CN117837664A - A tablet candy for relieving hangover and protecting liver, and its preparation method - Google Patents

A tablet candy for relieving hangover and protecting liver, and its preparation method Download PDF

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Publication number
CN117837664A
CN117837664A CN202310398560.6A CN202310398560A CN117837664A CN 117837664 A CN117837664 A CN 117837664A CN 202310398560 A CN202310398560 A CN 202310398560A CN 117837664 A CN117837664 A CN 117837664A
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protecting
liver
parts
powder
alcohol
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隋新兵
张明明
项煜
吴其标
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Abstract

The invention relates to the technical field of health-care food, in particular to an anti-alcohol liver-protecting tabletting candy and a preparation method thereof, wherein the anti-alcohol liver-protecting tabletting candy comprises the following raw materials in parts by weight: 0.5 to 5 parts of kudzuvine root, 0.5 to 5 parts of turmeric, 0.5 to 5 parts of hovenia dulcis thunb, 0.5 to 1 part of tea polyphenol, 13 to 22 parts of corn oligopeptide, 0.05 to 0.3 part of ammonium glycyrrhizate, 15 to 25 parts of maltodextrin, 10 to 20 parts of glucose and 30 to 50 parts of xylitol. The raw materials of the anti-alcoholic liver-protecting tabletting candy are matched according to a scientific method, the anti-alcoholic liver-protecting tabletting candy is safe and reliable, the raw materials complement each other, the active ingredients are in synergistic effect, the metabolism of alcohol in a human body can be accelerated, the effects of anti-alcoholic liver-protecting can be achieved, the anti-alcoholic liver-protecting targeting is high, and the anti-alcoholic liver-protecting tabletting candy is convenient to carry and eat in a tabletting candy form, and is very friendly to health of drinkers due to simple components and obvious effects.

Description

A tablet candy for relieving hangover and protecting liver, and its preparation method
Technical Field
The invention relates to the technical field of health-care foods, in particular to a tablet candy for dispelling the effects of alcohol and protecting the liver and a preparation method thereof.
Background
Drinking is a living habit of many people, and proper drinking has certain benefits to the body, such as proper drinking can activate blood, remove meridian obstruction, remove cold, eliminate fatigue, tension state and the like, but excessive drinking is harmful and not beneficial because alcohol can generate a lot of substances which are unfavorable to the health of the human body in the metabolic process of the human body, such as generating acetaldehyde with cancerogenic action, free radicals which can cause peroxidation of lipid, DNA, protein and the like. Along with the improvement of living standard and the continuous increase of social pressure, the proportion of drinking people in China is also continuously rising. In daily life, people often drink excessive amounts of alcohol due to work needs, and sometimes drunk to cause discomfort, unconsciousness of the brain, and even serious health problems caused by excessive drinking of partial alcohol addicts, such as alcoholic liver disease is the most common organ damage caused by ethanol.
Since wine culture is popular in Chinese food culture, such as social consideration, family gathering, friends gathering, etc., the wine culture should be actively advocated to avoid alcoholism and care about the body before and after drinking in order to reduce the occurrence of alcohol-induced diseases and avoid liver injury. With the increasing importance of people on health, the public is increasingly concerned about the anti-alcoholic liver protection product and the demands on the anti-alcoholic liver protection product are gradually increased. Modern researches have shown that the traditional Chinese medicine has obvious therapeutic effect in the disease course of alcoholic liver disease, has a certain liver protection effect while rescuing alcoholism, and has the advantages of multiple target points treatment due to multiple effective components of the traditional Chinese medicine. However, the traditional Chinese medicine has a lot of medicinal herbs, more ingredients are a burden to the organism, and the medicine effect is not exact, so that the traditional Chinese medicine is not suitable for long-term administration. The medicinal and edible liver-strengthening and refreshing anti-alcoholic product can realize the organic combination of anti-alcoholic liver-protecting function and safety without toxic or side effect, is more in line with market and public demands, becomes the main direction of research and development of the current anti-alcoholic liver-protecting product, and has wide market prospect. However, although some current products adopt medicinal and edible materials or food materials, in order to increase the efficacy of the existing products, the added functional components are complex, the cost is increased, and the synergistic effect among the active components is weak, so that the overall effect of the products is general.
In the prior art, although various types of anti-alcoholic liver-protecting products serving as health-care foods have different functional effects, there are still many places to be improved, for example, drinks with anti-alcoholic effects generally have good effects of clearing heat and reducing pathogenic fire, protecting and nourishing liver, but the problems of a plurality of medicinal flavors, complex interaction, inconvenience in carrying and the like generally exist; in order to be convenient to carry about and eat, many products for dispelling effects of alcohol and protecting liver are processed into soft sweets, but as most of the components for solving the effect of protecting liver in the existing soft sweets for dispelling effects of alcohol and protecting liver are plant extracts, the components are added to make the soft sweets which are easy to return sand and to be melted, so that the quality of the soft sweets is reduced, the normal sales and eating of the soft sweets are influenced, and in order to increase the eating taste and quality of the soft sweets, more additives are usually added, and adverse effects are also caused to human bodies to a certain extent; in order to reduce the addition of the additive, accurately control the addition amount of the medicine, and have low cost and good effect, the tablet candy becomes an alternative. At present, the number of tabletting products is large, but the number of the existing tabletting products for dispelling the effects of alcohol is small, functional components added in the tabletting products are large, the actual effect is common, the complicated components are easy to cause burden on the body after being taken for a long time, the cost is increased, and the targeted effect of dispelling the effects of alcohol and protecting the liver is needed to be improved.
Disclosure of Invention
The invention provides a tablet candy for dispelling effects of alcohol and protecting liver and a preparation method thereof, which can exert remarkable effects of dispelling effects of alcohol and protecting liver by utilizing the synergistic effect among medicines, has the advantages of long-term taking by a parent price, and solves the problems of complex components, high cost, poor targeting effects of dispelling effects of alcohol and protecting liver and the like of tablet products for dispelling effects of alcohol and protecting liver in the prior art.
In order to achieve the aim of the invention, the invention is realized by the following technical scheme:
the invention provides a tablet candy for dispelling effects of alcohol and protecting liver, which comprises the following raw materials in parts by weight: 0.5 to 5 parts of kudzuvine root, 0.5 to 5 parts of turmeric, 0.5 to 5 parts of hovenia dulcis thunb, 0.5 to 1 part of tea polyphenol, 13 to 22 parts of corn oligopeptide, 0.05 to 0.3 part of ammonium glycyrrhizate, 15 to 25 parts of maltodextrin, 10 to 20 parts of glucose and 30 to 50 parts of xylitol.
Preferably, the anti-alcohol liver-protecting tabletting candy comprises the following raw materials in parts by weight: 1 to 3.5 parts of kudzuvine root, 1 to 4 parts of turmeric, 1 to 4 parts of hovenia dulcis thunb, 0.6 to 0.8 part of tea polyphenol, 15 to 19 parts of corn oligopeptide, 0.08 to 0.2 part of ammonium glycyrrhizate, 18 to 23 parts of maltodextrin, 13 to 17 parts of glucose and 36 to 40 parts of xylitol.
The radix puerariae in the formula of the invention is the dried root of Pueraria lobata (Willd.) Ohwi or Pueraria thomsonii Pueraria thomsonii benth of Leguminosae recorded in Chinese pharmacopoeia. Cool in nature, sweet and pungent in flavor. Relieving exterior syndrome and fever, promoting the production of body fluid, promoting eruption, ascending yang and relieving diarrhea. The "compendium of materia Medica" carries: pueraria lobata has the effects of clearing heat, reducing fire and expelling toxin, and is cool in nature, flat in nature and sweet in taste. Modern pharmaceutical research has shown that: the Pueraria lobata (Willd.) Ohwi contains abundant bioactive substances such as puerarin, xun Gensu glucoside, soybean isoflavone, daidzein, aminomethane acid, microelements, and triterpene substance alkali which are beneficial to human body. Has effects in nourishing, caring skin, resisting aging, improving osteoporosis, regulating estrogen level, scavenging waste, improving circulation, reducing blood lipid, reducing weight, and regulating blood pressure. In clinic, kudzuvine root is commonly used for dispelling the effects of alcohol, mainly because the kudzuvine root can enhance the regeneration capability of liver cells, promote the detoxification function of liver, and especially can effectively repair the injury of liver after drinking.
The turmeric in the formula of the invention is the dried rhizome of the turmeric of the family Zingiberaceae, namely the turmeric of the family Zingiberaceae, recorded in Chinese pharmacopoeia. Pungent and bitter in nature and warm in nature. Enter liver and spleen meridians. Promoting blood circulation, activating qi-flowing, dredging channels and relieving pain. Modern medical research has shown that: turmeric has various pharmacological effects of resisting myocardial ischemia, regulating lipid, resisting tumor, resisting pulmonary fibrosis, resisting tissue injury, regulating immunity, etc. Curcumin in turmeric can improve glutathione content in liver tissues, and the glutathione can decompose ethanol concentration in vivo and accelerate alcohol metabolism in vivo, so that certain anti-alcohol effect can be achieved.
The semen hoveniae in the formula of the invention is the ripe seeds of Hovenia dulcis Thunnb. Hovenia acerba Lindl. And Mao Guozhi Hovenia Hovenia trichocarpa Chun et Tsiang, which are the plants of Hovenia genus of Rhamnaceae and are recorded in Chinese pharmacopoeia. Fruits with flower axes are also useful. Sweet in nature and neutral in nature. Has effects of relieving alcoholism, quenching thirst, relieving restlessness, relieving vomit, and relieving constipation. Is mainly used for treating drunk, polydipsia, vomit and inconvenient urination. The semen Hoveniae is firstly loaded in Tang Dynasty pharmacopoeia, "Xin Xiu Ben Cao", yun Zhu Feng and Xiao Fu Ji. No mention is made of anti-alcohol. The food therapy herbal medicine of Tang Dynasty Meng firstly discovers the anti-alcohol effect of the arbor, namely the hovenia dulcis thunb. The "branches and leaves of the plum best" are recorded in the "compendium of materia medica", which can prevent vomiting and adverse rise of qi, relieve alcoholism and expel insect poison ". Modern pharmaceutical research has shown that: the semen hoveniae contains glucose, fructose, potassium nitrate, peroxidase and other components, and can remove excessive free radicals generated in a human body after drinking, and prevent the formation of lipid peroxide, so that the concentration of ethanol in blood is obviously reduced, the damage of the ethanol to liver tissues is reduced, and various diseases caused by various metabolic abnormalities due to alcoholism are avoided. In addition, hovenia dulcis thunb is also a health-care fruit for digesting excessive fat of human body, and can lose weight and strengthen body after being eaten frequently.
The tea polyphenol in the formula of the invention is the total name of polyphenols in tea, namely white amorphous powder, also known as antioxidant, vitamin polyphenol and anti-harynx, is a compound of polyhydroxy phenols in tea, is composed of more than 30 phenols, and the main components are catechin and derivatives thereof, which are main chemical components with health care function in tea. The tea polyphenol has various physiological activities such as antioxidation, radiation protection, aging resistance, blood lipid reduction, blood sugar reduction, bacteriostasis, enzyme inhibition and the like. The tea polyphenol has obvious control effects on the following diseases: reducing blood pressure, anticoagulation, reducing blood fat, obesity, preventing and treating cardiovascular diseases such as arteriosclerosis and thrombosis, reducing blood sugar, preventing and treating diabetes, sterilizing and resisting virus; preventing and treating gastrointestinal tract diseases, respiratory tract diseases, influenza diseases and the like; preventing and treating hepatitis, resisting aging and enhancing immunity; strengthening teeth, preventing and treating periodontitis, preventing dental caries, deodorizing, and removing toxic substances. Tea polyphenols can be used as auxiliary medicine and health medicine for patients with above diseases.
The corn oligopeptide in the formula is produced by taking corn protein powder as a raw material through processes of pulp mixing, protease enzymolysis, separation, filtration, spray drying and the like. The corn oligopeptide is a new resource product, and has various biological activities, such as antioxidation, antihypertensive, immunity enhancement, fatigue resistance, liver protection and the like. Animal and human experiments have found that corn oligopeptide has an important functional property which is different from other food oligopeptide, namely sobering-up effect, so as to protect liver. The corn oligopeptide contains rich alanine and leucine, can achieve the effects of sobering up and protecting liver, can promote the decomposition and metabolism of alcohol after drinking wine, can avoid serious damage of alcohol to liver tissues, and can accelerate the toxin expelling function of the liver.
The ammonium glycyrrhetate in the formula is a chemical substance, has strong effects of resisting inflammation, protecting liver cell membranes, improving liver functions, preventing and treating liver injury caused by various liver toxicity drugs, and the like, is in a dose-dependent relationship, is beneficial to liver functions, does not cause injury to the liver, and is not suitable for excessive dosage.
