CN1241396A - Spring ring technology and structure for embolus arterial tumor - Google Patents
Spring ring technology and structure for embolus arterial tumor Download PDFInfo
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- CN1241396A CN1241396A CN 99103275 CN99103275A CN1241396A CN 1241396 A CN1241396 A CN 1241396A CN 99103275 CN99103275 CN 99103275 CN 99103275 A CN99103275 A CN 99103275A CN 1241396 A CN1241396 A CN 1241396A
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- turn
- millimeter
- spring ring
- seal wire
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Abstract
The spring ring structure consists of special spring ring, circular spring ring, wire and adhering spot, and one end of the spring ring is adhered to the front end of the wire. It is manufactured through the steps of selecting spring wire, winding circular spring ring, making special spring ring by using specially shaped mold, heat treatment of spring ring to settle, making wire and adhering the spring ring and wire. The method of breaking and extricating the spring ring at arbitrary position is to connect the positive pole of constant current power supply to the end of the blocking spring ring and the negative pole to the stainless steel needle with the constant current strength being 2 mA. The present invention has no harmful side effect and can block completely arterial tumor of any shape for excellent treating effect.
Description
The present invention relates to technology and the structure of a kind of thromboembolism aneurysm, be mainly used in the usefulness of treatment aneurysm and other vascular malformation with turn.
Aneurysm be on tremulous pulse is grown for various reasons and the anomalous structure that forms, its tumor wall is compared with normal blood vessels, limited big defective.Under situations such as unexpected rising of blood pressure or arteriosclerosis, aneurysm can be broken, and causes fatal hemorrhage.
Past, can only take operation of opening cranium to aneurysm, close with metal aneurysm clamp 16 folders and see Fig. 9.
Prior art is that the Embolization that must not open cranium is seen Fig. 8, with tinsel 13 coiled coil component spring circles 14, fills up turn from putting into arterial vascular microtubular 7 toward aneurysm.Its weak point is: the structure of turn shape is single, is difficult to the aneurysm of different shape is full of fully, thereby influences therapeutic effect.Be the rustless steel welding between seal wire 2 and the turn, can not behind the filling turn, turn be disconnected any point except that this rustless steel solder joint 15 that cause the partial spring circle to be free in the parent artery, very easily secondary thrombus forms.
Thereby the objective of the invention is to overcome above-mentioned weak point of the prior art and provide a kind of clog fully and can arbitrarily disconnect turn obtain technology and the structure of the thromboembolism aneurysm of good therapeutic effect with turn.
Purpose of the present invention can reach by following measure: structure of the present invention is made of deformed spring circle, coil component spring circle, seal wire and adhesive spots, and turn is terminal and the seal wire front end is bonding.
The deformed spring circle is petal-shaped, dumbbell shaped, spindle shape and taper.
Adhesive spots is a conducting resinl.
Preparation process of the present invention is:
1, spring wire nitinol alloy wire composition, diameter and preparation.
(1) nitinol alloy wire composition (percentage by weight): nickel 50-65%, be preferably 58-62%, titanium 48-33% is preferably 40-36%;
(2) diameter 0.08-0.12 millimeter is preferably the 0.09-0.11 millimeter;
(3) preparation: use earlier the sand papering surface, with the suds flushing, clean with distilled water flushing at last then;
2, twine the coil component spring circle, use the spiral filament forming machine coiled, external diameter 0.12-0.35 millimeter is preferably the 0.17-0.30 millimeter, silk core 0.1 millimeter, spiral shell square 0.05-0.0476 millimeter.
3, prepare the deformed spring circle with petal-shaped, dumbbell shaped, spindle shape and taper mould, handle typing through thermal finalization, the external diameter of deformed spring circle is the 2.5-5 millimeter.
4, preparation seal wire.Cut-off directly is 0.25 millimeter nitinol alloy wire, is drawn into tapered seal wire in the high quartz stove, and nickel weight accounts for 55.6%, titanium accounts for 45%, the seal wire diameter is 0.26 millimeter 1300 millimeters of segment lengths, 200 millimeters of 0.15 millimeter segment lengths, 100 millimeters of 0.09 millimeter segment lengths.
5, seal wire head end 100 millimeters long surface gold-plating, 1300 millimeters long plating hydrophilic film.
6, bonding.With the NBCA conducting resinl that turn and seal wire head end is bonding.
