CN1209093C - Packaged scalp cosmetic compositions - Google Patents
Packaged scalp cosmetic compositions Download PDFInfo
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- CN1209093C CN1209093C CN 01816186 CN01816186A CN1209093C CN 1209093 C CN1209093 C CN 1209093C CN 01816186 CN01816186 CN 01816186 CN 01816186 A CN01816186 A CN 01816186A CN 1209093 C CN1209093 C CN 1209093C
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4933—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having sulfur as an exocyclic substituent, e.g. pyridinethione
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/006—Antidandruff preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/24—Thermal properties
- A61K2800/242—Exothermic; Self-heating; Heating sensation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/24—Thermal properties
- A61K2800/244—Endothermic; Cooling; Cooling sensation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/12—Preparations containing hair conditioners
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
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- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
Abstract
Disclosed are packaged leave-on cosmetic compositions for direct application to the scalp, comprising 1) a leave-on scalp cosmetic composition that is substantially free of cleansing surfactants and contains by weight of the leave-on scalp cosmetic composition i) from about 40% to about 99% by weight of a volatile liquid having a vapor pressure greater than 23.7mmHg as measured at 25 DEG C , ii) from about 0.005% to about 20% by weight of a skin active agent, and iii) from about 0.1% to about 20% by weight of a moisturizing material, preferably a liquid humectant, and 2) a package within which the scalp cosmetic composition is contained, wherein the package has a plurality of openings through which the leave-on scalp cosmetic composition is applied directly to the scalp. It has been found that the packaged compositions of the present invention can provide improved scalp moisturization and improved deposition of the skin active agent on the skin, without unduly affecting hair cosmetics.
Description
Invention field
The present invention relates to contain leave, the humidification cosmetic composition of skin activity material, wherein said composition is applied directly on the scalp by being suitable for direct applied application system.This packaged composition provides beneficial effects such as the scalp humidification that improves and skin activity electrodeposition substance.
Background of invention
The anti-dandruff product is known, and can buy on the consumer market usually.Many these products are shampoo or the hair oil form appears on the market, wherein contain the anti-dandruff composition, for example Zinc Pyrithione, triclosan, Amolden MCM 400, glycyrrhizic acid dipotassium salt, glycyrrhizic acid one ammonium, allantoin, sulphur-containing substance, isopropyl methyl phenol, salicylic acid and similar other material.
The hair of anti-dandruff or scalp nourishing agent are particularly useful, consumer can use the anti-dandruff nourishing agent to reach satisfied anti-dandruff effect, and the care institution of also selecting to be specifically designed to its hair type of consumer needs but not only in order to control or treat the required shampoo of the dandruff but then.Final result is peels off and pruritus relevant with dandruff hair with control of hair caring effect that reaches good.These anti-dandruff nourishing agents often are liquid, aqueous, and wherein the anti-dandruff active substance dissolves or is dispersed in the aqueous carrier, and this carrier contains water and is up to the chainlet alcohol carrier liquid of 80% weight.
Yet the hair of many anti-dandruffs and scalp nourishing agent can make the scalp overdrying that becomes, therefore produce to a certain extent with nourishing agent in the anti-dandruff effect opposite effect of anti-dandruff active substance.These nourishing agents often contain the volatile vehicle of high percentage ratio, ethanol for example, be intended in the application process or after using for scalp provides feel cool, but also can make skin be tending towards dry simultaneously, especially after using repeatedly.Also there is other the problem that contacts with hair in these nourishing agents in application process, and in some cases hair caring are had negative effect.
Have been found that the hair and the scalp nourishing agent that contain anti-dandruff or other skin activity material, hereinafter be called scalp cosmetic compositions, can prepare and be applied on the scalp, and do not make the scalp overdrying that becomes, and can too not influence hair caring.This can contain the leave compositions realization of following component by preparation: the about 0.1% humidification material to about 20% weight, preferred liquid wetting agent, about 0.005% anti-dandruff or other skin activity material to about 20% weight, with about 40% volatile liquid to about 99% weight, wherein said composition is substantially free of cleansing surfactants, and is applied directly on the scalp.
Find that also scalp cosmetic compositions of the present invention can be applied directly on the scalp, so not only improved the wettability of skin, also improved the deposition of skin activity material on scalp.Said composition preferably is applied directly on the scalp with applicator or other delivery system with a plurality of openings, and said composition is applied directly on the scalp by these openings.Compositions is applied directly on the scalp and can realizes by using suitable applicator or other delivery system, and can too not influence hair caring.
Therefore, the purpose of this invention is to provide and improved that the skin activity material is sent scalp and the compositions and the method that can too not influence hair caring.Another object of the present invention is the humidification effect to scalp that improvement also is provided when reaching such skin activity substance delivery, particularly when the skin activity material is the anti-dandruff material.A further object of the present invention is, contains the leave preparation of volatile liquid, anti-dandruff or other skin activity material and humidification material, preferred liquid wetting agent by direct application, and all these components directly are delivered to required area of scalp.
Summary of the invention
The present invention relates to be applied directly to the leave-on cosmetic compositions of the packing on the scalp.These packaged composition comprise 1) the leave scalp cosmetic compositions, said composition is substantially free of cleansing surfactants, but contain i in this leave scalp cosmetic compositions weight) about 40% volatile liquid to about 99% weight, the vapour pressure that this volatile liquid records 25 ℃ of temperature is greater than 23.7 millimetress of mercury, ii) about 0.005% skin activity material to about 20% weight, iii) about 0.1% humidification material to about 20% weight, the preferred liquid wetting agent, with 2) packing of this scalp cosmetic compositions is equipped with or is assigned, wherein this packing has a plurality of openings, and this leave scalp cosmetic compositions is applied directly on the scalp by these openings.
Have been found that packaged composition of the present invention can provide the scalp humidification of improvement and deposition or the performance of skin activity material on skin of improvement, and within reasonly influence hair caring.
Detailed Description Of The Invention
Packaged scalp cosmetic compositions of the present invention relates to following basic restriction: 1) volatile carrier liquid, 2) anti-dandruff or other skin activity material, 3) humidification material and 4) said composition is applied directly to applicator or packaging system on the scalp.Above each bar restriction will be described hereinafter in more detail.
Except as otherwise noted, term used herein " volatile " is meant such material, they are liquid under environmental condition, the vapour pressure of the vapour pressure that records 25 ℃ of temperature water during greater than 25 ℃ of temperature, preferably its vapour pressure greater than about 25 millimetress of mercury, more typical its vapour pressure greater than about 35 millimetress of mercury.On the contrary, except as otherwise noted, term used herein " nonvolatile " is meant solid or liquid substance, the vapour pressure of the water that the vapour pressure that they record 25 ℃ of temperature records when being equal to or less than 25 ℃ of temperature, and promptly the vapour pressure 25 ℃ of temperature is equal to or less than 23.7 millimetress of mercury.
Term used herein " leave " is meant cosmetic composition of the present invention, and be meant said composition to be applied to required skin area and need not to rinse subsequently or have one's hair wash, said composition kept after application at least about 1 hour, and more typical is the method that keeps after using at least about 6 hours.Following compositions got rid of particularly in term " leave ", for example shampoo, skin cleansing compositions and other similar compositions, and these compositionss are applied directly to required body region, immediately wash off, perhaps flush away in a few minutes after application.
Except as otherwise noted, term used herein " environmental condition " is meant the ambient conditions of about 1 atmospheric pressure (1atm), about 50% relative humidity and about 25 ℃ of temperature.Except as otherwise noted, all values as herein described, measure and measure all and under environmental condition, obtain.
Packaged scalp cosmetic compositions of the present invention is substantially free of cleansing surfactants.In context, term " is substantially free of " and is meant that this packaged scalp cosmetic compositions contains the cleansing surfactants that is less than 5%, preferably is less than 2% weight.Yet, should be appreciated that said composition can contain this surfactant that is less than 5% weight, condition is that this surfactant is used for stabilization formulations or is used to improve the non-clean-up performance of said composition.
Packaged scalp cosmetic compositions of the present invention is applied directly on the scalp.In context, " directly use " is meant that said composition mainly is applied directly on the scalp but not on the hair, preferably the applicator by having a plurality of openings or other packaging system are used, and said composition is by these openings by being applied directly in applicator or other packaging system on the scalp but not on the hair.Should directly use the typical case comprise the part hair that is applied to scalp and the most approaching or vicinity scalp or dry on, but preferably also specifically, the similar nourishing agent or the shampoo that do not comprise the compositions routine are applied on hair or the scalp like that, and this conventional method is with hands or other flexible substrate product to be applied on hair and the scalp, then said composition to be rubbed all over hair to required area of scalp.
Packaged scalp cosmetic compositions of the present invention can comprise, comprises or consist essentially of the neccessary composition and the restriction of this invention as herein described, and other effect that maybe should use of any additional or optional ingredients, component or restriction as herein described.
Except as otherwise noted, all percents used herein, umber and ratio are all in the weight of scalp cosmetic preparation in the packaged composition.Except as otherwise noted, all these weight relevant with ingredients listed all based on the content of concrete composition, therefore do not comprise solvent, carrier, by-product, filler or other microcomponent that may comprise in the commercially available material.
The skin activity material
Packaged scalp cosmetic compositions of the present invention contains anti-dandruff or other skin activity material that is enough to provide required skin activity effect.Any anti-dandruff or other skin activity material are known, are perhaps providing the effectiveness aspect anti-dandruff or other skin activity effect to be applicable to the present composition.Skin activity material in the present composition or reagent can be liquid forms solubilising or dispersive, or solubilising or the dispersed solids form.
Skin activity material in the packaged scalp cosmetic compositions of the present invention is prepared with the composition of variable concentrations, but accounts for about 0.005% to about 20%, more typical about 0.01% to about 10% even more typical about 0.05% to about 7% of scalp cosmetic compositions weight usually.Concentration will change according to following factor: the degree of the safe and effective concentration of determining of selected particular skin active substance, required skin activity beneficial effect or type etc.The limiting examples that is applicable to skin activity material of the present invention comprises the anti-dandruff active substance, steroid antiinflammatory (for example hydrocortisone), non-steroidal anti-inflammatory agents, the irritation active substance, insecticide (for example is used to control louse, flea, the material of tick or other insecticide), the plant sterol of plant substrates and derivant thereof (cupreol for example, campesterol, stigmasterol), feel nice and cool or the realizable material of other skin, antimicrobial except that the anti-dandruff active substance, anesthetis, hydryllin, astringent, enzyme, vitamin, the natural on-off cycles of hair growth active substance, the topical remedy of sunscreen and other similar known substance or other effect or non-pharmaceutically active substance.
Comprise butanols peperonal (peperonyl butoxide), Pyrethrum extract, imidacloprid topical solution, gamma hch (benzene hexachloride), organophosphorus ester (Malathion), natural pyrethrin, pyrethroid (for example permethrin) and any other is known or other effect, be used to control or treat skin, hair or fur to resist the material of insecticide as the limiting examples of the insecticide of skin activity material, described insecticide is flea, louse and other insecticide.
The limiting examples that is used for skin activity enzyme of the present invention comprises oxidoreductase, transferring enzyme, lyase, hydrolytic enzyme, isomerase, ligase and similar other enzyme.
The skin activity material can comprise selected alleviation antiinflammatory, and its concentration is to account for about 0.01% to about 5.0%, more preferably from about 0.05% to about 3.0% of scalp cosmetic compositions weight.In this article, alleviate the anti-inflammatory activity material be meant except that the steroid antiinflammatory, help alleviation and reduce skin irritant any material.The limiting examples of this active substance comprises pantothenic acid derivative, pantothenic acid ether, allantoin or its combination, the 01 derivatives of pantothenic acid preferably, and pantothenylol (comprising d-pantothenylol and l-pantothenylol) for example,
CTFA Cosmetic Ingredient HandbookDescribed some example in (The Cosmetic, Toiletry and FragranceAssociation.Inc.pp.272-273,1992), these descriptions are combined in herein as a reference.Pantothenylol also can be used as wetting agent, and when said composition did not contain other wetting agent, pantothenylol should be considered to be used to define the wetting agent of the present composition.Particularly preferably be allantoin, vitamin E oil, and combination.
The skin activity material is preferably the anti-dandruff active substance, most typical is antimicrobial anti-dandruff active substance, and its concentration in compositions is about 0.001% to about 5%, more preferably from about 0.01% to about 3% even more preferably from about 0.05% to about 1% of composition weight.Preferred antimicrobial anti-dandruff active substance comprises Fungicidal active substance, for example pyrrole sulfosalt, Octopirox, ketoconazole, Climbazole, ring pyrrole department, Terbinafine, itraconazole and sulfur or sulfur-bearing active substance, for example selenium sulfide.Zinc Pyrithione (ZPT) most preferably, its concentration is 0.005% to 2%, more preferably from about 0.005% to about 0.5% of composition weight.
Selenium sulfide is the antimicrobial anti-dandruff active substance that preferably is used for the present composition, and its valid density is about 0.001% to about 5.0%, preferred about 0.01% to about 2.5%, more preferably from about 0.05% to about 1.0% of scalp cosmetic compositions weight.Selenium sulfide is counted as the chemical compound with one mole of selenium and two molar sulphur usually, although also can be the SexSy of ring structure, wherein x+y=8.Selenium sulfide is that personal care field is known, and is described in for example United States Patent (USP) 2,694,668; United States Patent (USP) 3,152,046; United States Patent (USP) 4,089,945; With United States Patent (USP) 4,885, in 107, these are described in conjunction with in the present invention as a reference.
Other sulfur or sulphur-containing substance also can be as the anti-microbial active matter in the scalp cosmetic compositions, and its concentration is about 0.001% to about 5.0%, preferred about 0.1% to about 5.0%, more preferably from about 1.0% to about 5.0% of scalp cosmetic compositions weight.
Pyrrole sulfur anti-microbial active matter, particularly 1-hydroxyl-2-pyrithione are highly preferred, as to be used for scalp cosmetic compositions anti-dandruff active substances.Preferred pyrrole sulfosalt is the salt that is formed by heavy metal, described heavy metal such as zinc, stannum, cadmium, magnesium, aluminum and zirconium.Zinc salt is most preferred, particularly the zinc salt of 1-hydroxyl-2-pyrrole sulfur (Zinc Pyrithione, ZPT).Other cation, for example sodium also is suitable for.Particularly preferably be the 1-hydroxyl-2-pyrrole sulfosalt of plate-like particles form, wherein particulate mean size be up to about 20 microns, preferably be up to about 8 microns, most preferably be up to about 5 microns.Pyrrole sulfur anti-microbial active matter is that the hair care field is known, and is described in for example United States Patent (USP) 2,809,971; United States Patent (USP) 3,236,733; United States Patent (USP) 3,753,196; United States Patent (USP) 3,761,418; United States Patent (USP) 4,345,080; United States Patent (USP) 4,323,683; United States Patent (USP) 4,379,753; With United States Patent (USP) 4,470, in 982, these are described in conjunction with in the present invention as a reference.
Other instantiation that contains rolled tin skin active substance that is used for the present composition and method comprises Zinc Pyrithione; zinc acetate; acetyl group methane-disulfonic acid zinc; aspartic acid zinc; Firebrake ZB; zinc carbonate; zinc chloride; zinc citrate; DNA zinc; formaldehyde sulfoxylate zinc; zinc gluconate; zinc glutamate; hydrolytic collagen zinc; zinc lactate; Dodecanoic acid, zinc salt; Grillocin P 176; zinc neodecanoate; Hexadecanoic acid, zinc salt; PCA zinc; ten pentaene tricarboxylic acids zinc; zinc ricinate; zinc ricinate; resin acid zinc; zinc stearate; zinc sulfate; Zinc Undecenoate; zinc oxide; lactobionic acid zinc, and combination.
The skin activity material that is used for packaged composition of the present invention can comprise that any its adds the material (being also referred to as " hair growth active substance " in this article) that the hair growth regulating action can be provided after compositions.In context, term " hair growth adjusting " comprises stimulating hair growth; Stimulate the hair density; Prevent, reduce, stop and/or postpone and lose hair; Prevent, reduce, stop and/or to postpone hair thinning; Increase hair growth speed; Induce more multiple silk to form; Increase the hair diameter; Prolong hair; Hair follicle is become terminal capsule by the hair capsule; Induce the formation of hair capsule; With capsule by be converted into resting stage the growth animated period (increase thus growth animated period capsule and resting stage capsule population proportion); Promote capsule by developing into later growth animated period than growth animated period early; Cause that the growth animated period transforms to growth mid-term; The treatment alopecia; And combination in any.
Preferred hair growth active substance comprises and contains zinc salt, for example as herein described those, lactobionic acid zinc particularly.Other hair growth active substance that is applicable to the present composition and method comprises United States Patent (USP) 6,124, those materials described in 362 (Bradbury etc.), and these are described in conjunction with in the present invention as a reference.
Volatile liquid
Packaged scalp cosmetic compositions of the present invention comprises the volatile carrier liquid that is suitable for being applied topically on the application on human skin.These liquid-carriers comprise any volatile liquid that is under environmental condition, the perhaps combination of any liquid-carrier, and these are combined in is volatile under the environmental condition, they are suitable for being applied topically to other zone of scalp or skin in addition.
In packaged scalp cosmetic compositions of the present invention, the content of volatile carrier liquid or carrier combinations is about 40% to about 99%, preferred about 50% to about 80%, more preferably from about 55% to about 80% even more preferably from about 60% to about 75% of scalp cosmetic compositions weight.
Volatile carrier liquid preferably comprises 2 to 8 carbon atoms, the monohydric alcohol of 2 to 4 carbon atoms more preferably from about, and preferred embodiment comprises ethanol, isopropyl alcohol, propanol, n-butyl alcohol, the tert-butyl alcohol, isobutanol, and combination.Most preferred ethanol.Other volatile carrier liquid also can be used for said composition, does not preferably contain the liquid-carrier of polysiloxanes, and they can use separately, perhaps uses with various compound modes, for example is used in combination with preferred monohydric alcohol described in the invention.The limiting examples of these other volatile carrier liquids comprises ester or the ether and the polysiloxanes etc. of volatile hydrocarbon liquid, polyhydric alcohol, monohydric alcohol or polyhydric alcohol, condition is that they have essential volatility as herein described, and is not the liquid wetting agent component of the present composition hereinafter described.
The humidification material
Packaged scalp cosmetic compositions of the present invention contains one or more humidification materials, so that said composition has the humidification of improvement and/or the beneficial effect of minimizing scale.The humidification material can be any known or the material of other effect is arranged aspect the skin moisturizing providing, and preferably is restricted to following material, and they make compositions have scalp humidification as described herein or instantaneous scale minimizing value.
The humidification material that is used for packaged scalp cosmetic compositions of the present invention is preferably the liquid wetting agent.The wetting agent that is fit to comprises any liquid hygroscopic material, and they are known or the material that other effect is arranged aspect the effect of leave compositions skin moisturizing is being provided.The concentration of this material will change according to following factor: the concrete wetting agent in choice of formulation and the preparation, but this concentration is typically about 0.1% to about 20%, more typical about 0.5% to about 15%, most preferably from about 1.0% to about 10% of scalp cosmetic compositions weight most.
The liquid wetting agent that is applicable to packaged scalp cosmetic compositions of the present invention is water-soluble liquid normally, and their dissolubility in 25 ℃ of temperature water are at least 50% weight.Many these wetting agents have the hydroxyl of one or more connections, its limiting examples comprises the liquid poly alkylene glycol, for example (for example molecular weight is about 200 to about 600 for polypropylene glycol and diethylene glycol or Polyethylene Glycol, for example PEG-4, PEG-6, PEG-8, PEG-12), ethohexadiol, hexanediol, butanediol, glycerol, propylene glycol, dipropylene glycol, tripropylene glycol, polypropylene-5-lauryl ether-5, polyglycereol coconut palm acid esters, sorbitol, fructose, glycine, inositol, pantothenylol, and combination.
The concrete limiting examples of suitable wetting agent comprises Lubrajel Oil
(glyceryl polymethacrylates and propylene glycol), Glucquat
125 (lauryl methyl gluceth-10 hydroxypropyldimoniumchloride), Glucam
E-10 (methyl gluceth-10), Glucam
E-20 (methylgluceth-20), Glucam
P-10 (PPG-10 methyl glucose ether), Glucam
P-20 (PPG-20 methyl glucose ether), sodium lactate, PCA sodium, Schercomid LME (Lactamide MEA), Clearcol (dissolving collagen), Collasol M (dissolving collagen), Crolastin (elastin hydrolysis), Cromoist CS (sodium chrondroitin sulfate and hydrolytic collagen), Cromoist HYA (hydrolytic collagen and hyaluronic acid), Cromoist WHYA (hydrolyzed wheat protein and hyaluronic acid), Cromoist 0-25 (hydrolysis Herba bromi japonici), Cropeptide W (hydrolyzed wheat protein and hydrolyzed wheat starch), Crosilk 10,000 (hydrolyzed-silk), Crosilk Liquid (Silk Amino Acids), Crosilkquat (Cocodimonium hydroxypropylsilk amino acids), Crotein CAA/SF (collagen amino acid), Crotein HKP (hair-keratin (keatin) aminoacid and sodium chloride), Crotein HKP/SF (keratin aminoacid), Crotein MCAA (collagen amino acid), Hydrolactin 2500 (lactoalbumin hydrolysate), Hydrosoy 2000 (hydrolyzed soybean protein), Hydrotriticum
TM2000 (hydrolyzed wheat proteins), Hydrotriticum
TMWAA (Semen Tritici aestivi aminoacid), Reticusol (hydrolysis reticulin), Tritisol
TM(hydrolyzed wheat protein), Incromectant AMEA-100 (acetamide MEA), Incromectant AMEA-70 (acetamide MEA), Incromectant LMEA (acetamide MEA and lactamide MEA), Incromectant AQ (acetylamino oxypropyl trimethyl ammonium chloride (trimonium chloride)), Incromectant LQ (lacto oxypropyl trimethyl ammonium chloride), Gelatin NF, Lactil
(sodium lactate and PCA sodium, and glycine and fructose and carbamide and nicotinamide and inocitol and sodium benzoate and lactic acid).
The wetting agent that is used for packaged scalp cosmetic compositions preferably permeates the scalp skin surface, and promptly horny layer sucks moisture in those skin layers then, and the scalp humidification of improvement is provided after application thus.This wetting agent preferably has to help provide has the compositions of measuring as defined preferred skin moisturizing hereinafter.
Product form
Scalp cosmetic compositions of the present invention is a flowable liquids under environmental condition, and have about 20 centistokes to about 60,000 centistokes, preferred about 100 to about 20,000 centistoke (1mm
2/ s=1 centistoke) viscosity.These flowable liquids can take various forms, and comprise dispersion, multi-phase emulsion or suspension, perhaps single phase soln.
Have been found that, scalp cosmetic compositions is under environmental condition or service condition, the viscosity that should have product as described herein, so that it provides acceptable coating characteristics on being applied directly to scalp, particularly by applicator or when being applied directly on the scalp for other packing of direct scalp Application Design.Also find, have the scalp cosmetic compositions that contains zinc anti-dandruff active substance and should have at least 1,000 centistoke (1mm
2/ s=1 centistoke), preferred about 1,000 to about 20,000 centistoke (1mm
2/ s=1 centistoke) minimal viscosity so that required coating characteristics to be provided, and makes that containing zinc active material is evenly distributed in applied area of scalp in application process.
Product attribute
Scalp cosmetic compositions of the present invention provides following beneficial effect for scalp, for example alleviate pruritus, abirritate, humidification, minimizing scale, reduce the drying time on the scalp, and with other relevant beneficial effect of selected concrete skin activity material.According to selected active substance, these other beneficial effects can comprise hair growth (for example ZPT or other hair growth active substance), dandruff control or inhibition, antiinflammatory, antifungal or other anti-microbial effect etc.
Scalp cosmetic compositions of the present invention preferably provides one or more following performance characteristics, comprises that scale as defined herein reduces and scalp humidification value, it is characterized in that helping the product beneficial effect that provides mentioned above.Determine these performance characteristics according to defined method hereinafter.
1.
Initial scale reduces
Packaged scalp cosmetic compositions of the present invention provides the scalp humidification and the scale minimizing effect that improve, particularly for those scalp application regions of having carried out dandruff control or having eliminated.Providing because the short-term scale that the scalp humidification is produced reduces and (produce scale, the control of for example dandruff by continuous application by continuous application product and control scalp condition, and improving the deposition of anti-dandruff active substance) the long-term scale that produced reduces by two aspects, and said composition is all effective especially.
Packaged scalp cosmetic compositions preferably is provided at the initial scale of measuring when using back 5 minutes and reduces, and so that initial as herein defined scale minimizing value to be provided, this value is preferably at least about 40%, more preferably reduce at least about 50% scale.Initial scale minimizing value comes down to the tolerance that the visible scale in appointed area reduces percent, is the result of this zone cosmetic applications.Initial scale minimizing value be use or treatment after soon, effectively increase scalp humidity and reduce the relevant tolerance of visible scale flaking presentation with compositions.Measure instantaneous scale minimizing value according to following methodology.
According to the methodology that instantaneous scale reduces, wash lower limb during 3 days the normal bathing of each panelist before beginning to divide into groups; During cleaning, on lower limb, do not use the cream frost wetting agent of any kind.On every lower limb, mark several 3 * 7 centimetres zones with sharpie card mark pen then.Scalp cosmetic compositions (adding 0.1 milliliter with syringe) is locally applied to one of them marked region, and be coated in whole zone equably with the finger of band latex glove.Each panelist's a marked region in contrast, application product not on it.Use after 5 minutes, use D-Squame
Dish (22 millimeters transparent plates of standard, available from CUDerm Corporation, Dallas, Texas, U.S.A) the extruding area for treatment is removed then immediately, is pressed into the D-squame storage card then.Contrast (not receiving treatment) skin area repeats the step that this relates to the D-squame dish.Observe treatment and the scale on the D-squame dish of area for treatment not, and measure instantaneous scale minimizing value, as percentage rate with respect to scale quantity minimizing on the dish of not treatment contrast.
2.
The scalp humidification
Packaged scalp cosmetic compositions of the present invention comprises humidification material, preferred liquid wetting agent as indicated above, wherein this humidification material or wetting agent help to provide compositions, said composition has the effect of humidification scalp, and helps to reduce scale flaking and/or the pruritus that is caused by drying or irriate skin.The scalp humidification that is provided by scalp cosmetic compositions can be applied on the scalp moisture of skin of back in the time of about 4.0 hours and determines its characteristic by measuring said composition.
The scalp humidification that is used for the characteristic of definite present composition and method can be measured the skin moisturizing effect and indirect determination by after being applied to scalp cosmetic compositions on the lower limb.Carrying out this skin moisturizing by following method measures.All readings hereinafter described all obtain under 23 ℃ of temperature and 50% relative humidity.
According to the methodology that this paper humidification is measured, each panelist at first washes lower limb during 3 days the normal bathing before beginning to divide into groups; During cleaning, on lower limb, do not use the wetting agent or the cream frost of any kind.On every lower limb, mark several 3 * 7 centimetres zones with sharpie card mark pen.Before with any product treatment, five of marked region different points read the Skicon reading (Skicon-200, available from I.B.S.Co.Ltd. (Shizuoka-ken, Japan).By contacting with horny layer to avoid hair and to guarantee, use the hydration on Skicon evaluating skin surface with multiple spot probe measurement electrical conductivity (microhm or μ σ).Five Skicon readings before the product treatment are average, and as baseline, and the Skicon reading of the skin of will receiving treatment compares with it.
After obtaining the baseline reading, 0.1 milliliter of product is applied to the zone that obtains the baseline reading, and is coated in whole zone equably with the finger of band latex glove.With one of them marked region in contrast, in process of the test, application product on this Experimental Area not.Use after 4 hours, get five Skicon readings again in application and marked region.These 4 readings are average.Deduct the average baselining reading then from 4 hours reading meansigma methodss that obtained by the same application zone, the humidification that obtains increasing, this humidification are because due to this product of this area applications.Increase with this humidification compares with the increase that same not treatment through 4 hours contrasts the humidification that records then.On lower limb, the skin of receiving treatment is with the increase of not treating the skin moisturizing effect and expect that the increase of the skin moisturizing effect that similar products are used on scalp is relevant.This treatment is described its characteristic to being increased in relatively herein of humidification of not treating skin with scalp humidification value, and this value is the ratio that treatment increases the humidification of not treating skin.
Packaged scalp cosmetic compositions of the present invention preferably provides at least about 2.5, more preferably at least about 4.0 in addition more preferably at least about 6.0, be typically about 2.5 to about 10.0 scalp humidification value most.
Application system
Packaged scalp cosmetic compositions of the present invention is applied directly on the scalp, contacts with the initial of hair to reduce, and improves the deposition of skin activity material on scalp.Any known or other effective method or application system that product is applied directly on the scalp all are applicable to the present composition and method.
Packaged scalp cosmetic compositions of the present invention directly is applied on the scalp.In context, " directly use " is meant that said composition mainly is applied directly on the scalp but not on the hair, preferably the applicator by having a plurality of openings or other packaging system are used, and said composition is by these openings by being applied directly in applicator or other packaging system on the scalp but not on the hair.Should directly use the typical case comprise the part hair that is applied to scalp and the most approaching or vicinity scalp or dry on, but preferred and concrete is, the similar nourishing agent or the shampoo that do not comprise the compositions routine are applied on hair or the scalp like that, and this conventional method is with hands or other flexible substrate product to be applied on hair and the scalp, then said composition to be rubbed all over hair to required area of scalp.
Packaged scalp cosmetic compositions preferably uses the application system that comprises applicator or other packaging system to be applied directly on the scalp, wherein this application is directly finished by a plurality of openings, promptly directly cross hair and directly be coated on the scalp or near the position of scalp, like this, said composition just is applied directly on the scalp, although some products can contact near the dry of scalp surface with some.
The example that is used for the application system of the present composition and method comprises, the any packaging system that contains reservoir and a plurality of opening or additional teeth or other and reservoir connected components, in reservoir, contain said composition or compositions and pass this reservoir, compositions by appearing in the reservoir, and is applied directly to scalp surface by a plurality of openings or additional teeth or other and reservoir connected components.This packaging system preferably contains at least about 3 such openings or tooth, more typically has an appointment 3 to about 300 teeth, and certainly, the quantity of opening and tooth will change according to factors such as required applicator size, designs.Preferred opening is positioned at the end of tooth, i.e. terminal the and close position of using of reservoir.
Other suitable application system comprises the packing or the application system that can comprise or not comprise the compositions reservoir, but this packing or application system comprise comb or scalp brush, for example the part of comb or brush is dipped in scalp cosmetic compositions, and it is used on the scalp.
Optional member
Packaged scalp cosmetic compositions of the present invention can also comprise one or more and become known for taking care of hair or personal care product's optional components, condition be these optional members physically and chemically compatible with neccessary composition described herein, the performance that influences product perhaps within reason.The concentration of this optional components the most typical and be separately scalp cosmetic compositions about 0.001% to about 10% weight.
The limiting examples that is used for the optional components of scalp cosmetic compositions comprises dyestuff, emulsifying agent and surfactant, pH regulator agent, flavor chemistry product and spice, antiseptic, protein, sunscreen, vitamin (for example vitamin E oil), viscosity modifier, coloring agent, suspending agent or thickening agent (for example polyacrylic ester thickener) etc.
Other optional member comprises the realizable material of skin, the preferred nice and cool realizable material of skin, and its some limiting examples is described in United States Patent (USP) 4,230,688 (Rowsell etc.) and United States Patent (USP) 4,136, among 163 (Watson etc.), these describe combination in the present invention as a reference.The limiting examples of optional sensate matter comprises menthol, menthone glycerol acetal, methyl diisopropyl propionic acid amide., menthyl lactate, the Herba Menthae Oxy-1, the 2-propylene glycol, ethyl-formamide, the trimethyl butyramide, menthyl lactate, succinic acid one menthyl ester, the vanillyl butyl ether, the 1-isopulegol, eucalyptole, the cresotinic acid acid esters, Eucalyptus oil, carvone, oil of rosemary, oil of ginger, Oleum Caryophylli, ethyl menthane formamide, Camphora, eucolytol, Oleum menthae, and combination, its concentration is preferably about 0.01% to about 2.0% of composition weight, more preferably from about 0.01% to about 1.0%.
Except volatile vehicle liquid mentioned above, the optional nonvolatile vehicle liquid that contains of packaged scalp cosmetic compositions of the present invention.Nonvolatile vehicle can be any liquid-carrier, and they are known or are suitable for being applied on the scalp, wherein the optional nonvolatile vehicle of the selected concentration performance that influences product within reason.Optional nonvolatile vehicle liquid can be moisture or non-water, contain polysiloxanes or do not contain polysiloxanes, if but exist, then preferred aqueous carrier, it makes compositions have to be up to the water concentration of scalp cosmetic compositions weight about 50%, more preferably from about 5% to about 50% even more preferably from about 10% to about 40%.The optional limiting examples that is used for non-volatile liquid of the present invention is described in United States Patent (USP) 6,074, and among 655 (Fowler etc.), these are described and introduce the present invention as a reference.
Application process
Packaged scalp cosmetic compositions of the present invention is applied directly on the suitable skin area of scalp or other, and most compositions is with regard at first being applied directly on the skin but not on the hair like this.This application is preferably by using compositions packaging system or delivery system by mentioned earlier to realize, and this system contains a plurality of openings, and compositions is directly crossed hair by these openings and is applied directly on the scalp.Said composition is applied directly on the scalp with the amount that required humidification and/or skin activity beneficial effect effectively are provided.Consumption will change according to factors such as the needs of user and choice of formulation, but most typical consumption is each use about 0.1 and is charged to about 10 grams, about 0.5 gram of more typical each application to about 5 grams, and can be once a day or repeatedly be applied on the scalp wet or that do.
Preparation method
Packaged scalp cosmetic compositions of the present invention can be by any known or other otherwise effective technique preparation, these technology are suitable for the neccessary composition of compositions and any selected optional member combination, to form physically stable, to be suitable for the fluid composition of dermal application.According to known routine or other effective packing, filling or manufacture method, said composition is packaged in the direct application system.
For example, packaged scalp cosmetic compositions of the present invention can be mixed with O/w emulsion, wherein relates to O/w emulsion and with the preparation of the neutral Carbopol thickening of amino methyl propanol (AMP) product.
1. Carbopol Ultrez-10 (polyacrylate polymers derives from B.F.Goodrich) under stirring, medium level is mixed to complete hydration powder with deionized water.Continue to mix until Carbopol looking complete wetting and not agglomeration, and outward appearance is fuzzy slightly.
2. then other composition is added in the batch of material, use the alkali thickening, preferably add any water soluble materials, for example wetting agent, pantothenylol.Also add allantoin this moment.
3. prepare ZPT pre-composition (perhaps other similar skin activity material pre-composition) with ethanol or second alcohol and water then.In water, wetting agent, carbopol mixture, add ZPT, add oil phase or thickening carbopol (containing water) then.
4. in another pre-composition,, form oil-ethanol phase with oil soluble material (comprising alpha-tocopherol acetate, menthyl lactate, menthol, spice), ethanol, ethylene glycol and emulsifying agent combination.
5. under vigorous stirring, oil-ethanol is added to aqueous phase, forms the emulsion of white, emulsus outward appearance.
6. in the ratio of 0.85AMP, use in the amino methyl propanol (AMP-regulator) and emulsus outward appearance emulsion than 1 Carbopol of unit.Usually, with AMP and the premixing of part ethanol, with mix better and accelerate in and speed.In case the adding nertralizer continues to mix about 30 minutes, to guarantee to obtain uniform batch of material.
7. the gained scalp cosmetic compositions is packed and is included in the reservoir with 3 to 300 tooth/openings, described tooth/opening links to each other with reservoir and extends out from reservoir.Cosmetic composition in will packing then regularly directly is assigned on the scalp by tooth/opening, and keeps on scalp at least 1 to 6 hour and do not wash off.
Embodiment
Following non-limiting example has illustrated the scalp cosmetic embodiment of the packing that the present invention is concrete.Each compositions of enumerating all prepares the known method preparation of water alcohol liquid according to formulation art.Except as otherwise noted, all amounts of enumerating all are the percentage by weights in the scalp cosmetic compositions gross weight.
Then as mentioned above, each compositions of enumerating is packaged in the suitable dressing device, and is applied directly on the scalp by applicator.Said composition not rinsing at least 1 to 6 hour or do not remove after application from skin.Each compositions of enumerating provides skin activity electrodeposition substance with improvement, improved skin or scalp humidification and do not have too to influence the scalp application region of hair caring.
Each compositions of enumerating also uses the skin activity material except that the anti-dandruff active substance to prepare, and comprises steroid antiinflammatory (for example hydrocortisone), non-steroidal anti-inflammatory agents, insecticide, the antimicrobial except that anti-dandruff goods material, anesthetis, hydryllin, astringent, enzyme, vitamin and hair growth active substance (for example lactobionic acid zinc, Zinc Pyrithione).After directly using, each these again composition prepared provide the skin or the scalp humidification that improve, and the deposition of skin activity material on skin of improving.
Table 1: leave scalp cosmetic compositions
I | II | III | IV | V | VI | VII | |
Composition | Weight % | ||||||
Water, DRO | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount |
Carbomer (1) | 0.3 | 0.3 | 0.4 | 0.1 | |||
Carbomer (2) | 0.5 | - | |||||
Polyacrylamide (with) C13-14 isoparaffin (an) lauryl ether-7 (3) | - | 4.0 | 2.5 | ||||
Amino methyl propanol (4) | 0.26 | 0.285 | 0.34 | - | - | - | 0.13 |
Tetrahydroxypropyl second two (5) | - | - | - | 0.5 | - | - | |
Ethanol (6) | 55.0 | 50.0 | 55.0 | 55.0 | 55.0 | 60.0 | 45.0 |
Zinc Pyrithione (7) | 0.1 | 0.1 | 0.09 | 0.01 | 0.01 | 0.2 | 0.1 |
Zinc sulfate (8) | - | - | 0.01 | 0.1 | - | - | |
Zinc lactate (9) | - | - | - | - | - | 0.2 | - |
Menthyl lactate (10) | 0.35 | 0.1 | 0.25 | 0.5 | -0.5 | - | |
Menthol (11) | 0.15 | 0.1 | 0.25 | 0.25 | 0.25 | 0.25 | 0.5 |
Menthone glycerol acetal (12) | 0.5 |
Pantothenylol (13) | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 2.0 | 1.0 |
Tocopheryl acetate (14) | 0.5 | 1.0 | 1.0 | 1.0 | 1.0 | 2.0 | - |
PEG-60 castor oil hydrogenated (15) | 1.0 | 1.0 | 1.0 | 2.0 | |||
PEG-25 triolein (16) | - | - | - | - | 1.0 | - | - |
Hexanediol (17) | - | 1.0 | - | - | - | - | - |
Glycerol (18) | 5.0 | 5.0 | 5.0 | 5.0 | 5.0 | 4.0 | 3.0 |
Allantoin (19) | 0.05 | 0.05 | 0.08 | 0.08 | 0.1 | 0.01 | - |
Isoceteth-20(70%act.(20) | 0.71 | - | 0.1 | 0.1 | 2.0 | - | |
Cetearth-20(21) | 0.5 | - | |||||
Spice (22) | 0.30 | 0.30 | 0.30 | 0.30 | 0.30 | 0.30 | 0.30 |
Zinc oxide (23) | - | - | 0.01 | - | 0.01 | - | - |
1 Carbopol Ultrez 10, supplier: B.F.Goodrich 13 D pantothenylol, supplier: Hoffmann
LaRoche
2 Carbopol ETD 2020; Supplier: B.F. 14 alpha-tocopherol acetates, supplier: BASF
Goodrich
3 Sepigel 305, supplier: Seppic 15 Cremophor RH 60, supplier BASF
4 AMP regulators, supplier: Angus 16 Tagat TO, supplier: Goldsmidt
5 Neutrol TE, supplier: BASF 17 hexanediol, supplier: Van Waters ﹠amp;
Rodgers
6 200 proof, SDA 40-2 18 Superol USP, supplier: Procter
& Gamble
7 small pieces ZPT (2.5m), supplier: Arch 19 micronization allantoin, supplier: ICI
8 Whitco Zinc Stearate D.USP, supplier: Witco 20 Arlasolve 200L, supplier: ICI
9 Puramex ZN, supplier: Purac 21 CremaphorA20, supplier: BASF
10 Frescolate ML, supplier: Haarman ﹠amp; Reimer 22 spice, supplier: Haarman ﹠amp; Reimer
11 USP menthols, supplier: Haarman ﹠amp; Reimer 23 Z-cote HP1, supplier: BASF
12 Frescolat MGA, supplier: Haarman ﹠amp; Reimer
Table 2: leave scalp cosmetic compositions
VIII | IX | X | XI | XII | XIII | XIV | XV | |
Water, DRO | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount | In right amount |
Carbomer (1) | 0.3 | - | 0.4 | - | 0.1 | |||
Carbomer (2) | 0.5 | 0.5 | - | |||||
Polyacrylamide (with) C13-14 isoparaffin (an) lauryl ether-7 (3) | - | 0.5 | 1.0 | |||||
Amino methyl propanol (4) | 0.26 | - | 0.34 | - | - | - | 0.13 | |
Tetrahydroxypropyl ethylenediamine (5) | - | 0.5 | - | 0.5 | - | - | ||
Ethanol (6) | 55.0 | 50.0 | 55.0 | 55.0 | 55.0 | 60.0 | 45.0 | |
Selenium sulfide (7) | 0.05 | |||||||
Ketoconazole (8) | 0.1 | |||||||
Climbazole (9) | - | - | 0.05 | - | - | - | ||
Salicylic acid (10) | - | - | - | 3.0 | - | 0.2 | - | |
Pyrethrin (11) | 0.1 | |||||||
Protease, lipase mixt (12) | ||||||||
Hydrocortisone (13) | 1.0 | |||||||
Bacitracin zinc (14) | 0.1 | |||||||
Naphthalene ester (15) | 1.0 | |||||||
Menthyl lactate (16) | 0.25 | 0.1 | 0.25 | 0.25 | 0.25 | 0.50 | 0.1 | 0.5 |
Pantothenylol (17) | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 2.0 | 0.5 | 1.0 |
Tocopheryl acetate (18) | 0.5 | 1.0 | 1.0 | 1.0 | 1.0 | 2.0 | - | - |
PEG-60 castor oil hydrogenated (19) | 0.5 | 1.0 | 1.0 | 1.0 | 1.0 | 2.0 | - | - |
Glycerol (20) | 5.0 | - | 3.0 | 5.0 | 10.0 | 1.0 | 3.0 | |
Sorbitol (21) | 4.0 | - | - | 1.0 | - | - | ||
Polymethylacrylic acid glyceryl ester and propylene glycol (22) | 5.0 | - | - | 3.0 | - | |||
Methyl Glyceth-20 (23) | 1.0 | - | - | |||||
Isoceteth-20(70%act.)(24) | 0.71 | 0.7 | 0.7 | 0.1 | 0.1 | 2.0 | - | - |
Spice (25) | 0.30 | 0.30 | 0.30 | 0.30 | 0.30 | 0.30 | 0.30 |
1 Carbopol Ultrez 10, supplier: B.F.14 antibacterial
Goodrich
2 Carbopol ETD 2020; Supplier: B.F. 15 antifungal
Goodrich
3 Sepigel 305, supplier: Seppic 16 Frescolate ML, supplier: Haarman ﹠amp;
Reimer
4 AMP regulators, supplier: Angus 17 D pantothenylol, supplier: Hoffmann LaRoche
5 Neutrol TE, supplier: BASF 18 alpha-tocopherol acetates, supplier: BASF
6 200 proof, SDA 40-2 19 Cremophor RH 60, supplier: BASF
7 selenium sulfides, USP, supplier: Abbot Labs 20 Superol USP. suppliers: Procter ﹠amp;
Gamble
8 anti-dandruff active substances, 21 Sorbo, 70% sorbitol solution, supplier: ICI
9 benzene miaow butanols, supplier: Bayer AG 22 Lubrajel Oil, supplier: ISP
10 Unichem SALAC, supplier: UPI 23 Glucam E-20. supplier: Amerchol
11 anti-louse insecticide 24 Arlasolve 200L, supplier: ICI
12 handle enzymatic mixture 25 spice of louse, supplier: Haarman ﹠amp; Reimer
13 steroids-anti-the agent of itching, antiinflammatory
Claims (24)
1. packaged scalp cosmetic compositions, said composition contains:
A) leave scalp cosmetic compositions, said composition comprises the cleansing surfactants that is lower than 2% weight, and contains the following component in this leave scalp cosmetic compositions weight:
I) vapour pressure that the volatile liquid of 40% to 80% weight, this volatile liquid record 25 ℃ of temperature is greater than 23.7 millimetress of mercury,
Ii) 0.005% to 20% weight contain zinc anti-dandruff active substance and
The iii) liquid wetting agent of 0.1% to 20% weight,
Iv) the water of 5% to 50% weight and
The v) carbomer of 0.1% to 0.5% weight,
Wherein the viscosity of leave scalp cosmetic compositions is 1,000 to 20,000 centistoke, and
B) packing of this leave scalp cosmetic compositions is housed, wherein this packing has a plurality of openings, and this leave scalp cosmetic compositions is applied directly on the scalp by these openings.
2. the packaged scalp cosmetic compositions of claim 1, wherein containing zinc anti-dandruff content of active substance is 0.005% to 2% of leave scalp cosmetic compositions weight.
3. the packaged scalp cosmetic compositions of claim 2, wherein containing zinc anti-dandruff active substance is Zinc Pyrithione.
4. the packaged scalp cosmetic compositions of claim 1 wherein contains zinc anti-dandruff active substance and is selected from lactobionic acid zinc, Zinc Pyrithione, and combination.
5. the packaged scalp cosmetic compositions of claim 1, wherein volatile liquid is at least 25 millimetress of mercury in the vapour pressure that 25 ℃ of temperature record.
6. the packaged scalp cosmetic compositions of claim 5, wherein volatile liquid comprises the monohydric alcohol with 2 to 8 carbon atoms, and wherein monohydric alcohol accounts for 20% to 100% of this volatile liquid weight.
7. the packaged scalp cosmetic compositions of claim 6, wherein monohydric alcohol is an ethanol.
8. the packaged scalp cosmetic compositions of claim 1, wherein the content of liquid wetting agent is 1% to 5.0% of leave scalp cosmetic compositions weight.
9. the packaged scalp cosmetic compositions of claim 8, wherein the liquid wetting agent is selected from polypropylene glycol, Polyethylene Glycol, ethohexadiol, hexanediol, glycerol, propylene glycol, sorbitol, and combination.
10. the packaged scalp cosmetic compositions of claim 1, wherein the leave scalp cosmetic compositions further comprises the refrigerant sensory agent of 0.01% to 2% weight.
11. the packaged scalp cosmetic compositions of claim 1, wherein the leave scalp cosmetic compositions provides and has been at least 40% instantaneous scale minimizing value.
12. the packaged scalp cosmetic compositions of claim 1, wherein the leave scalp cosmetic compositions further contains vitamin E oil.
13. the packaged scalp cosmetic compositions of claim 1, wherein said liquid wetting agent provides at least 2.5 scalp humidification value for compositions.
14. the packaged scalp cosmetic compositions of claim 13, wherein the leave scalp cosmetic compositions provides 4.0 to 10.0 scalp humidification value.
15. the packaged scalp cosmetic compositions of claim 13, wherein the content of liquid wetting agent is 0.1% to 10% of leave scalp cosmetic compositions weight.
16. the packaged scalp cosmetic compositions of claim 13, wherein containing zinc anti-dandruff content of active substance is 0.005% to 2% of leave scalp cosmetic compositions weight.
17. the packaged scalp cosmetic compositions of claim 13, wherein containing zinc anti-dandruff active substance is Zinc Pyrithione.
18. the packaged scalp cosmetic compositions of claim 14, wherein this volatile liquid is at least 25 millimetress of mercury in the vapour pressure that 25 ℃ of temperature record, and comprise the monohydric alcohol with 2 to 8 carbon atoms, wherein the content of this monohydric alcohol is 20% to 100% of this volatile liquid weight.
19. the packaged scalp cosmetic compositions of claim 1, wherein said composition provides and has been at least 40% instantaneous scale minimizing value.
20. the packaged scalp cosmetic compositions of claim 19, wherein this leave scalp cosmetic compositions provides 4.0 to 10.0 scalp humidification value.
21. the packaged scalp cosmetic compositions of claim 19, wherein the content of liquid wetting agent is 0.1% to 10% of leave scalp cosmetic compositions weight.
22. the packaged scalp cosmetic compositions of claim 19, wherein containing zinc anti-dandruff content of active substance is 0.005% to 2% of leave scalp cosmetic compositions weight.
23. the packaged scalp cosmetic compositions of claim 22, wherein containing zinc anti-dandruff active substance is Zinc Pyrithione.
24. the packaged scalp cosmetic compositions of claim 19, wherein volatile liquid is at least 25 millimetress of mercury in the vapour pressure that 25 ℃ of temperature record, and comprise the monohydric alcohol with 2 to 8 carbon atoms, wherein the content of this monohydric alcohol is 20% to 100% of this volatile liquid weight.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68553600A | 2000-10-10 | 2000-10-10 | |
US09/685,536 | 2000-10-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1466447A CN1466447A (en) | 2004-01-07 |
CN1209093C true CN1209093C (en) | 2005-07-06 |
Family
ID=24752621
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 01816186 Expired - Fee Related CN1209093C (en) | 2000-10-10 | 2001-10-09 | Packaged scalp cosmetic compositions |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1324737A2 (en) |
JP (1) | JP2004511504A (en) |
CN (1) | CN1209093C (en) |
AU (1) | AU2002230397A1 (en) |
MX (1) | MXPA03003132A (en) |
WO (1) | WO2002032381A2 (en) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA01013447A (en) | 1999-06-25 | 2002-12-05 | Arch Chem Inc | Pyrithione biocides enhanced by silver, copper, or zinc ions. |
US7001594B1 (en) | 2000-10-10 | 2006-02-21 | The Procter & Gamble Company | Scalp cosmetic compositions and corresponding methods of application to provide scalp moisturization and skin active benefits |
WO2003059297A2 (en) * | 2002-01-21 | 2003-07-24 | Slovakofarma A.S. | Dermatological topical compositions and a process for the preparation thereof |
US9381148B2 (en) | 2003-03-18 | 2016-07-05 | The Procter & Gamble Company | Composition comprising particulate zinc material with a high relative zinc lability |
US9381382B2 (en) | 2002-06-04 | 2016-07-05 | The Procter & Gamble Company | Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a gel network |
BRPI0311568B1 (en) | 2002-07-05 | 2017-06-20 | Unilever N.V | Use of a topical composition and uses of an α-hydroxy acid |
US20040191331A1 (en) * | 2003-03-18 | 2004-09-30 | The Procter & Gamble Company | Composition comprising particulate zinc materials having a defined crystallite size |
DE102004012009A1 (en) * | 2004-03-10 | 2005-09-29 | Wella Ag | Antidandruff compositions, e.g. shampoos, containing synergistic active agent combination of acetylsalicylic acid, zinc pyrithione and piroctone olamine |
ATE551048T1 (en) * | 2004-06-28 | 2012-04-15 | Dsm Ip Assets Bv | COSMETIC COMPOSITIONS CONTAINING PROTEIN HYDROLYSATES |
FR2899794B1 (en) * | 2006-04-14 | 2011-03-04 | Jean Noel Thorel | HAIR COSMETIC COMPOSITION |
JP5033381B2 (en) * | 2006-09-14 | 2012-09-26 | 株式会社池田模範堂 | Pharmaceutical composition for external use |
DE102006047163A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine methyl ester and an antioxidant |
DE102006047160A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine methyl ester and a filler |
DE102006047154A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine ethyl ester and an antiinflammatory agent |
DE102006047166A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine ethyl ester and a skin moisturizer |
DE102006047153A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine methyl ester and an antiinflammatory agent |
DE102006047155A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine ethyl ester and an antioxidant |
DE102006047159A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine ethyl ester and a filler |
DE102006047164A1 (en) * | 2006-09-29 | 2008-04-03 | Beiersdorf Ag | Cosmetic or dermatological composition comprises 2-isopropyl-5-methylcyclohexylcarbonyl-D-alanine methyl ester and a skin moisturizer |
WO2011045840A1 (en) * | 2009-10-15 | 2011-04-21 | 株式会社アスター美容 | Hair cosmetic composition |
JP5460766B2 (en) * | 2012-03-15 | 2014-04-02 | 株式会社池田模範堂 | Pharmaceutical composition for external use |
JP6157185B2 (en) * | 2013-04-05 | 2017-07-05 | ポーラ化成工業株式会社 | Skin external preparation with cooling sensation |
TW201440800A (en) * | 2013-04-19 | 2014-11-01 | Chi-Wu Hsu | Composition for the treatment of dandruff |
MX2016002482A (en) * | 2013-09-05 | 2016-05-31 | Procter & Gamble | Scalp care composition. |
CN106232099B (en) * | 2014-04-24 | 2022-04-12 | 宝洁公司 | Scalp care compositions |
US20170165158A1 (en) * | 2014-06-24 | 2017-06-15 | Conopco, Inc., D/B/A Unilever | Hair treatment composition |
JP6708377B2 (en) * | 2015-07-22 | 2020-06-10 | アース製薬株式会社 | Lice repellent |
CN105213251B (en) * | 2015-09-22 | 2017-11-07 | 拉芳家化股份有限公司 | A kind of anticreep shampoo with thermal sensation |
GB2562270B (en) * | 2017-05-10 | 2020-07-01 | Hyphens Pharma Pte Ltd | Skin barrier composition |
CN109431914B (en) * | 2018-12-27 | 2020-07-07 | 湖南御家化妆品制造有限公司 | Scalp care composition and application thereof |
US11141309B2 (en) | 2019-06-03 | 2021-10-12 | Cooler Heads Care, Inc. | Cooling cap assembly and cooling unit |
CN110169929A (en) * | 2019-06-20 | 2019-08-27 | 上海绿瑞生物科技有限公司 | A kind of scalp care Essence, preparation method and its application method |
JP7257354B2 (en) * | 2020-04-02 | 2023-04-13 | アース製薬株式会社 | How to avoid lice |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4728667A (en) * | 1984-12-21 | 1988-03-01 | Shiseido Company Ltd. | Hair treatment composition for prevention of dandruff in hair |
FR2592004B1 (en) * | 1985-12-24 | 1988-09-02 | Oreal | PRESSURIZED CONTAINER FOR DELIVERING IMPROVED QUALITY FOAM IN A CONTROLLED WAY |
GB2235380A (en) * | 1989-08-29 | 1991-03-06 | Oswald Morton | Anti-dandruff composition |
JPH03141213A (en) * | 1989-10-26 | 1991-06-17 | Seiko Corp | Hair tonic |
DE69819486T2 (en) * | 1997-05-13 | 2004-09-16 | The Procter & Gamble Company, Cincinnati | PACKED ANTI-SWEATING CREAM COMPOSITION |
US20020035070A1 (en) * | 2000-07-26 | 2002-03-21 | The Procter & Gamble Company | Method of regulating hair growth using metal complexes of oxidized carbohydrates |
-
2001
- 2001-10-09 AU AU2002230397A patent/AU2002230397A1/en not_active Abandoned
- 2001-10-09 EP EP01987657A patent/EP1324737A2/en not_active Ceased
- 2001-10-09 MX MXPA03003132A patent/MXPA03003132A/en not_active Application Discontinuation
- 2001-10-09 WO PCT/US2001/042580 patent/WO2002032381A2/en not_active Application Discontinuation
- 2001-10-09 CN CN 01816186 patent/CN1209093C/en not_active Expired - Fee Related
- 2001-10-09 JP JP2002535620A patent/JP2004511504A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2004511504A (en) | 2004-04-15 |
EP1324737A2 (en) | 2003-07-09 |
AU2002230397A1 (en) | 2002-04-29 |
MXPA03003132A (en) | 2003-07-14 |
WO2002032381A2 (en) | 2002-04-25 |
WO2002032381A3 (en) | 2003-01-03 |
CN1466447A (en) | 2004-01-07 |
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