CN1235521C - Improved delivery of benefit agents - Google Patents
Improved delivery of benefit agents Download PDFInfo
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- CN1235521C CN1235521C CNB028077954A CN02807795A CN1235521C CN 1235521 C CN1235521 C CN 1235521C CN B028077954 A CNB028077954 A CN B028077954A CN 02807795 A CN02807795 A CN 02807795A CN 1235521 C CN1235521 C CN 1235521C
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- food additives
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- nuclear core
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/40—Table salts; Dietetic salt substitutes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
- A23L27/72—Encapsulation
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
- A23P10/00—Shaping or working of foodstuffs characterised by the products
- A23P10/30—Encapsulation of particles, e.g. foodstuff additives
- A23P10/35—Encapsulation of particles, e.g. foodstuff additives with oils, lipids, monoglycerides or diglycerides
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Preparation And Processing Of Foods (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention provides a substantially encapsulated food additive particle comprising: a) an inorganic, porous core in which one or more water-soluble functional ingredients are impregnated, and b) a hydrophobic, water-insoluble outer coating having a melting point of greater than 100oC and comprising one or more multivalent metal salts of fatty acids of chain length not less than 8.The particles exhibit good resistance to degradation in food articles, upon storage and during cooking but breakdown after consumption to make the functional ingredients bio-available to the body. A method of making the particles and food articles comprising the same are also provided.
Description
Technical field
The functional component that the present invention relates to seal basically, the food function composition of particularly sealing the invention still further relates to the preparation method of these functional components.
Background of invention
Often known with the functional component coating or seal in the prior art.Do so often is in order to reduce between this composition and the product during adding or in the disadvantageous interaction of product processing or lay up period.Do the performance that to give heat resistanceheat resistant, pH and/or moisture like this.Sealing or being coated with also provides control or has targetedly discharged this composition.The example of these functional components has spices, pigment, dyestuff, flavouring agent, vitamin and food function composition.
Several coating known in the art or the method for sealing.They comprise physico-chemical process, for example interfacial polymerization, cohesion, with moisture or organic solvent be separated, form fusible dispersion, then be coated with and solidify, and the mechanical means that comprises spray-drying and vacuum coated.Require this coating enough hard tolerating chemistry and physical damnification, and under appropraite condition, also decompose functional component contained in the release coat.
At Microcapsule Processing and Technology, A.Kondo, editor and revision J.W van Valkenburg, Marcel Dekker, New York and Basel provide the deep description of coating and encapsulating method in 1979.
Coating material can be water miscible or water-insoluble.The example of water soluble paint comprises cellulose, hydroxyethylcellulose, gelatin, casein, dextrin and CMS.The water-insoluble coating material comprises the alkali salt of silicate, clay and aliphatic acid.
Yet, often preferably this functional component is distributed in the nuclear core material, then this nuclear core is coated with or seals.Conventional nuclear core material is the gel that is dispersed with functional component.The example of this nuclear core material has methylcellulose and gelatin.Also disclose the inorganic material of porous in the prior art, for example silica and zeolite are as the nuclear core material.Especially, VOC such as flavouring agent and spices and reactive compounds such as bleaching agent can be distributed in the hole of inorganic material, and only can utilize during use.
Often functional food composition is joined in food or the goods as containing iodine compound and vitamin.Yet these functional food compositions are under some cooking conditions and at the lay up period potentially unstable.For example, contain iodine compound, as Potassiumiodate, at acid pH and having under the situation of reducing agent (for example used spices of cooking period) and be reduced to elemental iodine.Therefore their difficult desired forms with utilization are the human body utilization.
Other functional food composition, for example iron compound and oligopeptides are in the time of in joining food article, usually at lay up period or produce undesirable color or undesirable sense quality during use.Therefore they before adding through sealing, so that they are not useful with other component interaction and the organoleptic properties that influences food article or other composition unfriendly.
US 4 671 963 discloses the food that is coated with stearic alkali salt.Having under the situation of moisture, this water-insoluble coating helps to keep the initial quality of coat foods.The preferred embodiment of this food is crisp food such as grain strip rod.Zinc stearate, calcium stearate or dolomol are dissolved in the tristearin, then it are coated on the cereal.Also these stearate powder can be sprinkling upon on the oleaginous grains so that a waterproof coating to be provided.
The method that contains iodine compound of sealing is disclosed in indian patent IN 182558 and IN 182559.Disclose and to have used many materials to give to contain iodine compound that one protective finish is provided and this encapsulated particles can be joined in the salt.
US 6 030 645 discloses the oleophilic substance that comprises in the matrix that is scattered at least a nuclear core material and the particle of coating.This oleophilic substance is vitamin A or E.The nuclear core material is gel and can be selected from cellulose and derivative, alginic acid and derivative thereof, sugar and sugar alcohol and glycerine.Coating material is water-insoluble and comprises calcium silicates.Also magnesium silicate, silica, calcium stearate or dolomol can be joined in this coating.
EP-A-675 194 discloses the liquid detergent composition that contains encapsulated particles.This detergent active is adsorbed on the porous hydrophobic material of hydrophobic silica for example, further with hydrophobic compound such as silicone oil it is coated with then.
WO98/42818 discloses the laundry functional component particle that is used to discharge spices and contains the zeolite porous carrier nuclear core that is mixed with glassy encapsulating material, described glassy encapsulating material is the compound of the water-soluble or water dispersible of part, and it especially can be selected from water-soluble polymer, carbohydrate, cellulose and wax.
WO 97/48386 discloses the agent of a kind of compacting nuclear chip, and it contains Diltiazem (active component), cataloid and the dolomol of therapeutic dose.
Heat, moisture and pH sensitiveness functional component (for example Potassiumiodate and vitamin) be in joining food article the time, storing and/or its concentration of cooking period reduces greatly and even loses, and also be known.Therefore edible when containing the food of this functional component, they are difficult for or can not be utilized by human body reliably.
The known packets encapsulation method that uses aspect food article does not guarantee that coating is heat-resisting, moisture and pH, and guarantees that the functional component of sealing is easy to by the human body utilization to gratifying degree.
Therefore, need provide and to join in the food article and enough stable so that can easily be the functional component of human body utilization after edible to gratifying degree.
In addition, known some functional component such as iron containing compounds and oligopeptides have side effect to the organoleptic properties of food.This may be because functional component and other component interaction that is present in the food.Therefore, need provide such composition, they are in preparation, storage or do not give the undesirable color of food or undesirable sensory property between the operating period.
The present invention seeks to solve above-mentioned one or more problems.
Summary of the invention
We unexpectedly find, top problem can be according to the present invention, solve by the free flowing granule that contains following material: the i) inorganic porous material of infiltration water-solubility function composition and ii) contain the water-insoluble heat endurance external coating of the multivalent metal salt of one or more aliphatic acid.This external coating decomposes the release function composition in digestion process, thereby is the health biological utilisation.Particle by this method preparation can join in food or the goods.
Therefore, the invention provides new encapsulated particles, it contains functional component, in food.
We find that also these particles can make by method as herein described, thereby make the stable encapsulated particles of only decomposing under low pH.
Unsettled functional component between storage and operating period perhaps with the interactional unfriendly functional component of other food component, can use method of the present invention suitably to seal.
Therefore, according to a first aspect of the invention, provide a kind of food additives particle of sealing basically, it comprises:
A) infiltrate one or more water-solubility function compositions inorganic porous nuclear core and
B) has fusing point greater than 100 ℃ and comprise that one or more chain lengths are not less than the hydrophobic water-insoluble external coating of the multivalent metal salt of 8 aliphatic acid.
According to a second aspect of the invention, provide a kind of preparation method of the food additives particle of sealing basically, the method comprising the steps of:
A) aqueous solution with the water-solubility function composition joins in the inorganic porous material, and the pore volume that makes this solution occupy porous nuclear core material is no more than 90%, thus form an infiltration nuclear core and
B) randomly should infiltrate nuclear the core drying and
C) form the hydrophobic water-insoluble external coating that one or more chain lengths are not less than the multivalent metal salt of 8 aliphatic acid on this infiltration nuclear core, wherein this coating has the fusing point greater than 100 ℃.
According to a third aspect of the present invention, provide a kind of food of cooperative reinforcing, it contains the food additives particle of sealing basically of the present invention.
A kind of particularly preferred enriched food is to strengthen salt, and it also contains with Potassiumiodate or the KI food additives particle of sealing basically of the present invention as the water-solubility function composition.
The example of water-solubility function composition is to contain iodine compound, iron containing compounds, vitamin C, carotenoid and oligopeptides.
One or more the advantage that provides in following is provided in the present invention:
A) join functional component in the food in processing, storage and the stability between the operating period,
B) in the stability that functional component under the situation of reducing agent is arranged,
C) waterproof of functional component, heat resistanceheat resistant and anti-pH performance, and/or
D) coating of the present invention in digestive system, decompose make the functional component that joins in the food be easier to into the human body utilization with bio-absorbable.
Encapsulated particles of the present invention is also separated functional component with other component of food, compare with the organoleptic properties of using the non-identical function composition of sealing to obtain thus, has significantly improved the organoleptic properties of this food.
Except in operation and comparative example, outside perhaps explaining in addition, all numerical value of the physical property of indication material quantity or reaction condition, material and/or purposes all are interpreted as modifying with word " pact " in this specification.All are measured all by weight, except as otherwise noted.
Detailed Description Of The Invention
Discuss form of the present invention now in more detail, comprise preferred and optional feature, and operable material.
Term used herein " encapsulated particles " is meant the food additives particle of sealing basically of the present invention.
Encapsulated particles
Encapsulated particles comprises dispersion (infiltration) one or more functional components in the inorganic porous nuclear core.This porous nuclear core is hydrophilic in nature preferably.
This inorganic porous nuclear core is referred to as porous nuclear core hereinafter, and the porous nuclear core that contains one or more functional components is referred to as infiltration nuclear core below.
Infiltration nuclear core also is coated with the multivalent metal salt (this paper back is referred to as external coating) of one or more aliphatic acid.Inorganic porous nuclear core and external coating are preferably with 1: 0.1-1: 10, more preferably 1: 0.2-1: 5, most preferably 1: 0.2-1: 3 weight ratio exists.
It is necessary that external coating is sealed infiltration nuclear core basically.
The particle diameter of encapsulated particles is the 0.1-100 micron preferably, is more preferably the 0.5-80 micron, most preferably is the 1-50 micron.
Coating or encapsulating method
Join in the inorganic porous material by the aqueous solution, porous is examined core infiltrate with one or more water-solubility function compositions with functional component.Preferred adding method is by being sprayed on this aqueous solution, perhaps by on the stirring powder that it is added drop-wise to inorganic porous material.
The aqueous solution of preferred function composition joins on the inorganic porous material with progressive mode, thereby prevents the inorganic porous material gathering.The aqueous solution occupies the pore volume of examining core material and is no more than 90% during the preparation.The pore volume that occupies can reduce in time, for example when by dry or remove when anhydrating by handling with suitable solvent.
The nuclear core that infiltrated can be chosen wantonly through super-dry to remove the water in the hole.But also can be distributed to the water soluble functional component and can not be dissolved in the water of removing in wherein the solvent in the hole by the nuclear core that will infiltrate.
The infiltration nuclear core needs that form further are coated with the multivalent metal salt of one or more aliphatic acid.This coating can for example provide by several method as described below.