Arbitrarily can the break desorption method of separating of turn of the present invention is:
In arteries, put into microtubular, choose stand-by turn and bonding seal wire, under X ray monitors, by microtubular turn is directed in the aneurysm, rear at the thromboembolism turn connects the constant current source positive pole, negative pole connects stainless pin, continuous current intensity 2mA, and the thromboembolism turn will rupture at the microtubular head end.
The drawing of accompanying drawing is described as follows:
Fig. 1 is the full aneurysmal total figure of thromboembolism of the present invention;
Fig. 2 is the axonometric chart of petal-shaped turn of the present invention;
Fig. 3 is the axonometric chart of dumbbell shaped turn of the present invention;
Fig. 4 is the axonometric chart of spindle shape turn of the present invention;
Fig. 5 is the axonometric chart of taper spring circle of the present invention;
Fig. 6 is the axonometric chart of coil component spring circle of the present invention;
Fig. 7 is the axonometric chart of turn of the present invention and the bonding back of seal wire (finished product);
Fig. 8 is the aneurysmal figure of prior art thromboembolism;
Fig. 9 closes aneurysmal figure for early stage technology with the aneurysm clamp folder.
The accompanying drawing piece number is represented:
1, deformed spring circle 2, lead 3, adhesive spots 4, arteries
5, aneurysm 6, end 7, microtubular 8, conducting resinl
9, petal-shaped turn 10, dumbbell shaped turn 11, spindle shape turn 12, taper spring circle
13, tinsel 14, coil component spring circle 15, rustless steel solder joint 16, aneurysm clamp
The invention will be further described below in conjunction with embodiment and accompanying drawing:
Fig. 1 represents the full aneurysmal structure of thromboembolism of the present invention.The present invention is made of coil component spring circle 14, deformed spring circle 1, seal wire 2 and adhesive spots 3.Because the shape of the aneurysm 5 that grows on the arteries 4 has nothing in common with each other, so, the shape of turn must be made shape as much as possible, just can reach and fill up various difform aneurysms fully effectively, to obtain curative effect as well as possible.The end 6 of turn must be connected with seal wire 2, and the present invention is that the conducting resinl 8 of usefulness is bonding.After the seal wire energising, adhesive spots can not disconnect, and any point except that adhesive spots all can disconnect.Like this, after filling up aneurysm, can disconnect, accomplish not make aneurysm to stay the broken end vestige of seal wire or spring wire outward, can not bring any adverse side effect behind the thromboembolism just exposing the neat root of aneurysmal seal wire.
The shape of Fig. 2,3,4, the various deformed spring circles of 5 expressions, Fig. 2 is a petal-shaped turn 9, and Fig. 3 is a dumbbell shaped turn 10, and Fig. 4 is a spindle shape turn 11, and Fig. 5 is a taper spring circle 12.
During use, in arteries, put into microtubular 7, get the deformed spring circle and the coil component spring circle of the prior art of coiling molding again ready, according to aneurysmal shape, choose stand-by turn, under the X-line monitors, turn and tumor inner spring circle are disconnected by microtubular.Embolus will forever be stayed body and function, and therefore aneurysm also reaches dissects the purpose of curing.
The manufacture method of the used turn of the present invention and processing step:
1, the composition of the used material of turn silk, diameter and preparation.
The composition of nitinol alloy wire (percentage by weight): nickel 50-65% is preferably 58-62%; Titanium 48-33% is preferably 40-36%; About oxygen 0.04%; Carbon 0.08%; Other are an amount of.Oxygen and carbon are to be difficult to the composition avoided in the preparation process.
The Nitinol filament diameter: the 0.08-0.12 millimeter is preferably the 0.09-0.11 millimeter.
The preparation method of nitinol alloy wire: use earlier the sand papering surface, then with the suds flushing, to remove surface and oil contaminant; Clean with distilled water flushing at last.
2, twine the coil component spring circle.Being wound in the coil component spring circle with spiral filament forming machine sees shown in Figure 6.Its external diameter is the 0.12-0.35 millimeter, is preferably the 0.17-0.30 millimeter; The silk core that forms its internal diameter is 0.1 millimeter; The spiral number of turns be 200-210 circle/centimetre, promptly the spiral shell square is the 0.05-0.0476 millimeter.Pull out a core behind the coiled.Choose no fracture of wire, unit's pine silk and do not have the silk section of folding firmly, carry out deuterostrophies and twine.
