protection is arranged; alleviate toxicant to hepatocellular infringement; reduce glutamate pyruvate transaminase, hepatitis B virus is had certain inhibitory action, to a little less than the hepatitis B virus lethality and have little toxicity.

The purpose of this invention is to provide a kind of compound Chinese medicinal preparation that the treatment liver-gallbladder disease is had better curative effect.

Goal of the invention of the present invention is achieved through the following technical solutions: the composition of raw materials of this medicine: Cordyceps 5-50g, Stigma Croci 5-50g, Fel Ursi powder 20-100g, Fructus Schisandrae Chinensis 10-100g, Radix Astragali 10-100g, Carapax Trionycis 10-100g, Squama Manis 10-100g, Flos Lonicerae 20-100g, Fructus Forsythiae 20-100g, Radix Isatidis 20-100g, Rhizoma Alismatis 20-100g, Semen Coicis 30-100g, Endothelium Corneum Gigeriae Galli 10-100g, Fructus Crataegi 15-100g, Fructus Lycii 10-100g, Radix Salviae Miltiorrhizae 60-100g, Radix Curcumae 20-1000g, Semen Arecae 10-100g, Rhizoma Corydalis 10-100g.

Liver and gall diseases is clinical common, wherein changes into slow shape and delays that difficult more the person is also numerous, and in the last few years, the present invention achieved notable results in a large amount of clinical research practices, had accumulated extremely valuable observation of curative effect data.

In order to carry forward the speciality of motherland's medical science, the advantage of performance traditional Chinese medical science traditional remedies is promoted achievement in research.

It is considered herein that liver-gallbladder disease mostly to be damp and hot poison and in invade, liver and gall incoordination between the spleen and stomach, qi depression to blood stasis, yang blood and qi loss, positive in a word deficiency of vital energy institute extremely, the institute of heresy, its gas must void.The present invention uses Fel Ursi powder, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis heat-clearing and toxic substances removing to be monarch, and they all kill and wound first, second, hepatitis C virus effect in modern medicine.With strengthening the body resistance such as the Radix Astragali, Cordyceps, Fructus Schisandrae Chinensis, Fructus Lycii is minister, and above-mentioned all medicines can be pounced on qi and blood invigorating, and modern pharmacology enhancing human body immunity power suppresses the virus replication effect.Carapax Trionycis, Stigma Croci, Radix Salviae Miltiorrhizae, Endothelium Corneum Gigeriae Galli have the spleen and stomach regulating in the side, digestion-promoting spleen-invigorating, invigorate blood circulation, blood stasis removing, the function of hard masses softening and resolving, after all medicines cooperated, the effect of playing the soft liver spleen that contracts altogether was assistant, help again with Radix Curcumae, bulky liver-smoothing, qi-regulating parasite killing, Rhizoma Alismatis, Semen Coicis, the pain relieving of rhizoma corydalis diuretic, Squama Manis blood stasis removing eliminating stagnation specially can be manageed it and be loose, the meridian dredging reaches disease and does and make.

Play heat-clearing and toxic substances removing, strengthening the body resistance altogether, hard masses softening and resolving, the pain relieving of liver-smoothing, qi-regulating diuretic attack effect.

Medicine of the present invention carries out pharmacology test through Heilongjiang University of Chinese Medicine, and its experiment account is bright, and this medicine has no side effect.Carried out clinical treatment in units such as Heilongjiang Province out-patient department of the association of traditional Chinese medicine, institutes of Chinese materia medica, east, Harbin City.

Clinical case is that 1085 its curative effect situations of example see the following form:

The example number	Recovery from illness	Produce effects	Effectively	Invalid	Total effective rate
						1085	??869	??114	??47	??55
??80.1％	??10.5％	??4.33％	??5.07％	????94.93％

Prove by above clinical report, the present invention compares its cure rate and all improves a lot with its every index extremely with interferon etc., and can not have side effects and damage other organ of human body, avirulence of the present invention, its property of medicine is stable not only can be removed the ailing of patient but also guarantee that the patient is without fear of an attack from the rear, safe in utilization, reliable, the present invention compares comparatively economical with existing medicine, be fit to apply.

