CN1243717A - Medicine for curing common cold and cough and its preparing process - Google Patents
Medicine for curing common cold and cough and its preparing process Download PDFInfo
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- CN1243717A CN1243717A CN 98103456 CN98103456A CN1243717A CN 1243717 A CN1243717 A CN 1243717A CN 98103456 CN98103456 CN 98103456 CN 98103456 A CN98103456 A CN 98103456A CN 1243717 A CN1243717 A CN 1243717A
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Abstract
A medicine for treating common cold and cough is prepared from 22 Chinese-medicinal materials including ephedra, mint, almond, schizonepeta, American ginseng, etc. through proportioning, dedocting, extraction, filter, concentrating and making instant powder, or oral liquid, or tablet, or capsule. Its advantage is high curative effect.
Description
The present invention relates to pharmaceutical composition for the treatment of cold cough and preparation method thereof, refer to the vegetable Chinese herbal medicine to be medicine of the treatment cold cough made of raw material and preparation method thereof especially.
The evil poison of diseases caused by exogenous pathogenic factor pathogenic wind-warm is a kind of common frdquently encountered disease of harm humans, often many more refractory diseases are gone into by diseases caused by exogenous pathogenic factor, cause by flu as the viral encephalitis due to the influenza, viral myocarditis, viral upper respiratory tract infection etc., its characteristics of incidence is: morbidity early, the most common, easily form fashion trend, consequence is serious.
The Chinese medicine and western medicine of more existing treatment anemopyretic cold exists such-and-such deficiency, and effect is unsatisfactory.Most of Western medicine is mitigation symptoms temporarily, and a Zhi Qibiao is Zhi Qiben not, and only effective to some symptom in the disease, and the easily recurrence of treatment back all can not be played basic therapeutical effect to most of patient; And treat the Chinese patent medicine of this type of disease, exist take effect slow, side effect is big and take shortcoming such as inconvenience.
The object of the present invention is to provide a kind of pure treatment by Chinese herbs agent, the various heat symptom-complexs that can prevent and treat due to the evil poison of diseases caused by exogenous pathogenic factor pathogenic wind-warm are suffered from.Instant effect, toxic and side effects is little.
Another object of the present invention provides a kind of preparation method of evil therapeutic agent of the pathogenic wind-warm of catching a cold, and can be made into electuary, oral liquid, tablet or capsule.Good effect, taking convenience.
Technical scheme of the present invention is based on motherland's medical science to pathogenic wind-warm diseases caused by exogenous pathogenic factor and merging pathogenetic understanding of symptom and Therapeutic Principle, achieve with reference to modern pharmacological research, from motherland's medical treasure-house, the natural plants that filters out relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, heat-clearing and toxic substances removing, invigorating the spleen and replenishing QI, helps diabetes involving middle-JIAO to eat is according to the theory of Chinese medical science prescription.Loose lung qi, reinforcing body resistance, Gu of this prescription relieving the exterior syndrome with drugs of pungent in flavor and cool in nature, relieving cough and resolving phlegm, a surname protects gastric qi, and it is normal that lung qi a surname is sent out, the heresy Zhengan County that dispels.
The present invention treats the medicine of cold cough and makes (consumption is weight portion) by following ingredients: Chinese ephedra 6-12 peppermint 6-12 almond 10-20 schizonepeta 10-20 Radix Astragali 20-50 tendril-leaved fritillary bulb 6-20 ginger 5-12 capsule of weeping forsythia 10-50 mulberry leaf 10-50 chrysanthemum 10-50 honeysuckle 10-100 leaf of bamboo 10-100 Fermented Soybean 10-50 great burdock achene 10-20 balloonflower root 10-15 dried orange peel 10-20 tuber of pinellia 6-12 Radix Glycyrrhizae 5-12
The medicine that the present invention treats cold cough can also add following raw material (consumption is a weight portion): Radix Panacis Quinquefolii 10-15 Fructus Crataegi 10-100 Massa Medicata Fermentata 10-50 Fructus Hordei Germinatus 10-50
The best proportioning that the present invention treats the medicine of cold cough is (consumption is a weight portion): Herba Ephedrae 6 Herba Menthaes 6 Semen Armeniacae Amarums 10 Herba Schizonepetae 10 Radixs Astragali 20 Bulbus Fritillariae Cirrhosae 6 Rhizoma Zingiberis Recenss 5 Fructus Forsythiaes 10 Folium Mori 10 Flos Chrysanthemis 10 Flos Loniceraes 10 Folium Bambusaes 10 Semen Sojae Preparatums 10 Fructus Arctiis 10 Radix Platycodoniss 10 Pericarpium Citri Reticulataes 10 Rhizoma Pinelliaes 6 Radix Glycyrrhizaes 5
The present invention treats in the best proportioning of medicine of cold cough can also add following raw material (consumption is a weight portion): Radix Panacis Quinquefolii 10 Fructus Crataegis 10 Massa Medicata Fermentata 10 Fructus Hordei Germinatus 10
Wherein the medicine of relieving the exterior syndrome with drugs of pungent in flavor and cool in nature can be dispersed the wind heat pathogenic factor in the exterior, dispel pathogenic wind-warm virus, basic some cardinal symptoms that solve, as: fever and headache, aversion to heat spontaneous perspiration etc., thereby make the heresy Zhengan County that dispels, for diseases caused by exogenous pathogenic factor pathogenic warmth and body void person the present invention a small amount of Radix Panacis Quinquefolii energy strengthening vital QI to eliminate pathogenic factors can be arranged, can play the effect of prevent disease opposing exopathogen again, wherein the evil malicious the infected of pathogenic wind-warm is many mostly, intrinsic heat in the body, so inducing sweat is the agent that adds poison outside the heat clearing away under the prerequisite of leading, it brings out the best in each other expelling pathogen from the exterior and clearing up internal heat, the evil poison of diseases caused by exogenous pathogenic factor pathogenic wind-warm, pathogenic heat makes the space between skin and muscles obturation, accumulate in the interior-heat make in gas do not declare, and the expectorant stasis of blood that arrives is in the lining, so add Bulbus Fritillariae Cirrhosae, the genus clearing away lung-heat of the Radix Astragali must be slided then, and pathogenic factor in the exterior should loose.For the digestive function that is suitable for children's and help taking this medicine, play a role better and play the purpose of school flavor simultaneously, can increase Fructus Crataegi, Massa Medicata Fermentata, Fructus Hordei Germinatus.
Above-mentioned each component is made the preparation method that the present invention treats the medicine of cold cough is:
1, takes by weighing each component (weight portion) by following prescription: Herba Ephedrae 6 Herba Menthaes 6 Semen Armeniacae Amarums 10 Herba Schizonepetae 10 Radixs Astragali 20 Bulbus Fritillariae Cirrhosae 6 Rhizoma Zingiberis Recenss 5 Fructus Forsythiaes 10 Folium Mori 10 Flos Chrysanthemis 10 Flos Loniceraes 10 Folium Bambusaes 10 Semen Sojae Preparatums 10 Fructus Arctiis 10 Radix Platycodoniss 10 Pericarpium Citri Reticulataes 10 Rhizoma Pinelliaes 6 Radix Glycyrrhizaes 5 Radix Panacis Quinquefoliis 10 Fructus Crataegis 10 Massa Medicata Fermentata 10 Fructus Hordei Germinatus 10
2, above medicine is collected volatile oil (Aromatic water) back dried up liquid of branch and medicinal residues in the ratio that 100 gram crude drugs extract 20 milliliters of volatile oil with the way of distillation;
3, medicinal residues decoct with water twice again;
4, merge above-mentioned three decocting liquids, be concentrated into the thick paste shape after dried;
5, with after the above-mentioned oven dry thing pulverizing, add dextrin and sugar, its weight ratio is 1 part of medicine: 3 parts of dextrin: granulate behind 1 part of sugared mix homogeneously;
6, packing behind the adding volatile oil mixing.
This medicine can be made into multiple dosage form, as electuary, oral liquid, capsule, tablet etc.
Advantage of the present invention is good effect, instant effect, has multiple dosage form selective, taking convenience.
For showing that the present invention is to the therapeutic effect of medicine to cold cough, the present invention is through the clinical observation of 100 routine systems, cough after selecting to catch a cold from clinic case or other are as measles, pneumonia, influenza, chickenpox, parotitis, acute laryngitis, aphonia, but common symptoms has symptoms such as heating, headache, nasal obstruction, xerostomia pharyngalgia.Wherein course of disease 1-5 days, 43 examples; 5-10 days, 34 examples; Person's 23 examples more than 10 days.
Instructions of taking: each 20 milliliters of oral liquids or 3-7 sheet medicine or 3-7 capsules or electuary 30 grams, every day 3-4 time.In addition also to age groups, 10-20 year wherein, 18 examples; 20-30 year, 23 examples: 30-40 year, 43 examples; In 40-50 year, the patient of 16 examples has carried out the clinical observation test, and method is the same.
The statistical result total effective rate is 99%.
Embodiment
Take by weighing raw material (consumption is a weight portion) by following proportioning, every part is 1 gram.Herba Ephedrae 6 Herba Menthaes 6 Semen Armeniacae Amarums 10 Herba Schizonepetae 10 Radix Panacis Quinquefoliis 10 Radixs Astragali 20 Fructus Crataegis 10 Massa Medicata Fermentata 10 Fructus Hordei Germinatus 10 Bulbus Fritillariae Cirrhosae 6 Rhizoma Zingiberis Recenss 5 Fructus Forsythiaes 10 Folium Mori 10 Flos Chrysanthemis 10 Flos Loniceraes 10 Folium Bambusaes 10 Semen Sojae Preparatums 10 Fructus Arctiis 10 Radix Platycodoniss 10 Pericarpium Citri Reticulataes 10 Rhizoma Pinelliaes 6 Radix Glycyrrhizaes 5
Embodiment 1: electuary adds 8 times of water gagings immersions with above-mentioned medical material and decocted 2 hours after 1 hour, collects volatile oil (Aromatic water) back dried up liquid of branch and medicinal residues in the ratios of 20 milliliters of volatile oil of 100 gram crude drugs extractions with the way of distillation simultaneously; Second fries in shallow oil and the 3rd fries in shallow oil the decocting that all adds 5 times of amounts and boiled 1 hour; Merge above-mentioned three decocting liquids, adopt membrane evaporator to be concentrated into thick paste shape (paste-forming rate is 12%) after vacuum drying treatment; Be 1 part of medicine by weight after the pulverizing: 3 parts of dextrin: the ratio of 1 portion of sugar adds dextrin and sugar, and (12 mesh sieve) back of granulating is with 10 mesh sieve granulate, add volatile oil mix thoroughly after packing immediately, every bag 9 restrains.
Embodiment 2: oral liquid is collected volatile oil (Aromatic water) with above medical material in the ratio that 100 gram crude drugs extract 20 milliliters of volatile oil; After separating medicinal residues and water liquid medicinal residues are decocted with water twice again, merge three times decocting liquid, the ratio that adopts membrane evaporator to be concentrated into medicinal liquid and crude drug in whole is 1 milliliter: behind 1 gram, precipitate concentrated solution with gelatin, placed 24 hours, filter; The filtrate reconcentration to the ratio of crude drug in whole be 1 milliliter: add 95% ethanol behind 3 grams and make and contain the alcohol amount and reach 65% back and place and carried out precipitate with ethanol in 48 hours, filter and also reclaim ethanol; Adding distilled water to the ratio of medicine liquid volume and crude drug in whole is 1 milliliter in medicinal liquid: behind 1 gram, add above-mentioned volatile oil and an amount of antiseptic nipalgin and become 20 milliliters/with fill behind the flavoring agent protein sugar mixing, sterilization.