3, preparation deformed spring circle.The deformed spring circle that the present invention need prepare has petal-shaped to see that Fig. 2, dumbbell shaped see that Fig. 3, spindle shape see that Fig. 4 and taper see four kinds of Fig. 5, make the mould of above-mentioned four kinds of deformed spring circles earlier, with the coil component spring circle that wound on mould, handle through typing, the method for shaping that present embodiment adopts is the high-temperature shaping at quartzy stove 1400-1500 ℃.The external diameter of deformed spring circle is the 2.5-5 millimeter.After the molding of deformed spring circle, remove surface impurity, clean with distilled water flushing then, oven dry at last.
4, preparation seal wire.Choosing diameter is the common nitinol alloy wire of 0.25 millimeter, and nickel accounts for 55.6% (weight) and titanium accounts for 45%, is drawn into tapered seal wire in the high quartz stove, and total length is 1600 millimeters.Seal wire gradual change diameter and length are 1300 millimeters of 0.26 millimeter segment lengths of diameter, 200 millimeters of 0.15 millimeter segment lengths of diameter, 100 millimeters of 0.09 millimeter segment lengths of diameter.
5, the seal wire head end is gold-plated.In order to be increased in the marginal display resolution of X ray lower spring circle and seal wire,, carry out surperficial electrolytic gold plating at 100 millimeters of seal wire head ends (0.09 millimeter section of diameter) in order to avoid seal wire enters and punctures aneurysm in the aneurysm in the thromboembolism process.1300 millimeters at the seal wire back segment plate hydrophilic film.
6, bonding.Turn and seal wire head end is bonding, present embodiment α one cyano group acrylic acid fat (NBCA) conductive adhesive, this NBCA is a kind of biological adhesive.See Fig. 7 after finished product is made, put it in the 3F plastic catheter sealing and the sterilization back is preserved standby.
Arbitrarily can the break desorption method of separating of turn of the present invention:
After the thromboembolism turn put in place, its rear connect the constant current source positive pole, and negative pole connects stainless pin, continuous current intensity 2mA.Because principle of electrochemical reaction, turn will reach the thromboembolism purpose in the fracture of microtubular head end.The mechanism that electrochemistry is freed is the process of an electrochemical corrosion, has constituted basic galvanic element reaction on electrochemistry, and the process of electrochemical corrosion is called anodic solution.Turn serves as anode in this electrochemical reaction process.
The process of electrochemical corrosion is accompanied by the transfer of metal ion, and this process also is an oxidation reaction process.Metallic atom is decomposed into metal ion and electronics in the reaction, can be decomposed into one mole metal M as one mole metal M
N+With the electronics of n mole, under the constant function of current, this electrochemical reaction constantly and finally causes anodic solution.
Electrochemical corrosion has two kinds of homogeneous corrosion and local corrosions, involved in the present invention to corrosion belong to local corrosion.This is different the causing of concentration owing to dissolved oxygen in the medium.According to the Nenst formula when in anode the is in different medium on two different interface interface points electromotive force the highest.Suppose to serve as anodic metal at other surperficial uniformities, it is the fastest and finally cause anode metal in the fracture of this point that oxidation reaction will constantly take place on different interface point so.If its surface of anode metal is inhomogeneous, and there is impurity to adhere to, will forms a plurality of difference in oxygen concentration between batteries, and cause anode metal many places corrosion and fracture to occur at these impurity or inhomogeneous place.
The present invention contrasts prior art and has following advantage:
Can disconnect in any point, avoid any bad side effect; To the aneurysm of any shape, all can accomplish Filling is complete, to obtain good result for the treatment of.
Claims (4)
1, a kind of thromboembolism aneurysm is characterized in that with the structure of turn, is made of deformed spring circle, coil component spring circle, seal wire and adhesive spots, and turn is terminal and the seal wire front end is bonding.
2, thromboembolism aneurysm according to claim 1 is characterized in that with the structure of turn the deformed spring circle is petal-shaped, dumbbell shaped, spindle shape and taper.
3, thromboembolism aneurysm according to claim 1 is characterized in that with the structure of turn adhesive spots is a conducting resinl.
4, a kind of thromboembolism aneurysm is characterized in that with the preparation process of turn,
(1), spring wire nitinol alloy wire composition, diameter and preparation,
1. nitinol alloy wire composition (percentage by weight), nickel 50-65% is preferably 58-62%, and titanium 48-33% is preferably 40-36%,
2. diameter 0.08-0.12 millimeter is preferably the 0.09-0.11 millimeter,
3. the sand papering surface is used earlier in preparation, and is with the suds flushing, clean with distilled water flushing at last then,
(2), twine the coil component spring circle, use the spiral filament forming machine coiled, external diameter 0.12-0.35 millimeter is preferably the 0.17-0.30 millimeter, core 0.1 millimeter, spiral shell square 0.05-0.0476 millimeter,
(3), prepare the deformed spring circle, handle typing through thermal finalization, the external diameter of deformed spring circle is the 2.5-5 millimeter with petal-shaped, dumbbell shaped, spindle shape and taper mould,
(4), the preparation seal wire, cut-off directly is 0.25 millimeter nitinol alloy wire, is drawn into tapered seal wire in the high quartz stove, nickel weight accounts for 55.6%, and titanium accounts for 45%, and the seal wire diameter is 0.26 millimeter 1300 millimeters of segment lengths, 0.15 200 millimeters of segment lengths of millimeter, 100 millimeters of 0.09 millimeter segment lengths
(5), seal wire head end 100 millimeters long surface gold-plating, 1300 millimeters long platings hydrophilic film,
(6), bonding turn and seal wire head end is bonding with the NBCA conducting resinl,
The thromboembolism aneurysm with arbitrarily can the break desorption method of separating of turn of turn is
In arteries, put into microtubular, choose stand-by turn and bonding seal wire, under X ray monitors, by microtubular turn is directed in the aneurysm, rear at the thromboembolism turn connects the constant current source positive pole, negative pole connects stainless pin, continuous current intensity 2mA, and the thromboembolism turn will rupture at the microtubular head end.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99103275 CN1241396A (en) | 1999-03-30 | 1999-03-30 | Spring ring technology and structure for embolus arterial tumor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 99103275 CN1241396A (en) | 1999-03-30 | 1999-03-30 | Spring ring technology and structure for embolus arterial tumor |
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| CN1241396A true CN1241396A (en) | 2000-01-19 |
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| CN 99103275 Pending CN1241396A (en) | 1999-03-30 | 1999-03-30 | Spring ring technology and structure for embolus arterial tumor |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103025270A (en) * | 2010-06-07 | 2013-04-03 | 库克医药技术有限责任公司 | Reperfusion catheter system |
| CN103381281A (en) * | 2013-04-27 | 2013-11-06 | 王东 | Medical guide wire |
| CN106725697A (en) * | 2017-03-03 | 2017-05-31 | 王奎重 | A kind of multiple spot for freeing embolism materials is electrolysed de- system and solution desorption method |
| CN111491575A (en) * | 2018-12-17 | 2020-08-04 | 柯惠有限合伙公司 | Devices, systems, and methods for treating vascular defects |
| CN117045303A (en) * | 2023-08-16 | 2023-11-14 | 南京思脉德医疗科技有限公司 | Wire changing device of embolic coil conveying system |
-
1999
- 1999-03-30 CN CN 99103275 patent/CN1241396A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103025270A (en) * | 2010-06-07 | 2013-04-03 | 库克医药技术有限责任公司 | Reperfusion catheter system |
| CN103381281A (en) * | 2013-04-27 | 2013-11-06 | 王东 | Medical guide wire |
| CN106725697A (en) * | 2017-03-03 | 2017-05-31 | 王奎重 | A kind of multiple spot for freeing embolism materials is electrolysed de- system and solution desorption method |
| CN106725697B (en) * | 2017-03-03 | 2023-07-14 | 上海微密医疗科技有限公司 | Multi-point electrolytic stripping system for stripping embolic material |
| CN111491575A (en) * | 2018-12-17 | 2020-08-04 | 柯惠有限合伙公司 | Devices, systems, and methods for treating vascular defects |
| CN117045303A (en) * | 2023-08-16 | 2023-11-14 | 南京思脉德医疗科技有限公司 | Wire changing device of embolic coil conveying system |
| CN117045303B (en) * | 2023-08-16 | 2024-02-02 | 南京思脉德医疗科技有限公司 | Wire changing device of embolic coil conveying system |
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