AU9802198A - Antiinflammatory thiadiazolyl ureas which act as lfa-1 and mac-1 inhibitors - Google Patents

Antiinflammatory thiadiazolyl ureas which act as lfa-1 and mac-1 inhibitors

Info

Publication number
AU9802198A
AU9802198A AU98021/98A AU9802198A AU9802198A AU 9802198 A AU9802198 A AU 9802198A AU 98021/98 A AU98021/98 A AU 98021/98A AU 9802198 A AU9802198 A AU 9802198A AU 9802198 A AU9802198 A AU 9802198A
Authority
AU
Australia
Prior art keywords
lfa
antiinflammatory
mac
inhibitors
act
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU98021/98A
Inventor
Ronald B. Gammill
Mark Allen Mitchell
Richard Allen Nugent
Susan Vander Velde
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Pharmacia and Upjohn Co
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn Co, Upjohn Co filed Critical Pharmacia and Upjohn Co
Publication of AU9802198A publication Critical patent/AU9802198A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
AU98021/98A 1997-10-21 1998-10-20 Antiinflammatory thiadiazolyl ureas which act as lfa-1 and mac-1 inhibitors Abandoned AU9802198A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6276897P 1997-10-21 1997-10-21
US60062768 1997-10-21
PCT/US1998/021630 WO1999020617A1 (en) 1997-10-21 1998-10-20 Antiinflammatory thiadiazolyl ureas which act as lfa-1 and mac-1 inhibitors

Publications (1)

Publication Number Publication Date
AU9802198A true AU9802198A (en) 1999-05-10

Family

ID=22044673

Family Applications (1)

Application Number Title Priority Date Filing Date
AU98021/98A Abandoned AU9802198A (en) 1997-10-21 1998-10-20 Antiinflammatory thiadiazolyl ureas which act as lfa-1 and mac-1 inhibitors

Country Status (2)

Country Link
AU (1) AU9802198A (en)
WO (1) WO1999020617A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6110922A (en) 1998-12-29 2000-08-29 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
US6878700B1 (en) 1998-12-29 2005-04-12 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
WO2000042012A1 (en) * 1999-01-13 2000-07-20 Bayer Corporation φ-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
EP2298311B1 (en) 1999-01-13 2012-05-09 Bayer HealthCare LLC w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
CA2549558C (en) * 1999-01-13 2010-08-31 Bayer Corporation Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
DE60026822T2 (en) * 1999-01-13 2006-08-24 Bayer Pharmaceuticals Corp., West Haven -G (V) -CARBOXYARYL SUBSTITUTED DIPHENYL UREAIDS AS RAF KINASE INHIBITORS
DE10005150A1 (en) 2000-02-07 2001-08-09 Merck Patent Gmbh Process for the preparation of 5-arylnicotinaldehydes
US6521619B2 (en) 2000-06-29 2003-02-18 Icos Corporation Aryl phenylcyclopropyl sulfide derivatives and their use as cell adhesion inhibiting anti-inflammatory and immune suppressive agents
NZ523445A (en) 2000-06-29 2004-10-29 Abbott Lab Aryl phenylheterocyclyl sulfide derivatives and their use as cell adhesion-inhibiting anti-inflammatory and immune-suppressive agents
ES2200617B1 (en) * 2001-01-19 2005-05-01 Almirall Prodesfarma, S.A. DERIVATIVES OF UREA AS ANTAGONISTS OF INTEGRINAS ALPHA 4.
WO2003068746A1 (en) 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Aryl ureas as kinase inhibitors
MXPA04007832A (en) 2002-02-11 2005-09-08 Bayer Pharmaceuticals Corp Aryl ureas with angiogenesis inhibiting activity.
US6974815B2 (en) 2002-10-11 2005-12-13 Bristol-Myers Squibb Company Hexahydro-benzimidazolone compounds useful as anti-inflammatory agents
CA2526617C (en) 2003-05-20 2015-04-28 Bayer Pharmaceuticals Corporation Diaryl ureas with kinase inhibiting activity
UA84156C2 (en) 2003-07-23 2008-09-25 Байер Фармасьютикалс Корпорейшн Fluoro substituted omega-carboxyaryl diphenyl urea for the treatment and prevention of diseases and conditions
US7199125B2 (en) 2003-10-02 2007-04-03 Bristol-Myers Squibb Company Spiro-cyclic compounds useful as anti-inflammatory agents
DE102004009933A1 (en) * 2004-02-26 2005-09-15 Merck Patent Gmbh Use of 1,3,4-thiadiazole derivatives to prepare medicaments for treating diseases in which the inhibition, regulation or modulation of kinase signal transduction plays a role
US7375237B2 (en) 2004-08-18 2008-05-20 Bristol-Myers Squibb Company Pyrrolizine compounds useful as anti-inflammatory agents
TW200616634A (en) 2004-10-01 2006-06-01 Bristol Myers Squibb Co Crystalline forms and process for preparing spiro-hydantoin compounds
US7186727B2 (en) 2004-12-14 2007-03-06 Bristol-Myers Squibb Company Pyridyl-substituted spiro-hydantoin compounds and use thereof
WO2010054393A1 (en) * 2008-11-10 2010-05-14 Mount Sinai School Of Medicine Of New York University Methods of inhibiting inflammation-associated tissue damage by inhibiting neutrophil activity
MX2012002596A (en) 2009-09-03 2012-07-03 Allergan Inc Compounds as tyrosine kinase modulators.
US9340555B2 (en) 2009-09-03 2016-05-17 Allergan, Inc. Compounds as tyrosine kinase modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3990879A (en) * 1974-12-26 1976-11-09 Eli Lilly And Company Method of controlling aquatic weeds
US4576629A (en) * 1984-03-15 1986-03-18 Union Carbide Corporation Herbicidal thiadiazole ureas
NZ231534A (en) * 1988-11-29 1992-02-25 Warner Lambert Co 3,5-di-t-butyl-4-hydroxyphenyl-triazoles, oxadiazoles and thiadiazoles; anti-inflammatory compositions
US5102897A (en) * 1990-03-27 1992-04-07 Warner-Lambert Company 3,5-ditertiarybutyl-4-hydroxyphenyl, 1,3,4-thiadiazoles and oxadiazoles linked by carbon, oxygen, and sulfur residues
WO1992008464A1 (en) * 1990-11-15 1992-05-29 Tanabe Seiyaku Co. Ltd. Substituted urea and related cell adhesion modulation compounds

Also Published As

Publication number Publication date
WO1999020617A1 (en) 1999-04-29

Similar Documents

Publication Publication Date Title
AU9802198A (en) Antiinflammatory thiadiazolyl ureas which act as lfa-1 and mac-1 inhibitors
AU7356198A (en) Smartcard and method for its manufacture
AU4605296A (en) Tab fastener
AU6038796A (en) Fastener and fastening method, particularly for fastening su tures to bone
AU2021097A (en) Fastening nail
AU9391098A (en) Fastening system
AU3780797A (en) Self-adhesive labels and manufacture thereof
AU8591398A (en) Workflow systems and methods
AU7470398A (en) Titanium crystal and titanium
AU6026098A (en) Sulfur removal process
AU5991699A (en) Quinolizinones as integrin inhibitors
AU8279998A (en) Retained fastener
AU1686600A (en) Chlorophyll-rich and salt-resistant chlorella
AU4598296A (en) Fastening tab
AU1998399A (en) Computer instruction which generates multiple data-type results
AU6455099A (en) Fastener
AU6422798A (en) Stabilized urease inhibitor
AU8385898A (en) Paint removal composition and system
AU4963896A (en) Stud removal and fastening tool specification
AU3717897A (en) Protease and related nucleic acid compounds
AU5622498A (en) V-nail fastener
AUPO935597A0 (en) Improved fastening method
AU5296698A (en) Process of coal liquefaction
AU6640498A (en) Package and method of making the same
AU6558298A (en) Clock gene and gene product

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase