CN1086949C - Chinese medicine for hepatitis B and its preparation - Google Patents

Abstract

The present invention discloses a medicine for treating hepatitis B, which uses multiple Chinese medicines, such as pseudostellaria roots, astragalus roots, radix scutellariae, radix sophorae flavescentis, bupleurum roots, artemisiae scopariae, barbat skullcap, asket fern, bittersweet herbs, flaccid aster herbs, etc., as raw materials. The Chinese medicines are respectively dried and ground, then prepared in a proportion based on Chinese medicine theories and prescriptions, and then made into powder or blocks by maturing and sterilization. The present invention has the advantages of unique prescription and obvious therapeutic efficacy.

Description

Chinese medicine of treatment hepatitis B and preparation method thereof

The present invention relates to a kind of medicine for the treatment of hepatitis B, is the Chinese patent medicine of feedstock production with the Chinese herbal medicine specifically, the invention still further relates to the preparation method of this medicine.

Hepatitis B is serious threat human life's a common frdquently encountered disease, hepatitis B patient has surpassed several hundred million people in the world at present, and China is near 100,000,000 2 thousand ten thousand people, and this sick sickness rate is very high, case fatality rate is higher than malignant tumor, is one of world medicine three big pertinacious diseases that seriously jeopardize the human life.

Chronic viral hepatitis B cannot be cured all one's life, and complication extensively and seriously owing to the long-term existence of hepatitis B virus in the blood, can cause the grievous injury of various organs in the body, and can bring out liver cirrhosis, hepatic ascites, hepatocarcinoma, be the common cause of death of hepatitis B virus patient.

The domestic and international at present treatment to primary disease runs into following thorny problem:

If 1, the relatively effective drug main interference element of anti-hepatitis virus, but that the interference element is controlled the hepatitis B side effect is big, curative effect is low, life-time service, and granulocytopenia, thrombocytopenia and anemia can take place in the patient.

2, present both at home and abroad treatment hepatitis B adopts the means of western medicine mostly, but Western medicine costs an arm and a leg, and toxic and side effects is big, discretely also can cause the reaction of reversibility neurotoxicity.

Though 3, the domestic Chinese patent medicine that a lot of treatment hepatitis B are arranged, curative effect is all satisfied not to the utmost, and the viral index in treatment back can not be turned out cloudy fully.

To provide a kind of anti-hepatitis virus good effect in of the present invention day, can improve the liver blood circulation, the therapeutic agent of cheap, the treatment hepatitis B that has no side effect.

Another object of the present invention provides the preparation method of this treating hepatitis B agent.

The object of the present invention is achieved like this:

Acute and chronic hepatitis B belongs to " jaundice " disease categories such as " costalgias " at tcm internal medicine, and its etiology and pathogenesis is main relevant with damp and hot heresy, damp and hot invasion, and strongly fragrant heat-transformation of a specified duration, " opinion pathogenesis " two heat must wet and more vehement, hotly and more horizontal wet, and damp and hot two close, and it is seriously ill and fast.Damp and hot more Sheng, poison helps heat to invade liver blood, and virus is flourishing in the blood, and venation block is viral hepatitis B.

Technical solution of the present invention is based on motherland's medical science to pathogenetic understanding of hepatitis B and Therapeutic Principle, filtering out from ancestral's medical treasure-house can clearing away heat-damp and promoting diuresis, make damp and hot two minutes, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, improve the liver blood circulation, strengthening vital QI to eliminate pathogenic factors stops hepatic necrosis, promotes liver cell regeneration, can suppress to remove hepatitis B virus in the body, make the normal natural edible-plant medicine of liver function recovery,, select medicine formulated meticulously by the theory of Chinese medical science prescription.

Medicine of the present invention is made (consumption is a weight portion) by following level part.

Radix Pseudostellariae 5-10 part Radix Astragali 20-30 part Radix Scutellariae 20-30 part

Radix Sophorae Flavescentis 10-20 part Rhizoma Polygoni Cuspidati 20-30 part Radix Salviae Miltiorrhizae 20-30 part

Herba Hyperici Japonici 10-20 part Radix Bupleuri 20-30 part Herba Artemisiae Scopariae 20-30 part

Muskmelon pedicel 5-10 part Herba Asteris Flaccidi 10-20 part Herba Solani Nigri 10-20 part

Rhizoma Picrorhizae 20-30 part Folium Aloe 10-20 part Herba Solani Lyrati 10-20 part

Nidus Vespae 5-10 part Herba Scutellariae Barbatae 20-30 part Rhizoma Osmundae 5-10 part

