CN1191138A - Process for preparing prescription and medicinal extract of plaster for activating meridians - Google Patents

Process for preparing prescription and medicinal extract of plaster for activating meridians Download PDF

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Publication number
CN1191138A
CN1191138A CN98113478A CN98113478A CN1191138A CN 1191138 A CN1191138 A CN 1191138A CN 98113478 A CN98113478 A CN 98113478A CN 98113478 A CN98113478 A CN 98113478A CN 1191138 A CN1191138 A CN 1191138A
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radix
blood
radix angelicae
rhizoma
plaster
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CN1060394C (en
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扈盛
扈克文
张朝润
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Abstract

A new prescription of Huoluo plaster for treating later sports injury, chronic muscle strain, rheumatism and old injury with unique curative effect is prepared from 14 Chinese-medicinal materials such as Dragon's blood, Chinese angelica root, Chuan-xiong rhizome, safflower, frankincense, etc. through thoroughly mixing, alcohol leaching, concentration to obtain extract, preparing matrix with rubber and rosin, spreading with extract, cutting and covering.

Description

The preparation method of new blood circulation activating plaster prescription and unguentum
The present invention relates to a kind of Chinese medicine preparation for the treatment of athletic injury, particularly outmoded injury and preparation method thereof.
The traditional theory and the experience of Chinese medicine and pharmacy are thought: different forms of violence, and to frustrate as traumatic injury and to turn round, bump weight equivalent damage all can cause the skin and flesh bones and muscles injury, and qi and blood stagnation causes pain, swelling and dysfunction.If treat untimely or do not know the right way, delay with the passing of time, the unsmooth benefit of QI and blood very then more can cause the local organization adhesion, stiff or muscles contracture, limitation of activity etc.Chronic strain and Liver and kidney weakness again, also can cause the joint arrest twin, flesh muscle pain or move weak etc.Because blood fortune in these injuries is unsmooth, is easily invaded by wind-cold damp pathogen, become and hinder the stasis of blood and hold numbness under the arm, meridians lose in the warm outmoded injury that causes, and recovery is got up just more difficult.
Traditional view is thought: athletic injury mostly is the case of a physically strong patient running a high fever.Many double wind-cold damp pathogens of holding under the arm show as local arthralgia pain and are weighing, joint stuffiness, and numbness of the skin, overcast and rainy then sx or have muscular atrophy soft, except that suitable active eliminating stasis to stop pain, the medicine that need be aided with expelling wind and cold especially simultaneously can remove sick.
Develop a kind of blood circulation activating plaster based on above-mentioned theory professor Zheng Huaixian, by Moschus, Rhizoma Chuanxiong, Rhizoma Kaempferiae, Myrrha, Cortex Cinnamomi, the Radix Angelicae Dahuricae, Lignum Santali Albi, Radix Dipsaci, Radix Angelicae Sinensis, Rhizoma Et Radix Notopterygii, Sanguis Draxonis, Flos Carthami, Herba lysimachiae capillipedis, Radix Angelicae Pubescentis, Radix Aristolochiae, Flos Caryophylli preparation.This agent is a principal agent with Moschus, Rhizoma Chuanxiong, focuses on blood circulation promoting and blood stasis dispelling, warming the meridian eliminating impediment, reducing swelling and alleviating pain.Moschus resource in the medicament is very deficient, and valency is high rare.Adopt Rhizoma Kaempferiae, though the merit of reducing swelling and alleviating pain is arranged, deficiency of YIN anemia person avoids usefulness, and in the athletic injury later stage, qi-blood deficiency syndrome appears in local organization, and the blood circulation promoting medicine in the prescription has the merit of removing blood stasis, can consume gas, cause QI and blood deficiency by removing blood stasis.The utilization Rhizoma Kaempferiae more can consume impairment of QI blood, increase the weight of deficient syndrome, causes the local organization indolence.Sanguis Draxonis is an auxiliary medicine in the plaster, only accounts for dose 2.9%.
The preparation method of this unguentum is, above-mentioned medical herbs is ground into the powder mixing, and Plumbum preparatium, Oleum Verniciae fordii are boiled into substrate, by the time add medicated powder behind the suitable temperature, mix homogeneously is coated with cream and gets final product by rule of thumb.Adopt this technology to have following problem:
1, add the bad grasp of temperature of medicated powder, the temperature height, the active drug composition of armaticity medical materials such as Moschus, Lignum Santali Albi is volatile, and the low then medicated powder of temperature can add, and mixed inhomogeneous,
2, Plumbum preparatium, produce dense oil smoke of black and stink when Oleum Verniciae fordii is tempered, and poisonous, contaminated environment influences health of operators;
3, contain medicinal residues in the plaster, active constituent content is low in the medicine, and dosage is big, and plaster thickness has 5mm, need heat when putting up and stick the back hardening, influences joint motion, makes the athlete can't carry out proper motion, and the time of pasting is long, needs one week of subsides effective with the top.
The objective of the invention is principle in line with " control wind control blood, blood earlier control wind " from going out, a kind of blood activating and promoting tissue regeneration that has is provided, nourish blood enrich blood, warming the meridian eliminating impediment, active dissipating blood stasis, expelling wind and cold, the gas compensation function of invigorating blood circulation can be treated new blood circulation activating plaster preparation of athletic injury, particularly outmoded injury and preparation method thereof.
The implementation of the object of the invention is, new blood circulation activating plaster prescription by
Sanguis Draxonis 2.0-10.0g Radix Angelicae Sinensis 2.1-7.0g
Rhizoma Chuanxiong 6.2-10.0g Flos Carthami 2.1-1.0g
Olibanum 6.2-10.0g Radix Dipsaci 6.2-10.0
Rhizoma Et Radix Notopterygii 6.2-10.0g Radix Angelicae Pubescentis 6.2-10.0g
Radix Angelicae Dahuricae 6.2-10 0g Herba lysimachiae capillipedis 2.1-7.0g
Flos Caryophylli 2.1-7.1g Lignum Santali Albi 2.1-7.0g
6.2-10.0g is formulated for Cortex Cinnamomi 2.1-7.0g Radix Aristolochiae.
New blood circulation activating plaster preparation method, get Sanguis Draxonis 2-10g, Radix Angelicae Sinensis 2.1-7.0g, Rhizoma Chuanxiong 6.2-10.0g, Flos Carthami 2.1-7.0g, Olibanum 6.2-10.0g, Radix Dipsaci 6.2-10.0, Rhizoma Et Radix Notopterygii 6.2-10.0g, Radix Angelicae Pubescentis 6.2-10.0g, Radix Angelicae Dahuricae 6.2-10.0g, Herba lysimachiae capillipedis 2.1-7.0g, Flos Caryophylli 2.1-7.1g, Lignum Santali Albi 2.1-7.0g, Cortex Cinnamomi 2.1-7.0g, Radix Aristolochiae 6.2-10.0g purifies, pulverize and be coarse powder, mix thoroughly, 90% ethanol percolate extraction with 5 times of weight, flow velocity 12-15 drips/minute, collecting percolate, to be condensed into 60 ℃ of relative densities be 1: 20 extractum, ethanol filter pressing in the medicinal residues purifies the back and reclaims
Get crude drug weight 3.1-3.6 rubber, Colophonium or inferior gelatin doubly and make substrate, get extractum and appropriate hydrochloric acid diphenhydramine mixing is made creme, on substrate, be coated with cream, cutting, lid lining cut into slices product.
According to the characteristics of athletic injury, through theoretic discussion for many years, consulted a large amount of research documents, in conjunction with the experience of clinical practice, we reach a conclusion: athletic injury mostly is deficient syndrome, is the QI and blood deficiency that with the passing of time qi depression to blood stasis causes.The athletic injury later stage, local soft tissue with the clot machineization after, form the fiber granulation tissue, its function can not show a candle to the tissue before injured.The blood vessels that theory of Chinese medical science that Here it is is spoken of are not lived.This moment, local organization was in a kind of state of the blood deficiency stagnation of QI.When damage topical application removing blood stasis medicine is treated, more can increase the weight of QI and blood deficiency simultaneously.If give blood activating and promoting tissue regeneration this moment, the hematonic that nourishes blood, improve blood deficiency disease, make QI and blood unobstructed, then can accelerate the metabolism of cell rapidly, promote the regeneration of tissue, and also have on the function significantly and improve.As not paying attention to improving QI and blood deficiency this moment, still carry out the removing blood stasis dissipating blood stasis simply, then can further consume impairment of QI blood, the functional rehabilitation that delays to organize.Based on this theory, we solve qi-blood deficiency syndrome emphatically in line with the principle of " control wind control blood, blood earlier control wind from going out ", carry out blood activating and promoting tissue regeneration on the one hand, nourish blood enrich blood, the warming the meridian eliminating impediment, be aided with active dissipating blood stasis, expelling wind and cold on the other hand, treating both the principal and secondary aspects of a disease is to improve curative effect effectively.
