CN1219764C - W-carboxyaryl substituted diphenyl ureas as RAF kinase inhibitors - Google Patents

W-carboxyaryl substituted diphenyl ureas as RAF kinase inhibitors Download PDF

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Publication number
CN1219764C
CN1219764C CNB008026858A CN00802685A CN1219764C CN 1219764 C CN1219764 C CN 1219764C CN B008026858 A CNB008026858 A CN B008026858A CN 00802685 A CN00802685 A CN 00802685A CN 1219764 C CN1219764 C CN 1219764C
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CN
China
Prior art keywords
phenyl
acid
trifluoromethyl
urea
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CNB008026858A
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Chinese (zh)
Other versions
CN1341098A (en
Inventor
B·里德
J·迪马
U·基海尔
T·B·洛因格
W·J·斯科特
R·A·史密斯
J·E·伍德
M-K·莫纳汉
R·纳特罗
J·雷尼克
R·N·西布利
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Bayer Pharmaceuticals Corp
Original Assignee
Bayer Corp
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Filing date
Publication date
Family has litigation
Priority to US11587799P priority Critical
Priority to US60/115,877 priority
Priority to US25726699A priority
Priority to US09/257,266 priority
Priority to US42522899A priority
Priority to US09/425,228 priority
Application filed by Bayer Corp filed Critical Bayer Corp
Publication of CN1341098A publication Critical patent/CN1341098A/en
Application granted granted Critical
Publication of CN1219764C publication Critical patent/CN1219764C/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27381740&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN1219764(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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