CN1234384C - Chinese medicinal preparation for preventing and curing enteric disease of animal and paultory and its preparation method - Google Patents
Chinese medicinal preparation for preventing and curing enteric disease of animal and paultory and its preparation method Download PDFInfo
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- CN1234384C CN1234384C CN 200410014150 CN200410014150A CN1234384C CN 1234384 C CN1234384 C CN 1234384C CN 200410014150 CN200410014150 CN 200410014150 CN 200410014150 A CN200410014150 A CN 200410014150A CN 1234384 C CN1234384 C CN 1234384C
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Abstract
The present invention relates to medicine for farm animals prepared from plant material, particularly to the field of a traditional Chinese preparation for preventing and treating enteric diseases of farm animals. Effective ingredients of the present invention comprise Chinese pulsatilla root, phellodendron amurense, Massa Medicata Fermentata, ash bark, charred sanguisorba root, heartleaf houttuynia herb, atractylodes rhizome, isatis root and common andrographis herd. The raw material is natural traditional Chinese medicine, so the present invention has the advantages of wide and sufficient resources, easy preparation, low cost, few side effects to farm animals, difficult generation of medicine resistance for pathogenic microorganisms after use, few harmful residues in animal bodies and no environmental pollution. In the present invention, modern traditional Chinese medicine is sued for preventing and treating enteric diseases of farm animals, which has the advantages of high efficiency, little toxicity and few residues. Therefore, food safety from animal origin and people's health are ensured.
Description
Technical field
What the present invention relates to is poultry medical supplies from vegetable material, particularly a kind of field of traditional Chinese of preventing and treating livestock and poultry intestinal canal diseases.
Background technology
As everyone knows, livestock and poultry intestinal canal diseases mainly is meant the animal and bird intestines infectious disease, as piglet pujos blancos, yellow scour of piglet, avian typhoid, swine enteritis, avian colibacillosis, Pullorum Disease etc.The infectious disease that these are common, multiple has seriously influenced animal growth and development, even causes large quantities of death, brings massive losses to herding production.At present, prevent and treat this type of disease both at home and abroad and also mainly adopt antibiotics.Long-term a large amount of use of antibiotic, particularly nonstandard abuse of antibiotics, can have side effects, the immunity degradation that causes making antibacterial develop immunity to drugs, cause the poultry body, cause the poultry autogenous infection, in livestock products and environment, cause toxic and side effects such as residual.The medicine that these are remaining, slowly accumulate in human body and other plant by livestock products and environment, finally come together in human body, cause human body to produce a large amount of Resistant strains with various approach, lose resistance, or body is produced toxic action because of accumulating in a large number to some disease.Developed countries such as European Union, Japan, the U.S. limit China's livestock products outlet on residue problem, and China's livestock products foreign exchange earning is obviously baffled.At these situations, the Ministry of Agriculture has forbidden producing, using former years at medicines such as the chloromycetin of preventing and treating consumption maximum on the livestock and poultry intestinal canal diseases, furazolidone this year.
Preventing and treating on the problem of livestock and poultry intestinal canal diseases, domestic and international highly competitive.External import veterinary drug is constantly in China's registration, though the import veterinary drug is novel relatively, prevention effect is better, it costs an arm and a leg; The import veterinary drug is chemical drugs in addition, pathogenic microorganism is developed immunity to drugs and forms drug residue.Therefore, development is efficient, low toxicity, the new veterinary drug of low-residual, becomes current very important and instant problem.
Summary of the invention
The Chinese medicine preparation that the purpose of this invention is to provide the control livestock and poultry intestinal canal diseases of a kind of efficient, low toxicity, low-residual.
Another object of the present invention is to provide the preparation method of the Chinese medicine preparation of above-mentioned control livestock and poultry intestinal canal diseases.
The active ingredient that the present invention prevents and treats the Chinese medicine preparation of livestock and poultry intestinal canal diseases is the Radix Pulsatillae, Cortex Phellodendri, six songs, Cortex Fraxini, charred Radix Sanguisorbae, Herba Houttuyniae, Rhizoma Atractylodis, Radix Isatidis, Herba Andrographis.
Above-mentioned various active ingredients preferably be: the composition by weight ratio of the Radix Pulsatillae, Cortex Phellodendri, six songs, Cortex Fraxini, charred Radix Sanguisorbae, Herba Houttuyniae, Rhizoma Atractylodis, Radix Isatidis, Herba Andrographis is: (2.5～3.5): (1.5～2.5): (1.5～2.5): (1.5～2.5): (1.5～2.5): (2.5～3.5): (0.5～1.5): (1.5～2.5): (2.5～3.5).
Above-mentioned various active ingredients preferably be: the composition by weight ratio of the Radix Pulsatillae, Cortex Phellodendri, six songs, Cortex Fraxini, charred Radix Sanguisorbae, Herba Houttuyniae, Rhizoma Atractylodis, Radix Isatidis, Herba Andrographis is: 3: 2: 2: 2: 2: 3: 1: 2: 3.
Its available following method preparation: after the roguing respectively of above-mentioned various medical materials, washing down, dry, grind, mix, make Chinese powder medicine.
The present invention compared with prior art has following advantage: Chinese medicine is the cultural treasure-house of China, has long history in several thousand, has accumulated rich experience in people and animals' disease preventing and treating.Raw material of Chinese medicine is from natural and wide material sources are sufficient, and easily preparation, cost are low, little to the poultry side effect, are difficult for causing pathogenic microorganism to produce drug resistance after the use, seldom form hazard residue in animal body, and be free from environmental pollution.The present invention prevents and treats livestock and poultry intestinal canal diseases with modern Chinese medicine, and efficient, low toxicity, low-residual have guaranteed the healthy of animal derived food safety and people, and Chinese medicine is good and cheap, also is that Western medicine can not be substituted.
Specific embodiment:
Embodiment one:
With the roguing respectively of various medical materials, wash down.
Take by weighing Radix Pulsatillae 75g, Cortex Phellodendri 50g, six bent 50g, Cortex Fraxini 50g, charred Radix Sanguisorbae 50g, Herba Houttuyniae 75g, Rhizoma Atractylodis 25g, Radix Isatidis 50g, Herba Andrographis 75g respectively, with water 150g, in container, decoct 90 minutes, leach medicinal liquid for the first time, add water to the submergence medicinal residues again, decoct 60 minutes for the second time, leach medicinal liquid for the second time, add water to the submergence medicinal residues again, decoct 45 minutes for the third time, leach medicinal liquid for the third time.
Merge three times medicinal liquid, be concentrated into 500ml, make medicinal liquid.
Get above-mentioned medicinal liquid 500ml, after the dilution of adding 500kg water, free choice feeding is prevented and treated.
Embodiment two:
Take by weighing Radix Pulsatillae 100g, Cortex Phellodendri 75g, six bent 75g, Cortex Fraxini 75g, charred Radix Sanguisorbae 50g, Herba Houttuyniae 100g, Rhizoma Atractylodis 30g, Radix Isatidis 75g, Herba Andrographis 100g respectively, with water 200g, in container, decoct 100 minutes, leach medicinal liquid for the first time, add water to the submergence medicinal residues again, decoct 60 minutes for the second time, leach medicinal liquid for the second time, add water to the submergence medicinal residues again, decoct 45 minutes for the third time, leach medicinal liquid for the third time.
Merge three times medicinal liquid, be concentrated into 650ml, make medicinal liquid.
Get above-mentioned medicinal liquid 500ml, after the dilution of adding 500kg water, free choice feeding is prevented and treated.
Embodiment three:
After each medical material oven dry with roguing, after washing down, pulverize standby.
Take by weighing Radix Pulsatillae 105g, Cortex Phellodendri 45g, six bent 45g, Cortex Fraxini 45g, charred Radix Sanguisorbae 45g, Herba Houttuyniae 105g, Rhizoma Atractylodis 20g, Radix Isatidis 70g, Herba Andrographis 105g after the pulverizing respectively, make bulk powder.
Clinical practice:
1, test drug: the present invention's powder and amoxicillin soluble powder (West China, Sichuan animal pharmaceutcal corporation, Ltd) are compared test.
2, experimental animal: natural occurrence is suffered from 1000～2000 of the sick chickens of escherichia coli, Salmonella, suffers from 400～600 of the pigs (cut open inspection and combine judgement with clinical) of piglet pujos blancos, dysentery.
3, test method: route of administration: spice.
The A group: amoxicillin soluble powder, chicken: every 100g this product spice 100kg, free choice feeding connects and fed 3～5 days.
The B group: powder of the present invention, chicken: every 250g this product spice 125kg, free choice feeding connects and fed 3～5 days.
4, curative effect of medication is judged (observing 3 days continuously after the drug withdrawal);
(1) cure: all at experimental session (comprising the observation period), its clinical symptoms after the medication: diarrhoea, row's green, yellow or white loose stool, be mixed with small amounts of blood sometimes: photophobia is shed tears, cough with asthma, nasal cavity or oral cavity stream viscosity liquid, mouth breathing, necking down are closed one's eyes, lassitude, and feather is fluffy and disorderly; Healing is normally all declared in recoveries such as peritonitis, airsacculitis, pericarditis, arthritis.
(2) effective: all at experimental session (comprising the observation period), its clinical symptoms is partly recovered normally all to declare effectively after the medication.
(3) invalid: all at experimental session (comprising the observation period), arbitrary clinical symptoms of its escherichia coli, Salmonella is not alleviated or is more serious, and it is invalid to be judged to be.
(4) death: all at experimental session (comprising the observation period), Salmonella and dead (cuing open inspection) is judged to be death appears because of ehec infection.
5, experimental result and record
Treatment chicken colibacillosis, Salmonella disease clinical efficacy
| Name of disease | Test group | Case | The course of treatment number (my god) | Recovery from illness number (only) | Good revolution (only) | Effective percentage | Cure rate |
| Colibacillosis | A | 450 | 3 | 324 | 40 | 80.8％ | 72.0％ |
| B | 600 | 3 | 528 | 36 | 94.0％ | 88.0％ | |
| Salmonellosis | A | 300 | 3 | 222 | 48 | 90.0％ | 74.0％ |
| B | 450 | 3 | 405 | 25 | 95.0％ | 90.0％ |
Treatment pig Hakuri, following dysentery clinical efficacy
| Name of disease | Test group | Case | The course of treatment number (my god) | Recovery from illness number (only) | Good revolution (only) | Effective percentage | Cure rate |
| Piglet pujos blancos | A | 80 | 3 | 54 | 13 | 83.8％ | 67.5％ |
| B | 120 | 3 | 102 | 8 | 91.7％ | 85.0％ | |
| The pig dysentery | A | 100 | 3 | 63 | 8 | 71.0％ | 63.0％ |
| B | 200 | 3 | 164 | 12 | 88.0％ | 82.0％ |
According to the clinical experiment result as can be seen, the present invention obviously is better than amoxicillin soluble powder to the effective percentage and the treatment rate of the treatment of escherichia coli, salmonellosis and piglet pujos blancos and pig dysentery.Therefore, the present invention is significant to the curative effect of escherichia coli, salmonellosis and piglet pujos blancos and pig dysentery.
Claims (3)
1, a kind of Chinese medicine preparation of preventing and treating livestock and poultry intestinal canal diseases, it is characterized in that: its active ingredient is the Radix Pulsatillae, Cortex Phellodendri, six songs, Cortex Fraxini, charred Radix Sanguisorbae, Herba Houttuyniae, Rhizoma Atractylodis, Radix Isatidis, Herba Andrographis, and the composition by weight ratio of each active ingredient Radix Pulsatillae, Cortex Phellodendri, six songs, Cortex Fraxini, charred Radix Sanguisorbae, Herba Houttuyniae, Rhizoma Atractylodis, Radix Isatidis, Herba Andrographis is: 2.5～3.5: 1.5～2.5: 1.5～2.5: 1.5～2.5: 1.5～2.5: 2.5～3.5: 0.5～1.5: 1.5～2.5: 2.5～3.5.
2, according to the Chinese medicine preparation of the described control livestock and poultry intestinal canal diseases of claim 1, it is characterized in that: the composition by weight ratio of its active ingredient Radix Pulsatillae, Cortex Phellodendri, six songs, Cortex Fraxini, charred Radix Sanguisorbae, Herba Houttuyniae, Rhizoma Atractylodis, Radix Isatidis, Herba Andrographis is: 3: 2: 2: 2: 2: 3: 1: 2: 3.
3, a kind of preparation method of preventing and treating the Chinese medicine preparation of livestock and poultry intestinal canal diseases, it is characterized in that: after the Radix Pulsatillae, Cortex Phellodendri, six songs, Cortex Fraxini, charred Radix Sanguisorbae, Herba Houttuyniae, Rhizoma Atractylodis, Radix Isatidis, Herba Andrographis roguing respectively, washing down, dry, grind, mix, make Chinese powder medicine; The composition by weight ratio of the Radix Pulsatillae, Cortex Phellodendri, six songs, Cortex Fraxini, charred Radix Sanguisorbae, Herba Houttuyniae, Rhizoma Atractylodis, Radix Isatidis, Herba Andrographis is: 2.5～3.5: 1.5～2.5: 1.5～2.5: 1.5～2.5: 1.5～2.5: 2.5～3.5: 0.5～1.5: 15～25: 2.5～3.5.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410014150 CN1234384C (en) | 2004-02-24 | 2004-02-24 | Chinese medicinal preparation for preventing and curing enteric disease of animal and paultory and its preparation method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410014150 CN1234384C (en) | 2004-02-24 | 2004-02-24 | Chinese medicinal preparation for preventing and curing enteric disease of animal and paultory and its preparation method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1559520A CN1559520A (en) | 2005-01-05 |
| CN1234384C true CN1234384C (en) | 2006-01-04 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 200410014150 Expired - Fee Related CN1234384C (en) | 2004-02-24 | 2004-02-24 | Chinese medicinal preparation for preventing and curing enteric disease of animal and paultory and its preparation method |
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Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102872396B (en) * | 2012-09-13 | 2014-05-07 | 广东海大集团股份有限公司 | Complex Chinese herbal medicine preparation for treating diarrhea of piglets and preparation method thereof |
| CN104083546A (en) * | 2014-06-20 | 2014-10-08 | 钟云仙 | Traditional Chinese medicine for treating animal enteritis and diarrhea |
| CN104083693A (en) * | 2014-06-20 | 2014-10-08 | 钟云仙 | Traditional Chinese medicine for treating animal enteritis |
| CN106310015A (en) * | 2016-09-18 | 2017-01-11 | 广西大学 | Traditional Chinese medicine preparation for treating poultry diarrhea |
| CN106310189A (en) * | 2016-09-18 | 2017-01-11 | 广西大学 | Traditional Chinese medicine preparation for treating poultry diarrhea and preparation method thereof |
| CN108936022A (en) * | 2018-08-07 | 2018-12-07 | 无为县旺盛饲料加工厂 | The special feed for preventing porkling dysentery |
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- 2004-02-24 CN CN 200410014150 patent/CN1234384C/en not_active Expired - Fee Related
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