CN1260834A - 抗微生物肽 - Google Patents

抗微生物肽 Download PDF

Info

Publication number
CN1260834A
CN1260834A CN98806203A CN98806203A CN1260834A CN 1260834 A CN1260834 A CN 1260834A CN 98806203 A CN98806203 A CN 98806203A CN 98806203 A CN98806203 A CN 98806203A CN 1260834 A CN1260834 A CN 1260834A
Authority
CN
China
Prior art keywords
sequence
seq
polypeptide
amino acids
antimicrobial
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN98806203A
Other languages
English (en)
Chinese (zh)
Inventor
H·S·欧尔森
S·M·鲁本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of CN1260834A publication Critical patent/CN1260834A/zh
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN98806203A 1997-05-14 1998-05-14 抗微生物肽 Pending CN1260834A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4641597P 1997-05-14 1997-05-14
US60/046,415 1997-05-14

Publications (1)

Publication Number Publication Date
CN1260834A true CN1260834A (zh) 2000-07-19

Family

ID=21943326

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98806203A Pending CN1260834A (zh) 1997-05-14 1998-05-14 抗微生物肽

Country Status (8)

Country Link
US (3) US6143498A (https=)
EP (1) EP0980431A1 (https=)
JP (1) JP2001527412A (https=)
KR (1) KR20010012554A (https=)
CN (1) CN1260834A (https=)
AU (1) AU737710B2 (https=)
CA (1) CA2290781A1 (https=)
WO (1) WO1998051794A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107064507A (zh) * 2009-04-03 2017-08-18 生物梅里埃公司 用于结肠直肠癌体外诊断的防卫素原‑a6测定方法
US10087227B2 (en) 2013-03-15 2018-10-02 Genentech, Inc. Nucleic acids encoding IL-22 Fc fusion proteins
CN116496916A (zh) * 2022-12-27 2023-07-28 安徽斯拜科生物科技有限公司 一种高产hbd-2的毕赤酵母工程菌株及其制备方法和应用

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6984622B2 (en) * 1998-03-25 2006-01-10 The Regents Of The University Of California Use of lipopolysaccharides to manage corneal infections and wounds
WO2001023002A1 (en) * 1999-09-30 2001-04-05 National Jewish Medical And Research Center Method for inhibition of pathogenic microorganisms
ATE319740T1 (de) * 2000-06-08 2006-03-15 Ipf Pharmaceuticals Gmbh Verfahren zur gewinnung und anwendung von antibiotisch wirksamen peptiden zur behandlung von infektionskrankheiten
US6846804B2 (en) * 2000-06-29 2005-01-25 University Of Maryland, College Park Office Of Technology Commercialization Construction of a structural variant of sublancin to facilitate its isolation and use in bioremediation of environmental contamination by gram-positive spore formers such as bacillus anthrasis
DE10129983A1 (de) * 2001-06-13 2003-01-30 Univ Eberhard Karls Antimikrobiell wirkendes Peptid
US8329865B2 (en) * 2001-06-13 2012-12-11 Eberhard-Karls-Univresitaet Tuebingen Universitaetsklinikum Antimicrobially active peptides
US7507787B2 (en) * 2001-12-03 2009-03-24 The University Of British Columbia Effectors of innate immunity
AU2003215257A1 (en) * 2002-02-19 2003-09-09 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Modified defensins and their use
DE60335101D1 (de) 2002-04-25 2011-01-05 Toagosei Co Ltd Antimikrobielles polypeptid und nutzung davon
US7033769B2 (en) * 2002-05-23 2006-04-25 The United States Of America As Represented By The Secretary Of The Army Method for discovering one or more peptides adapted for specific binding to a microorganism of interest
JP4524671B2 (ja) 2003-10-29 2010-08-18 東亞合成株式会社 抗菌ペプチド及びその利用
JP4507080B2 (ja) 2004-07-30 2010-07-21 東亞合成株式会社 抗菌ペプチド及びその利用
JP4730584B2 (ja) 2004-12-06 2011-07-20 東亞合成株式会社 抗菌ペプチド及びその利用
US7485619B2 (en) * 2005-01-31 2009-02-03 Yeon Sook KIM Antimicrobial agent
WO2006088010A1 (ja) 2005-02-15 2006-08-24 Toagosei Co., Ltd. 抗菌ペプチド及びその利用
US20070231833A1 (en) * 2005-05-23 2007-10-04 Arcidiacono Steven M Labeled antimicrobial peptides and method of using the same to detect microorganisms of interest
JP2009535027A (ja) * 2006-04-27 2009-10-01 シンガポール ヘルス サービシーズ ピーティーイー リミテッド 抗菌ペプチド
US20100150985A1 (en) * 2008-04-24 2010-06-17 George Just Dental Implant, Endodontic Instrument, and Dental Filling Material Coated with a Peptide-Based Antimicrobial and Methods of Using and Making the Same
WO2011137368A2 (en) 2010-04-30 2011-11-03 Life Technologies Corporation Systems and methods for analyzing nucleic acid sequences
US9268903B2 (en) 2010-07-06 2016-02-23 Life Technologies Corporation Systems and methods for sequence data alignment quality assessment
KR101303299B1 (ko) * 2010-10-08 2013-09-03 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 항균 펩타이드의 피부 세포 재생 촉진제로서의 신규한 용도
CN103533947A (zh) 2010-12-28 2014-01-22 卡梅迪斯有限公司 用于治疗和预防感染的植物提取物
US10967031B2 (en) 2010-12-28 2021-04-06 Kamedis Ltd. Synergistic herbal compositions with prebiotic properties for treatment of skin infections, allergies and inflammation
US11612225B2 (en) * 2018-05-03 2023-03-28 Nicholas Schwartz Securing beach net
CN115428088A (zh) 2020-02-13 2022-12-02 10X基因组学有限公司 用于基因表达和dna染色质可及性的联合交互式可视化的系统和方法
EP4121087A4 (en) 2020-03-18 2024-04-03 The University of Hong Kong ANTI-VIRAL PEPTIDE COMPOSITIONS AND METHODS OF USE
EP4457237A4 (en) * 2021-12-27 2025-11-12 Versitech Ltd ANTIVIRAL PEPTIDES AND THEIR METHODS OF USE

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5432270A (en) * 1990-10-25 1995-07-11 Zasloff; Michael A. DNA encoding tracheal antimicrobial peptides
AU670108B2 (en) * 1992-09-11 1996-07-04 Becton Dickinson & Company Improved antibodies to plasmodium falciparum
US5470955A (en) * 1993-02-02 1995-11-28 Dartmouth College Antibodies which specifically bind mcl-1 polypeptide
DE4427531A1 (de) * 1994-08-04 1996-02-08 Forssmann Wolf Georg Humanes zirkulierendes beta-Defensin hBD-1
WO1997022624A2 (de) * 1995-12-16 1997-06-26 Beiersdorf Ag Gegen bakterien, mycota und viren wirksame vertebratenproteine und dessen kosmetische zubereitungen
DE19629119A1 (de) * 1995-12-16 1997-06-19 Beiersdorf Ag Gegen Bakterien, Mycota und Viren wirksame kosmetische Zubereitungen enthaltend Vertebratenproteine

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107064507A (zh) * 2009-04-03 2017-08-18 生物梅里埃公司 用于结肠直肠癌体外诊断的防卫素原‑a6测定方法
CN107064507B (zh) * 2009-04-03 2021-02-05 生物梅里埃公司 用于结肠直肠癌体外诊断的防卫素原-a6测定方法
US10087227B2 (en) 2013-03-15 2018-10-02 Genentech, Inc. Nucleic acids encoding IL-22 Fc fusion proteins
US10160793B2 (en) 2013-03-15 2018-12-25 Genentech, Inc. Methods of treating inflammatory bowel disease using IL-22 Fc fusion proteins
US10544198B2 (en) 2013-03-15 2020-01-28 Genentech, Inc. Methods of accelerating or improving wound healing using IL-22 FC fusion proteins
US10584155B2 (en) 2013-03-15 2020-03-10 Genentech, Inc. Pharmaceutical compositions of IL-22 Fc fusion proteins
US11130791B2 (en) 2013-03-15 2021-09-28 Genentech, Inc. Methods for treating metabolic syndrome using IL-22 Fc fusion proteins
US11136365B2 (en) 2013-03-15 2021-10-05 Genentech, Inc. Methods for preventing or treating cardiovascular conditions using il-22 fc fusion proteins
US11155591B2 (en) 2013-03-15 2021-10-26 Genentech, Inc. Methods of treating acute pancreatitis using IL-22 fc fusion proteins
US11332507B2 (en) 2013-03-15 2022-05-17 Genentech, Inc. IL-22 Fc fusion proteins
CN116496916A (zh) * 2022-12-27 2023-07-28 安徽斯拜科生物科技有限公司 一种高产hbd-2的毕赤酵母工程菌株及其制备方法和应用

Also Published As

Publication number Publication date
US6420116B1 (en) 2002-07-16
CA2290781A1 (en) 1998-11-19
JP2001527412A (ja) 2001-12-25
US20050004355A1 (en) 2005-01-06
AU7385898A (en) 1998-12-08
US6143498A (en) 2000-11-07
EP0980431A1 (en) 2000-02-23
AU737710B2 (en) 2001-08-30
KR20010012554A (ko) 2001-02-15
US7223840B2 (en) 2007-05-29
WO1998051794A1 (en) 1998-11-19

Similar Documents

Publication Publication Date Title
CN1260834A (zh) 抗微生物肽
US6479254B2 (en) Apoptosis inducing molecule II
CN1107072C (zh) 编程性细胞死亡诱导分子ⅱ
CN1299407A (zh) 血管内皮生长因子2
US6419917B1 (en) Human chemotactic protein
CA2268022A1 (en) Galectin 8, 9, 10 and 10sv
WO1998033915A1 (en) Breast cancer specific gene 1
CN1295579A (zh) 角质细胞生长因子2的治疗应用
US20030166898A1 (en) Myelin oligodendrocyte glycoprotein-like protein (MOGp)
WO1998033912A9 (en) MYELIN OLIGODENDROCYTE GLYCOPROTEIN-LIKE PROTEIN (MOGp) AND METHODS OF USE
US6495520B2 (en) Apoptosis Inducing Molecule II and methods of use
WO1998053069A2 (en) Gdnf receptors
WO1998044112A9 (en) Human muscle derived growth factor - cardiac and pancreatic protein (capp) and gene
US20020110867A1 (en) Cardiac and pancreatic protein and gene
CA2335655A1 (en) Keratinocyte derived interferon
NZ513514A (en) Antimicrobial peptide
WO1998044111A1 (en) Thymus receptor tyrosine kinase (trtk) and methods of use
NZ500864A (en) Isolated nucleic acid molecules encoding human defensin peptide
MXPA99010235A (en) Antimicrobial peptide
AU5988801A (en) Antimicrobial peptide
AU734384B2 (en) Apoptosis inducing molecule II
AU771013B2 (en) Apoptosis inducing molecule II
CN1703422A (zh) Meth1和meth2多核苷酸及多肽
US20050003437A1 (en) Human oncogene induced secreted protein I
AU2004202460A1 (en) Apoptosis Inducing Molecule II

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication