CN1192365A - Traditional Chinese medicine for treating mastosis - Google Patents
Traditional Chinese medicine for treating mastosis Download PDFInfo
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- CN1192365A CN1192365A CN98100875A CN98100875A CN1192365A CN 1192365 A CN1192365 A CN 1192365A CN 98100875 A CN98100875 A CN 98100875A CN 98100875 A CN98100875 A CN 98100875A CN 1192365 A CN1192365 A CN 1192365A
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Abstract
A traditional Chinese prescription medicine for treating mammary gland diseases is composed of Radix Bupleuri, Radix Scutellariae, Radix Codonopsis Pilosulae, Radix Glycyrrhizae, Spica Prunellae, Semen Vaccariae, Concha Ostreae, date, Fructus Trichosanthis, gypsum, Pericarpium Citri Reticulatae, Radix Paeoniae Alba, etc. The invented medicine possesses good curing effect against mammary gland proliferation, mommary gland fibroma and breast cancer.
Description
The present invention is a kind of Chinese medicine for the treatment of mastopathy, is the Chinese patent medicine that is used for the treatment of diseases such as cyclomastopathy, mammary gland fibroma and breast carcinoma specifically, belongs to drug world.
Breast disease is a kind of adult women's of betiding a commonly encountered diseases, mainly show as cyclomastopathy, mammary gland fibroma and breast carcinoma, these three kinds of diseases have certain dependency in the middle of the process that development takes place, therefore, prevent and treat cyclomastopathy energetically, further evolution that can disease preventing and treating.Though at present more for the medicine kind of cyclomastopathy, these drug effects are single, for the comparatively serious disease of some hypertrophy, the multiple cystic hyperplasia of moderate lobules of mammary gland and mammary gland for example, the said medicine treatment all can not obtain curative effect preferably.Treatment for mammary gland fibroma generally is a Therapeutic Method of taking excision at present, is not treated surgically but most of patients is glad, after the corrective surgery excision that particularly has, recurrence occurs, faces the misery of operation once more.And, still do not see effective medicine in the middle of the Chinese patent medicine at present for the treatment of breast carcinoma.Therefore, develop a kind of active drug for the treatment of above-mentioned mastopathy, be pressing for of present clinical treatment practice, and be the useful contribution of bringing benefit to the mankind.
The object of the invention provides a kind of Chinese patent medicine of effective treatment mastopathy, particularly cyclomastopathy, mammary gland fibroma and breast carcinoma is had the Chinese medicine of better therapeutic effect.
Medicine of the present invention is to be the pharmaceutical preparation that active constituent is prepared from following Chinese medicine pharmaceutical composition:
Radix Bupleuri 20-40 part
Radix Scutellariae 20-40 part
Fructus Perillae 50-70 part
Radix Codonopsis 50-70 part
Radix Glycyrrhizae 8-15 part
Spica Prunellae 50-70 part
Semen Vaccariae 150-200 part
Concha Ostreae 50-70 part
Fructus Jujubae 10-30 part
Fructus Trichosanthis 50-70 part
Gypsum Fibrosum 50-70 part
Pericarpium Citri Reticulatae 50-70 part
Radix Paeoniae Alba 50-70 part
Fructus Zanthoxyli 8-15 part
The proportioning of aforementioned pharmaceutical compositions is a weight portion, and its best proportioning is:
30 parts of Radix Bupleuri
30 parts of Radix Scutellariaes
60 parts of Fructus Perillaes
60 parts of Radix Codonopsis
12 parts in Radix Glycyrrhizae
60 parts of Spica Prunellaes
180 parts of Semen Vaccariae
60 parts of Concha Ostreaes
20 parts in Fructus Jujubae
60 parts of Fructus Trichosanthis
60 parts in Gypsum Fibrosum
60 parts of Pericarpium Citri Reticulataes
60 parts of the Radix Paeoniae Albas
10 parts of Fructus Zanthoxylis
Aforementioned pharmaceutical compositions of the present invention is that the monarch principles of formulating prescriptions compatibility according to the traditional Chinese medical science forms, and according to the pharmaceutical technology of routine, aforementioned pharmaceutical compositions can be prepared into any pharmaceutical dosage form that is suitable for using clinically.For example, capsule, tablet, pill, oral liquid, powder, external use plaster etc.
The method that aforementioned pharmaceutical compositions is prepared into capsule is:
Choose medical material according to described consumption proportion, oven dry is pulverized, and sieves, and makes fine powder, and is encapsulated, promptly.
Pharmaceutical preparation of the present invention is used for clinical practice, obtained notable therapeutic effect, facts have proved that pharmaceutical preparation of the present invention has reliable curative effect for cyclomastopathy, mammary gland fibroma and breast carcinoma, the outstanding effect that has further confirmed medicine of the present invention is summed up in following clinical practice.
Experimental example Drug therapy breast disease 306 routine clinical summaries one of the present invention, data and method
1,306 routine mammary gland patients comprise that various cyclomastopathy, mammary gland fibroma and patient with breast cancer are the outpatient service prescription on individual diagnosis patient of breast disease section of the sub-hospital of Chaoyang District, Beijing City water-powered trip-hammer.
2, diagnostic method:, adopt cold high light transilluminator transillumination method to check and make a definite diagnosis in conjunction with palpation, inquiring.Two, 306 routine breast disease situation analysis
1, the age: minimal ages 17 years old, maximum 60 years old age, 38.5 years old mean age.
2, sex: 306 examples all are the women, and promptly falling ill accounts for absolute majority with the women.
3, the sick kind: cyclomastopathy 108 examples account for 35.29% of sum; Mammary gland fibroma 185 examples account for 60.46% of sum; Mammary cancer 13 examples account for 4.25% of sum.Three, Therapeutic Method: oral decoction or the capsule administration of adopting pharmaceutical composition of the present invention to make, mammary gland fibroma and various cyclomastopathy are a course of treatment to take medicine one month, and it is a course of treatment that breast carcinoma was taken medicine 4 months.Four, efficacy assessment standard
Focus is reduced into effectively after the medication;
Focus obviously is reduced into produce effects after the medication;
Foci disappearance is for curing after the medication;
The focus no change is invalid after the medication.Five, result
1,108 routine cyclomastopathy patients take medicine and all cure cure rate 100% 1-3 the course of treatment;
2, the 185 routine mammary gland fibroma 1-3 of hospital course of treatment, 162 examples are cured, and cure rate 87.5%, 23 example is a produce effects;
3,13 routine breast carcinoma medication treatment back lumps all obviously dwindle even disappear, and effective percentage is 100%.
The traditional Chinese medical science is divided into acute mastitis, nodules of the breast, breast carcinoma with mastopathy by disease, i.e. the cyclomastopathy of modern medicine, mammary gland fibroma and breast carcinoma.Mostly be depression of liver-QI by its pathogenesis of theory of Chinese medical science, excessiveness of stomach-heat, qi depression to blood stasis, the poly-poison of the newborn stasis of blood forms slight illness.Its disease is that breast QI and blood and blockage of main and collateral channels form.The internal treatment is adopted in treatment, is the Therapeutic Principle with depressed liver-energy dispersing and QI regulating, disperse blood stasis and dredge collateral.Pharmaceutical composition of the present invention is a monarch drug with Radix Bupleuri, Semen Vaccariae, with the Radix Paeoniae Alba, Fructus Trichosanthis, Spica Prunellae is ministerial drug, is adjuvant drug with Pericarpium Citri Reticulatae, Radix Scutellariae, Gypsum Fibrosum, Radix Codonopsis, Fructus Jujubae, Fructus Zanthoxyli, Radix Glycyrrhizae, is messenger drug with Fructus Perillae and Semen Vaccariae, form prescription, realized therapeutic purposes of the present invention.
Embodiment 1
Radix Bupleuri 30 grams
Radix Scutellariae 30 grams
Fructus Perillae 60 grams
Radix Codonopsis 60 grams
Radix Glycyrrhizae 12 grams
Spica Prunellae 60 grams
Semen Vaccariae 180 grams
Concha Ostreae 60 grams
Fructus Jujubae 20 grams
Fructus Trichosanthis 60 grams
Gypsum Fibrosum 60 grams
Pericarpium Citri Reticulatae 60 grams
The Radix Paeoniae Alba 60 grams
Fructus Zanthoxyli 10 grams
With above-mentioned medical material, oven dry is ground into fine powder, crosses 100 mesh sieves, and is encapsulated, and every capsules contains medicated powder 1 gram.
Embodiment 2
Radix Bupleuri 40 grams
Radix Scutellariae 20 grams
Fructus Perillae 50 grams
Radix Codonopsis 70 grams
Radix Glycyrrhizae 8 grams
Spica Prunellae 50 grams
Semen Vaccariae 200 grams
Concha Ostreae 70 grams
Fructus Jujubae 15 grams
Fructus Trichosanthis 50 grams
Gypsum Fibrosum 60 grams
Pericarpium Citri Reticulatae 50 grams
The Radix Paeoniae Alba 50 grams
Fructus Zanthoxyli 15 grams
Said medicine is decocted with water twice, for the first time add 3 times of water gagings, decocted 1 hour, add 2 times of amounts of water for the second time, decocted 0.5 hour, merge decocting liquid twice, filtration, canned when being concentrated into 1 times with respect to the crude drug amount, 10 milliliters every, sterilize, make oral liquid.