Embodiment 3: tablet is collected volatile oil (Aromatic water) back branch dried up liquid and medicinal residues in the ratio that 100 gram crude drugs extract 20 milliliters of volatile oil with the way of distillation with above-mentioned medical material; Second fries in shallow oil and the 3rd fries in shallow oil the decocting that all adds 5 times of amounts and boiled 1 hour; Merge above-mentioned three decocting liquids, adopt membrane evaporator to be concentrated into thick paste shape (paste-forming rate is 14%) after vacuum drying treatment; Be 1 part of medicine by weight after the pulverizing: 3 parts of dextrin: the ratio of 1 portion of sugar adds dextrin and sugar, and (12 mesh sieve) back of granulating is with 10 mesh sieve granulate, add volatile oil mix thoroughly after tabletting immediately, every 0.3 restrains.
Embodiment 4: capsule is collected volatile oil (Aromatic water) back branch dried up liquid and medicinal residues in the ratio that 100 gram crude drugs extract 20 milliliters of volatile oil with the way of distillation with above-mentioned medical material; Second fries in shallow oil and the 3rd fries in shallow oil the decocting that all adds 5 times of amounts and boiled 1 hour; Merge above-mentioned three decocting liquids, adopt membrane evaporator to be concentrated into thick paste shape (paste-forming rate is 14%) after vacuum drying treatment; Be 1 part of medicine by weight after the pulverizing: 3 parts of dextrin: the ratio of 1 portion of sugar adds dextrin and sugar, and (12 mesh sieve) back of granulating is with 10 mesh sieve granulate, and encapsulated immediately after adding volatile oil is mixed thoroughly, every explosive payload is 0.3 gram.Every day 3-4 time, each 3-10 grain, children's is cut down according to the circumstance.
Model case:
Case 1: Kong Qiuping, the woman, 46 years old is the cadre of the Henan Province tax bureau, be that diagnostic result move in certain provincial hospital with fever of unknown and tonsillitis in March, 98, be in hospital 20 days, and used antibiotic therapy every day, comprising medicines such as cefalexin capsules, first ensiform needle No. five, No. six, its burning is not moved back, automatically require to leave hospital the back during to my outpatient service, patient's disease is seen fever and cough, is told yellow sputum, headache, general pain, weak, 38 ℃ of body temperature.Move back through the 1st day heat of clothes medicine of the present invention, only coughed recovery from illness after 3 days on the 2nd day.
Case 2: 35 years old river man of its woods of Zhao man economizes through property firm of association, and it is undesirable to suffer from 1 year clothes of cough Chinese and western drugs effect in 1996, takes this Chinese medicine and heals after the people makes referrals to my clinic.Afterwards, it is also fine that the son of Mr.'s Zhao Qilin friend Zhao and army trouble cough is taken this medication effect equally.December in 1997 Mr. Zhao Qilin on the 22nd is because of headache due to common cold heating, pharyngalgia, takes this medicine and heals.
Case 3: golden red profit woman 29 years old, Chinese medicine and western medicine because of generating heat, have a headache, coughing ten days, is obeyed by Henan Province Construction Bank, and unsatisfactory curative effect is taken the recovery from illness in 2 days of this Chinese medicine subsequently.
Claims (14)
1, a kind of medicine for the treatment of cold cough is characterized in that it is the medicament of being made by following raw material (weight portion): Herba Ephedrae 6-12 Herba Menthae 6-12 Semen Armeniacae Amarum 10-20 Herba Schizonepetae 10-20 Radix Astragali 20-50 Bulbus Fritillariae Cirrhosae 6-20 Rhizoma Zingiberis Recens 5-12 Fructus Forsythiae 10-50 Folium Mori 10-50 Flos Chrysanthemi 10-50 Flos Lonicerae 10-100 Folium Bambusae 10-100 Semen Sojae Preparatum 10-50 Fructus Arctii 10-20 Radix Platycodonis 10-15 Pericarpium Citri Reticulatae 10-20 Rhizoma Pinelliae 6-12 Radix Glycyrrhizae 5-12
2, the medicine of treatment cold cough according to claim 1, wherein the composition of each raw material is (weight portion): Herba Ephedrae 6 Herba Menthaes 6 Semen Armeniacae Amarums 10 Herba Schizonepetae 10 Radixs Astragali 20 Bulbus Fritillariae Cirrhosae 6 Rhizoma Zingiberis Recenss 5 Fructus Forsythiaes 10 Folium Mori 10 Flos Chrysanthemis 10 Flos Loniceraes 10 Folium Bambusaes 10 Semen Sojae Preparatums 10 Fructus Arctiis 10 Radix Platycodoniss 10 Pericarpium Citri Reticulataes 10 Rhizoma Pinelliaes 6 Radix Glycyrrhizaes 5
3,, it is characterized in that also containing in its prescription following raw material (weight portion) according to the medicine of claim 1 or described treatment cold cough:
Radix Panacis Quinquefolii 10-15 Fructus Crataegi 10-100 Massa Medicata Fermentata 10-50 Fructus Hordei Germinatus 10-50
4,, it is characterized in that containing in the prescription following raw material (weight portion) according to the medicine of the said treatment cold cough of claim 2:
Radix Panacis Quinquefolii 10 Fructus Crataegis 10 Massa Medicata Fermentata 10 Fructus Hordei Germinatus 10
5,, it is characterized in that said medicament is a said dosage form on any pharmaceutics according to the medicine of claim 1,2,3 or 4 described treatment cold coughs.
6, the medicine of treatment cold cough according to claim 5 is characterized in that said medicament is electuary, oral liquid, tablet or capsule.
7, the preparation method of the medicine of the described treatment cold cough of claim 6, it is characterized in that above medicine is collected volatile oil (Aromatic water) in the ratio that 100 gram crude drugs extract 20 milliliters of volatile oil, after separating medicinal residues and water liquid medicinal residues are decocted with water twice again, merge three times decocting liquid, be concentrated into the thick paste shape and after the final vacuum dried, pulverize; Be 1 part of medicine more by weight: 3 parts of dextrin: the ratio of 1 portion of sugar adds dextrin and sugar, packing immediately behind the back adding volatile oil mixing of granulating.
8, the preparation method of the medicine of treatment cold cough according to claim 6 is characterized in that above medicine is collected volatile oil (Aromatic water) in the ratio that 100 gram crude drugs extract 20 milliliters of volatile oil; After separating medicinal residues and water liquid medicinal residues are decocted with water twice again, merge three times decocting liquid, the ratio that is concentrated into medicinal liquid and crude drug in whole is 1 milliliter: behind 1 gram, precipitate concentrated solution with gelatin, place, filter; The filtrate reconcentration to the ratio of crude drug in whole be 1 milliliter: add 95% ethanol behind 3 grams and make to contain and carry out precipitate with ethanol after the alcohol amount reaches 65%, filter and also reclaim ethanol; Adding distilled water to the ratio of medicine liquid volume and crude drug in whole weight in medicinal liquid is 1 milliliter: behind 1 gram, bottle after adding above-mentioned volatile oil and an amount of antiseptic and flavoring agent mixing, sterilize.
9, the preparation method of the medicine of treatment cold cough according to claim 6, it is characterized in that above medicine is collected volatile oil (Aromatic water) in the ratio that 100 gram crude drugs extract 20 milliliters of volatile oil, after separating medicinal residues and water liquid medicinal residues are decocted with water twice again, merge three times decocting liquid, be concentrated into the thick paste shape after pulverize after the vacuum drying treatment; Be 1 part of medicine more by weight: 3 parts of dextrin: the ratio of 1 portion of sugar adds dextrin and sugar, and the back of granulating adds behind the volatile oil mixing tabletting immediately.
10, the preparation method of the medicine of treatment cold cough according to claim 9 is characterized in that each tablet weighs 0.5 gram.
11, the preparation method of the medicine of treatment cold cough according to claim 6, it is characterized in that above medicine is collected volatile oil (Aromatic water) in the ratio that 100 gram crude drugs extract 20 milliliters of volatile oil, after separating medicinal residues and water liquid medicinal residues are decocted with water twice again, merge three times decocting liquid, be concentrated into the thick paste shape after after pulverizing after the vacuum drying treatment, be 1 part of medicine more by weight: 3 parts of dextrin: the ratio of 1 portion of sugar adds dextrin and sugar, direct encapsulated getting final product behind the back adding volatile oil mixing of granulating.
12, the preparation method of the medicine of treatment cold cough according to claim 11 is characterized in that each capsule 0.5 gram.
13, according to the preparation method of the medicine of claim 7,9 or 11 described treatment cold coughs, it is characterized in that the receipts cream rate of said thick paste is 10-15%.
14,, it is characterized in that said method for concentration concentrates for adopting membrane evaporator or vapor interlayer pot according to the preparation method of the medicine of claim 7,9 or 11 described treatment cold coughs.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98103456A CN1094055C (en) | 1998-07-30 | 1998-07-30 | Medicine for curing common cold and cough and its preparing process |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98103456A CN1094055C (en) | 1998-07-30 | 1998-07-30 | Medicine for curing common cold and cough and its preparing process |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1243717A true CN1243717A (en) | 2000-02-09 |
| CN1094055C CN1094055C (en) | 2002-11-13 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98103456A Expired - Fee Related CN1094055C (en) | 1998-07-30 | 1998-07-30 | Medicine for curing common cold and cough and its preparing process |
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| CN (1) | CN1094055C (en) |
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| WO2003045408A1 (en) * | 2001-11-29 | 2003-06-05 | Jiangsu Kanion Pharmaceutical Co., Ltd | An influenza treating pharmaceutical composition of traditional chinese medicine and method for preparation thereof |
| CN1305521C (en) * | 2005-10-26 | 2007-03-21 | 牟培新 | Cold treating medicine |
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| US7348033B1 (en) * | 2006-07-10 | 2008-03-25 | Horace Mitchell | Cold-remedy food supplement for simultaneously lowering blood pressure and sustaining blood sugar |
| CN100376272C (en) * | 2005-12-29 | 2008-03-26 | 颜怀伟 | Medicine and food dual purpose Chinese medicinal product for preventing and treating wind damp common cold and its manufacturing method |
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| CN1305521C (en) * | 2005-10-26 | 2007-03-21 | 牟培新 | Cold treating medicine |
| CN100376272C (en) * | 2005-12-29 | 2008-03-26 | 颜怀伟 | Medicine and food dual purpose Chinese medicinal product for preventing and treating wind damp common cold and its manufacturing method |
| US7348033B1 (en) * | 2006-07-10 | 2008-03-25 | Horace Mitchell | Cold-remedy food supplement for simultaneously lowering blood pressure and sustaining blood sugar |
| CN101366510B (en) * | 2008-09-03 | 2012-04-25 | 李富祥 | Infusion beverage for preventing common cold |
| CN102283890A (en) * | 2010-06-21 | 2011-12-21 | 许思东 | Externally applied drug acting on foreneck cavity Tiantu point for treating cold and snuffle |
| CN102188687A (en) * | 2011-05-11 | 2011-09-21 | 赵扬 | Traditional Chinese medicine composition for treating cold |
| CN102188687B (en) * | 2011-05-11 | 2013-02-13 | 赵杨 | Traditional Chinese medicine composition for treating cold |
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| CN102526671B (en) * | 2012-02-01 | 2013-12-11 | 李佳旺 | Traditional Chinese medicine composition for preventing and treating cough and cold and preparation method thereof |
| CN102526671A (en) * | 2012-02-01 | 2012-07-04 | 李佳旺 | Traditional Chinese medicine composition for preventing and treating cough and cold and preparation method thereof |
| CN102846920A (en) * | 2012-08-30 | 2013-01-02 | 李承平 | Ass-hide gelatin drug tablets with functions of lung reinforcing and heat clearing |
| CN103285267A (en) * | 2013-07-02 | 2013-09-11 | 宋宜德 | Drug for treating influenza and preparation method thereof |
| CN104127583A (en) * | 2014-06-20 | 2014-11-05 | 桂林浩新科技服务有限公司 | Cold-treating formula |
| CN104288401A (en) * | 2014-10-15 | 2015-01-21 | 雷雅斌 | Traditional Chinese medicine decoction for treating cough |
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| CN105168816A (en) * | 2015-10-26 | 2015-12-23 | 丁大位 | Traditional Chinese medicine decoction for treating cold and cough |
| CN107174649A (en) * | 2017-01-11 | 2017-09-19 | 李欣 | The cough mixture that old age can take for a long time |
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