CN1207421A - Method for spinning bio-absorption stanch fibre - Google Patents
Method for spinning bio-absorption stanch fibre Download PDFInfo
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- CN1207421A CN1207421A CN 98115843 CN98115843A CN1207421A CN 1207421 A CN1207421 A CN 1207421A CN 98115843 CN98115843 CN 98115843 CN 98115843 A CN98115843 A CN 98115843A CN 1207421 A CN1207421 A CN 1207421A
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- spinning
- stanch fibre
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- bulk absorption
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Abstract
A method for spinning stanch fibre able to be absorbed by living body features that the staltic medicine is dissolved in to main material such as animal protein and polyvinyl alcohol to prepare spinning solution, which is then spun into superfine stanch fibre by air jet spinning technology. Its advantages are simple process, stable quality and no environmental pollution. Obtained stanch fibre used in medical operation and for wound features quick staltic effect, no untoward effect, and being absorbed by tissue in body.
Description
The invention belongs to functional high molecule material processing method field, what be specifically related to is a kind of spinning process of giving birth to the bulk absorption stanch fibre.
Hemorrhage is one of symptom common in wartime and the daily life, though the domestic and international clinical multiple hemostatic of using, but medicine source, the property of medicine, formulation, hemostatic healing efficacy, toxic and side effect and degree of absorption all have certain limitation, according to hemostatic mechanism with to the screening of a large amount of haemostatic medicaments, formulation, be recognized that in the different dosage form of same haemostatic medicament with fibrous to be haemostatic effect the best of dressing.So, people for many years, be devoted to the research and development of stanch fibre aspect always, external stanch fibre lays particular emphasis on calcium alginate and cellulose modified, China then lays particular emphasis on the use of gelatin materials, and having developed in succession with gelatin and polyvinyl alcohol is that main body is carried out wet spinning and dry spinning is produced stanch fibre.But shortcoming such as two kinds of methods have, and process equipment is more, production process is grown, yield poorly, the energy and supplies consumption are big.
Purpose of the present invention is intended to explore a kind of easy, spinning technique that the medical hemostatic superfine fibre is produced in one-shot forming.
The object of the present invention is achieved like this: haemostatic medicament is dissolved in be mixed with the solution-type spinning solution in the material of main part, adopt the used gas blowout spinning technique of fusion material again, one-step shaping forms.
The present invention specifically comprises the technical process of following order: (1) becomes spinning solution to be added to the water swelling, stirring and dissolving of material of main part and haemostatic medicament by proportioning; (2) spinning solution is glued accent; Then, (3) deaeration; (4) the solution thread is sprayed in spinning nozzle; (5),, be scattered on the stainless (steel) wire through hot-air dehydration coagulation forming by the path; (6) after fumigation, be wound on the finished product axle or be scattered in the fiber groove bucket.
The component of above-mentioned spinning solution is mainly (by weight percentage): polyvinyl alcohol 0-45%, animal protein 0-45%, berberine hydrochloride 0.1-5%, sweetgum leaf extract 0.1-5%, soft water 50-75%.The best proportioning of each component is (by weight percentage): polyvinyl alcohol 23%, animal protein 23%, berberine hydrochloride 0.2%, sweetgum leaf extract 0.2%, soft water 53.6%.The value of above-mentioned each component is determined by fiber spinnability and anthemorrhagic speed.In the said components, polyvinyl alcohol and animal protein are material of main part, and berberine hydrochloride and sweetgum leaf extract are haemostatic medicament.
The concentration of dope that contains haemostatic medicament is between the 25-50%, makes the solution thread of the ejection coagulation forming that dewaters in hot-air easily.Contain balance moisture content 10% in fiber, the moisture content amount that should slough in spinning moulding is 100%-(50-25%+10%)=65-40%.
The gas blowout method is by means of the thickness and the length of the high velocity air control staple fibre of spinning nozzle slit ejection, and after gas speed and binder amount were determined, the thickness of fiber determined thereupon that also its length is change at random in a scope then.
The using method of the stanch fibre that the present invention produces is: stanch fibre spread on the shallow table surface of a wound, depth groups weaves the blood surface of a wound or the hemorrhage surface of a wound of cranial surgery, also can be filled in bleeding parts such as nasal cavity, hemorrhoid complicated by anal fistula, oral cavity, vagina, pushing several branch kinds can stop blooding, in general, for little wound, only need just can stop in one minute and bleeding.It is widely used in the hemostasis of wounds such as Orthopeadic Surgery, gynemetrics, urological department, ENT dept., Oncological Surgery and surgical wound surface, and is especially more effective to the hemostasis of parenchymal visceras such as liver,spleen,kidney, cavity and the deep tissue surface of a wound.
Technique effect of the present invention is: it is pattern that the present invention intends with the melt blown technology, adopts solution to carry out spinning, from the production angle, has improved production efficiency greatly, reduces many operations, thereby has reduced the energy consumption of fiber, has reduced production cost; From medical angle, former medicine is dissolved in the stoste in advance, can save the operation of soaking medicine again after the spinning like this, there is not the artificial pollution possibility, in addition, because production process shortens, reduced the contaminated chance of fiber, overcome by many shortcomings of bringing on the technology, adapted to the production needs and the medical needs of stanch fibre more.With the living bulk absorption stanch fibre that the present invention makes, thin its topped area that is interweaved is big and soft, and is good with surface of a wound adhesion, and hemostasis rapidly, and wound is protected in anti-inflammatory, and is safe and reliable, easy to use, particularly can be given birth to the characteristics that soma absorbs, make it more be subjected to patient and medical personnel's welcome.
The invention will be further described below in conjunction with drawings and Examples.
Fig. 1 is the process chart of the embodiment of the invention.
According to configuration device shown in Figure 1.Numbering among Fig. 1 is as follows: 1-dissolution kettle, 2-gear pump, 3-filter, 4-dissolution kettle, 5-gear pump, 6-filter, the 7-deaerator, 8-nitrogen, the 9-spinning nozzle, 10-hot-air, 11-are pressed empty heater, the 12-dehumidification is pressed pocket, 13-path, 14-stainless (steel) wire, 15-hydroformylation device, 16-finished product axle.
Embodiment one:
In the stainless steel dissolution kettle 1 of agitator is housed, add 832.60g polyvinyl alcohol and 970.16g soft water, made the polyvinyl alcohol swelling 30 minutes, be warming up to 85 ℃ and begin to stir, dissolved 90 minutes.Sweetgum leaf extract 7.24g, berberine hydrochloride 7.24g and 970.16g soft water are joined in the stainless steel dissolution kettle 4, heat up 60 ℃ and mix, add the 832.60g gelatin then, at room temperature left standstill swelling 30 minutes, then the mixed liquor in the dissolution kettle 1 is driven in the dissolution kettle 4 through gear pump 2 filters 3,70 ℃ of following stirring and dissolving after 60 minutes, sticking to transfer to viscosity be the 8000-10000 centipoise, again through entering in the deaerator 7 standing and defoaming behind gear pump 5, the filter 6 120 minutes.
Blend solution through deaeration is that spinning solution is keeping under 70 ℃ of situations of temperature, under the pressure of 0.2MPa, the solution thread is sprayed in spinning nozzle 9, by path 13, through hot-air 10 dehydration coagulation formings, be scattered on the stainless (steel) wire 14, in hydroformylation device 15, fumigate again with formaldehyde steam, make fiber reach certain mechanical strength, be wound on again on the finished product axle 16.And then according to market and user's needs, pack, the ethane via epoxyethane gas depoisoning is deposited after ten days and can be used again.
For making fiber be scattered in mutual adhesion on the stainless steel cloth 14, must make its path long enough that in hot-air, falls, path 13 is about and is 2-4M.Present embodiment adopts between the far infrared high temperature, short time and dewaters, and makes the certain thermal crystalline of intermolecular generation of orientation.Embodiment two:
In the stainless steel dissolution kettle 1 of agitator is housed, add 300.00g soft water, heat up 60 ℃, add 10.00g sweetgum leaf extract then and the 10.00g berberine hydrochloride mixes, dissolved 90 minutes.1629.00g polyvinyl alcohol and 1671.00g soft water are joined in the stainless steel dissolution kettle 4, swelling 30 minutes, being warming up to 85 ℃ begins to stir, dissolved 90 minutes, again the soup after the dissolving in the stainless steel dissolution kettle 1 is driven into behind gear pump 2 filters 3 in the poly-vinyl alcohol solution of dissolving in the dissolution kettle 4,70 ℃ of following stirring and dissolving after 60 minutes, sticking to transfer to viscosity be the 8000-10000 centipoise, entered in the deaerator 7 standing and defoaming 120 minutes through gear pump 5, filter 6 again.
All the other processes are as described in the embodiment 1.Embodiment three:
In the stainless steel dissolution kettle 1 of agitator is housed, add 300.00g soft water, heat up 60 ℃, add 10.00g sweetgum leaf extract then and the 10.00g berberine hydrochloride mixes, dissolved 90 minutes.1629.00g gelatin and 1671.00g soft water are joined in the stainless steel dissolution kettle 4, swelling 30 minutes, being warming up to 85 ℃ begins to stir, dissolved 90 minutes, again being driven into behind soup gear pump 2 filters 3 after the dissolving in the stainless steel dissolution kettle 1 in the gelatin solution of dissolving in the dissolution kettle 4,70 ℃ of following stirring and dissolving after 60 minutes, sticking to transfer to viscosity be the 8000-10000 centipoise, entered in the deaerator 7 standing and defoaming 120 minutes through gear pump 5, filter 6 again.
All the other processes are as described in the example 1.
Each component of spinning solution all derives from the commercially available prod among above-mentioned three embodiment.
Claims (5)
1. spinning process of giving birth to the bulk absorption stanch fibre is characterized in that: haemostatic medicament is dissolved in be mixed with the solution-type spinning solution in the material of main part, adopt the used gas blowout spinning technique of fusion material again, one-step shaping is spun into stanch fibre.
2. the spinning process of living bulk absorption stanch fibre according to claim 1 is characterized in that: specifically comprise the technical process of following order, (1) becomes spinning solution to be added to the water swelling, stirring and dissolving of material of main part and haemostatic medicament by proportioning; (2) spinning solution is glued accent; Then, (3) deaeration; (4) the solution thread is sprayed in spinning nozzle; (5),, be scattered on the stainless (steel) wire through hot-air dehydration coagulation forming by the path; (6) after fumigation, be wound on the finished product axle or be scattered in the fiber groove bucket.
3. the spinning process of living bulk absorption stanch fibre according to claim 1 and 2 is characterized in that: the component of described spinning solution is mainly (by weight percentage),
Polyvinyl alcohol 0-45%,
Animal protein 0-45%,
Berberine hydrochloride 0.1-5%,
Sweetgum leaf extract 0.1-5%,
Soft water 50-75%.
4. the spinning process of living bulk absorption stanch fibre according to claim 3 is characterized in that: the best proportioning of described each component of spinning solution is (by weight percentage),
Polyvinyl alcohol 23%,
Animal protein 23%,
Berberine hydrochloride 0.2%,
Sweetgum leaf extract 0.2%,
Soft water 53.6%.
5. the spinning process of living bulk absorption stanch fibre according to claim 3 is characterized in that: described animal protein is selected gelatin for use.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98115843 CN1207421A (en) | 1998-07-16 | 1998-07-16 | Method for spinning bio-absorption stanch fibre |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 98115843 CN1207421A (en) | 1998-07-16 | 1998-07-16 | Method for spinning bio-absorption stanch fibre |
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| Publication Number | Publication Date |
|---|---|
| CN1207421A true CN1207421A (en) | 1999-02-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 98115843 Pending CN1207421A (en) | 1998-07-16 | 1998-07-16 | Method for spinning bio-absorption stanch fibre |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1314844C (en) * | 2004-07-08 | 2007-05-09 | 武汉科技学院 | Fiber modified by Chinese traditional medicine and manufacturing method thereof |
| CN100462487C (en) * | 2005-02-05 | 2009-02-18 | 李官奇 | Protein fiber spinning dope and its preparing method |
| CN1814869B (en) * | 2005-02-05 | 2010-04-28 | 李官奇 | Protein fiber spinning dope capable of absorbing wave, shielding and absorbing heat, and its preparing method |
| CN104888267A (en) * | 2015-05-25 | 2015-09-09 | 浙江华峰氨纶股份有限公司 | Medicinal bleeding-stopping spandex fiber fabric and preparation method thereof |
| CN105886966A (en) * | 2016-06-06 | 2016-08-24 | 天津大学 | Zirconium-based multi-component amorphous alloy with high thermal stability and preparation method thereof |
-
1998
- 1998-07-16 CN CN 98115843 patent/CN1207421A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1314844C (en) * | 2004-07-08 | 2007-05-09 | 武汉科技学院 | Fiber modified by Chinese traditional medicine and manufacturing method thereof |
| CN100462487C (en) * | 2005-02-05 | 2009-02-18 | 李官奇 | Protein fiber spinning dope and its preparing method |
| CN1814869B (en) * | 2005-02-05 | 2010-04-28 | 李官奇 | Protein fiber spinning dope capable of absorbing wave, shielding and absorbing heat, and its preparing method |
| CN104888267A (en) * | 2015-05-25 | 2015-09-09 | 浙江华峰氨纶股份有限公司 | Medicinal bleeding-stopping spandex fiber fabric and preparation method thereof |
| CN105886966A (en) * | 2016-06-06 | 2016-08-24 | 天津大学 | Zirconium-based multi-component amorphous alloy with high thermal stability and preparation method thereof |
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