A kind of method for optimizing that obtains coating be at first will infiltrate nuclear core join in the mixture of multivalent metal hydroxides, polyvalent metal halide and suitable solvent.In this mixture, add chain length then and be not less than the molten mass of one or more aliphatic acid of 8, produce the water-insoluble external coating of infiltration nuclear core.This external coating forms by producing one or more fatty acid metal salts on the spot and it being deposited on the infiltration nuclear core.After forming coating, can solvent be removed by any appropriate method.According to this method for optimizing, the pH of the mixture of multivalent metal hydroxides, polyvalent metal halide and solvent is necessary in the 8-10.5 scope.Bound by theory not it is believed that essential this buffering is to keep the desired structure of infiltration nuclear core.More preferably this pH scope is at 9-10.5, most preferably at 9.9-10.3.
Calcium hydroxide and magnesium hydroxide are particularly preferred multivalent metal hydroxides.Calcium chloride and magnesium chloride are particularly preferred polyvalent metal halide.Polyvalent metal halide is preferably with the 35-50% of multivalent metal hydroxides weight, and more preferably the amount with the 39-42% of alkaline earth metal hydroxide weight exists.
Solvent should have moderate dielectric constant, should not dissolve to be present in the functional component in the infiltration nuclear core and to answer dissolved fat acid.The example of this solvent is C
1-C
6Chain alcohol.Ethanol is particularly preferred solvent.
Bound by theory not it is believed that this solvent can dissociate aliphatic acid and metal hydroxides, thereby forms soap.
In a kind of typical method, infiltration nuclear core is joined in the mixture of multivalent metal hydroxides, polyvalent metal halide and solvent and stir.This dispersion is joined in one or more aliphatic acid of fusion then.Requirement is with the mixture continuous stirring.The temperature of reactant mixture is 60-75 ℃, is more preferably 65-75 ℃.Incorporation time is unimportant, but preferred this time is at least 10 minutes.On infiltration nuclear core, carry out the precipitation on the spot of soap, the particle of being sealed basically.
Can solvent be removed by any conventional method dry or evaporation, and can recycle.
Knownly in this area can not seal fully usually.Therefore method of the present invention provides the porous nuclear of sealing basically core.
Functional component
The amount of functional component in porous nuclear core be the 0.1-60 weight % of porous nuclear core weight preferably, is more preferably 1-30%, most preferably is 5-20%.
Functional component is present in the hole of inorganic porous material.
When functional component is when containing iodine compound, it is preferably selected from alkaline metal iodide or iodate or its mixture.Preferred especially Potassiumiodate and KI and composition thereof.
Be applicable to that the iron compound of sealing comprises ferrous sulfate, ferrous gluconate and ferrous fumarate and iron-amino acid complex such as ferrous sulfate-glycine.
Vitamin C and precursor thereof, carotenoid and oligopeptides also are the suitable water-solubility function compositions that can seal by the inventive method.Contain and be lower than 10 amino acid whose peptides and be called oligopeptides.
Porous nuclear core
Porous nuclear core is inorganic, water-insoluble and hydrophilic in nature.Its selection makes the average pore size of its average pore size greater than the hydration ball of functional component or its disassociation ion.Pore volume is enough big, to comprise the aqueous solution of functional component.
Porous nuclear core preferably make by being selected from by one or more material in silica, silicate and the alumino-silicate.Silica is preferred material, and preferably exists with the form of amorphous silica.Silicate comprises alkali metal and alkaline-earth-metal silicate.Alumino-silicate comprises zeolite.Amorphous silica is a kind of particularly preferred nuclear core material.
The particle diameter of inorganic porous nuclear core is the 0.1-50 micron preferably, is more preferably the 0.2-25 micron, most preferably is the 0.5-10 micron.
The aperture in the hole of porous nuclear core is 0.1-500nm preferably, is more preferably 0.4-100nm, most preferably is 0.5-50nm.
The pore volume of porous nuclear core is 2-5.5ml/g preferably, is more preferably 2.5-2.8ml/g.