The inventor thinks that it is the important step of treatment outmoded injury that nourishing blood and promoting blood circulation is enriched blood, and contrary treatment blood staff is answered in treatment, thus adopted Sanguis Draxonis in this prescription principal agent, and consumption up 8.1%.Sanguis Draxonis has the effect of dissipating blood stasis analgesic therapy, hemostasia and promoting granulation." Bencao Jingshu " mentioned: " Sanguis Draxonis, sweet main benefit, salty master disappear the key medicine of dissipating blood stasis blood, tissue regeneration promoting blood ... pain relieving raw meat ... ".Sanguis Draxonis, carries out nourishing blood and promoting blood circulation and enriches blood when causing QI and blood deficiency at blood circulation promoting medicine removing blood stasis consumption gas, avoids empty, the promotion tissue regeneration of QI and blood.
We's principal agent also adopts Radix Angelicae Sinensis, Rhizoma Chuanxiong, Flos Carthami, Olibanum, Radix Dipsaci.Wherein Flos Carthami, Olibanum can not only active dissipating blood stasis, reducing swelling and alleviating pain, and in controlling damage, usually be required to be usefulness mutually, its effect is obviously strengthened.Particularly with compatibilities such as Radix Angelicae Sinensis, Rhizoma Chuanxiongs, function of promoting blood circulation to disperse blood clots is obviously strengthened, the same usefulness of Sanguis Draxonis and Olibanum can be in harmonious proportion vim and vigour.Radix Dipsaci is stated in " book on Chinese herbal medicine is looked for the truth ": " all falling pounces on the folding wound, the swollen and muscles and bones Qu Jie of pain, and the stagnation of QI and blood part can dissipate with this ... first medicine of real genus promoting flow of QI and blood muscles and bones ".As seen it is diffusing tonic that our principal agent has row, continuous decrease wonderful of granulation promoting.
Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Herba lysimachiae capillipedis, the dispersing wind and cold of all dispelling, reducing swelling and alleviating pain has the merit of assisting principal agent to strengthen the dissipating blood stasis for subsidence of swelling analgesic therapy.Simultaneously principal agent has again and promotes the dispel merit of dispersing wind and cold pathogenic warmth of this group medicine, and the justice of " control wind and control blood earlier " is arranged.More than be first group of accessory drugs.Flos Caryophylli, Lignum Santali Albi, Cortex Cinnamomi all can the cold expelling heresies, promoting blood circulation, detumescence pain.Wherein the power of Cortex Cinnamomi warming the meridian dissipating blood stasis is outstanding especially, holds the numbness key medicine under the arm for controlling outmoded injury.It is strong that this counts the equal abnormal smells from the patient virtue of medicine, and the Shang Nenghang gas that stagnates can be strengthened principal agent and bring into play active dissipating blood stasis, the merit of analgesic therapy." card control only rope " said: all deposited showy reiolaena root-barks gnawing pains take no rest person can add Olibanum, Radix Angelicae Pubescentis, the Radix Angelicae Dahuricae, Cortex Cinnamomi ... Deng flavor, its pain is promptly lived.More than be second group of accessory drugs.
Radix Aristolochiae has promoting the circulation of QI to relieve pain, the merit of removing toxic substances and promoting subsidence of swelling, and the justice of tool " the capable then blood of gas is capable " both can be controlled " all pains of airsetting " (seeing " herbal classic is met former "), can control " rheumatism paralysis, lumbago and skelalgia " (seeing " vegetation is the side just ") again.
As fully visible, this prescription based on active dissipating blood stasis, reducing swelling and alleviating pain, nourish blood enrich blood, the blood activating and promoting tissue regeneration QI invigorating, having the effect of expelling wind and cold, warming the meridian eliminating impediment concurrently, is diseases such as treatment outmoded injury, anemofrigid-damp arthralgia, particularly damages the good recipe that later stage and chronic strain merge anemofrigid-damp arthralgia.
Preparation method of the present invention is scientific and reasonable, crude drug adopts alcohol percolation method to extract its active drug composition, add again in the substrate such as rubber, both avoided temperature to grasp the loss of effective components that causes because of high temperature when bad, removed the impurity that does not contain or contain less effective composition again, improved content of effective in the medicine, improved drug effect, make only 1mm of plaster Chinese medicine coating layer thickness, do not influence joint motion after sticking, make the athlete in match, can obtain medical treatment in the training time yet, stick simultaneously and just can play one's part to the full in one day, reach drug effect, easy to use.Can not pollute health and clothes after sticking.This unguentum also can be made the viscose glue retinaculum and use, and can effectively prevent the generation of athletic injury.
Adopting this preparation method preparation process to control by rule of thumb, is the may command course of reaction with scientific methods, thus the quality of control product.The inventive method is free from environmental pollution in addition, does not influence health of operators.The amount that is coated with the diphhydramine hydrochloride that adds before the cream is hypo-allergenic amount.
Wuhan Institute Of Sport's this unguentum of clinical practice is to the treatment of diseases such as old soft tissue injury and neck-shoulder pain, lumbago and leg pain, and effect is rather good, and fracture, dislocation back are recovered and other soft tissue injury treatments, and effective percentage is more than 90%.
Hubei Province does clinical trial directly under machine-operated out-patient department with this unguentum, and its test situation is as follows:
Case 138 examples, wherein male 84 examples, women 54 examples, the age is 13-87 year, average 54.6 years old.Government functionary 75 people wherein, retired personnel 34 people, teacher 14 people, athlete 9 people, student 6 people.
Outmoded injury 48 examples (muscular strain 22 examples, joint 26 examples)
Neck-shoulder pain, lumbago and leg pain 79 examples (cervicodynia 21 examples, shoulder pain 35 examples, lumbago and skelalgia 23 examples)
Cold pain 11 examples that cause of rheumatism
The curative effect statistics: total effective rate is 95.6%
Cure (transference cure) 77 examples, account for 55.8%
Produce effects (symptom obviously alleviates) 37 examples account for 26.8%
Effectively (doing well,improving) 18 examples account for 13.0%
Invalid (cardinal symptom does not have improvement) 6 examples account for 4.4%
Following table is enumerated prescription formulation Example of the present invention:
Enumerate model case below with the treatment of this unguentum:
Example 1, Mrs Yang, 52 years old, the doctor of Chengdu Physical Culture Inst..Suffered from waist in 92 years and ache, companion's waist limitation of activity stands up and rises and sits back and waits that action all feels difficult.Influence life and sleep.Do not have obvious trauma history, 5 years pain history are once arranged.Undirected lower limb radiating pain.Health check-up: waist and buttocks pars muscularis have obvious pressure pain point, do not have streak tuberosity.The straight-leg raising test feminine gender.The X line is no abnormal.Be diagnosed as " chronic lumbar muscle strain ", give " blood circulation activating plaster " external application.First pasted after 10 minutes, and waist is ached and begun to alleviate, and second, waist only has slightly ached slightly.Can finish and sit back and wait action.The 5th day, the lumbago complete obiteration.Waist is movable normal, and waist and gluteus pressure pain point disappear.Advise and continue to paste five.Follow up a case by regular visits to 3 years surplus, the recurrence.
Example 2 is opened the coach, man, 60 years old.Wuhan Institute Of Sport.Unknown cause gradually plays right ancon pain before 1 year, aggravation when routine boiled water, twist a towel etc. moves.No swelling ecchymosis etc.Alleviate after the physical therapy for several times, do not draw attention.Have repeatedly during the back state of an illness.Before 6 days, right ancon pain increases the weight of, action, the commentaries on classics of not getting better after the physical therapy such as can not finish down boiled water, twist a towel.Health check-up: MILL ' S levies the positive, and right condylus lateralis humeri tenderness is obvious.Be diagnosed as " right external humeral epicondylitis ".Give " blood circulation activating plaster " external application.Feeling promptly on the 1st that right elbow is ached is clearly better, and can very reluctantly finish down actions such as boiled water.The 4th day, the disappearance of aching of right elbow.The 7th, when action such as twisting a towel, right elbow does not have ached.MILL ' S levies feminine gender.

Claims (3)

1, new blood circulation activating plaster prescription, it is characterized in that by
Sanguis Draxonis 2.0-10.0g Radix Angelicae Sinensis 2.1-7.0g
Rhizoma Chuanxiong 6.2-10.0g Flos Carthami 2.1-7.0g
Olibanum 6.2-10.0g Radix Dipsaci 6.2-10.0
Rhizoma Et Radix Notopterygii 6.2-10.0g Radix Angelicae Pubescentis 6.2-10.0g
Radix Angelicae Dahuricae 6.2-10.0g Herba lysimachiae capillipedis 2.1-7.0g
Flos Caryophylli 2.1-7.1g Lignum Santali Albi 2.1-7.0g
6.2-10.0g is formulated for Cortex Cinnamomi 2.1-7.0g Radix Aristolochiae.
2, new blood circulation activating plaster preparation method, it is characterized in that, get Sanguis Draxonis 2-10g, Radix Angelicae Sinensis 2.1-7.0g, Rhizoma Chuanxiong 6.2-10.0g, Flos Carthami 2.1-7.0g, Olibanum 6.2-10.0g, Radix Dipsaci 6.2-10.0, Rhizoma Et Radix Notopterygii 6.2-10.0g, Radix Angelicae Pubescentis 6.2-10.0g, Radix Angelicae Dahuricae 6.2-10.0g, Herba lysimachiae capillipedis 2.1-7.0g, Flos Caryophylli 2.1-7.1g, Lignum Santali Albi 2.1-7.0g, Cortex Cinnamomi 2.1-7.0g, Radix Aristolochiae 6.2-10.0g purifies, pulverize and be coarse powder, mix thoroughly, 90% ethanol percolate extraction with 5 times of weight, flow velocity 12-15 drips/minute, collecting percolate, to be condensed into 60 ℃ of relative densities be 1: 20 extractum, ethanol filter pressing in the medicinal residues purifies the back and reclaims
Get crude drug weight 3.1-3.6 rubber doubly, Colophonium or inferior gelatin are made substrate, get extractum and appropriate hydrochloric acid diphenhydramine mixing is made creme, are coated with cream on substrate, cutting, lid lining cut into slices product.
3, method according to claim 2, the amount that it is characterized in that adding diphhydramine hydrochloride is hypo-allergenic amount.
CN 98113478 1998-03-20 1998-03-20 Process for preparing prescription and medicinal extract of plaster for activating meridians Expired - Fee Related CN1060394C (en)

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Application Number Priority Date Filing Date Title
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CN1191138A true CN1191138A (en) 1998-08-26
CN1060394C CN1060394C (en) 2001-01-10

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108686146A (en) * 2018-07-12 2018-10-23 李朝阳 A kind of Dressed plaster promoting blood circulation and removing blood stasis and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108686146A (en) * 2018-07-12 2018-10-23 李朝阳 A kind of Dressed plaster promoting blood circulation and removing blood stasis and preparation method thereof
CN108686146B (en) * 2018-07-12 2021-03-16 李朝阳 Externally applied plaster for promoting blood circulation to remove blood stasis and preparation method thereof

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