CN118546165A - 青蒿素衍生的三聚体和四聚体及其用途 - Google Patents
青蒿素衍生的三聚体和四聚体及其用途 Download PDFInfo
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- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
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| PCT/US2018/062356 WO2019104247A1 (en) | 2017-11-21 | 2018-11-21 | Artemisinin-derived trimers and tetramers and their use thereof |
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| CA3131244A1 (en) * | 2019-02-26 | 2020-09-03 | Mahmoud A. Eisohly | Selected artemisinin dimers for the treatment of lashmaniasis |
| CN113264946A (zh) * | 2021-05-11 | 2021-08-17 | 中国人民解放军陆军军医大学第一附属医院 | 一种双氢青蒿素衍生物及其在制备治疗、预防脑血管病药物中的应用 |
| CN115282145A (zh) * | 2022-09-05 | 2022-11-04 | 中南大学湘雅二医院 | 青蒿琥酯在制备治疗青光眼的药物或制剂中的应用 |
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| US9314460B1 (en) | 2013-04-09 | 2016-04-19 | Stc.Unm | Method for cancer cell reprogramming |
| CN105078964A (zh) | 2015-08-20 | 2015-11-25 | 桂林医学院附属医院 | 青蒿琥酯在制备治疗特发性肺纤维化药物中的应用 |
| CN111372583B (zh) * | 2017-11-21 | 2024-06-14 | 赵鸣 | 青蒿素衍生的三聚体和四聚体及其用途 |
| CN109467565B (zh) | 2018-08-16 | 2020-07-10 | 云白药征武科技(上海)有限公司 | 双氢青蒿素三聚体及其制备方法和应用 |
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2018
- 2018-11-21 CN CN201880075374.6A patent/CN111372583B/zh active Active
- 2018-11-21 CN CN202410656901.XA patent/CN118546165A/zh active Pending
- 2018-11-21 EP EP18882235.7A patent/EP3713566A4/en active Pending
- 2018-11-21 US US16/755,562 patent/US11358970B2/en active Active
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- 2018-11-21 JP JP2020523749A patent/JP7282294B2/ja active Active
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2022
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| CN111372583B (zh) | 2024-06-14 |
| JP7282294B2 (ja) | 2023-05-29 |
| WO2019104247A1 (en) | 2019-05-31 |
| EP3713566A1 (en) | 2020-09-30 |
| US20210079011A1 (en) | 2021-03-18 |
| EP3713566A4 (en) | 2021-07-14 |
| CN111372583A (zh) | 2020-07-03 |
| US12134624B2 (en) | 2024-11-05 |
| US20220275003A1 (en) | 2022-09-01 |
| JP2021504302A (ja) | 2021-02-15 |
| US11358970B2 (en) | 2022-06-14 |
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