CN117899212A - 用于治疗癌症的瑞格菲尼和pd-1/pd-l1(2)抑制剂的组合产品 - Google Patents
用于治疗癌症的瑞格菲尼和pd-1/pd-l1(2)抑制剂的组合产品 Download PDFInfo
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- CN117899212A CN117899212A CN202410088226.5A CN202410088226A CN117899212A CN 117899212 A CN117899212 A CN 117899212A CN 202410088226 A CN202410088226 A CN 202410088226A CN 117899212 A CN117899212 A CN 117899212A
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Classifications
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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Landscapes
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
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| EP17174169 | 2017-06-02 | ||
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| CN201880036504.5A CN110662540B (zh) | 2017-06-02 | 2018-05-25 | 用于治疗癌症的瑞格菲尼和pd-1/pd-l1(2)抑制剂的组合产品 |
| PCT/EP2018/063785 WO2018219807A1 (en) | 2017-06-02 | 2018-05-25 | Combination of regorafenib and pd-1/pd-l1(2) inhibitors for treating cancer |
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| CN202410088226.5A Pending CN117899212A (zh) | 2017-06-02 | 2018-05-25 | 用于治疗癌症的瑞格菲尼和pd-1/pd-l1(2)抑制剂的组合产品 |
| CN202311446796.9A Pending CN117582495A (zh) | 2017-06-02 | 2018-05-25 | 用于治疗癌症的瑞格菲尼和pd-1/pd-l1(2)抑制剂的组合产品 |
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| CN111001004A (zh) * | 2019-10-08 | 2020-04-14 | 广州医科大学附属第二医院 | 一种治疗肝癌的药物组合及其应用 |
| WO2025117638A1 (en) * | 2023-12-01 | 2025-06-05 | Yale University | Compositions and methods for treating cancer |
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| NZ544920A (en) | 2003-07-23 | 2009-11-27 | Bayer Healthcare Llc | 4{4-[3-(4-chloro-3-trifluoromethylphenyl)-ureido]-3-fluorophenoxy}-pyridine-2-carboxylic acid methylamide and metabolites for the treatment and prevention of diseases and conditions |
| KR20080074974A (ko) | 2005-11-10 | 2008-08-13 | 바이엘 헬스케어 아게 | 당뇨병성 신경병증을 치료하기 위한 디아릴 우레아 |
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