CN118139869A - 异丙基-d-吡喃葡萄糖苷衍生物、制备方法及其用途 - Google Patents

异丙基-d-吡喃葡萄糖苷衍生物、制备方法及其用途 Download PDF

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Publication number
CN118139869A
CN118139869A CN202280071353.3A CN202280071353A CN118139869A CN 118139869 A CN118139869 A CN 118139869A CN 202280071353 A CN202280071353 A CN 202280071353A CN 118139869 A CN118139869 A CN 118139869A
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China
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tritium
deuterium
hydrogen
propyl
methyl
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Pending
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CN202280071353.3A
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English (en)
Chinese (zh)
Inventor
陈令仪
王翊
廖彣玲
李育棠
吕亭萱
黄郁文
李家维
王贞
陈方仪
焦传金
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Publication of CN118139869A publication Critical patent/CN118139869A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Otolaryngology (AREA)
CN202280071353.3A 2021-10-25 2022-10-25 异丙基-d-吡喃葡萄糖苷衍生物、制备方法及其用途 Pending CN118139869A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163271411P 2021-10-25 2021-10-25
US63/271,411 2021-10-25
PCT/CN2022/127414 WO2023072085A1 (zh) 2021-10-25 2022-10-25 异丙基-d-吡喃葡萄糖苷衍生物、制备方法及其用途

Publications (1)

Publication Number Publication Date
CN118139869A true CN118139869A (zh) 2024-06-04

Family

ID=86159046

Family Applications (2)

Application Number Title Priority Date Filing Date
CN202280071353.3A Pending CN118139869A (zh) 2021-10-25 2022-10-25 异丙基-d-吡喃葡萄糖苷衍生物、制备方法及其用途
CN202280071472.9A Pending CN118215669A (zh) 2021-10-25 2022-10-25 异野漆树苷及其衍生物用于促进神经修复的用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202280071472.9A Pending CN118215669A (zh) 2021-10-25 2022-10-25 异野漆树苷及其衍生物用于促进神经修复的用途

Country Status (7)

Country Link
US (2) US20250255893A1 (https=)
EP (2) EP4424695A4 (https=)
JP (2) JP2024541121A (https=)
KR (2) KR20240090983A (https=)
CN (2) CN118139869A (https=)
TW (2) TWI898161B (https=)
WO (2) WO2023072069A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101045072A (zh) * 2007-05-08 2007-10-03 胡军 山香圆叶提取物及其医药用途
CN102617658B (zh) * 2012-03-09 2014-08-20 中国烟草总公司郑州烟草研究院 β-紫罗兰醇-β-D-葡糖苷的制备方法及其在烟草加香中的应用
CN102617659A (zh) * 2012-03-09 2012-08-01 中国烟草总公司郑州烟草研究院 α-紫罗兰醇葡糖苷的合成方法及其在卷烟中的加香应用
CN106167508A (zh) * 2016-07-13 2016-11-30 上海应用技术学院 一种具有紫罗兰香味的葡萄糖苷化合物及其制备方法

Also Published As

Publication number Publication date
TW202317142A (zh) 2023-05-01
US20240415859A1 (en) 2024-12-19
JP2024541121A (ja) 2024-11-06
CN118215669A (zh) 2024-06-18
KR20240090982A (ko) 2024-06-21
TWI898161B (zh) 2025-09-21
WO2023072085A1 (zh) 2023-05-04
EP4424694A1 (en) 2024-09-04
EP4424695A1 (en) 2024-09-04
EP4424694A4 (en) 2026-03-11
JP2024539499A (ja) 2024-10-28
EP4424695A4 (en) 2025-10-22
TW202320806A (zh) 2023-06-01
WO2023072069A1 (zh) 2023-05-04
US20250255893A1 (en) 2025-08-14
KR20240090983A (ko) 2024-06-21

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