External coating
External coating is hydrophobic, water insoluble, and has the fusing point greater than 100 ℃.External coating comprises that one or more chain lengths are not less than the multivalent metal salt of 8 aliphatic acid.More preferably external coating is one or more multivalent metal salt, particularly calcium salt or the magnesium salts in stearic acid, palmitic acid and the myristic acid.Most preferably external coating comprises stearic calcium salt.
When using the mixture of aliphatic acid, each aliphatic acid of any ratio be can use, and the stability and the water-insoluble of external coating do not influenced, condition is that the fusing point of external coating is greater than 100 ℃.
Preferably 0.003 micron-1 micron of the thickness of external coating is more preferably 0.01 micron-0.8 micron, most preferably is the 0.1-0.5 micron.
External coating is at pH4.0 and above stable.
PH in the stomach changes between 0.9-3.0 usually.Therefore the external coating through the wrapped and sealed food additive granules of digestion will decompose in digestion process, and functional component will be examined core from porous and discharge.
Encapsulated particles is joined in the food
Encapsulated particles of the present invention can join in the food (goods).The example of these foods comprises salt, beverage, comprises the flour of wheat flour, fruit juice, cereal etc.
Further describe the present invention by following non-limiting example, wherein part and percentage all are by weight, except as otherwise noted.Other embodiment within the scope of the invention will be conspicuous to those skilled in the art.
Embodiment
The comparative example A
Under 25 ℃, 18ml Potassiumiodate (from E.Merck (I) Ltd.) aqueous solution is slowly joined the drying precipitated silica of 10g (deriving from Madhu Silica Pvt.Ltd., India), and continuous stirring 30 minutes.When finishing, this process reclaims infiltration nuclear core with dry powder form.By its average grain diameter of Zeiss measurement microscope, and be found to be the 4-15 micron.By the total iodate content of iodometric determination, discovery is 8 weight % (silica relatively).
Comparative Examples B
The 8g Potassiumiodate is joined in the mixture (deriving from LobaChemie, Mumbai, India) of fusion stearic acid and palmitic acid.Stearic acid is 55: 45 to the weight ratio of palmitic acid.Molten fat acid remains on 75 ℃.Mixture is stirred, then it is cooled to laboratory temperature.Average grain diameter by the Zeiss measurement microscope is the 50-200 micron, and the total iodate content by iodometric determination is 8 weight % (calcium stearates relatively).
Embodiment 1
The preparation method of encapsulated particles
A. the preparation method of core is examined in infiltration
In 30 minutes, 18ml Potassiumiodate (deriving from E.Merck (I) Ltd.) aqueous solution is slowly joined in the drying precipitated silica of 8g (deriving from Madhu Silica Pvt.Ltd., India) under 25 ℃.During adding with the mixture continuous stirring.When finishing, this process reclaims infiltration nuclear core with dry powder form.
B. the preparation method of encapsulated particles
2.15g calcium chloride is joined formation one homogeneous solution in the ethanol.Further this solution is joined in the alcoholic dispersion of calcium hydroxide.The pH that stirs the mixture is 10.3.To contain KIO
3Infiltration nuclear core join in this alcoholic dispersion.PH does not have marked change.
The alcoholic dispersion that will contain infiltration nuclear core is poured in 24g fusion stearic acid and the palmitic acid (deriving from Loba Chemie, Mumbai, India).Stearic acid is 55: 45 with the ratio of palmitic acid.Mixture remains on 75 ℃ and continuous stirring.Then it is cooled to laboratory temperature.Remove by filter excess ethanol.Obtain encapsulated particles, be free-pouring powder, average grain diameter is 5 microns.Total iodate content in the encapsulated particles is 3.3 weight %.
Stability in the water of room temperature and boiling temperature
Measure the stability of encapsulated particles in water and the ability of reservation iodate thereof.
In first test, the material of embodiment 1 was stirred in water 30 minutes.Then this dispersion is filtered, by the amount of Potassiumiodate in the iodometric determination filtrate.Comparative example A and B are repeated this step.
In second test, the material of embodiment 1 is dispersed in the water, and the temperature of water is risen to boiling temperature.Boiling is 30 minutes continuously.Then dispersion is filtered, by the amount of Potassiumiodate in the iodometric determination filtrate.Comparative example A and B are repeated this step.
The following expression of the Potassiumiodate that keeps in the particle:
Iodate %=(the I that particle keeps
Always-I
Filtrate)/I
Always* 100 I wherein
AlwaysBe the total iodate content in the particle, I
FiltrateBe the iodate content in the water (after the filtration).The results are shown in table 1.
Table 1: Potassiumiodate retention
| Embodiment | The iodate % that keeps in the particle | |
| Water (room temperature) | Water (boiling temperature) | |
| A | ?0 | ?0 |
| B | ?25 | ?20 |
| Embodiment 1 | ?89 | ?89 |
Data in the table 1 have shown uses encapsulated particles of the present invention to keep most of iodate.
Absolute acid stability
The stability of mensuration particle under cooking pH condition and under gastric ph conditions.
In order to be determined at the stability under the cooking pH condition, the material of embodiment 1 to be scattered in the water, and the pH of dispersion is adjusted to 4.2.Dispersion is boiled 30 minutes then.With the dispersion cooling, filter and pass through the Potassiumiodate content of iodometric determination filtrate then.Comparative example A and Comparative Examples B are repeated this step.
In order to be determined at the stability under the gastric ph conditions, the material of embodiment 1 is scattered in the 0.33N hydrochloric acid solution, this mixture was stirred 30 minutes.Dispersion is filtered, and pass through the Potassiumiodate content of iodometric determination filtrate.Comparative example A and Comparative Examples B are repeated this step.Percentage as iodate in the particle after the mensuration processing of explaining above.Data are shown in table 2.
Table 2: the stability under acid condition
| Embodiment | The iodate % that keeps in the particle | |
| Cooking pH | Stomach pH | |
| ?A | ?0 | ?0 |
| ?B | ?15 | ?0 |
| Embodiment 1 | ?75 | ?1.5 |
These data show that encapsulated particles of the present invention is stable under cooking pH, but decompose under stomach pH, discharge iodate.Therefore encapsulated particles of the present invention is stable under normal cooking conditions, and has prevented iodate loss or decomposition at cooking period.Yet it decomposes and therefore can make this iodate biological utilisation under gastric ph conditions, is absorption of human body.
Claims (31)
1. food additives particle of sealing basically comprises:
A) wherein infiltrate one or more water-solubility function compositions inorganic porous nuclear core and
B) fusing point is greater than 100 ℃ and comprise that one or more chain lengths are not less than the hydrophobic water-insoluble external coating of the multivalent metal salt of 8 aliphatic acid, and the weight ratio of wherein inorganic porous nuclear core and external coating is 1: 0.1-1: 10.
2. food additives particle as claimed in claim 1, wherein said weight ratio is 1: 0.2-1: 5.
3. as the food additives particle of claim 1 or 2, has the particle diameter of 0.1-100 micron.
4. food additives particle as claimed in claim 3 has the particle diameter of 0.5-80 micron.
5. as each food additives particle of front claim, the particle diameter of wherein inorganic porous nuclear core is the 0.1-50 micron.
6. food additives particle as claimed in claim 5, wherein the particle diameter of porous nuclear core is the 0.2-25 micron.
7. food additives particle as claimed in claim 1, wherein inorganic porous nuclear core has the hole that diameter is 0.1-500nm.
8. food additives particle as claimed in claim 7, wherein said hole has the aperture of 0.4-100nm.
9. food additives particle as claimed in claim 1, wherein the pore volume of porous nuclear core is 2-5.5ml/g.
10. food additives particle as claimed in claim 9, its mesopore volume is 2.5-2.8ml/g.
11. food additives particle as claimed in claim 1, wherein the thickness of external coating is the 0.003-1 micron.
12. as the food additives particle of claim 11, wherein the thickness of external coating is the 0.01-0.8 micron.
13. food additives particle as claimed in claim 1, wherein inorganic porous nuclear core is to be made by the material that is selected from silica, silicate and alumino-silicate.
14. as the food additives particle of claim 13, wherein said material is a silica.
15. as the food additives particle of claim 14, wherein said material is an amorphous silica.
16. food additives particle as claimed in claim 1, wherein external coating comprises the calcium salt or the magnesium salts of stearic acid, palmitic acid and/or myristic acid.
17. as the food additives particle of claim 16, wherein external coating comprises stearic calcium salt.
18. food additives particle as claimed in claim 1, wherein the amount of water-solubility function composition is the 0.1-60 weight % of inorganic porous nuclear core weight.
19. as the food additives particle of claim 18, wherein the amount of water-solubility function composition is 1-30 weight %.
20. food additives particle as claimed in claim 1, wherein the water-solubility function composition is selected from and contains iodine compound, iron containing compounds, vitamin C, carotenoid and oligopeptides.
21. as the food additives particle of claim 20, wherein the water-solubility function composition is Potassiumiodate or KI.
22. the preparation method of a food additives particle of sealing basically, the method comprising the steps of:
A) aqueous solution with the water-solubility function composition joins in the inorganic porous nuclear core material, and the pore volume that makes this solution occupy porous nuclear core material is no more than 90%, thus form infiltration nuclear core and
B) optional should infiltrate examine the core drying and
C) on this infiltration nuclear core, form the hydrophobic water-insoluble external coating that one or more chain lengths are not less than the multivalent metal salt of 8 aliphatic acid, wherein this coating has the fusing point greater than 100 ℃, and the weight ratio of wherein inorganic porous nuclear core and external coating is 1: 0.1-1: 10.
23. method as claim 22, wherein external coating is to form like this: the nuclear core that will infiltrate joins in the mixture of multivalent metal hydroxides, polyvalent metal halide and solvent, this mixture has the pH of 8-10.5, one or more chain lengths of adding fusion are not less than 8 aliphatic acid and after forming coating solvent are removed.
24. as the method for claim 23, the pH of wherein said mixture is 9-10.5.
25. as the method for claim 23 or 24, wherein multivalent metal hydroxides is calcium hydroxide or magnesium hydroxide, polyvalent metal halide is calcium chloride or magnesium chloride.
26. as the method for claim 23 or 24, wherein polyvalent metal halide exists with the amount of the 35-50 weight % of multivalent metal hydroxides weight.
27. as the method for claim 26, wherein polyvalent metal halide exists with the amount of 39-42 weight %.
28. as the method for claim 22, wherein solvent is C
1-C
6Chain alcohol.
29. as the method for claim 28, wherein solvent is an ethanol.
30. a condensed food contains each the food additives particle of sealing basically of claim 1-21.
31. condensed food, wherein this food is to strengthen salt, it contains each the food additives particle of sealing basically of claim 1-21, described particle is prepared from by the method for claim 22, and the water-solubility function composition in the food additives particle of wherein sealing basically is acid iodide first or KI.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN310/MUM/2001 | 2001-04-03 | ||
| IN310MU2001 | 2001-04-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1501778A CN1501778A (en) | 2004-06-02 |
| CN1235521C true CN1235521C (en) | 2006-01-11 |
Family
ID=11097231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB028077954A Expired - Fee Related CN1235521C (en) | 2001-04-03 | 2002-03-08 | Improved delivery of benefit agents |
Country Status (7)
| Country | Link |
|---|---|
| CN (1) | CN1235521C (en) |
| AP (1) | AP1716A (en) |
| AU (1) | AU2002240942A1 (en) |
| BR (1) | BR0208644A (en) |
| MX (1) | MXPA03009014A (en) |
| WO (1) | WO2002080706A2 (en) |
| ZA (1) | ZA200306781B (en) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2664585C (en) | 2006-09-27 | 2015-04-14 | Conagra Foods Rdm, Inc. | Seasoning and method for enhancing and potentiating food flavor utilizing microencapsulation while reducing dietary sodium intake |
| JP5791304B2 (en) * | 2011-02-17 | 2015-10-07 | アサヒフードアンドヘルスケア株式会社 | Vitamin C reaction suppression method and food products containing vitamin C |
| JP5948089B2 (en) * | 2012-03-02 | 2016-07-06 | アサヒフードアンドヘルスケア株式会社 | Vitamin mineral-containing tablet and method for producing the same |
| US20140272012A1 (en) * | 2013-03-15 | 2014-09-18 | J.M. Huber Corporation | Silica Based Salt Solution Delivery System |
| IT201600129738A1 (en) * | 2016-12-22 | 2018-06-22 | Perprin S R L | PROTECTIVE AGENT FOR FOOD AND SIMILAR PRODUCTS AND FOR SEASONING AND STORAGE ENVIRONMENTS |
| PL3723504T3 (en) | 2017-12-14 | 2022-06-06 | Venta De Especialidades Químicas S.A. | Food-grade coated particles containing polycarboxylic acids |
| US20210015135A1 (en) | 2018-03-29 | 2021-01-21 | Tata Chemicals Limited | Encapsulated micronutrient granules for fortification of edible salt compositions |
| WO2019243869A1 (en) * | 2018-06-19 | 2019-12-26 | Perprin S.R.L. | Protective agent for food products and the like and for curing and/or storage rooms of the same |
| GB201911105D0 (en) * | 2019-08-02 | 2019-09-18 | Governing Council Of The Univ Of Toronto | Multi-supplement food-additive |
| BR112022006149A2 (en) | 2019-10-16 | 2022-06-28 | Symrise Ag | ARTICLES FOR INDIRECT TRANSFER OF COSMETIC ACTIVE COMPOUNDS FOR SKIN |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2550015A (en) * | 1948-11-15 | 1951-04-24 | Iowa Limestone Company | Method of preventing loss of iodine from iodine in the elementary state and all of its compounds |
| DE3409063A1 (en) * | 1984-03-13 | 1985-09-19 | Basf Ag, 6700 Ludwigshafen | METHOD FOR PRODUCING FLOWABLE CHOLIN CHLORIDE-SILICONE POWDER |
| FR2631620B1 (en) * | 1988-05-19 | 1990-07-27 | Rhone Poulenc Chimie | NOVEL PRECIPITATED ABSORBENT SILICA AND COMPOSITION BASED ON SAILOR |
| GB9418752D0 (en) * | 1994-09-16 | 1994-11-02 | Ici Plc | Animal feedstuffs and additives |
| JP3919840B2 (en) * | 1995-12-28 | 2007-05-30 | 武田薬品工業株式会社 | Pharmaceutical composition |
-
2002
- 2002-03-08 CN CNB028077954A patent/CN1235521C/en not_active Expired - Fee Related
- 2002-03-08 AU AU2002240942A patent/AU2002240942A1/en not_active Abandoned
- 2002-03-08 WO PCT/EP2002/002603 patent/WO2002080706A2/en not_active Application Discontinuation
- 2002-03-08 MX MXPA03009014A patent/MXPA03009014A/en active IP Right Grant
- 2002-03-08 AP APAP/P/2003/002866A patent/AP1716A/en active
- 2002-03-08 BR BR0208644-1A patent/BR0208644A/en not_active IP Right Cessation
-
2003
- 2003-08-29 ZA ZA200306781A patent/ZA200306781B/en unknown
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|---|---|
| AP1716A (en) | 2007-01-26 |
| ZA200306781B (en) | 2004-08-30 |
| CN1501778A (en) | 2004-06-02 |
| AP2003002866A0 (en) | 2003-09-30 |
| WO2002080706A3 (en) | 2003-02-06 |
| BR0208644A (en) | 2004-03-02 |
| WO2002080706A2 (en) | 2002-10-17 |
| MXPA03009014A (en) | 2004-02-12 |
| AU2002240942A1 (en) | 2002-10-21 |
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