Folium Isatidis 20-30 part Radix Glycyrrhizae 10-30 part Herba Andrographis 10-20 part

Optimum weight proportioning of the present invention is:

10 parts of 20 parts of Radix Sophorae Flavescentiss of 15 parts of Radix Scutellariaes of 5 parts of Radixs Astragali of Radix Pseudostellariae

20 parts of 10 parts of Radix Bupleuri of 20 parts of Herba Hyperici Japonici of 20 parts of Radix Salviae Miltiorrhizaes of Rhizoma Polygoni Cuspidati

10 parts of 15 portions of Herba Solani Nigris of 5 parts of Herba Asteris Flaccidies of 20 parts of muskmelon pedicels of Herba Artemisiae Scopariae

5 parts of 15 parts of Nidus Vespaes of 10 portions of Herba Solani Lyratis of 20 parts of Folium Aloes of Rhizoma Picrorhizae

20 parts in 20 portions of Radix Glycyrrhizaes of 10 portions of Folium Isatidiss of 20 parts of Rhizoma Osmundae of Herba Scutellariae Barbatae

10 parts of Herba Andrographis

Above-mentioned each component is made medicine production method of the present invention is:

1, earlier with Radix Pseudostellariae, muskmelon pedicel, Nidus Vespae drying and crushing to 120 order fine powder;

2, getting the Radix Astragali, Radix Scutellariae, Radix Sophorae Flavescentis, Rhizoma Polygoni Cuspidati, Radix Salviae Miltiorrhizae, Herba Hyperici Japonici, Radix Bupleuri, Herba Artemisiae Scopariae, Herba Asteris Flaccidi, Herba Solani Nigri, Picrorhiza scrophulariiflora, Folium Aloe, Herba Solani Lyrati, Herba Scutellariae Barbatae, Rhizoma Osmundae, Folium Isatidis, Radix Glycyrrhizae, punching connects and is ground into 120 order fine powders after air-dry;

3, with above-mentioned whole powder components by after the described mixed, under 100 ℃, carried out the ripening sterilization treatment 10-30 minute, the powder medicine of the hepatitis B that both can obtain medical treatment.

The present invention shows that through clinical use result following advantage is arranged:

1, the present invention selects the heat-clearing and detoxifying herb of specially controlling hepatitis B virus for use, utilizes the comprehensive effect together of various Chinese medicines, suppresses to remove hepatitis B virus in the body, and effect is fairly obvious, and the every viral index of hepatitis B is all turned out cloudy.

2, medicine of the present invention is nontoxic to human body, taking convenience, and hepatitis B treating is fast, the cure rate height.

3, the present invention can replace other all kinds of Chinese medicine and western medicine of controlling hepatitis B, according to clinical observation statistical result be: 1350 people to 1350 routine patients, male 750 people wherein, age is in 10-40 year, women 600 people, age is in 15-40 year, take 1-3 course of treatment of this treating hepatitis B agent, one month is a course of treatment, hepatitis B surface antigen, e antigen, core antibody are all turned out cloudy after one of them course of treatment 950 people, hepatitis B surface antigen, e antigen, core antibody have 400 people that have that 1-2 item index turns out cloudy, and after three courses of treatment, 1350 human hepatitis B virus, three cloudy diseases are all turned out cloudy.Find out that from statistical result the negative conversion rate of taking this medicine hepatitis B virus three cloudy diseases is apparently higher than the Western medicine interferon, effect is also much better than other Chinese medicine treating the liver medicine.

Embodiment:

Take by weighing raw material by following proportioning:

The Radix Pseudostellariae 10 gram Radixs Astragali 30 gram Radix Scutellariaes 25 gram Radix Sophorae Flavescentiss 20 grams

Rhizoma Polygoni Cuspidati 25 gram Radix Salviae Miltiorrhizaes 25 gram Herba Hyperici Japonici 20 gram Radix Bupleuri 25 grams

Herba Artemisiae Scopariae 25 gram muskmelon pedicels 10 gram Herba Asteris Flaccidies 20 cron certain herbaceous plants with big flowers 20 grams

Rhizoma Picrorhizae 30 gram Folium Aloes 10 gram Herba Solani Lyratis 15 gram Nidus Vespaes 5 grams

Herba Scutellariae Barbatae 20 gram Rhizoma Osmundae 10 gram Folium Isatidiss 20 gram Radix Glycyrrhizaes 20 grams

Herba Andrographis 10 grams

Production method is as follows:

Earlier with Radix Pseudostellariae, muskmelon pedicel, Nidus Vespae drying and crushing to 120 order fine powder; Getting the Radix Astragali, Radix Scutellariae, Radix Sophorae Flavescentis, Rhizoma Polygoni Cuspidati, Radix Salviae Miltiorrhizae, Herba Hyperici Japonici, Radix Bupleuri, Herba Artemisiae Scopariae, Herba Asteris Flaccidi, Herba Solani Nigri, Picrorhiza scrophulariiflora, Folium Aloe, Herba Solani Lyrati, Herba Scutellariae Barbatae, Rhizoma Osmundae, Folium Isatidis, Radix Glycyrrhizae, punching connects and is ground into 120 order fine powders after air-dry; Above-mentioned whole powder components by after the described mixed, were carried out the ripening sterilization treatment 10-30 minute, the powder medicine of the hepatitis B that both can obtain medical treatment under 100 ℃.

Instructions of taking:

Each 15 grams are obeyed three every day, and ante cibum, boiled water was taken after mixing it with water, and one month is a course of treatment.

Claims (5)

1, a kind of Chinese medicine for the treatment of hepatitis B is characterized in that it is made by the following weight proportion raw material:

Radix Pseudostellariae 5-10 part Radix Astragali 20-30 part Radix Scutellariae 20-30 part

Radix Sophorae Flavescentis 10-20 part Rhizoma Polygoni Cuspidati 20-30 part Radix Salviae Miltiorrhizae 20-30 part

Herba Hyperici Japonici 10-20 part Radix Bupleuri 20-30 part Herba Artemisiae Scopariae 20-30 part

Muskmelon pedicel 5-10 part Herba Asteris Flaccidi 10-20 part Herba Solani Nigri 10-20 part

Rhizoma Picrorhizae 20-30 part Folium Aloe 10-20 part Herba Solani Lyrati 10-20 part

Nidus Vespae 5-10 part Herba Scutellariae Barbatae 20-30 part Rhizoma Osmundae 5-10 part

Folium Isatidis 20-30 part Radix Glycyrrhizae 10-30 part Herba Andrographis 10-20 part.

2, the Chinese medicine of treatment hepatitis B according to claim 1 is characterized in that the weight proportion of described each raw material is:

10 parts of 20 parts of Radix Sophorae Flavescentiss of 15 parts of Radix Scutellariaes of 5 parts of Radixs Astragali of Radix Pseudostellariae

20 parts of 10 parts of Radix Bupleuri of 20 parts of Herba Hyperici Japonici of 20 parts of Radix Salviae Miltiorrhizaes of Rhizoma Polygoni Cuspidati

10 parts of 15 portions of Herba Solani Nigris of 5 parts of Herba Asteris Flaccidies of 20 parts of muskmelon pedicels of Herba Artemisiae Scopariae

5 parts of 15 parts of Nidus Vespaes of 10 portions of Herba Solani Lyratis of 20 parts of Folium Aloes of Rhizoma Picrorhizae

20 parts in 20 portions of Radix Glycyrrhizaes of 10 portions of Folium Isatidiss of 20 parts of Rhizoma Osmundae of Herba Scutellariae Barbatae

10 parts of Herba Andrographis.

3, the Chinese medicine of treatment hepatitis B according to claim 1 and 2 is characterized in that said medicament is a said dosage form on any pharmaceutics.

4, the Chinese medicine of treatment hepatitis B according to claim 3 is characterized in that said medicament is powder or piece agent.

5, the medicine of treatment hepatitis B according to claim 1 and 2 is characterized in that:

Earlier with Radix Pseudostellariae, muskmelon pedicel, Nidus Vespae drying and crushing to 120 order fine powder; Getting the Radix Astragali, Radix Scutellariae, Radix Sophorae Flavescentis, Rhizoma Polygoni Cuspidati, Radix Salviae Miltiorrhizae, Herba Hyperici Japonici, Radix Bupleuri, Herba Artemisiae Scopariae, Herba Asteris Flaccidi, Herba Solani Nigri, Picrorhiza scrophulariiflora, Folium Aloe, Herba Solani Lyrati, Herba Scutellariae Barbatae, Rhizoma Osmundae, Folium Isatidis, Radix Glycyrrhizae, punching connects and is ground into 120 order fine powders after air-dry; Above-mentioned whole powder components by after the described mixed, were carried out the ripening sterilization treatment 10-30 minute, the powder medicine of the hepatitis B that both can obtain medical treatment under 100 ℃.