CN121843933A - 单一的轴手性化合物的选择性制造法 - Google Patents
单一的轴手性化合物的选择性制造法Info
- Publication number
- CN121843933A CN121843933A CN202480055263.4A CN202480055263A CN121843933A CN 121843933 A CN121843933 A CN 121843933A CN 202480055263 A CN202480055263 A CN 202480055263A CN 121843933 A CN121843933 A CN 121843933A
- Authority
- CN
- China
- Prior art keywords
- compound
- formula
- group
- salt
- following
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JPPCT/JP2023/032816 | 2023-09-08 | ||
| PCT/JP2023/032816 WO2025052649A1 (ja) | 2023-09-08 | 2023-09-08 | 単一の軸不斉化合物の選択的製造法 |
| PCT/JP2024/031959 WO2025053242A1 (ja) | 2023-09-08 | 2024-09-06 | 単一の軸不斉化合物の選択的製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN121843933A true CN121843933A (zh) | 2026-04-10 |
Family
ID=94923286
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202480055263.4A Pending CN121843933A (zh) | 2023-09-08 | 2024-09-06 | 单一的轴手性化合物的选择性制造法 |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JP7700399B1 (https=) |
| CN (1) | CN121843933A (https=) |
| AU (1) | AU2024337896A1 (https=) |
| CO (1) | CO2026004110A2 (https=) |
| MX (1) | MX2026002723A (https=) |
| TW (1) | TW202527939A (https=) |
| WO (2) | WO2025052649A1 (https=) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JOP20190186A1 (ar) * | 2017-02-02 | 2019-08-01 | Astellas Pharma Inc | مركب كينازولين |
| WO2022173032A1 (ja) * | 2021-02-15 | 2022-08-18 | アステラス製薬株式会社 | G12d変異krasタンパクの分解を誘導するためのキナゾリン化合物 |
| EP4293025B1 (en) * | 2021-02-15 | 2025-10-29 | Astellas Pharma Inc. | 4-aminoquinazoline compound |
| TW202346270A (zh) * | 2022-03-11 | 2023-12-01 | 日商安斯泰來製藥股份有限公司 | 用於誘發g12d突變kras蛋白分解之雜環化合物 |
| US20250145631A1 (en) * | 2022-07-21 | 2025-05-08 | Astellas Pharma Inc. | Heterocyclic compound acting on g12d mutant kras protein |
| TW202412789A (zh) * | 2022-08-05 | 2024-04-01 | 日商安斯泰來製藥股份有限公司 | 用於誘導突變kras蛋白分解之雜環化合物 |
| EP4570794A1 (en) * | 2022-08-09 | 2025-06-18 | Astellas Pharma, Inc. | Heterocyclic compound for inhibiting and/or inducing degradation of kras protein |
| EP4570795A1 (en) * | 2022-08-09 | 2025-06-18 | Astellas Pharma, Inc. | Heterocyclic compound for inducing degradation of g12v mutant kras protein |
-
2023
- 2023-09-08 WO PCT/JP2023/032816 patent/WO2025052649A1/ja active Pending
-
2024
- 2024-09-06 AU AU2024337896A patent/AU2024337896A1/en active Pending
- 2024-09-06 TW TW113133938A patent/TW202527939A/zh unknown
- 2024-09-06 CN CN202480055263.4A patent/CN121843933A/zh active Pending
- 2024-09-06 JP JP2025523047A patent/JP7700399B1/ja active Active
- 2024-09-06 WO PCT/JP2024/031959 patent/WO2025053242A1/ja active Pending
-
2026
- 2026-03-06 MX MX2026002723A patent/MX2026002723A/es unknown
- 2026-03-30 CO CONC2026/0004110A patent/CO2026004110A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2026002723A (es) | 2026-04-01 |
| TW202527939A (zh) | 2025-07-16 |
| JP7700399B1 (ja) | 2025-06-30 |
| WO2025052649A1 (ja) | 2025-03-13 |
| WO2025053242A1 (ja) | 2025-03-13 |
| CO2026004110A2 (es) | 2026-04-16 |
| AU2024337896A1 (en) | 2026-03-19 |
| JPWO2025053242A1 (https=) | 2025-03-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2017250302B2 (en) | Inhibitors of activin receptor-like kinase | |
| CN103429243B (zh) | Cdk抑制剂 | |
| EP3956320B1 (en) | Dihydroorotate dehydrogenase inhibitors | |
| CN108699063A (zh) | 一种芦可替尼的合成工艺 | |
| US12077528B2 (en) | Preparation method for deuterated macrocyclic compound | |
| JPWO2014042176A1 (ja) | 縮合複素環誘導体の製造方法およびその製造中間体 | |
| CN115151529B (zh) | 用于制备乌帕替尼的方法和中间体 | |
| CN120418252A (zh) | Malt1抑制剂 | |
| JP2024526762A (ja) | Jak阻害剤を調製するためのプロセス及び中間体 | |
| EP2168952A1 (en) | Morpholine derivative | |
| JP2017516822A (ja) | デュオカルマイシンのプロドラッグを製造するための改良された方法 | |
| EP1602646A1 (en) | Processes for producing cyclic benzamidine derivative | |
| EP4472982A1 (en) | Processes for the preparation of selective estrogen receptor degraders | |
| CN121843933A (zh) | 单一的轴手性化合物的选择性制造法 | |
| CN107531680B (zh) | 一种毒素及其中间体的制备方法 | |
| JP2017081832A (ja) | トリアジンジオン化合物 | |
| CN117377660A (zh) | 用于苯并氧氮杂䓬恶唑烷酮化合物的制备的方法 | |
| TW202508560A (zh) | 製備p13k抑制劑之方法 | |
| WO2023237651A1 (en) | Method for the preparation of a 3,6-dihydro-2h-1,3,4-oxadiazin-2-one | |
| CN119731186A (zh) | Tyk2抑制剂 | |
| CN121419973A (zh) | Malt1抑制剂 | |
| CN114746410A (zh) | 用于生产式(i)的方法和中间体 | |
| Khan | Total synthesis and characterization of breitfussins A and B | |
| HK40076657A (en) | Process and intermediates for the production of formula (i) | |
| WO2015110467A1 (en) | Process for the preparation of substituted n-(5-benzenesulfonyl-1h-indazol-3-yl)-benzamides |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication |