CN1232695A - Health beverage capable of preventing and curing cold in the four seasons - Google Patents

Health beverage capable of preventing and curing cold in the four seasons Download PDF

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Publication number
CN1232695A
CN1232695A CN 99102906 CN99102906A CN1232695A CN 1232695 A CN1232695 A CN 1232695A CN 99102906 CN99102906 CN 99102906 CN 99102906 A CN99102906 A CN 99102906A CN 1232695 A CN1232695 A CN 1232695A
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radix
beverage
rhizoma
health beverage
chinese medicine
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李胤良
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Abstract

The health beverage is compounded with notopterygium, Radix Ledebouriellae, peppermint, gypsum, Forsythia suspensa and other 11 Chinese medicinal materials as well as honey, carrot juice, etc. It has the functions of regulating immunity, tonifying Qi, expelling superficial evils, and dispelling wind-evil and wetness-evil, and is used to cure cold in the four seasons, influenza, rheumatic arthritis, eczema and other disease. Pharmacological test shows that it has excellent antiphlogistic and antipyretic effect and non-specificity immunity strengthening function and thus can strengthen physique, prevent and cure disease.

Description

Control pestilent cold health beverage
The invention belongs to the category of beverage, specifically is a kind of health beverage of preventing and treating pestilent cold.
Along with growth in the living standard, people are also more and more higher to the prescription of beverage.Now the beverage types of all kinds on the market is various, samples differently, and kind is also in the increase of constantly updating.But a kind of health beverage that can prevent and treat pestilent cold is not appeared in the newspapers so far.
The objective of the invention is to develop a kind of new medicine beverage, control pestilent cold, influenza, rheumatic arthritis, eczema, eczema disease such as scratch where it itches.
One, medicine is formed:
Contain in the control pestilent cold health beverage: ten Six-element Chinese medicines such as Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Atractylodis, Radix Saposhnikoviae, Radix Bupleuri, Rhizoma Chuanxiong, Radix Platycodonis, Fructus Aurantii, Radix Peucedani, Poria, Radix Glycyrrhizae Preparata, Radix Codonopsis, Herba Menthae, Sucus Zingberis, Gypsum Fibrosum, Fructus Forsythiae, its percentage by weight separately is:
Rhizoma Et Radix Notopterygii 0.4167% Radix Angelicae Pubescentis 0.4167% Rhizoma Atractylodis 0.3125%
Radix Saposhnikoviae 0.3125% Radix Bupleuri 0.3125% Rhizoma Chuanxiong 0.3125%
Radix Platycodonis 0.3125% Fructus Aurantii 0.3125% Radix Peucedani 0.3125%
Poria 1.4584% Radix Glycyrrhizae Preparata 0.1561% Radix Codonopsis 0.4167%
Herba Menthae 0.2604% Sucus Zingberis 0.2083% Gypsum Fibrosum 0.4167%
Fructus Forsythiae 0.3125%
Liquid medicine in above-mentioned is carried the Chinese medicine extraction liquid of one times of amount of Chinese medicine weight, in extracting solution, add Mel, carrot-juice, Folium Perillae, essence, citric acid and water again and make beverage.Wherein Chinese medicine extraction liquid accounts for 6.25% of beverage weight.
The hydromining of synthetic beverage mineral spring distilled water.
