KR20240120745A - Rxfp1 수용체 효능제로서의 벤조티아졸, 벤조이속사졸 및 벤조디옥솔 유사체 - Google Patents
Rxfp1 수용체 효능제로서의 벤조티아졸, 벤조이속사졸 및 벤조디옥솔 유사체 Download PDFInfo
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- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
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- C07—ORGANIC CHEMISTRY
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- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
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- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163289830P | 2021-12-15 | 2021-12-15 | |
| US63/289,830 | 2021-12-15 | ||
| PCT/US2022/081519 WO2023114822A1 (en) | 2021-12-15 | 2022-12-14 | Benzothiazole, benzoisoxazole and benzodioxole analogs as rxfp1 receptor agonists |
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| KR20240120745A true KR20240120745A (ko) | 2024-08-07 |
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| KR1020247023154A Pending KR20240120745A (ko) | 2021-12-15 | 2022-12-14 | Rxfp1 수용체 효능제로서의 벤조티아졸, 벤조이속사졸 및 벤조디옥솔 유사체 |
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| US (1) | US20250066344A1 (https=) |
| EP (1) | EP4448500A1 (https=) |
| JP (1) | JP2025501509A (https=) |
| KR (1) | KR20240120745A (https=) |
| CN (1) | CN118401502A (https=) |
| WO (1) | WO2023114822A1 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2025106780A1 (en) * | 2023-11-17 | 2025-05-22 | Eli Lilly And Company | Rxfp1 receptor agonists |
| WO2025235833A1 (en) * | 2024-05-10 | 2025-11-13 | Eli Lilly And Company | Rxfp1 receptor agonists |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013165606A1 (en) * | 2012-05-04 | 2013-11-07 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Modulators of the relaxin receptor 1 |
| CN106316987B (zh) * | 2015-07-03 | 2020-11-17 | 江苏恒瑞医药股份有限公司 | 苯甲酰胺类衍生物、其制备方法及其在医药上的应用 |
| WO2019057969A1 (en) * | 2017-09-22 | 2019-03-28 | Johann Wolfgang Goethe-Universität | DOUBLE AGONISTS OF FXR AND PPARδ, AND USES THEREOF |
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2022
- 2022-12-14 WO PCT/US2022/081519 patent/WO2023114822A1/en not_active Ceased
- 2022-12-14 JP JP2024535921A patent/JP2025501509A/ja active Pending
- 2022-12-14 EP EP22859491.7A patent/EP4448500A1/en active Pending
- 2022-12-14 US US18/718,477 patent/US20250066344A1/en active Pending
- 2022-12-14 KR KR1020247023154A patent/KR20240120745A/ko active Pending
- 2022-12-14 CN CN202280082604.8A patent/CN118401502A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20250066344A1 (en) | 2025-02-27 |
| JP2025501509A (ja) | 2025-01-22 |
| EP4448500A1 (en) | 2024-10-23 |
| WO2023114822A1 (en) | 2023-06-22 |
| CN118401502A (zh) | 2024-07-26 |
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