CN118161577A - Coix seed and chrysanthemum liver-regulating granule and preparation method thereof - Google Patents

Coix seed and chrysanthemum liver-regulating granule and preparation method thereof Download PDF

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Publication number
CN118161577A
CN118161577A CN202410307063.5A CN202410307063A CN118161577A CN 118161577 A CN118161577 A CN 118161577A CN 202410307063 A CN202410307063 A CN 202410307063A CN 118161577 A CN118161577 A CN 118161577A
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liver
chrysanthemum
raw materials
regulating
bran
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刘振宝
于伟
丁新春
展爽
刘明亮
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Harbin Zhizhentang Traditional Chinese Medicine Clinic Co ltd
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Harbin Zhizhentang Traditional Chinese Medicine Clinic Co ltd
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994—Coix (Job's tears)
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Abstract

The invention relates to a pearl barley and chrysanthemum liver regulating granule and a preparation method thereof. The liver-regulating granule is prepared from coix seed, fingered citron, chrysanthemum, vinegar-processed nutgrass galingale rhizome, white peony root, prepared rehmannia root, dried orange peel, chinese angelica, bran-fried Chinese yam, moutan bark and the like serving as raw materials, and has the effects of nourishing yin, clearing liver heat, tonifying liver and kidney, tonifying qi, regulating blood, strengthening spleen and promoting diuresis. Can be used for treating consumptive disease, deficiency of qi and blood, weakness of spleen and stomach, bitter taste, dry throat, palpitation, anorexia, inappetence, female menstrual disorder, etc. The preparation is completed through the steps of soaking, decocting, concentrating, preparing particles, drying and the like, and the preparation method is simple in process, low in production cost and convenient to put into production and apply.

Description

Coix seed and chrysanthemum liver-regulating granule and preparation method thereof
Technical Field
The invention relates to the technical field of traditional Chinese medicine preparations, in particular to pearl barley and chrysanthemum liver regulating particles and a preparation method thereof.
Background
The traditional Chinese medicine considers that the liver is the shield for expelling toxin of human body, and has three physiological functions, namely, one for storing blood, two for dredging and discharging, and three for regulating tendons. The liver is strong, and is an important guarantee for human immunity and health. If liver function is reduced, blood storage deficiency, disorder of drainage, difficulty in flexing and stretching tendons and joints, general weakness, vision deterioration, blurred vision, disease resistance of organism and various diseases can occur when the diseases are deficient. Reasonable traditional Chinese medicine conditioning is beneficial to liver conditioning and improves physical health.
Disclosure of Invention
In view of the problems existing in the prior art, the invention discloses a pearl barley and chrysanthemum liver regulating granule which comprises the following main components in parts by weight: 50-100g of coix seed, 80-120g of fingered citron, 30-70g of chrysanthemum, 30-70g of vinegar nutgrass galingale rhizome, 80-120g of white paeony root, 80-120g of prepared rehmannia root, 30-70g of dried orange peel, 80-120g of Chinese angelica, 80-120g of bran-fried Chinese yam, 50-70g of tree peony bark, 30-70g of liquorice, 50-70g of bran-fried immature bitter orange, 40-60g of vinegar north bupleurum root, 90-110g of poria cocos, 50-100g of shizandra berry and 1-10g of ganoderma lucidum spore.
As a preferred scheme of the invention, the main components of the pearl barley and chrysanthemum liver-regulating granule comprise 80g of coix seed, 100g of fingered citron, 50g of chrysanthemum, 50g of vinegar nutgrass galingale rhizome, 100g of white peony root, 100g of prepared rehmannia root, 50g of dried orange peel, 100g of Chinese angelica, 100g of Chinese yam stir-fried with bran, 60g of tree peony bark, 50g of liquorice, 60g of immature bitter orange stir-fried with bran, 50g of bupleurum chinense, 100g of poria cocos, 80g of shizandra berry and 5g of ganoderma lucidum spores.
A preparation method of pearl barley liver regulating particles is characterized by comprising the following steps:
Firstly, preparing raw materials according to the amount, adding water which is 7 times the weight of the raw materials into the raw materials, and soaking for 1 hour;
Step two, decocting the soaked raw materials twice, wherein the first decoction is carried out for 60 minutes, the second decoction is carried out for 50 minutes, and the decoction is kept stand and cooled to room temperature;
Step three, filtering the cooled decoction, and heating and concentrating the filtrate to obtain concentrated solution;
And step four, adding dextrin and povidone k30 aqueous solution into the concentrated solution, granulating, and drying to obtain the coix seed and chrysanthemum liver regulating particles.
As a preferred embodiment of the invention, the concentrate obtained in step three has a relative density of 1.25-1.35kg/m 3 measured at 70 ℃.
As a preferred embodiment of the present invention, the drying temperature in the fourth step is 75-85 ℃.
Semen Coicis, named Coicis semen, and fructus oryzae Sativae. Has effects of invigorating spleen, eliminating dampness, relieving arthralgia, relieving diarrhea, clearing heat and removing blood stasis. Mainly treats edema, beriberi, difficult urination, damp arthralgia, contracture, spleen deficiency diarrhea, pulmonary abscess and acute appendicitis. Sweet and bland in flavor and slightly cold in nature. Enter spleen meridian, stomach meridian and lung meridian.
Flos Chrysanthemi, herba Artemisiae Anomalae, solar essence, female node, flos Matricariae Chamomillae, female stem, radix Santali albi, zhou Ying, fu Yannian, YINCHENG, flos Chrysanthemi, ZHENJU, JINJING, jin Rui, trovain, herba Hosta, and stevia. Has effects of dispelling pathogenic wind, clearing heat, suppressing hyperactive liver, improving eyesight, removing toxic substances, and relieving swelling. Is mainly used for treating exogenous wind or wind-warm onset, fever, headache, dizziness, conjunctival congestion, swelling and pain, furuncle and toxic swelling. Sweet and bitter in flavor and slightly cold in nature. It enters lung and liver meridians.
The prepared rehmannia root has the effects of enriching blood and nourishing, and replenishing essence and marrow. Is mainly used for treating sallow complexion, dizziness, palpitation, irregular menstruation, metrorrhagia, liver and kidney yin deficiency, hectic fever, night sweat, spermatorrhea, impotence, infertility, soreness and weakness of waist and knees, tinnitus, deafness, dizziness, premature gray hair, diabetes, constipation, kidney deficiency and dyspnea. Sweet in flavor and warm in nature. It enters liver and kidney meridians.
Dried orange peel, alias orange peel, noble old, red peel, huang Jupi, wide orange peel, xinhui peel, orange peel and wide orange peel. Has effects of regulating qi-flowing, invigorating spleen, regulating middle warmer, eliminating dampness, and eliminating phlegm. It is used for treating abdominal distention, pain, dyspepsia, chest distress, abdominal distention, anorexia, and loose stool due to stagnation of spleen-stomach qi. Bitter and pungent in flavor and warm in nature. Enter lung and spleen meridians.
Dang Gui, shi Gui and Qin Gui. Has effects of replenishing blood, promoting blood circulation, regulating menstruation, relieving pain, moistening dryness, and smoothing intestine. It is used for treating menoxenia, amenorrhea, dysmenorrhea, abdominal mass, metrorrhagia, asthenia cold, abdominal pain, paralysis, skin numbness, intestinal dryness, constipation, red dysentery, carbuncle, pyocutaneous disease, and traumatic injury. Bitter in flavor and warm in nature. Enters the heart, liver and spleen meridians.
Cortex moutan, cortex moutan radicis, flos Cynomorii, and cortex moutan. Has effects of clearing heat, promoting blood circulation and removing blood stasis. Is used for treating heat of warm disease into blood, with symptoms of macula, epistaxis, hectic fever due to yin deficiency, amenorrhea due to blood stagnation, dysmenorrhea, carbuncle, skin sore, traumatic injury, and rheumatic arthralgia. Pungent and bitter in flavor and slightly cold in nature. It enters heart, liver and kidney meridians.
Glycyrrhrizae radix, radix Angelicae Pubescentis, glycyrrhrizae radix, radix Rubiae Yunnanensis, glycyrrhrizae radix, herba Potentillae Discoloris, mel, herba Melissae axillaris, and radix Petasitis Gracilii. Has effects of invigorating spleen and replenishing qi, clearing heat and detoxicating, eliminating phlegm and relieving cough, relieving spasm and pain, and harmonizing various medicines, and can be used for treating spleen and stomach weakness, listlessness debilitation, palpitation and short breath, cough with excessive phlegm, abdominal pain, limb spasm pain, carbuncle, swelling and sore. Sweet in flavor and neutral in nature. It enters heart, lung, spleen and stomach meridians.
Immature bitter orange, immature bitter orange with goose eye. Has effects of breaking qi, relieving stuffiness, eliminating phlegm and resolving food stagnation. Is mainly used for treating chest and abdominal distention, chest obstruction, distention and pain, phlegm nodule, edema, food stagnation, constipation, gastroptosis, uterine prolapse and rectocele. Bitter and pungent in flavor and cold in nature. It enters spleen, stomach, liver and heart meridians.
Radix bupleuri, fumigated with the name of ground, BIHU, SHANCAI, RUCAO, and CHAICAO. Has effects of relieving exterior and interior syndrome, dispersing stagnated liver qi, and invigorating yang. Is mainly used for treating cold and heat, chest fullness and hypochondriac pain, bitter taste in mouth and deafness, headache and dizziness, malaria, rectocele, irregular menstruation and hysteroptosis. Bitter and pungent in flavor and slightly cold in nature. It enters liver and gallbladder meridians.
Poria, also called Poria cocos, semen Cuscutae and pine needle, can be used for food, without dead surface, pine potato, pine cassava and pine needle. Has effects of removing dampness, promoting diuresis, invigorating spleen, regulating stomach function, and tranquilizing mind. Is mainly used for treating difficult urination, edema, phlegm-fluid retention, cough, vomiting, spleen deficiency, anorexia, diarrhea, palpitation, insomnia, amnesia, spermatorrhea and white turbidity. Sweet and light in taste and neutral in nature. It enters heart, spleen and lung meridians.
Fructus Schisandrae chinensis, radix Angelicae sinensis, fructus fici Pumilae, fructus Zanthoxyli. Has effects of astringing, invigorating qi, promoting salivation, calming heart, and tranquilizing mind. It is used for treating cough, asthma, nocturnal emission, enuresis, chronic diarrhea, spontaneous perspiration, night sweat, body fluid deficiency, thirst, palpitation, and insomnia. Sour taste and warm nature. Enter lung and kidney meridians.
The invention has the beneficial effects that: the liver-regulating granule is prepared from coix seed, fingered citron, chrysanthemum, vinegar-processed nutgrass galingale rhizome, white peony root, prepared rehmannia root, dried orange peel, chinese angelica, bran-fried Chinese yam, moutan bark and the like serving as raw materials, and has the effects of nourishing yin, clearing liver heat, tonifying liver and kidney, tonifying qi, regulating blood, strengthening spleen and promoting diuresis. Can be used for treating consumptive disease, deficiency of qi and blood, weakness of spleen and stomach, bitter taste, dry throat, palpitation, anorexia, inappetence, female menstrual disorder, etc. The preparation is completed through the steps of soaking, decocting, concentrating, preparing particles, drying and the like, and the preparation method is simple in process, low in production cost and convenient to put into production and apply.
Detailed Description
Example 1
The invention relates to a pearl barley and chrysanthemum liver regulating granule and a preparation method thereof, which specifically comprises the following steps:
Step one, preparing raw materials according to 50g of coix seed, 80g of fingered citron, 30g of chrysanthemum, 30g of vinegar nutgrass galingale rhizome, 80g of white paeony root, 80g of prepared rehmannia root, 30g of dried orange peel, 80g of Chinese angelica, 80g of Chinese yam stir-fried with bran, 50g of tree peony bark, 30g of liquorice, 50g of immature bitter orange stir-fried with bran, 40g of bupleurum chinense, 90g of poria cocos, 50g of shizandra berry and 1g of ganoderma lucidum spore, adding water with the weight which is 7 times that of the raw materials into the raw materials, and soaking for 1 hour;
Step two, decocting the soaked raw materials twice, wherein the first decoction is carried out for 60 minutes, the second decoction is carried out for 50 minutes, and the decoction is kept stand and cooled to room temperature;
Step three, filtering the cooled decoction, heating and concentrating the filtrate, and completing concentration when the relative density is 1.25kg/m 3 at 70 ℃ to obtain concentrated solution;
and fourthly, adding dextrin and povidone k30 aqueous solution into the concentrated solution, granulating, and drying at the temperature of 75 ℃ to obtain the coix seed and chrysanthemum liver regulating particles.
Example 2
The invention relates to a pearl barley and chrysanthemum liver regulating granule and a preparation method thereof, which specifically comprises the following steps:
Step one, preparing raw materials according to 100g of coix seed, 120g of fingered citron, 70g of chrysanthemum, 70g of vinegar nutgrass galingale rhizome, 120g of white peony root, 120g of prepared rehmannia root, 70g of dried orange peel, 120g of Chinese angelica, 120g of Chinese yam stir-fried with bran, 70g of tree peony bark, 70g of liquorice, 70g of immature bitter orange stir-fried with bran, 60g of bupleurum chinense, 110g of poria cocos, 100g of shizandra berry and 10g of ganoderma lucidum spores, adding water with the weight which is 7 times that of the raw materials into the raw materials, and soaking for 1 hour;
Step two, decocting the soaked raw materials twice, wherein the first decoction is carried out for 60 minutes, the second decoction is carried out for 50 minutes, and the decoction is kept stand and cooled to room temperature;
step three, filtering the cooled decoction, heating and concentrating the filtrate, and completing concentration when the relative density is 1.35kg/m 3 at 70 ℃ to obtain concentrated solution;
step four, adding dextrin and povidone k30 aqueous solution into the concentrated solution, granulating, and drying at 85 ℃ to obtain the coix seed and chrysanthemum liver-regulating particles
Example 3
The invention relates to a pearl barley and chrysanthemum liver regulating granule and a preparation method thereof, which specifically comprises the following steps:
Step one, preparing raw materials according to 80g of coix seed, 100g of fingered citron, 50g of chrysanthemum, 50g of vinegar nutgrass galingale rhizome, 100g of white paeony root, 100g of prepared rehmannia root, 50g of dried orange peel, 100g of Chinese angelica, 100g of Chinese yam stir-fried with bran, 60g of tree peony bark, 50g of liquorice, 60g of immature bitter orange stir-fried with bran, 50g of bupleurum chinense, 100g of poria cocos, 80g of shizandra berry and 5g of ganoderma lucidum spores, adding water with the weight which is 7 times that of the raw materials into the raw materials, and soaking for 1 hour;
Step two, decocting the soaked raw materials twice, wherein the first decoction is carried out for 60 minutes, the second decoction is carried out for 50 minutes, and the decoction is kept stand and cooled to room temperature;
Step three, filtering the cooled decoction, heating and concentrating the filtrate, and completing concentration when the relative density is 1.3kg/m 3 at 70 ℃ to obtain concentrated solution;
and fourthly, adding dextrin and povidone k30 aqueous solution into the concentrated solution, granulating, and drying at the temperature of 80 ℃ to obtain the coix seed and chrysanthemum liver regulating particles.
The components not described in detail herein are prior art.
Although the specific embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes and modifications without inventive labor may be made within the scope of the present invention without departing from the spirit of the present invention, which is within the scope of the present invention.

Claims (5)

1. The pearl barley and chrysanthemum liver regulating granule is characterized by comprising the following main components in parts by weight: 50-100g of coix seed, 80-120g of fingered citron, 30-70g of chrysanthemum, 30-70g of vinegar nutgrass galingale rhizome, 80-120g of white paeony root, 80-120g of prepared rehmannia root, 30-70g of dried orange peel, 80-120g of Chinese angelica, 80-120g of bran-fried Chinese yam, 50-70g of tree peony bark, 30-70g of liquorice, 50-70g of bran-fried immature bitter orange, 40-60g of vinegar north bupleurum root, 90-110g of poria cocos, 50-100g of shizandra berry and 1-10g of ganoderma lucidum spore.
2. The liver regulating pearl barley and chrysanthemum particle according to claim 1, wherein: comprises 80g of coix seed, 100g of fingered citron, 50g of chrysanthemum, 50g of vinegar-processed nutgrass galingale rhizome, 100g of white paeony root, 100g of prepared rehmannia root, 50g of dried orange peel, 100g of Chinese angelica, 100g of Chinese yam stir-fried with bran, 60g of tree peony bark, 50g of liquorice, 60g of immature bitter orange stir-fried with bran, 50g of bupleurum chinense, 100g of poria cocos, 80g of shizandra berry and 5g of ganoderma lucidum spore.
3. The preparation method of the pearl barley liver regulating granule as claimed in claim 1, which is characterized by comprising the following steps:
Firstly, preparing raw materials according to the amount, adding water which is 7 times the weight of the raw materials into the raw materials, and soaking for 1 hour;
Step two, decocting the soaked raw materials twice, wherein the first decoction is carried out for 60 minutes, the second decoction is carried out for 50 minutes, and the decoction is kept stand and cooled to room temperature;
Step three, filtering the cooled decoction, and heating and concentrating the filtrate to obtain concentrated solution;
And step four, adding dextrin and povidone k30 aqueous solution into the concentrated solution, granulating, and drying to obtain the coix seed and chrysanthemum liver regulating particles.
4. The method for preparing the pearl barley liver regulating granule according to claim 3, wherein the method comprises the following steps: the relative density of the concentrated solution obtained in the third step is 1.25-1.35kg/m 3 at 70 ℃.
5. The method for preparing the pearl barley liver regulating granule according to claim 3, wherein the method comprises the following steps: in the fourth step, the drying temperature is 75-85 ℃.
CN202410307063.5A 2024-03-18 2024-03-18 Coix seed and chrysanthemum liver-regulating granule and preparation method thereof Pending CN118161577A (en)

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