Two, prescription analysis:
Rhizoma Et Radix Notopterygii has expelling wind and cold, the merit of removing damp and stopping pain, and normal and Radix Saposhnikoviae, Rhizoma Chuanxiong, Radix Angelicae Pubescentis are equal to usefulness; Radix Angelicae Pubescentis has diffusing wind dehumidification function equally; The effect that Radix Saposhnikoviae also has diffusing wind damp eliminating to induce sweat is applied to separate that to control affection of exogenous wind-cold damp effect in the anti-baidu powder of table name prescription fine with Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis compatibility, with Herba Menthae, Radix Platycodonis, Fructus Forsythiae with controlling anemopyretic cold again; But the Sucus Zingberis expelling cold and relieving exterior syndrome, the preventing or arresting vomiting effect is also fine; Rhizoma Atractylodis can expelling wind and removing dampness, and with Radix Saposhnikoviae, compatibilities such as Rhizoma Et Radix Notopterygii can be used for the joint limbs pain that rheumatism or cold-damp cause; Rhizoma Chuanxiong energy wind-expelling pain-stopping can be controlled wind and cold, wind heat, headache due to pathogenic wind-dampness respectively with Radix Saposhnikoviae, Gypsum Fibrosum, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis compatibility; Radix Bupleuri can induce sweat and bring down a fever, and is good at evacuating the heresy of few positive half exterior and half interior; Herba Menthae can be evacuated and induce sweat, and clearing throat can be used for affection due to external wind and heat, also can with Radix Saposhnikoviae, compatibilities such as Rhizoma Et Radix Notopterygii are used for affection of exogenous wind-cold, but the Fructus Forsythiae clearing away heat and expelling pathogen in the exterior share the treatment anemopyretic cold with pungent and cold medicine for relieving the exterior syndrome such as Radix Bupleuri, Herba Menthaes; The Radix Peucedani wind heat clearing away of loosing, lowering the adverse-rising QI and dispelling phlegm, with Herba Menthae, compatibilities such as Radix Platycodonis can be used for the wind heat diseases caused by exogenous pathogenic factor, cough with copious phlegm; Radix Platycodonis has the merit of eliminating phlegm and stopping cough, can be used for the cough due to pathogenic wind-heat, is used for the pharyngalgia hoarseness with compatibilities such as Radix Glycyrrhizae, Herba Menthaes, can be used for stagnation of QI causing phlegm retention with the Fructus Aurantii compatibility, and is uncomfortable in chest not smooth; Radix Glycyrrhizae energy nourishing the lung to arrest cough is equal to relaxing benefit power with tonic such as Radix Codonopsis, makes effect slowly and lastingly; The Fructus Aurantii painful abdominal mass that disappears of can reducing phlegm; Poria can eliminating dampness and diuresis, can be used for water damp-phlegm drink, can also the Piao Yi taste, and invigorating the spleen and benefiting QI medicine compatibilities such as normal and Radix Codonopsis; Radix Codonopsis can invigorating the spleen and replenishing QI, but replenishing and restoring lung-QI also is used for weakness of the spleen and stomach, and breathing hard breathes with cough waits disease, and it is thirsty also to can be used for breathing hard, with diaphoretic medicine with controlling body void diseases caused by exogenous pathogenic factor; But the Gypsum Fibrosum clearing away lung-heat can be controlled the strongly fragrant lung of pathogenic heat with depressed lung-energy dispersing medicine compatibility such as Radix Glycyrrhizae, dyspnea with rapid and short breath cough, thirst with desire to drink.Full side share, and both can evacuate to induce sweat and cure cold, and immunity-regulating strengthens resistance against diseases again, can also eliminate the phlegm to improve symptom by relieving cough and asthma, takes into account in many ways, and pestilent cold is all had treatment and health-care effect.
Three, modern relevant pharmacology, the clinical research report:
Rhizoma Et Radix Notopterygii volatile oil can significantly reduce the pyrogenicity rat temperature, can also obviously resist mice acetic acid twisting reaction, has significantly analgesicly, and analgesic effect (1) also has antiinflammatory, antiallergic and antibacterial action (2); It is pain caused that Radix Angelicae Pubescentis can obviously resist hot plate, also can be calm and Chinese People's Anti-Japanese Military and Political College's Mus formaldehyde due to inflammation, tangible antibacterial action (3) is arranged simultaneously, treating chronic bronchitis clinically has certain curative effect (4); The pyrogenicity reaction (5) of anti-wind energy antagonism triple vaccine, anti-Ovum Gallus domesticus album inflammation (6), can also strengthen carbon clearance exponential sum phagocytosis of macrophages, and have antibiotic, antiviral activity (7), clinical have the treatment the arthralgic report in chronic back (8), Sucus Zingberis has the town to tell effect (9), the capillary permeability that oil of Rhizoma Zingiberis Recens can suppress due to histamine and the acetic acid increases, suppress multiple inflammation (10), Rhizoma Zingiberis Recens extract also has antibacterial activity (11) widely, clinical important city vomiting (12), carsick (13) and the various acute inflammation (14) controlled; Rhizoma Atractylodis have the activity of kill bacteria and virus, and oxygen lack resistant function (15) is arranged, and can prevent chickenpox clinically, scarlet fever, parotitis, (16) such as flu and tracheitiies; Rhizoma Chuanxiong causes the isolated tracheal smooth muscle spasm of breathing heavily due to the medium to some certain inhibitory action, can prevent, protection experimental lung edema, the experimental lung edema due to disorder of QI also there is certain effect (17), can also suppress acetic acid twisting reaction (18), the clinical migraine (19) of preventing and treating, treatment stage of attack bronchial asthma (20), headache, disease (21) such as dizzy; Radix Bupleuri has tangible antipyretic effect to the fever model that multiple vaccine and pyrogenicity medium cause, multiple pain model there is obvious analgesic activity, also have many-sided antiinflammatory and immunological enhancement in addition, antitussive effect also apparent in view (22), can be used for bring down a fever (23) clinically, cough (24), mumps (25) etc.; Herba Menthae has antibiotic widely, antiviral activity, also has certain expectorant effect (26); Fructus Forsythiae has very strong antibiotic, antiviral activity (27), can reduce the body temperature (28) of fever in rabbit due to immersion of hay bacterium and the Typhoid Vaccine, also has tangible antiinflammatory (29) and town's effect of telling (30); Radix Peucedani eliminates the phlegm (31), antiinflammatory (32), anti-allergic effects (33); Radix Platycodonis has tangible phlegm-dispelling functions (34) and antitussive effect (35) to multiple animal, also has antiinflammatory action widely, also can suppress leukoplania, strengthen the sterilizing power of neutrophilic leukocyte, improve shallow lake bacterium enzymatic activity, strengthen the phagocytic function of macrophage, calmness, analgesia, refrigeration function (36) are still arranged in addition, be used for various respiratory road and bottleneck throat inflammation such as pneumonia clinically, chronic bronchitis, treating child asthma pneumonia, acute tonsillitis, acute pharyngitis etc. (37); Radix Glycyrrhizae has many-sided antiinflammatory action and immunological enhancement, also has the activity of anti-multiple virus and antibacterial, and cough-relieving, the effect of eliminating the phlegm, relievining asthma be (38) also clearly, clinical treat (40) such as chronic pharyngitis (39) and pulmonary tuberculosis; Poria has the effect of comprehensive raise immunity, also has certain antibacterial action (41); Radix Codonopsis can many-sidedly improve anti-stress ability and raise immunity, also has certain analgesia, antiinflammatory and antibacterial action (42); Gypsum Fibrosum and compound recipe thereof have tangible antipyretic effect to multiple fever model, can also improve the phagocytic function (43) of macrophage, clinical hyperpyrexia (44) influenza (45) that is used for the treatment of, and toothache curative effects such as (46) is fine.
Four, control pestilent cold health beverage is as follows through Shanxi Institute of Traditional Chinese Medicine's Chinese medicinal formulae institute experimentation:
The pharmacological experiment study of control pestilent cold health beverage
Shanxi Institute of Traditional Chinese Medicine's Chinese medicinal formulae institute
Control pestilent cold health beverage has immunomodulating, supplementing QI for expelling the pathogenic factors from the body surface, and the eliminating evil function of wind of loosing mainly acts in order to verify it, and the spy has carried out following experimentation to it.
A, experiment material
1, sample use in test: be that the Shanxi offspring is led to the control pestilent cold health beverage that new and high technology comprehensive exploitation company limited Li Yin very provides, the concentrated solution of getting its stock solution and 1: 2 respectively is for experiment.
2, animal: rabbit and 20 ± 2g Kunming mouse are planted by 1.6 ± 0.2kg New Zealand, are male and female half and half, are provided by the court laboratory animal room.
Five, method and result
1, to the influence of reticuloendothelial system phagocytic function; 30 of mices, be divided into three groups at random, 10 every group, experimental group is used stock solution respectively and is concentrated at 1: 2 with the dosage of 40ml/kg and irritates stomach, once a day, continuous irrigation stomach three days, matched group is given consubstantiality hydrops, 15min after last is irritated stomach, animal tail vein injection 20% india ink 0.1ml/10g, injection back 2 and 20min eye socket respectively get in the 0.1%NaHCO3 solution that blood 20ul is dissolved in 2ml, measure its trap value at 365nm place, calculating phagocytic index K.The results are shown in Table 1, experimental group K value shows that all apparently higher than matched group this product can the enhancing non-specific immunity function.
Table 1: to the influence of reticuloendothelial system phagocytic function (α ± SD)
Group Dosage (ml/kg * d) Phagocytic index K The P value
Matched group (10) 0×3 ?0.039±0.007
Stock solution (10) 40×3 ?0.046±0.006 ????<0.05
1: 2 concentrated solution (10) 40×3 ?0.050±0.008 ????<0.01
2, antiinflammatory action: classification is the same with the filling stomach, and the right back foot pad of the every Mus of 30min SC.1% Ovum Gallus domesticus album solution 0.05ml causes inflammation after last is irritated stomach, and 5h measures the thickness of two metapedes as the swelling degree behind the Yu Zhiyan with micrometer callipers.The results are shown in Table 2, the right back sufficient swelling degree of experimental group animal all is starkly lower than matched group, shows that this product has antiinflammatory action.
Table 2: mice Ovum Gallus domesticus album is caused scorching influence (α ± SD)
Group Dosage (ml/kg * d) Swelling degree (mm) The P value
Matched group (10) 0×3 ?0.66±0.21
Stock solution (10) 40×3 ?0.45±0.20 ????<0.05
1: 2 concentrated solution (10) 40×3 ?0.38±0.25 ????<0.05
3, refrigeration function: 15 of rabbit, be divided into three groups at random, every group 5, experiment before measurement anus temperature for several times, select the more constant rabbit of body temperature as experimental subject, experimental group uses stock solution and 1: 2 concentrated solution to irritate stomach with the dosage of 15ml/kg respectively then, once a day, irritated stomach altogether three days, matched group is given consubstantiality hydrops, last is surveyed the anus temperature twice before irritating stomach again, and with its meansigma methods as normal body temperature, irritate stomach then, every rabbit of 30min is injected typhoid fever with the dosage of 1.2ml/kg by ear vein thereafter, paratyphoid fever the first and second three bacterium mattress pyrogenicity are after pyrogenicity 1,3,5h surveys the anus temperature respectively one time.The results are shown in Table 3,1h after the pyrogenicity, experimental group body temperature just continues to be lower than matched group, shows this product antipyretic effect clearly.
Table 3: to the influence of fever in rabbits (α ± SD)
Group Dosage (ml/kg * d) Fervescence value after the pyrogenicity (℃) 1h 3h 5h
Matched group (5) 0×3 ?1.7±0.3 1.8±0.4 2.0±0.3
Stock solution (5) 15×3 ?1.3±0.2* 1.2±0.3* 1.0±0.7*
1: 2 concentrated solution (5) 15×3 ?1.0±0.6* 1.0±0.6* 0.8±0.6*
*P<0.05????**P<0.01
Discuss
Flu generally all has inflammation and heating paresthesia, and hypoimmunity is easier catches a cold, from above experimental result as seen, this product has good antiinflammatory and antipyretic effect, this is very beneficial to alleviating patient's symptom, simultaneously this product can also the enhancing non-specific immunity function, and for health invigorating, prevent disease also is very useful.
Six, control pestilent cold health beverage has immunomodulating, supplementing QI for expelling the pathogenic factors from the body surface, and the eliminating evil function of wind of loosing can be used for pestilent cold, influenza, rheumatic arthritis, eczema, eczema disease such as scratch where it itches.And this beverage is middle Types of Medicine beverage, do not add any antiseptic, and safe for drinking has no side effect.
Seven, below in conjunction with embodiment control pestilent cold health beverage is elaborated:
Rhizoma Et Radix Notopterygii 1g Radix Angelicae Pubescentis 1g Rhizoma Atractylodis 0.75g
Radix Saposhnikoviae 0.75g Radix Bupleuri 0.75g Rhizoma Chuanxiong 0.75g
Radix Platycodonis 0.75g Fructus Aurantii 0.75g Radix Peucedani 0.75g
Poria 3.5g Radix Glycyrrhizae Preparata 0.375 Radix Codonopsis 1g
Herba Menthae 0.625g Sucus Zingberis 0.5g Gypsum Fibrosum 1g
Fructus Forsythiae 0.75g
Last prescription amounts to Chinese medicine ten Six-elements, meter weight 15 grams.Liquid medicine in above-mentioned is carried the Chinese medicine extraction liquid of one times of amount of Chinese medicine weight.
Get Chinese medicine extraction liquid 15g, carrot-juice 60g, adding Mel, Folium Perillae, essence, citric acid, mineral spring distilled water are made carbonated beverage, are contained in the easy-to-draw beverage can every jar of 240g.
List of references
(1) Xu Huibo etc., careless Chinese medicine, 1991; 22 (1): 28
(2) Jin Shufen etc.Chinese patent medicine research, 1981; (12): 41
(3) cloudy strong chief editor.Chinese medicine modern study and clinical practice (1), Beijing: Xueyuan Press, 1993; 507-508
(4) Wuhan No.4 Hospital, Wuhan new medicine, 1971; (3) 24
(5) Golden Temple has, Chinese medicine information, 1985; (4): 40
(6) Song Zhenyu etc., Acta Pharmaceutica Sinica, 1963; 10 (12): 708
(7) with (3), 329 pages
(8) Lei Lun etc., the Shaanxi traditional Chinese medical science, 1988; 9 (10): 461
(9) perfume (or spice) on the mountain.Folia Pharmacologica Japonica (day), 1953; 49 (3): 72
(10) Zhang Zhuxin etc., Chinese herbal medicine, 1989; 20 (12): 17
(11) with (3), 237 pages
(12) Sunbo qin.The new traditional Chinese medical science, 1986; (12): 24
(13) Pan Shaofeng.Popular Medicine, 1980; (9): 7
(14) defend Tian Hui etc.Combination of Chinese and Western medicine magazine, 1990; 10 (8): 478
(15) with (3), 346 pages
(16) Tung Wah hospital etc., medical condition exchanges, and 1974; (2): back cover
(17) with (3), 112 pages
(18) Wan Fuchang etc.Pharmacology and Clinics of Chinese Materia Medica, 1990; 6 (5): 34
(19) king's sweet-smelling grass etc., Yunnan Journal of Traditional Chinese Medicine, 1980; (4): 11
(20) Shao Changrong etc., journal of shanghai Chinese medicine, 1990; (8): 18
(21) peach blossom face of a beauty.Herbal pharmacology and application, Beijing: People's Health Publisher, 1958; 117
(22) with (3), 541-542
(23) Guizhou medical treatment news, 1981; (1): 33
(24) wide back hospital, 1987; (4): 41
(25) Xu Lajin, the new traditional Chinese medical science, 1986; 18 (6): 14
(26) with (3), the 683-684 page or leaf
(27) with (3), 357 pages
(28) with (27)
(29) Zhu checks and can wait, combination of Chinese and Western medicine compilation of data acute abdomen, second collection, 1979; 64
(30) relief osmanthus etc., Tianjin medical magazine, 1960; 2 (2): 131
(31) white horse with a black mane and life etc., the pharmacology of Chinese medicinal formulae and clinical progress, publishing house of South China Science ﹠ Engineering University, 1991; 139
(32) interior Tian Xinghong.Foreign medical science Chinese medicine fascicle, 1986; 8 (4): 35
(33) Kong Lingyi etc., foreign medical science plant amedica fascicle, 1991; 6 (6): 243
(34) Zhao Gengxian etc., Chinese crude drug, 1989; 12 (1): 38
(35) Lee Yin Fang, modern Japan medical science, 1983; 4 (3): 42
(36) with (3), the 2nd, the 288-289 page or leaf
(37) with (3), the 2nd, the 290-291 page or leaf
(38) with (3), the 200-202 page or leaf
(39) Song Yuanzhong, Yunnan University of Traditional Chinese Medicine's journal, 1983; (1): 20
(40) Zhao Shulin etc.Jiangxi medicine, 1965; (1): 562
(41) with (3), the 490-491 page or leaf
(42) with (3), 550,553 pages
(43) with (3), the 213-214 page or leaf
(44) model national literature.Journal of Traditional Chinese Medicine, 1989; 30 (10): 2
(45) Yang Zuoshi, Chinese countryside medical science, 1982; (6): 17
(46) Jia Yuanbo.The Shanxi traditional Chinese medical science, 1986; 2 (3): 29

Claims (4)

1, a kind of control pestilent cold health beverage, include Mel, carrot-juice, Folium Perillae, essence, citric acid, Chinese medicine extraction liquid and water in the beverage, it is characterized in that containing in the Chinese medicine extraction liquid: ten Six-element Chinese medicines such as Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Rhizoma Atractylodis, Radix Saposhnikoviae, Radix Bupleuri, Rhizoma Chuanxiong, Radix Platycodonis, Fructus Aurantii, Radix Peucedani, Poria, Radix Glycyrrhizae Preparata, Radix Codonopsis, Herba Menthae, Sucus Zingberis, Gypsum Fibrosum, Fructus Forsythiae, its percentage by weight separately is:
Rhizoma Et Radix Notopterygii 0.4167% Radix Angelicae Pubescentis 0.4167% Rhizoma Atractylodis 0.3125%
Radix Saposhnikoviae 0.3125% Radix Bupleuri 0.3125% Rhizoma Chuanxiong 0.3125%
Straw obstruct 0.3125% Fructus Aurantii, 0.3125% Radix Peucedani 03125%
Poria 1.4584% Radix Glycyrrhizae Preparata 0.1561% Radix Codonopsis 0.4167%
Herba Menthae 0.2604% Sucus Zingberis 0.2083% Gypsum Fibrosum 0.4167%
Fructus Forsythiae 0.3125%
2, control pestilent cold health beverage according to claim 1 is characterized in that above-mentioned Chinese medicine extraction liquid accounts for 6.25% of beverage weight.
3, control pestilent cold health beverage according to claim 1 is characterized in that being added with in the beverage carrot-juice.
4, control pestilent cold health beverage according to claim 1 is characterized in that the hydromining of synthetic beverage is adopted distilled water with the ore deposit.
CN 99102906 1999-03-09 1999-03-09 Health beverage capable of preventing and curing cold in the four seasons Pending CN1232695A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1305521C (en) * 2005-10-26 2007-03-21 牟培新 Cold treating medicine
CN101755975A (en) * 2010-01-25 2010-06-30 中山市新运来医药科技开发有限公司大涌分公司 Chinese herbal medicine sugar and tea drink preparation for preventing and treating cold
WO2012089175A2 (en) * 2010-12-31 2012-07-05 Ke Shuquan Traditional chinese medicinal tea made by microbial fermentation
CN103251821A (en) * 2013-06-03 2013-08-21 肖变化 Medicine for treating wind-heat headache and migraine headache and preparation method of medicine
CN103493887A (en) * 2013-08-27 2014-01-08 利辛县梓博农副产品购销有限公司 Peanut-containing sea-tangle juice beverage and preparation method
CN104997821A (en) * 2015-07-07 2015-10-28 扬子江药业集团北京海燕药业有限公司 Use of Radix Peucedani extract in immune function improvement

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1305521C (en) * 2005-10-26 2007-03-21 牟培新 Cold treating medicine
CN101755975A (en) * 2010-01-25 2010-06-30 中山市新运来医药科技开发有限公司大涌分公司 Chinese herbal medicine sugar and tea drink preparation for preventing and treating cold
WO2012089175A2 (en) * 2010-12-31 2012-07-05 Ke Shuquan Traditional chinese medicinal tea made by microbial fermentation
WO2012089175A3 (en) * 2010-12-31 2012-09-20 永富亚洲集团有限公司 Traditional chinese medicinal tea made by microbial fermentation method
CN103251821A (en) * 2013-06-03 2013-08-21 肖变化 Medicine for treating wind-heat headache and migraine headache and preparation method of medicine
CN103493887A (en) * 2013-08-27 2014-01-08 利辛县梓博农副产品购销有限公司 Peanut-containing sea-tangle juice beverage and preparation method
CN104997821A (en) * 2015-07-07 2015-10-28 扬子江药业集团北京海燕药业有限公司 Use of Radix Peucedani extract in immune function improvement

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