CN118121661A - Fresh gastrodia elata honey tablet and preparation method thereof - Google Patents

Fresh gastrodia elata honey tablet and preparation method thereof Download PDF

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Publication number
CN118121661A
CN118121661A CN202211542134.7A CN202211542134A CN118121661A CN 118121661 A CN118121661 A CN 118121661A CN 202211542134 A CN202211542134 A CN 202211542134A CN 118121661 A CN118121661 A CN 118121661A
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gastrodia elata
honey
fresh
tablet
fresh gastrodia
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Inventor
李晓明
罗芳
李振华
李东
李健华
李晓福
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Leishan County Fangxiang Village Development Co ltd Shizhang Tianma
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Leishan County Fangxiang Village Development Co ltd Shizhang Tianma
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Priority to CN202211542134.7A priority Critical patent/CN118121661A/en
Publication of CN118121661A publication Critical patent/CN118121661A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/13Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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Abstract

The invention relates to a fresh gastrodia elata honey tablet and a preparation method thereof. In particular, the invention relates to a fresh gastrodia elata honey tablet which is prepared from fresh gastrodia elata and honey directly through a honey preparation process. Compared with the gastrodia elata health care product prepared from dry gastrodia elata, the process disclosed by the invention not only keeps nutrition and medicinal components in the gastrodia elata from losing to the greatest extent, avoids multilayer loss and damage of the nutrition substances caused by multiple processing in the traditional method, but also can avoid the problem of pollution of medicinal materials caused by multiple processing, and the fresh gastrodia elata honey tablet integrated with the fresh gastrodia elata is obtained by adding the angelica sinensis and the ligusticum wallichii into the gastrodia elata honey tablet through a steam distillation process, and can enrich blood, activate blood, dredge channels and activate collaterals.

Description

Fresh gastrodia elata honey tablet and preparation method thereof
Technical Field
The invention relates to the technical field of life science, in particular to a fresh gastrodia elata honey tablet and a preparation method thereof.
Background
The gastrodia elata is taken as a traditional rare traditional Chinese medicinal material in China, is also a common medicinal material which is determined by Wei Jian commission and is used as both food and medicinal material (short for eating medicinal materials) and medicine and food, is taken as an important common health medicinal material in the aspects of resisting senile dementia, regulating immunity and the like at home and abroad, and has wide market prospect in deep research and development. Gastrodia elata is rich in gastrodin, p-hydroxybenzyl alcohol, gastrodia elata polysaccharide, vitamin A, glycosides, alkaloids, vanillyl alcohol, vanillin, succinic acid, beta-sitosterol, mucilage, etc., wherein gastrodin, p-hydroxybenzyl alcohol and gastrodia elata polysaccharide are main components.
The picking period of fresh gastrodia tuber is very concentrated, only about 10-30 days per year, the problem that a large number of products cannot be processed and sold in time can occur in the fresh gastrodia tuber purchasing season, and the serious consequences of decay and deterioration can be brought to cellaring, sand storage and freezing storage.
At present, other reports on the preparation of fresh gastrodia elata honey tablets by using fresh gastrodia elata are not yet seen. There is a need in the market for a process and product for processing fresh gastrodia elata honey tablet using fresh gastrodia elata which can effectively maintain nutrition and medicinal components.
Disclosure of Invention
The invention aims to solve the defects in the prior art and provides a fresh gastrodia elata honey tablet and a preparation method thereof.
In order to achieve the above purpose, the present invention adopts the following technical scheme:
a preparation method of a fresh gastrodia elata honey tablet comprises the following steps:
S1, screening and cleaning: screening and classifying fresh rhizoma Gastrodiae, removing dirt and impurities, cleaning, and peeling;
S2, slicing: slicing fresh gastrodia elata to reach the length of 5-8 cm, the width of 2-4 cm and the thickness of 0.2-1 cm;
s3, color protection: soaking rhizoma Gastrodiae tablet in drinking water in a container, and adding vitamin C into the drinking water for color protection treatment for 1-2min, wherein the addition mass of vitamin C is 0.00005-0.0002 times of the drinking water;
S4, distilling and boiling: collecting volatile oil and distilled residual liquid of radix Angelicae sinensis and rhizoma Ligustici Chuanxiong by steam distillation, decocting residues with water, filtering, collecting filtrate, mixing filtrate with distilled residual liquid, concentrating to obtain fluid extract, adding ethylenediamine tetraacetic acid, sodium pyrophosphate and citric acid for treatment, adding ethylenediamine tetraacetic acid, sodium pyrophosphate and citric acid with the mass of 0.0002 times, 0.0015 times and 0.002 times of that of drinking water respectively, boiling for 2min, and taking out rhizoma Gastrodiae tablet and draining;
S5, honey preparation: adding 80-85% of honey accounting for the addition amount of the formula into the fresh gastrodia elata slices in the step S2 for honey processing for 12-24 hours;
s6, dipping and evaporating to dryness: soaking for 2-10 hours to allow water to fully exude, heating until the sugar juice is thick, steaming until the water content is lower than 50%, adding the rest honey which is uniformly mixed with maltose, soaking the gastrodia elata for 2-10 hours, heating until the sugar juice is thick, and steaming until the water content is lower than 50%;
s7, the following steps: and (3) drying: drying at below 50deg.C to water content of 20-40% to obtain rhizoma Gastrodiae honeyed tablet.
As a further scheme of the invention, the weight ratio of the fresh gastrodia elata to the honey is 100: 5-30, the weight ratio of fresh gastrodia tuber to maltose is 100:0.2 to 2.
As a further scheme of the invention, the weight ratio of the fresh gastrodia elata to the honey is 100:10 to 25.
As a further scheme of the invention, the weight ratio of the fresh gastrodia elata to the honey is 100:10 to 20.
As a further scheme of the invention, the weight ratio of the fresh gastrodia elata to the maltose is 100:0.3 to 1.
As a further scheme of the invention, the weight ratio of the fresh gastrodia elata to the maltose is 100:0.4 to 0.8.
The beneficial effects of the invention are as follows:
1. Compared with the gastrodia elata health care product prepared from dry gastrodia elata, the process disclosed by the invention not only keeps nutrition and medicinal components in the gastrodia elata from losing to the greatest extent, avoids multilayer loss and damage of the nutrition substances caused by multiple processing in the traditional method, but also can avoid the problem of pollution of medicinal materials caused by multiple processing, and the fresh gastrodia elata honey tablet integrated with the fresh gastrodia elata is obtained by adding the angelica sinensis and the ligusticum wallichii into the gastrodia elata honey tablet through a steam distillation process, and can enrich blood, activate blood, dredge channels and activate collaterals.
2. The process adopts the steps of color protection of vitamin C, hardness protection of calcium chloride, honey processing and the like to treat fresh gastrodia elata, wherein the vitamin C has the effect of inhibiting polyphenol oxidase, and the vitamin C has the effect of resisting oxidation when being added into products, and the calcium chloride can play the roles of enhancing nutrition of gastrodia elata, stabilizing fresh feeling of gastrodia elata and solidifying effective components of gastrodia elata.
3. The reducing sugar in the honey can prevent the oxidative decomposition of gastrodin and stabilize the drug effect, removes unpleasant smell in fresh gastrodia elata, can be directly eaten, has better mouthfeel, and can be directly eaten.
Detailed Description
The technical solutions of the embodiments of the present invention will be clearly and completely described in the following in conjunction with the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments.
It should be noted that, without conflict, the embodiments of the present application and features of the embodiments may be combined with each other.
A preparation method of a fresh gastrodia elata honey tablet comprises the following steps:
S1, screening and cleaning: screening and classifying fresh rhizoma Gastrodiae, removing dirt and impurities, cleaning, and peeling;
The fresh gastrodia tuber is directly used for processing, so that the production period is shortened, and the production cost is reduced. The drying treatment process of fresh gastrodia elata is omitted, the fresh gastrodia elata can be processed on site, and the storage and transportation cost of processing dry gastrodia elata products is saved.
S2, slicing: slicing fresh gastrodia elata to reach the length of 5-8 cm, the width of 2-4 cm and the thickness of 0.2-1 cm;
s3, color protection: soaking rhizoma Gastrodiae tablet in drinking water in a container, and adding vitamin C into the drinking water for color protection treatment for 1-2min, wherein the addition mass of vitamin C is 0.00005-0.0002 times of the drinking water;
S4, distilling and boiling: collecting volatile oil and distilled residual liquid of radix Angelicae sinensis and rhizoma Ligustici Chuanxiong by steam distillation, decocting residues with water, filtering, collecting filtrate, mixing filtrate with distilled residual liquid, concentrating to obtain fluid extract, adding ethylenediamine tetraacetic acid, sodium pyrophosphate and citric acid for treatment, adding ethylenediamine tetraacetic acid, sodium pyrophosphate and citric acid with the mass of 0.0002 times, 0.0015 times and 0.002 times of that of drinking water respectively, boiling for 2min, and taking out rhizoma Gastrodiae tablet and draining;
S5, honey preparation: adding 80-85% of honey accounting for the addition amount of the formula into the fresh gastrodia elata slices in the step S2 for honey processing for 12-24 hours;
s6, dipping and evaporating to dryness: soaking for 2-10 hours to allow water to fully exude, heating until the sugar juice is thick, steaming until the water content is lower than 50%, adding the rest honey which is uniformly mixed with maltose, soaking the gastrodia elata for 2-10 hours, heating until the sugar juice is thick, and steaming until the water content is lower than 50%;
s7, the following steps: and (3) drying: drying at below 50deg.C to water content of 20-40% to obtain rhizoma Gastrodiae honeyed tablet.
In this embodiment, the weight ratio of fresh gastrodia elata to honey is 100: 5-30, the weight ratio of fresh gastrodia tuber to maltose is 100:0.2 to 2.
In this embodiment, the weight ratio of fresh gastrodia elata to honey is 100:10 to 25.
In this embodiment, the weight ratio of fresh gastrodia elata to honey is 100:10 to 20.
In this embodiment, the weight ratio of fresh gastrodia elata to maltose is 100:0.3 to 1.
In this embodiment, the weight ratio of fresh gastrodia elata to maltose is 100:0.4 to 0.8.
Compared with a gastrodia elata health-care product prepared from dry gastrodia elata, the process disclosed by the invention not only keeps nutrition and medicinal components in the gastrodia elata from losing to the greatest extent, avoids multilayer loss and damage of nutrients caused by multiple processing in the traditional method, but also can avoid the problem of pollution of medicinal materials caused by multiple processing, and the fresh gastrodia elata honey tablet integrated with the fresh gastrodia elata is obtained by adding the angelica sinensis and the ligusticum wallichii into the gastrodia elata honey tablet through a steam distillation process, so that blood can be enriched, blood can be activated, and menstruation can be cleared and collaterals can be activated;
Further, the process adopts the steps of color protection of vitamin C, hardness protection of calcium chloride, honey processing and the like to treat fresh gastrodia elata, the vitamin C has the effect of inhibiting polyphenol oxidase, the vitamin C is added into the product to play an antioxidant role, the calcium chloride can play the roles of enhancing nutrition of gastrodia elata, stabilizing fresh feeling of gastrodia elata and solidifying effective components of gastrodia elata, and reducing sugar in honey can prevent oxidative decomposition of gastrodin and stabilize drug effect.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of exemplary embodiments according to the present application. As used herein, the singular is also intended to include the plural unless the context clearly indicates otherwise, and furthermore, it is to be understood that the terms "comprises" and/or "comprising" when used in this specification are taken to specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, but various modifications and variations can be made to the present invention by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (6)

1. The preparation method of the fresh gastrodia elata honey tablet is characterized by comprising the following steps of:
S1, screening and cleaning: screening and classifying fresh rhizoma Gastrodiae, removing dirt and impurities, cleaning, and peeling;
S2, slicing: slicing fresh gastrodia elata to reach the length of 5-8 cm, the width of 2-4 cm and the thickness of 0.2-1 cm;
s3, color protection: soaking rhizoma Gastrodiae tablet in drinking water in a container, and adding vitamin C into the drinking water for color protection treatment for 1-2min, wherein the addition mass of vitamin C is 0.00005-0.0002 times of the drinking water;
S4, distilling and boiling: collecting volatile oil and distilled residual liquid of radix Angelicae sinensis and rhizoma Ligustici Chuanxiong by steam distillation, decocting residues with water, filtering, collecting filtrate, mixing filtrate with distilled residual liquid, concentrating to obtain fluid extract, adding ethylenediamine tetraacetic acid, sodium pyrophosphate and citric acid for treatment, adding ethylenediamine tetraacetic acid, sodium pyrophosphate and citric acid with the mass of 0.0002 times, 0.0015 times and 0.002 times of that of drinking water respectively, boiling for 2min, and taking out rhizoma Gastrodiae tablet and draining;
S5, honey preparation: adding 80-85% of honey accounting for the addition amount of the formula into the fresh gastrodia elata slices in the step S2 for honey processing for 12-24 hours;
s6, dipping and evaporating to dryness: soaking for 2-10 hours to allow water to fully exude, heating until the sugar juice is thick, steaming until the water content is lower than 50%, adding the rest honey which is uniformly mixed with maltose, soaking the gastrodia elata for 2-10 hours, heating until the sugar juice is thick, and steaming until the water content is lower than 50%;
S7: and (3) drying: drying at below 50deg.C to water content of 20-40% to obtain rhizoma Gastrodiae honeyed tablet.
2. A fresh gastrodia elata honey tablet prepared according to the method of claim 1, wherein the weight ratio of fresh gastrodia elata to honey is 100: 5-30, the weight ratio of fresh gastrodia tuber to maltose is 100:0.2 to 2.
3. A gastrodia elata honey tablet according to claim 2, wherein the weight ratio of fresh gastrodia elata to honey is 100:10 to 25.
4. A gastrodia elata honey tablet according to claim 3, wherein the weight ratio of fresh gastrodia elata to honey is 100:10 to 20.
5. The gastrodia elata honey tablet according to claim 4, wherein the weight ratio of fresh gastrodia elata to maltose is 100:0.3 to 1.
6. The gastrodia elata honey tablet according to claim 5, wherein the weight ratio of fresh gastrodia elata to maltose is 100:0.4 to 0.8.
CN202211542134.7A 2022-12-02 2022-12-02 Fresh gastrodia elata honey tablet and preparation method thereof Pending CN118121661A (en)

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Application Number Priority Date Filing Date Title
CN202211542134.7A CN118121661A (en) 2022-12-02 2022-12-02 Fresh gastrodia elata honey tablet and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202211542134.7A CN118121661A (en) 2022-12-02 2022-12-02 Fresh gastrodia elata honey tablet and preparation method thereof

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Publication Number Publication Date
CN118121661A true CN118121661A (en) 2024-06-04

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