Claims (3)
1, a kind of pharmaceutical composition for the treatment of mastopathy is characterized in that forming and counts by weight:
Radix Bupleuri 20-40 part
Radix Scutellariae 20-40 part
Fructus Perillae 50-70 part
Radix Codonopsis 50-70 part
Radix Glycyrrhizae 8-15 part
Spica Prunellae 50-70 part
Semen Vaccariae 150-200 part
Concha Ostreae 50-70 part
Fructus Jujubae 10-30 part
Fructus Trichosanthis 50-70 part
Gypsum Fibrosum 50-70 part
Pericarpium Citri Reticulatae 50-70 part
Radix Paeoniae Alba 50-70 part
Fructus Zanthoxyli 8-15 part
2,, it is characterized in that the ratio of each component is according to the pharmaceutical composition of claim 1:
30 parts of Radix Bupleuri
30 parts of Radix Scutellariaes
60 parts of Fructus Perillaes
60 parts of Radix Codonopsis
12 parts in Radix Glycyrrhizae
60 parts of Spica Prunellaes
180 parts of Semen Vaccariae
60 parts of Concha Ostreaes
20 parts in Fructus Jujubae
60 parts of Fructus Trichosanthis
60 parts in Gypsum Fibrosum
60 parts of Pericarpium Citri Reticulataes
60 parts of the Radix Paeoniae Albas
10 parts of Fructus Zanthoxylis
3, according to the pharmaceutical composition of claim 1, the dosage form that it is characterized in that this medicine is a capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98100875A CN1054541C (en) | 1998-03-02 | 1998-03-02 | Traditional Chinese medicine for treating mastosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN98100875A CN1054541C (en) | 1998-03-02 | 1998-03-02 | Traditional Chinese medicine for treating mastosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1192365A true CN1192365A (en) | 1998-09-09 |
| CN1054541C CN1054541C (en) | 2000-07-19 |
Family
ID=5216309
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN98100875A Expired - Fee Related CN1054541C (en) | 1998-03-02 | 1998-03-02 | Traditional Chinese medicine for treating mastosis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1054541C (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101485862B (en) * | 2009-02-27 | 2011-08-31 | 程裕厚 | Chinese medicament preparation for treating mastopathy |
| CN101675961B (en) * | 2008-09-18 | 2012-09-12 | 上海中医药大学附属曙光医院 | A medicinal preparation for treating breast cancer and preparation method thereof |
| CN103768563A (en) * | 2013-12-30 | 2014-05-07 | 刘玉含 | Fibroma nursing medicine and preparation method thereof |
| CN112220819A (en) * | 2020-11-23 | 2021-01-15 | 南方医科大学南方医院 | Traditional Chinese medicine composition and preparation method and application thereof |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101143162B (en) * | 2007-09-03 | 2010-09-01 | 马海龙 | Medicinal liquor for treating mastoproliferation and its preparing process |
-
1998
- 1998-03-02 CN CN98100875A patent/CN1054541C/en not_active Expired - Fee Related
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101675961B (en) * | 2008-09-18 | 2012-09-12 | 上海中医药大学附属曙光医院 | A medicinal preparation for treating breast cancer and preparation method thereof |
| CN101485862B (en) * | 2009-02-27 | 2011-08-31 | 程裕厚 | Chinese medicament preparation for treating mastopathy |
| CN103768563A (en) * | 2013-12-30 | 2014-05-07 | 刘玉含 | Fibroma nursing medicine and preparation method thereof |
| CN112220819A (en) * | 2020-11-23 | 2021-01-15 | 南方医科大学南方医院 | Traditional Chinese medicine composition and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1054541C (en) | 2000-07-19 |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C53 | Correction of patent for invention or patent application | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: PATENTEE; FROM: ZHENG YINFENG TO: WANG ZHIHUA |
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| CP03 | Change of name, title or address |
Address after: 100018, 5-2-101, sixteen Bureau of East Gate, Beijing, Chaoyang District Patentee after: Wang Zhihua Address before: 100061 Beijing city Chongwen District fahuasi area 26 Building 1 unit 201 Patentee before: Zheng Yinfeng |
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| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |