CN118401502A - 作为rxfp1受体激动剂的苯并噻唑、苯并异噁唑和苯并二噁茂类似物 - Google Patents
作为rxfp1受体激动剂的苯并噻唑、苯并异噁唑和苯并二噁茂类似物 Download PDFInfo
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- CN118401502A CN118401502A CN202280082604.8A CN202280082604A CN118401502A CN 118401502 A CN118401502 A CN 118401502A CN 202280082604 A CN202280082604 A CN 202280082604A CN 118401502 A CN118401502 A CN 118401502A
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163289830P | 2021-12-15 | 2021-12-15 | |
| US63/289,830 | 2021-12-15 | ||
| PCT/US2022/081519 WO2023114822A1 (en) | 2021-12-15 | 2022-12-14 | Benzothiazole, benzoisoxazole and benzodioxole analogs as rxfp1 receptor agonists |
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| CN118401502A true CN118401502A (zh) | 2024-07-26 |
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| CN202280082604.8A Pending CN118401502A (zh) | 2021-12-15 | 2022-12-14 | 作为rxfp1受体激动剂的苯并噻唑、苯并异噁唑和苯并二噁茂类似物 |
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| US (1) | US20250066344A1 (https=) |
| EP (1) | EP4448500A1 (https=) |
| JP (1) | JP2025501509A (https=) |
| KR (1) | KR20240120745A (https=) |
| CN (1) | CN118401502A (https=) |
| WO (1) | WO2023114822A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2025106780A1 (en) * | 2023-11-17 | 2025-05-22 | Eli Lilly And Company | Rxfp1 receptor agonists |
| WO2025235833A1 (en) * | 2024-05-10 | 2025-11-13 | Eli Lilly And Company | Rxfp1 receptor agonists |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013165606A1 (en) * | 2012-05-04 | 2013-11-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Modulators of the relaxin receptor 1 |
| CN106316987B (zh) * | 2015-07-03 | 2020-11-17 | 江苏恒瑞医药股份有限公司 | 苯甲酰胺类衍生物、其制备方法及其在医药上的应用 |
| WO2019057969A1 (en) * | 2017-09-22 | 2019-03-28 | Johann Wolfgang Goethe-Universität | DOUBLE AGONISTS OF FXR AND PPARδ, AND USES THEREOF |
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2022
- 2022-12-14 WO PCT/US2022/081519 patent/WO2023114822A1/en not_active Ceased
- 2022-12-14 JP JP2024535921A patent/JP2025501509A/ja active Pending
- 2022-12-14 EP EP22859491.7A patent/EP4448500A1/en active Pending
- 2022-12-14 US US18/718,477 patent/US20250066344A1/en active Pending
- 2022-12-14 KR KR1020247023154A patent/KR20240120745A/ko active Pending
- 2022-12-14 CN CN202280082604.8A patent/CN118401502A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20250066344A1 (en) | 2025-02-27 |
| KR20240120745A (ko) | 2024-08-07 |
| JP2025501509A (ja) | 2025-01-22 |
| EP4448500A1 (en) | 2024-10-23 |
| WO2023114822A1 (en) | 2023-06-22 |
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