KR20240090983A - 신경 복원 촉진에 사용되는 이소로이폴린 및 그 유도체의 용도 - Google Patents

신경 복원 촉진에 사용되는 이소로이폴린 및 그 유도체의 용도 Download PDF

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Publication number
KR20240090983A
KR20240090983A KR1020247017446A KR20247017446A KR20240090983A KR 20240090983 A KR20240090983 A KR 20240090983A KR 1020247017446 A KR1020247017446 A KR 1020247017446A KR 20247017446 A KR20247017446 A KR 20247017446A KR 20240090983 A KR20240090983 A KR 20240090983A
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KR
South Korea
Prior art keywords
nerve
isorhoifolin
derivatives
brain
nerve damage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020247017446A
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English (en)
Korean (ko)
Inventor
린이 천
위-런 천
원-링 랴오
이 왕
위-탕 리
팅-쉬안 뤼
자-웨이 리
팡-이 천
촨-진 자오
Original Assignee
린이 천
위-런 천
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Publication date
Application filed by 린이 천, 위-런 천 filed Critical 린이 천
Publication of KR20240090983A publication Critical patent/KR20240090983A/ko
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/07—Benzo[b]pyran-4-ones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Otolaryngology (AREA)
KR1020247017446A 2021-10-25 2022-10-25 신경 복원 촉진에 사용되는 이소로이폴린 및 그 유도체의 용도 Pending KR20240090983A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163271411P 2021-10-25 2021-10-25
US63/271,411 2021-10-25
PCT/CN2022/127372 WO2023072069A1 (zh) 2021-10-25 2022-10-25 异野漆树苷及其衍生物用于促进神经修复的用途

Publications (1)

Publication Number Publication Date
KR20240090983A true KR20240090983A (ko) 2024-06-21

Family

ID=86159046

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020247017446A Pending KR20240090983A (ko) 2021-10-25 2022-10-25 신경 복원 촉진에 사용되는 이소로이폴린 및 그 유도체의 용도
KR1020247017445A Pending KR20240090982A (ko) 2021-10-25 2022-10-25 이소프로필-d-글루코피라노사이드 유도체, 이의 제조방법과 용도

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1020247017445A Pending KR20240090982A (ko) 2021-10-25 2022-10-25 이소프로필-d-글루코피라노사이드 유도체, 이의 제조방법과 용도

Country Status (7)

Country Link
US (2) US20250255893A1 (https=)
EP (2) EP4424695A4 (https=)
JP (2) JP2024541121A (https=)
KR (2) KR20240090983A (https=)
CN (2) CN118139869A (https=)
TW (2) TWI898161B (https=)
WO (2) WO2023072069A1 (https=)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101045072A (zh) * 2007-05-08 2007-10-03 胡军 山香圆叶提取物及其医药用途
CN102617658B (zh) * 2012-03-09 2014-08-20 中国烟草总公司郑州烟草研究院 β-紫罗兰醇-β-D-葡糖苷的制备方法及其在烟草加香中的应用
CN102617659A (zh) * 2012-03-09 2012-08-01 中国烟草总公司郑州烟草研究院 α-紫罗兰醇葡糖苷的合成方法及其在卷烟中的加香应用
CN106167508A (zh) * 2016-07-13 2016-11-30 上海应用技术学院 一种具有紫罗兰香味的葡萄糖苷化合物及其制备方法

Also Published As

Publication number Publication date
TW202317142A (zh) 2023-05-01
US20240415859A1 (en) 2024-12-19
JP2024541121A (ja) 2024-11-06
CN118215669A (zh) 2024-06-18
KR20240090982A (ko) 2024-06-21
TWI898161B (zh) 2025-09-21
WO2023072085A1 (zh) 2023-05-04
EP4424694A1 (en) 2024-09-04
EP4424695A1 (en) 2024-09-04
EP4424694A4 (en) 2026-03-11
JP2024539499A (ja) 2024-10-28
EP4424695A4 (en) 2025-10-22
TW202320806A (zh) 2023-06-01
WO2023072069A1 (zh) 2023-05-04
CN118139869A (zh) 2024-06-04
US20250255893A1 (en) 2025-08-14

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