CN1217935A - Medicinal ointment for bone fracture and injury of muscle and tendon and preparing method therefor - Google Patents
Medicinal ointment for bone fracture and injury of muscle and tendon and preparing method therefor Download PDFInfo
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- CN1217935A CN1217935A CN 98110530 CN98110530A CN1217935A CN 1217935 A CN1217935 A CN 1217935A CN 98110530 CN98110530 CN 98110530 CN 98110530 A CN98110530 A CN 98110530A CN 1217935 A CN1217935 A CN 1217935A
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Abstract
An exterior-applied plaster for treating the injure in tendons and bones, the injure from falls, fracture, contusions and strains, and ischias is prepared from 7 Chinese-medicinal materials such as notoginseng, dispacus root, peach kernel, sufflower, frankincense, etc. and features easy suction, quick acesodyne and detumescence, promoting bone healing, durable action and high curative effect.
Description
The present invention is preparation and the preparation method technical field that a kind of Chinese medicine plaster " bone founds peaceful cream " for the treatment of muscle and tendon injury injury of the bone disease belongs to Chinese medicine.
The muscle and tendon injury injury of the bone is that the soft tissue and the skeleton of human limb and metastomium is subjected to the damages that reason caused such as external violence or chronic strain, after the muscle and tendon injury, then take on and to lift at shoulder, knee joint then knee joint can not bend and stretch, fracture dislocation or osteopathia often cause the damage of muscle, sometimes union of fracture, still leave over the damage of muscle after the dislocation reduction, the fracture back is because bone break the muscle wound, fracture has pain and tenderness in various degree, local swelling, ecchymosis, malfunction appears in limbs, all gently then life inconvenience of suffering from above disease, heavy then LOM, and at present many for the medicine of muscle and tendon injury injury of the bone disease, how to develop a kind of better effects if, use more convenient, low-cost medicine external preparation imperative.
CN1049970A saves a kind of prescription and method for making thereof of Dressed plaster, and this invents for bones and muscles injury, though fracture etc. have certain curative effect, his DeGrain is short action time, and alleviating pain and detumescence is slow.Purpose of the present invention just provides a kind of with low cost, and alleviating pain and detumescence is rapid, and acting duration is long, portably uses convenient and safe effective external black plaster " bone is upright peaceful " cream and preparation method thereof.Main contents of the present invention: " bone is upright peaceful " cream is that raw material is made with the Chinese herbal medicine, and its constituent percentage by weight is as follows:
Rhizoma Chuanxiong 1-2% Pheretima 1-2% Radix Dipsaci 1-2% Cortex Eucommiae 1-2%
Rhizoma Drynariae 1-2% Herba Taxilli 1-2% Fructus Psoraleae 1-2% Radix Angelicae Sinensis 0.5-1.5%
Olibanum 0.5-1.5% Myrrha 0.5-1.5% Sanguis Draxonis 0.5-1.5%
Hirudo 0.5-1.5% Radix Rehmanniae Preparata 0.5-1.5% catechu 0.5-1.5%
Radix Notoginseng 0.5-1.5% Semen Persicae 0.5-1% Radix Achyranthis Bidentatae 0.5-1% Rhizoma Gastrodiae 0.5-1%
Polyporus 0.5-1% Rhizoma Corydalis 0.5-1% Lignum Aquilariae Resinatum 0.5-1%
Flos Carthami 0.1-0.5% Oleum Sesami 50-60% Plumbum preparatium 20-30%
Preparation method of the present invention comprises the steps:
1. soak: medicine is weighed accurately by prescription weight, go into Pheretima, Radix Rehmanniae Preparata, Radix Dipsaci, the Cortex Eucommiae, Herba Taxilli, Polyporus, Hirudo, Rhizoma Gastrodiae, Radix Achyranthis Bidentatae earlier, medicine such as Semen Persicae, Rhizoma Corydalis soaks in Oleum Sesami and (soaked spring 5 days, soaked summer 2 days, soaked autumn 7 days, soaked winter 10 days), the Lignum Aquilariae Resinatum, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Fructus Psoraleae, the four Chinese medicine that contain volatile component extract volatile oil with steam distillation earlier.
2. the fried oil of getting it filled:
The medicine that soaked oil is heated to spice with slow fire earlier reenters prescribe medicine medicinal residues Lignum Aquilariae Resinatum, Radix Angelicae Sinensis, Fructus Psoraleae, Rhizoma Chuanxiong when withered and yellow, temperature is no more than 220 ℃, fried sallow to the outside dark brown of spice inside, but the carbonization blackening is not advisable, and is cold slightly from fire, removes slag to filter promptly to get medicine oil.
3. oil refining: the fluid after removing slag, heating is tempered, and refines to the white to the greatest extent cigarette of black smoke, and the medicine oil droplet shows when dripping into pearl in water that oil is smelt.
4. pilling and pasting, the oil that refining is good is sieved into the Plumbum preparatium slowly, constantly stirs with waddy and trembles, in case the red heavy the bottom of a pan, emit to the greatest extent to white cigarette, and medicine oil is taken out during for pitchy by brown stain and splashes on a small quantity in the cold water, and it is tack-free to take out ointment after the several seconds, and denseness is suitable.
5. releasing fire-toxin: after plaster was boiled into, impouring was got ready in the cold water, constantly stirred to get to give birth to after condensing and pinched pressure repeatedly, and make agglomerate, immersed in the cold water, changed water every day one time, soaked (15 days winters, 5 days summers) on the 7th
6. mix the fines medicine: get the plaster agglomerate and put in the container, melt in water-bath with slow fire, make temperature mix into fines medicine Radix Notoginseng in the time of 60-70 ℃, extracting solution concentrated solution and volatile oil behind Olibanum, Myrrha, Sanguis Draxonis, catechu, Flos Carthami, the steam distillation stir.
7. the stand is coated with: the plaster that takes by weighing constant weight spreads out in paper or cloth etc. to be mounted on the backing material, collects standby.
The present invention is that raw material is made with the Chinese herbal medicine, with Olibanum, Myrrha, Sanguis Draxonis, Semen Persicae, Flos Carthami blood circulation promoting and blood stasis dispelling, uses the Hirudo Lignum Aquilariae Resinatum, Rhizoma Corydalis, Rhizoma Chuanxiong, Radix Notoginseng, Pheretima, Radix Dipsaci, Rhizoma Drynariae, catechu, channels sootheing and network vessel quickening, regulating QI to relieve pain in the side.Warming YANG dehumidifying such as Herba Taxilli, Rhizoma Gastrodiae, Radix Angelicae Sinensis, the Cortex Eucommiae, Fructus Psoraleae, Radix Rehmanniae Preparata, liver and kidney tonifying, Polyporus promoting diuresis to eliminate damp pathogen, elimination limb swelling, disease is gone out from urine, the medicine-feeding compatibility uses, rheumatism is gone, swelling disappears, hepatic and renal function strengthens, the Plumbum preparatium mainly is to use its counteracting toxic substances in the side, removing dampness is antipruritic, be again the excipient of plaster simultaneously, the medicine of full side is auxilliary mutually for using, giving consideration to both the incidental and fundamental, the merit of playing blood circulation promoting and blood stasis dispelling, reunion of fractured tendons and bones, damp eliminating eliminating impediment, removing obstruction in the collateral to relieve pain altogether reaches the pain that causes thus for the muscle and tendon injury injury of the bone and has curative effect preferably.The preclinical pharmacology experiment shows through Shandong Prov. Inst. of Traditional Chinese Medicine: mice gives bone upright peaceful cream 1.5g 3g external application, show significant analgesia role, improve thermostimulation and cause the pain fault, turn round the body number of times due to the minimizing chemical irritation and obviously suppress the acute exudative inflammation reaction, it presses down scorching rate and reaches 35%, the chronic hyperplastic inflammation inflammatory reaction is also had the obvious suppression effect, and its suppression ratio reaches 30%, and obviously improves pituitrin induced mice microcirculation disturbance.
The test of pesticide effectiveness confirms that this product has good anti-inflammatory and antalgic, improve Circulation, its external application administration, drug action is obvious, the upright peaceful cream external application administration of bone no matter disposable still repeatedly the skin irritation test confirm that this product to the intact skin nonirritant, has slight stimulation to damaged skin, experimental result confirms, this product external application does not have damaged skin and is used for the treatment of corresponding disease and does not have skin irritation, and it makes medicine approach safety.
The acute toxicity test of this product dermatologic shows: this product external application administration reaches 60 times of (the clinical 30g/ day for human beings) no overt toxicity effects that 30g/kg is about clinical application, safety non-toxic under this medicine external application administration doses is described, confirm the clinical amount of drafting of this product, the external application administration belongs to safety range, skin anaphylactic test result is as seen: this product does not have the sensitization of skin effect to responsive animal Cavia porcellus, show through the long term toxicity test data: Cavia porcellus gives this product external application, to the general situation of Cavia porcellus, the hematology, blood biochemical is learned and the histopathology index does not all have obvious influence, confirms that the long-term external application of this medicine also do not have the overt toxicity effect.
Bone stands rather Hospital Attached to Shandong Chinese Medical Univ.'s clinical observation once, clinical 200 examples for the treatment of altogether of this group, and total effective rate reaches 100%, and curative effect is extremely remarkable, and various disease such as the muscle and tendon injury injury of the bone, sciatica are all obtained fine therapeutic effect.And, generally can shift to an earlier date 7-15 days sclerotin healings, and alleviating pain and detumescence is fast to fracture patient.
The present invention has that the extensive cost of raw material is low, craft science, constant product quality, effect is easy to use lastingly, evident in efficacy, this medicine can be used as muscle and tendon injury injury of the bone patient first-use drug.
Real examination example: manufacture method preparation method of the present invention comprises the steps:
1. soak: medicine is weighed accurately by prescription weight, earlier with Pheretima 500g, Radix Rehmanniae Preparata 300g, Radix Dipsaci 400g, Cortex Eucommiae 400g, Herba Taxilli 400g, Polyporus 200g, Hirudo 300g, Rhizoma Gastrodiae 200g, Radix Achyranthis Bidentatae 200g, medicines such as Semen Persicae 200g, Rhizoma Corydalis 200g soak in Oleum Sesami 15000g, (soaked spring 5 days, soaked summer 2 days, soaked autumn 7 days, soaked winter 10 days), the Lignum Aquilariae Resinatum 200g that contains volatile component, Rhizoma Chuanxiong 500g, Radix Angelicae Sinensis 300g, Fructus Psoraleae 400g, four Chinese medicine extract volatile oil with steam distillation earlier.
2. the fried oil of getting it filled:
The medicine that soaked oil is heated to spice with slow fire earlier reenters the prescribe medicine medicinal residues when withered and yellow, Lignum Aquilariae Resinatum, Radix Angelicae Sinensis, Fructus Psoraleae, Rhizoma Chuanxiong, temperature are no more than 220 ℃, fried sallow to the outside dark brown of spice inside, but the carbonization blackening is not advisable, cold slightly from fire, removing slag to filter promptly gets medicine oil.
3. oil refining: the fluid after removing slag, heating is tempered, and refines to the white to the greatest extent cigarette of black smoke, and the medicine oil droplet shows when dripping into pearl in water that oil is smelt.
4. pilling and pasting, the oil that refining is good is sieved into Plumbum preparatium 6500g slowly, constantly stirs with waddy, in case the red heavy the bottom of a pan, emit to the greatest extent to white cigarette, and medicine oil is taken out during for pitchy by brown stain and splashes on a small quantity in the cold water, and it is tack-free to take out ointment after the several seconds, and denseness is suitable.
5. releasing fire-toxin: after plaster was boiled into, impouring was got ready in the cold water, constantly stirred to get to give birth to after condensing and pinched pressure repeatedly, and make agglomerate, immersed in the cold water, changed water every day one time, soaked (15 days winters, 5 days summers) on the 7th
6. mix the fines medicine: get the plaster agglomerate and put in the container, melt in water-bath with slow fire, make temperature mix into fines medicine Radix Notoginseng 300g in the time of 60-70 ℃, extracting solution concentrated solution behind Olibanum 300g, Myrrha 300g, Sanguis Draxonis 300g, catechu 300g, Flos Carthami 100g, the steam distillation and volatile oil stir to be trembled evenly.
7. the stand is coated with: the plaster that takes by weighing constant weight spreads out in paper or cloth etc. to be mounted on the backing material, collects standby.
Claims (4)
1. " bone founds peaceful cream " of a muscle and tendon injury injury of the bone disease is characterized in that this plaster is that raw material is made with the Chinese herbal medicine, and its composition percentage ratio is as follows:
Rhizoma Chuanxiong 1-2% Pheretima 1-2% Radix Dipsaci 1-2% Cortex Eucommiae 1-2%
Rhizoma Drynariae 1-2% Herba Taxilli 1-2% Fructus Psoraleae 1-2% Radix Angelicae Sinensis 0.5-1.5%
Olibanum 0.5-1.5% Myrrha 0.5-1.5% Sanguis Draxonis 0.5-1.5%
Hirudo 0.5-1.5% Radix Rehmanniae Preparata 0.5-1.5% catechu 0.5-1.5%
Radix Notoginseng 0.5-1.5% Semen Persicae 0.5-1% Radix Achyranthis Bidentatae 0.5-1% Rhizoma Gastrodiae 0.5-1%
Polyporus 0.5-1% Rhizoma Corydalis 0.5-1% Lignum Aquilariae Resinatum 0.5-1%
Flos Carthami 0.1-0.5% Oleum Sesami 50-60% Plumbum preparatium 20-30%
2. require the percentage by weight of described wherein each raw material can be as follows according to right 1:
Rhizoma Chuanxiong 1.9% Pheretima 1.9% Radix Dipsaci 1.4% Cortex Eucommiae 1.4%
Rhizoma Drynariae 1.4% Herba Taxilli 1.4% Fructus Psoraleae 1.4% Radix Angelicae Sinensis 1.0%
Olibanum 1.0% Myrrha 1.0% Sanguis Draxonis 1.0% Hirudo 1.0
Radix Rehmanniae Preparata 1.0% catechu 1.0% Radix Notoginseng 1.0% Semen Persicae 0.8%
Radix Achyranthis Bidentatae 0.8% Rhizoma Gastrodiae 0.8% Polyporus 0.8% Rhizoma Corydalis 0.8%
Lignum Aquilariae Resinatum 0.8% Flos Carthami 0.8% Oleum Sesami 53% Plumbum preparatium 23%
3. " bone founds peaceful cream " according to right 1, the 2 described treatment muscle and tendon injury injury of the bones is characterised in that said medicament is a said black plaster dosage form on the pharmaceutics.
4. the preparation method according to right 3 described " bone founds peaceful cream " is characterized in that
(1) soaks: medicine is weighed accurately by prescription weight, go into Pheretima, Radix Rehmanniae Preparata, Radix Dipsaci, the Cortex Eucommiae, Herba Taxilli, Polyporus, Hirudo, Rhizoma Gastrodiae Radix Achyranthis Bidentatae earlier, medicine such as Semen Persicae, Rhizoma Corydalis soaks in Oleum Sesami and (soaked spring 5 days, soaked summer 2 days, soaked autumn 7 days, soaked winter 10 days), contain the Lignum Aquilariae Resinatum of volatile component, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Fructus Psoraleae, four Chinese medicine extract volatile oil with steam distillation earlier.
(2) the fried oil of getting it filled:
Only the medicine that soaked oil is heated to spice with slow fire earlier and reenters the prescribe medicine medicinal residues when withered and yellow, Lignum Aquilariae Resinatum, Radix Angelicae Sinensis, Fructus Psoraleae, Rhizoma Chuanxiong, temperature are no more than 220 ℃, fried sallow to the outside dark brown of spice inside, but not the carbonization blackening be advisable from fire cold slightly remove slag to filter promptly get medicine oil.
(3) oil refining: the fluid after removing slag, heating is tempered, and refines to the white to the greatest extent cigarette of black smoke, and the medicine oil droplet shows when dripping into pearl in water that oil is smelt.
(4) pilling and pasting, the oil that refining is good is sieved into the Plumbum preparatium slowly, constantly stirs with waddy and trembles, in case the red heavy the bottom of a pan, emit to the greatest extent to white cigarette, and medicine oil is taken out during for pitchy by brown stain and splashes on a small quantity in the cold water, and it is tack-free to take out ointment after the several seconds, and denseness is suitable.
(5) releasing fire-toxin: after plaster was boiled into, impouring was got ready in the cold water, got to give birth to repeatedly after constantly stirring is condensed to propose, and made agglomerate, immersed in the cold water, changed water every day one time, soaked (15 days winters, 5 days summers) on the 7th
(6) mix the fines medicine: get the plaster agglomerate and put in the container, melt in water-bath with slow fire, make temperature mix into fines medicine Radix Notoginseng in the time of 60-70 ℃, extracting solution concentrated solution behind Olibanum, Myrrha, Sanguis Draxonis, catechu, Flos Carthami, the steam distillation and volatile oil stir to be trembled evenly.
(7) stand is coated with: the plaster that takes by weighing constant weight spreads out in paper or cloth etc. to be mounted on the backing material, collects standby.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98110530 CN1217935A (en) | 1998-10-28 | 1998-10-28 | Medicinal ointment for bone fracture and injury of muscle and tendon and preparing method therefor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98110530 CN1217935A (en) | 1998-10-28 | 1998-10-28 | Medicinal ointment for bone fracture and injury of muscle and tendon and preparing method therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1217935A true CN1217935A (en) | 1999-06-02 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 98110530 Pending CN1217935A (en) | 1998-10-28 | 1998-10-28 | Medicinal ointment for bone fracture and injury of muscle and tendon and preparing method therefor |
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| Country | Link |
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| CN (1) | CN1217935A (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1081068C (en) * | 1999-12-15 | 2002-03-20 | 牛彦明 | Traditional Chinese medicine for treating ischialgia neuralgia |
| CN1321654C (en) * | 2004-01-13 | 2007-06-20 | 吴占亨 | Drink of Chinese angelica and read-rooted salvia root |
| CN100446796C (en) * | 2005-08-25 | 2008-12-31 | 闫瑞锋 | Externally applied pharmaceutical for bone fracture |
| CN101244138B (en) * | 2008-03-05 | 2010-12-29 | 王振勤 | Externally used traditional Chinese medicine preparation for treating frostbite |
| CN103845458A (en) * | 2013-02-17 | 2014-06-11 | 张骞 | Traditional Chinese medicinal ointment for treating early swelling due to calcaneal fracture |
| CN109908321A (en) * | 2019-04-25 | 2019-06-21 | 王明良 | A kind of formula of plaster and preparation method thereof |
-
1998
- 1998-10-28 CN CN 98110530 patent/CN1217935A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1081068C (en) * | 1999-12-15 | 2002-03-20 | 牛彦明 | Traditional Chinese medicine for treating ischialgia neuralgia |
| CN1321654C (en) * | 2004-01-13 | 2007-06-20 | 吴占亨 | Drink of Chinese angelica and read-rooted salvia root |
| CN100446796C (en) * | 2005-08-25 | 2008-12-31 | 闫瑞锋 | Externally applied pharmaceutical for bone fracture |
| CN101244138B (en) * | 2008-03-05 | 2010-12-29 | 王振勤 | Externally used traditional Chinese medicine preparation for treating frostbite |
| CN103845458A (en) * | 2013-02-17 | 2014-06-11 | 张骞 | Traditional Chinese medicinal ointment for treating early swelling due to calcaneal fracture |
| CN109908321A (en) * | 2019-04-25 | 2019-06-21 | 王明良 | A kind of formula of plaster and preparation method thereof |
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