CN1181205A - Nutritus liquid containing active calcium - Google Patents

Nutritus liquid containing active calcium Download PDF

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Publication number
CN1181205A
CN1181205A CN96120439A CN96120439A CN1181205A CN 1181205 A CN1181205 A CN 1181205A CN 96120439 A CN96120439 A CN 96120439A CN 96120439 A CN96120439 A CN 96120439A CN 1181205 A CN1181205 A CN 1181205A
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China
Prior art keywords
calcium
calcium activated
nutrient solution
water
oyster
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CN96120439A
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尹万升
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  • Coloring Foods And Improving Nutritive Qualities (AREA)
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Abstract

A nutritive liquid containing activated calcium is prepared from activated calcium, cane sugar, honey, haw juice, jujube juice, potassium sorbate and distilled water through dissolving activated calcium and cane sugar in water, mixing their solutions with honey, haw juice and jujube juice, boiling for 2 hrs, addition of potassium sorbate, stirring, filter addition of distilled water, bottling and sealing. Said activated calcium is made up of oyster shell or egg shell through calcine or activating with acetic acid.

Description

A kind of nutrient solution that contains calcium activated
The present invention relates to health-care products, specifically be meant a kind of nutrient solution that contains calcium activated.
Raising along with people's material life, spiritual civilization, cultural quality are also transforming, the mankind have recognized that disease do not want clinical treatment merely, but more should pay attention to motion, strengthen the immunocompetence of body by the health care prevention, extraneous all the undesirable element invasion and attack of opposing reach more healthy, more long-lived purpose.In fact, human calcium deficiency is the common issue with that the whole world faces, and in China, this problem is particularly serious, and calcium deficiency has the factor of congenital heredity, but mainly owing to lack of proper care after one's birth and cause, and this and China its people's diet structure has substantial connection.China its people are always based on vegetarian diet, and calcareous in the vegetarian diet disturbed by oxalic acid, phytic acid in the plant, and human body is difficult for absorbing.Dairy products calcium content height is easily inhaled body by human body again, however majority do not like to eat, this is the weakness of China's diet structure, also is the major reason of national calcium deficiency.Even more serious is, for a long time, China's medical circle always think China its people not calcium deficiency, the understanding of calcium is had prejudice, also not too pay attention to clinically.1989, Chinese medicine circle broke out a flash-news, and assistant researcher Mr. Mi Shaoceng of Traumatic Orthopedics Inst., Jishuitan Hospital, Beijing draws a surprising conclusion through research for many years: " calcium content has all been marked in all calcium agent of China wrong.' calcium content ' that pharmaceutical production producer indicates in medicine is ' salt content ' in fact, and specified consumption every day by salt content mistakenly, and the consumption that causes the doctor to indiscriminately imitate producer's regulation is prescribed." like this, countless patients have only taken the 9%-12% that should obey the calcium amount.That is to say, if your calcium deficiency, and the every day 3 times of following the doctor's advice, when obeying 2 of certain calcium tablets at every turn, in fact you just obeyed should obey the calcium amount 10%! Some paediatrics doctors control Rickets when ineffective, think it is that calcium is not absorbed by mistake, turn to megavitamin D mistakenly so will treat emphasis.It is reported that somewhere vitamin D consumption competes to surpass tens of times of physiological requirements amounts, cause the surge of poisoning by vitamin D infant, this is a misunderstanding unprecedented on the medicament history! So, what is calcium on earth? calcium is to enliven one of element in the human body most.In people's body, safeguard during the calcium metabolism balance that the life and health integral level plays an important role, we can say calcium be human body life this.Except C (carbon), H (hydrogen), O (oxygen), N (nitrogen), Ca (calcium) are the maximum inorganic elements of content in the human body, and calcium is distributed in each position of human body whole body, from the bone to muscle, blood, from the cell membrane to cytoplasm, nucleus, calcium be do not have do not deposit.Modern practice proves, calcium all plays an important role to keeping normal functions such as circulation in each system of human body, breathing, nerve, digestion, endocrine, muscle, bone, uropoiesis, immunity.Pregnant woman's calcium deficiency is unfavorable for that the calcium in the fetus body accumulates, bone calcification and tooth form, and also can cause diseases such as the pregnant woman twitches, pregnant high disease; The long-term calcium deficiency of children is suffered from diseases such as rickets, night sweat, convulsions easily, and influence is grown; Teenager's calcium deficiency can cause bone growth bad; The elderly's calcium deficiency can cause the minimizing of bone calcium, blood calcium to increase, and is prone to diseases such as osteoporosis, osteoproliferation, hypertension, diabetes, artery sclerosis, senile dementia.The modern medicine practice is taken off out: the disease hypertension that the contemporary death rate is the highest, diabetes, heart disease just have important relationship with long-term calcium deficiency.Because calcium plays an important role to health, industrially developed country attaches great importance to national demand to calcium nutrition.U.S. sanitary mechanism proposes the adult should absorb calcareous 800 milligrams every day, and pregnant woman, wet nurse and the elderly individually should be lower than 1500 milligrams.It also is 800 milligrams that China's trophic level requires the adult to take in the calcium amount every day, yet actual intake differs greatly.Data according to Chinese nutrition generaI investigation show: nineteen eighty-two per capita calcium intake only be the 520mg/ day for human beings, the pay standard from the 800mg/ day for human beings differs the 280mg/ day for human beings, compliance rate only is 71.3%.The calcium deficiency rate is 27.8%.See that with regard to average national level the weary disease of calcium deficiency has become China people common, the most serious current nutrition problem.From different crowd's classification situations, Chinese children, teenager, women and old man's calcium deficiency phenomenon are more outstanding.More alarming is that this situation still is in the development trend of continuous deterioration.From 1987 nineteen sixties 27 in the period of, Beijing's nurseries and kindergartens children calcium nutrition intake has descended 30.3%.1995-1989, China cooperates with the United Nations Children's Fund, and seven province poverty-stricken area preschool child's nutritional surveillance results are shown: local children calcium nutrition compliance rate is generally at 20%-30%.China women, especially pregnant woman's situation is serious equally.Beijing carried out the diet nutritional monitoring in 1986,1,987 two to the normal pregnancies of Beijing hospital for gynaecology and obstetrics, found that the calcium deficiency number is 100% of a monitoring target among the pregnant woman in late period.Even Pekinese's situation is like this, well imagine in other city.Calcium deficiency is the common issue with that the whole world faces, and replenishing the calcium then is medical circle, a nutrition educational circles difficult problem of generally acknowledging for a long time, and traditional calcium preparation has little effect to solving modern calcium deficiency phenomenon owing to be difficult to be absorbed by the body and utilize and exist other problem.Since the eighties, both at home and abroad the research of calcium nutrition is done a lot of work, Beijing refreshing calcium activated difficult to understand factory takes the lead in having proposed in nutrition educational circles " mankind replenish the calcium engineering " new ideas, and combines with traditional product from science and technology and to start with, and has developed high-tech new calcium nutrition special efficacy tonic-Ao god board calcium activated.Their aim is exactly with the achievement of modern science and technology to the research of calcium nutrition special efficacy, pushes the enforcement action of concrete protection health to, pushes the production application of calcium nutrition special efficacy tonic to from the consciousness of replenishing the calcium.Calcium has two kinds of forms to exist in human body, and a kind of is in conjunction with phosphoric acid in calcium such as the bone salts and calcium carbonate, and another kind is a free calcium, is present in the middle of blood and the soft tissue with ionic condition.Calcium activated just is meant free calcium, and is active because of its chemical property, easily is absorbed by the body to utilize and gain the name, and it is member up-to-date in the calcium family.Contain the trace element that needed by human body is wanted in the calcium activated,, health is had important function as tens kinds of trace elements such as calcium oxide, potassium oxide, sodium oxide molybdena, ionized calcium, iron, manganese, copper, zinc, magnesium.Each developing country is is all researching and producing calcium activated now, to solve the problem of human calcium deficiency.
The object of the present invention is to provide a kind of nutrient solution that contains calcium activated, this nutrient solution is by taking the needs that the formulation difference satisfies the crowd, rapidly ionization and being absorbed in vivo after being characterized in taking, effect is quick, can not need to take simultaneously acceptance conditions such as VD, solar radiation.These series of products are the calcium ion content height not only, contains simultaneously to plant trace element and ten several amino acids vitamins etc. surplus the magnesium (Mg), zinc (Zn), manganese (Mn), silicon (Si), phosphorus (P), iron (Fe), sodium (Na), potassium (K) etc. ten of needed by human body.In addition, it makes solid-state calcium activated originally, on the basis that keeps original nutritive value, is converted into liquid calcium, is beneficial to children's torso and absorbs.The activated calcium powder that calcium content is abundant is made calcium ion water soluble in water, and this high-quality drinking water does not contain hazardous substance, and mineral matter is more suitable, and being ionic condition, pH value belongs to alkalescent, the dissolved oxygen amount height, hydrone group little (dissolubility, penetration strong), can remove body inner acidic metabolin and poisonous substance, be next half a lifetime discipline people's main drinking water, in a large amount of the use, abundant experimental data shows, all products that it is related to the human body calcium deficiency all have no side effect, and are safe and reliable.
The nutrient solution that contains calcium activated provided by the present invention is wherein formed and is comprised calcium activated, sucrose, honey, haw juice, jujube juice, potassium sorbate, distilled water.
The nutrient solution that contains calcium activated provided by the present invention, wherein form proportioning and be:
Form proportioning (parts by weight are represented):
Calcium activated 0.20-0.56 part (in element calcium);
Sucrose is an amount of;
Honey 100-300 part;
Haw juice 100-300 part;
Jujube juice 50-250 part;
1 part of potassium sorbate;
Distilled water adds to the 800-1500 milliliter.
The nutrient solution that contains calcium activated provided by the present invention, wherein form proportioning and be:
Form proportioning (parts by weight are represented):
0.33 part of calcium activated (in element calcium);
Sucrose is an amount of;
150 parts of honey;
100 parts of haw juices;
100 parts of jujube juices;
1 part of potassium sorbate;
Distilled water adds to 1000 milliliters.
The nutrient solution that contains calcium activated provided by the present invention, wherein production process comprises: calcium activated is water-soluble; Sucrose is water-soluble; With calcium activated water, sucrose water and honey, haw juice, date juice mix, and heating was boiled 2 hours, added potassium sorbate, and stirring and dissolving is filtered, and adds boiled-out water and supplies quantity, and every bottle of packing is sealed, packing.
The preparation method of one of wherein related component calcium activated is: with oyster or birds, beasts and eggs shell is that raw material makes through high-temperature calcination or acetic acid activation.
Wherein selected oyster can be the left shell of deep-sea, Dalian oyster more than 50 years;
Wherein said high-temperature calcination be with oyster or birds, beasts and eggs shell in 800-3600 ℃ of following calcination 4-12 hour, be crushed to the 250-600 order then.
It is earlier oyster or birds, beasts and eggs shell to be pulverized that wherein said acetic acid soaks activation process, then with acetic acid and oyster or birds, beasts and eggs shell by 350-500 part: 100 parts of ratios mixing, 60-180 ℃ of immersion 2-6 hour, in small, broken bits again after the drying to the 250-600 order.
The main calcic of calcium activated by above technology preparation also contains other micro elements, and calcium (Ca) content should be 46.0~53.0%.The proterties of this product is a white powder, odorless, the flavor salty slightly, puckery; This product is dissolved in acid; Each testing result shows:
(discriminating) gets this product, adds water and makes saturated solution, filters, and filtrate shows the identification (27 pages of appendix of Chinese Pharmacopoeia nineteen ninety version) of calcium salt.
(inspection) basicity is got this product 1.5g, show in the 500ml measuring bottle, it was an amount of to add water, in 15-25 ℃ of jolting 20 minutes, thin up is to scale, mixing filters, and discards filtrate just, precision is measured subsequent filtrate in conical flask, add 1 of instructions phenolphthalein solution, to colourless, consuming hydrochloric acid solution (0.1mol/L) must not surpass with hydrochloric acid solution (0.1mol/L) volumetric soiutions.
Heavy metal is got this product 0.5g, after adding water 3ml and stirring evenly, slowly add watery hydrochloric acid 10ml, boiled 5 minutes, put cold, filtration, filter washs with low amounts of water, merge washing lotion and filtrate, add 1 of instructions phenolphthalein solution, and drip ammonia solution to the apparent pink of solution, after adding acetate buffer (PH3.5) 2ml, thin up becomes 25ml, checks (42 page of first method of appendix of 1990 versions of Chinese Pharmacopoeia) in accordance with the law, and the content metal must not cross 30/1000000ths.
(assay) gets the about 0.1g of this product, and accurate the title decides, and adds watery hydrochloric acid 10ml, after the dissolving, adds water 10ml, and 1 of the red indicator solution of methylate drips ammonia solution and makes solution become little yellow by redness, adds 20% triethanolamine solution 5ml, shakes up; Other is the 10ml that fetches water, ammonification monochlor(in)ate ammonium buffer solution (PH10.0) 10ml, 1 of dilute sulfuric acid magnesium test solution and eriochrome black T indicator solution a little (0.05mol/L), drip Calcium Disodium Versenate liquid to solution and show pure blue, in the above-mentioned solution of this solution impouring, fixed with the Calcium Disodium Versenate drop, during nearly terminal point, add the black T indicator of network a little, continue titration to solution and change pure blue into, promptly from aubergine.Every EDTA two is received liquid (0.05mol/L) and is equivalent to the Ca of 2.004mg.
Pharmacological action:
Nutrient solution provided by the present invention has chemism and physical activity calcium ion, is the natural materials that has activated, and very easily is absorbed by the body, and contains other trace element of necessary for human body.The major part of these elements is to have the enzyme system of physiological function and the key component of protein system, and to the nucleic acid solution element, cell membrane plays stable or activation.
Toxic and side effect:
Nutrient solution provided by the present invention has no side effect, LD 50Be 6.95 ± 1.80g/kg.
Function:
Nutrient solution provided by the present invention helps sclerotin to form, and safeguards nerve conduction and contraction of muscle, keeps the normal osmotic pressure of capillary, keeps blood acid-base balance etc.,
Indication:
1, acute blood calcium deficiency disease; As infantile tetany, adult's subthyroidism and the tetany disease that causes.
2, children's's rickets, senile osteoporosis, bone is painful, osteoproliferation.
3, climacteric is comprehensively descended disease, the inadaptation that pregnant and lying-in women rise because of calcium deficiency.
4, nettle rash, eczema, angioneurotic edema, allergic symptoms such as pruitus.
5, prevent and treat chronic acalcicosis, cardiovascular, diabetes, the low calcium hypertension of primary etc.
Nutrient solution provided by the present invention is to be primary raw material with the natural marine organism, produces through special processing technology.How tame authoritative mechanism is detected through the whole nation, and every technical indicator all meets or exceeds GB9990-88 (notes) standard and regulation, is a kind of brand-new special efficacy calcium nutritional supplement.It has overcome existing calcium agent center must be aided with disadvantages such as vitamin D, cod-liver oil, solar radiation, very easily dissolving, very easily absorption, calcium content reaches more than 60%, can adjust the balance of human osteocalcin, blood calcium and intracellular Ca2+, reduce the blood viscousness degree, reconcile nerve center, endocrine, microcirculation function, improve immune function of human body, eyesight improving and brain strengthening is arranged, protect the liver kidney-nourishing, activate blood circulation and disperse blood clots, the effect of anti-senility.The diabetes that the elderly's calcium deficiency is caused, hypertension, angiocardiopathy, osteoporosis, osteoproliferation, muscle cramp, illness such as numb in every limb all have rehabilitation efficacy preferably.
The nutrition product standard that contains calcium activated provided by the present invention is:
1, organoleptic indicator: be weak yellow liquid, the bright fragrance of fruit arranged, the sweet acid of distinguishing the flavor of, puckery slightly, free from extraneous odour.
2, outward appearance: cleaning, pollution-free, seal tightly, it is clear that label is rectified.
3, physical and chemical index:
Calcium activated: every bottle contains calcium activated (in element calcium) and should be 10mg ± 2mg.
Pol: 10 ± 2 °
Device difference: 30ml ± 3ml
4, hygiene index:
Total number of bacteria/ml:<100
Escherichia coli/100ml:<3
Pathogenic bacteria: must not detect
The method of inspection:
1, sense index: range estimation, tasting should be up to specification
2, outward appearance: range estimation should be up to specification
3, calcium activated: according to (GB9990-88)
Sample thief 50ml adds watery hydrochloric acid 5ml, tartarize amine 2.5ml, triethanolamine 5ml adds 20% NaOH 10ml, potassium cyanide 5ml again behind the mixing, calred indicator 0.2g becomes pure blue with 0.02M disodium ethylene diamine tetraacetate titer titration to solution by claret.
Every bottle contains Ca (mg)=MV * 40.08/50 * 30
4, pol: measure with saccharometer
5, content uniformity: get 5 bottles of metered volume, must not have above device difference limit.
Embodiment 1
Select the left shell of deep-sea, Dalian oyster more than 50 years for use,, be crushed to 400 orders then and obtain the calcium activated powder its 2000 ℃ following calcination 8 hours, take by weighing 0.33 part of calcium activated (in element calcium) then, sucrose is an amount of, 150 parts of honey, 100 parts of haw juices, 100 parts of jujube juices, 1 part of potassium sorbate, calcium activated is water-soluble, and sucrose is water-soluble, with calcium activated water, sucrose water and honey, haw juice, date juice mix, and heating was boiled 2 hours, add potassium sorbate, stirring and dissolving, filter, add boiled-out water and complement to 1000 milliliters, every bottle of packing, seal packing.

Claims (8)

1, a kind of nutrient solution that contains calcium activated is wherein formed and is comprised calcium activated, sucrose, honey, haw juice, jujube juice, potassium sorbate, distilled water.
2, the described nutrient solution that contains calcium activated of claim 1, wherein form proportioning and be:
Form proportioning (parts by weight are represented):
Calcium activated 0.20-0.56 part (in element calcium);
Sucrose is an amount of;
Honey 100-300 part;
Haw juice 100-300 part;
Jujube juice 50-250 part;
1 part of potassium sorbate;
Distilled water adds to the 800-1500 milliliter.
3, the described nutrient solution that contains calcium activated of claim 1, wherein form proportioning and be:
Form proportioning (parts by weight are represented):
0.33 part of calcium activated (in element calcium);
Sucrose is an amount of;
150 parts of honey;
100 parts of haw juices;
100 parts of jujube juices;
1 part of potassium sorbate;
Distilled water adds to 1000 milliliters.
4, the described nutrient solution that contains calcium activated of claim 1, wherein production process comprises: calcium activated is water-soluble; Sucrose is water-soluble; With calcium activated water, sucrose water and honey, haw juice, date juice mix, and heating was boiled 2 hours, added potassium sorbate, and stirring and dissolving is filtered, and adds boiled-out water and supplies quantity, and every bottle of packing is sealed, packing.
5, the described nutrient solution that contains calcium activated of claim 1, wherein said calcium activated prepares by the following method: with oyster or birds, beasts and eggs shell is that raw material makes through high-temperature calcination or acetic acid activation.
6, the described nutrient solution that contains calcium activated of claim 5, wherein said oyster is the left shell of deep-sea, Dalian oyster more than 50 years.
7, the described nutrient solution that contains calcium activated of claim 5, wherein said high-temperature calcination be with oyster or birds, beasts and eggs shell in 800-3600 ℃ of following calcination 4-12 hour, be crushed to the 250-600 order then.
8, the described nutrient solution that contains calcium activated of claim 5, it is earlier oyster or birds, beasts and eggs shell to be pulverized that wherein said acetic acid soaks activation process, then with acetic acid and oyster or birds, beasts and eggs shell in 350-500 part: 100 parts of ratios are mixed, soaked 2-6 hour at 60-180 ℃, in small, broken bits again after the drying to the 250-600 order.
CN96120439A 1996-10-31 1996-10-31 Nutritus liquid containing active calcium Pending CN1181205A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100345502C (en) * 2005-03-25 2007-10-31 李理 Novel method for preparing composite organic calcium with high water solubility by using acid fruit juice and eggshell
CN103837531A (en) * 2014-03-25 2014-06-04 黑龙江八一农垦大学 Reagent for detecting blood calcium of milk in semi-quantitative way
CN103859421A (en) * 2014-03-03 2014-06-18 四川华通柠檬有限公司 Preparation method of liquid calcium citrate malate, liquid calcium citrate malate oral solution and preparation methods thereof
CN104055186A (en) * 2014-07-09 2014-09-24 舒文一 Processing method and product of ionized calcium solid drink

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100345502C (en) * 2005-03-25 2007-10-31 李理 Novel method for preparing composite organic calcium with high water solubility by using acid fruit juice and eggshell
CN103859421A (en) * 2014-03-03 2014-06-18 四川华通柠檬有限公司 Preparation method of liquid calcium citrate malate, liquid calcium citrate malate oral solution and preparation methods thereof
CN103859421B (en) * 2014-03-03 2016-01-06 四川华通柠檬有限公司 Liquid lemon calcium citrate malate preparation method, lemon tartaric acid Ca oral liquid and preparation method
CN103837531A (en) * 2014-03-25 2014-06-04 黑龙江八一农垦大学 Reagent for detecting blood calcium of milk in semi-quantitative way
CN104055186A (en) * 2014-07-09 2014-09-24 舒文一 Processing method and product of ionized calcium solid drink

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