Below in conjunction with example the present invention is further commented embodiment 1: to the drug ratio of first, second, hepatitis C virus:

Cordyceps 20g Stigma Croci 10g Fel Ursi powder 20g Fructus Schisandrae Chinensis 80g

Radix Astragali 80g Radix Isatidis 80g Rhizoma Alismatis 20g Semen Coicis 30g

Endothelium Corneum Gigeriae Galli 20g Fructus Crataegi 30g Fructus Lycii 50g Radix Salviae Miltiorrhizae 100g

Radix Curcumae 20g Semen Arecae sheet 20g Rhizoma Corydalis 20g Squama Manis 10g

Carapax Trionycis 20g.

Fructus Lycii, the Radix Astragali, Cordyceps can increase body immunity, suppress virus replication, and Stigma Croci plays the effect of activating blood circulation to dissipate blood stasis, Radix Isatidis kills and wounds virus,, Fructus Schisandrae Chinensis, Radix Salviae Miltiorrhizae transaminase lowering, the Fel Ursi powder increase ability of killing the virus, Rhizoma Alismatis, the kidney invigorating of Semen Coicis diuretic.

Supply raw materials according to above-mentioned proportioning raw materials and to prepare:

Pulverize a Squama Manis, the husky back of scalding of Carapax Trionycis

All the other medicines are pulverized, are sieved more than 100 orders except b Cordyceps, Stigma Croci, Fel Ursi powder, Squama Manis, the Carapax Trionycis

C Cordyceps, Stigma Croci, Fel Ursi powder sieve more than 100 orders with a small amount of medicated powder mixing facing-up, and the back is general with other medicated powder blending water to be ball, normal temperature drying, polishing

The d packing.

Embodiment 2: to the drug ratio of liver cirrhosis, ascites:

Cordyceps 50g Stigma Croci 50g Fel Ursi powder 50g Fructus Schisandrae Chinensis 50g

Radix Astragali 100g Radix Isatidis 50g Rhizoma Alismatis 100g Semen Coicis 100g

Endothelium Corneum Gigeriae Galli 80g Fructus Crataegi 100g Fructus Lycii 50g Radix Salviae Miltiorrhizae 100g

Radix Curcumae 20g Semen Arecae sheet 30g Rhizoma Corydalis 40g Squama Manis 80g Carapax Trionycis 100g.

Cordyceps, the Radix Astragali, Endothelium Corneum Gigeriae Galli make liver cell regeneration, the Squama Manis softening the hard mass, loose and to separate Rhizoma Alismatis invigorating kidney to promote diuresis, Rhizoma Corydalis pain relieving, Carapax Trionycis YIN nourishing, diuretic.

The compound method of present embodiment is identical with embodiment 1, no longer repeats here.

Embodiment 3: to the drug ratio of cholecystitis, calculus:

Cordyceps 10g Stigma Croci 10g Fel Ursi powder 100g Fructus Schisandrae Chinensis 20g

Radix Astragali 20g Radix Isatidis 100g Rhizoma Alismatis 20g Semen Coicis 30g

Endothelium Corneum Gigeriae Galli 10g Fructus Crataegi 15g Fructus Lycii 10g Radix Salviae Miltiorrhizae 60g

Radix Curcumae 10g Semen Arecae sheet 10g Rhizoma Corydalis 30g Squama Manis 20g

Carapax Trionycis 40g.

Carapax Trionycis has the softening the hard mass effect, and Fel Ursi powder has the antiinflammatory fossilization.

The compound method of present embodiment is identical with embodiment 1, no longer repeats here.

Claims (1)

1, a kind of compound Chinese medicinal preparation for the treatment of liver-gallbladder disease, it is characterized in that: the composition of raw materials of this medicine is: Cordyceps 5-50g, Stigma Croci 5-50g, Fel Ursi powder 20-100g, Fructus Schisandrae Chinensis 10-100g, Radix Astragali 10-100g, Carapax Trionycis 10-100g, Squama Manis 10-100g, Flos Lonicerae 20-100g, Fructus Forsythiae 20-100g, Radix Isatidis 20-100g, Rhizoma Alismatis 20-100g, Semen Coicis 30-100g, Endothelium Corneum Gigeriae Galli 10-100g, Fructus Crataegi 15-100g, Fructus Lycii 10-100g, Radix Salviae Miltiorrhizae 60-100g, Radix Curcumae 20-1000g, Semen Arecae 10-100g, Rhizoma Corydalis 10-100g.