CN1244328C - 治疗或预防由nos功能减退诱发的疾病的药物 - Google Patents
治疗或预防由nos功能减退诱发的疾病的药物 Download PDFInfo
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- CN1244328C CN1244328C CN 97191338 CN97191338A CN1244328C CN 1244328 C CN1244328 C CN 1244328C CN 97191338 CN97191338 CN 97191338 CN 97191338 A CN97191338 A CN 97191338A CN 1244328 C CN1244328 C CN 1244328C
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- nos
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Abstract
Description
开始时 | 2周 | 4周 | 5周 | |
对照组DOCA组DOCA+BH4组 | 101.38(±7.12)107.03(±2.04)105.72(±5.63) | 102.85(±11.07)137.53(±4.63)120.54(±6.57) | 91.77(±7.88)153.53(±7.71)111.91(±7.52) | 111.70(±10.10)150.68(±3.35)107.78(±7.93) |
开始时 | 2周 | 4周 | 5周 | |
对照组DOCA组DOCA+BH4组 | 2.91±0.093.11±1.092.22±0.70 | 1.51±0.790.34±0.342.00±0.55 | 4.54±0.32测定灵敏度以下5.95±1.90 |
开始时 | 2周 | 4周 | 5周 | |
对照组DOCA组DOCA+BH4组 | 26.76±3.0123.77±0.7721.87±0.60 | 21.71±0.6119.49±2.5235.58±3.74 | 27.79±2.0315.93±3.4652.60±13.13 | 34.96±0.9619.25±1.9634.26±4.08 |
开始时 | 2周 | 4周 | 5周 | |
对照组DOCA组DOCA+BH4组 | 390.67±18.49376.00±3.69383.40±10.83 | 433.33±21.49399.67±19.44386.40±12.84 | 456.00±21.63430.33±20.08431.20±13.31 | 458.00±20.43435.67±23.34446.80±15.81 |
开始时 | 2周 | 3周 | 4周 | 5周 | 6周 | |
对照组DOCA组DOCA+BH4组 | 129.44(±2.20)132.00(±5.18)130.22(±3.75) | 119.44(±2.97)132.88(±3.88)133.60(±2.05) | 143.83(±0.62)162.28(±1.87)143.63(±0.85) | 151.20(±0.90)169.83(±2.57)150.90(±0.94) | 158.01(±1.63)182.98(±2.04)159.30(±2.84) | 161.91(±4.20)178.10(±9.85)162.95(±1.52) |
开始时 | 4周 | 6周 | |
对照组DOCA组DOCA+BH4组 | 22.29±1.5317.87±1.6524.26±1.58 | 25.13±1.233.18±2.1445.21±10.31 | 43.07±7.2416.33±5.7771.78±32.08 |
坏死性肾小球炎 | 坏死性血管炎 | |
对照组DOCA组DOCA+BH4组 | 0.06±0.0610.78±0.772.47±1.07 | 0.00±0.009.03±1.653.34±0.94 |
Claims (7)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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JP23110396 | 1996-08-30 | ||
JP231103/96 | 1996-08-30 | ||
JP92213/97 | 1997-04-10 |
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Publication Number | Publication Date |
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CN1204963A CN1204963A (zh) | 1999-01-13 |
CN1244328C true CN1244328C (zh) | 2006-03-08 |
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CN 97191338 Expired - Lifetime CN1244328C (zh) | 1996-08-30 | 1997-08-29 | 治疗或预防由nos功能减退诱发的疾病的药物 |
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JP4836388B2 (ja) * | 2002-03-22 | 2011-12-14 | 第一三共株式会社 | eNOS発現に起因する疾患の予防または治療薬 |
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