Maltodextrin in the formula of the invention is a polysaccharide used as a food additive. It is made from plant starch by partial hydrolysis, usually in the form of a white hygroscopic spray-dried powder. Maltodextrin comprises a chain unit of d-glucose linked to a variable length. The glucose units are predominantly linked to alpha (1.fwdarw.4) glycosidic linkages. Maltodextrin generally consists of a mixture of chains, the length of which varies between 3 and 17 glucose units. Maltodextrin contains a large amount of saccharides, vitamins and trace elements, especially trace elements and minerals such as calcium, iron and the like which are beneficial to human bodies, can promote normal metabolism and metabolism of the human bodies, and is suitable for being used as a basic food raw material and an additive of patients. If the patient cannot eat or ingest a small amount of glucose normally, a certain amount of maltodextrin can be added into the food, so that the blood sugar can be increased, the immunity and the resistance can be enhanced, and vitamins and trace elements can be supplemented. In addition, the maltodextrin has good solubility and dilutability and is easy to digest and absorb by human bodies, so that the maltodextrin can effectively supplement glucose and nutrition.
Glucose in the formula of the invention is an indispensable nutrient for metabolism in organisms. The glucose is easy to be absorbed in the alimentary canal and is directly utilized by human body after being absorbed in the process that the human body mainly participates in metabolism, so that the glucose can supplement water and sugar in the human body, supplement liquid to provide energy, supplement blood sugar, strengthen heart, induce urination and detoxify. Glucose can be combined with ethanol to play a role in dispelling effects of alcohol. Glucose also has diuretic effect, and can accelerate metabolism, promote food excretion through liver and kidney of human body, and alcohol drunk into stomach can be rapidly excreted in human body under the action of glucose, so as to realize alcohol knowing effect.
Xylitol in the formula of the invention is a normal intermediate product of xylose metabolism, and the pure xylitol is white crystals or white powdery crystals in appearance. Xylitol is widely found in natural world in foods such as fruits, vegetables, cereals, mushrooms, and plants such as wood, straw, corncob, and the like. It can be used as sweetener, nutrient and medicament in chemical industry, food, medicine, etc.
According to the invention, the characteristics of human skills are combined under the guidance of the theory of traditional Chinese medicine, the kudzuvine root, the turmeric and the hovenia dulcis thunb are selected for compatibility, and the dosage of each medicinal material is determined through the relation between the functional components, so that the components are synergistic. The prior experiments show that the kudzuvine root, the turmeric and the hovenia dulcis thunb are used together, the dosage is different or the medicinal materials in one of the medicines or the replacement formula are lack of the medicines, so that the effect of dispelling the effects of alcohol is large, the functions of dispelling the effects of alcohol and protecting liver can not be achieved, and the metabolism can be regulated, and the compatibility is better than that of a single medicine.
Radix Puerariae, curcuma rhizome, semen Hoveniae have been listed as anti-hangover special drugs in traditional Chinese medicine since ancient times. The kudzuvine root is good in dispersing and ventilating thoroughly, the turmeric and the hovenia dulcis thunb are capable of clearing heat and promoting urination, and dispersing damp turbidity can enable pathogenic qi of wine to be discharged out of the body, compatibility of the two medicines is mutually used, dispersion and seepage are combined, the effect of dispelling alcohol toxicity can be enhanced, the hovenia dulcis thunb is also capable of moistening five viscera, the property is mild, and the phenomenon that the kudzuvine root is excessively dispersed can be avoided. The tea polyphenol is matched, so that the activity of acetaldehyde dehydrogenase is enhanced, the alcohol metabolism is accelerated, meanwhile, the injury caused by livers is reduced to the greatest extent, and no tea polyphenol component is contained in the existing sobering-up medicines in the market. The ammonium glycyrrhetate is used for matching, so that the problem of liver injury repair after drinking can be solved, the injury of alcohol to the liver can be obviously reduced, and the injured liver can be recovered as soon as possible, which is also the efficacy which is not available in the prior art for sobering up. In addition, the corn oligopeptide, maltodextrin, glucose and xylitol in the formula are beneficial to promoting the decomposition and metabolism of alcohol by human bodies and protecting liver functions, and meanwhile, the addition of the maltodextrin and the xylitol can reduce the addition amount of the glucose and can be eaten by people incapable of normally taking the glucose.
Preferably, the anti-alcoholic liver-protecting tabletting candy further comprises the following auxiliary materials in parts by weight: 0.02-0.06 part of essence and 0.01-0.03 part of sucralose.
Preferably, the essence is peppermint powder or sweet orange powder.
The anti-alcohol liver-protecting tabletting candy provided by the invention has the advantages that the taste is improved, the medicine taste is weakened, the acceptance of people is improved, and the tabletting candy with two tastes, namely mint taste and sweet orange taste, is provided for meeting the requirements of people with different tastes, but is not limited to the two tastes.
A second object of the present invention is to provide a method for preparing the above-mentioned anti-hangover and liver-protecting tabletted candy, characterized by comprising the steps of:
(1) Weighing and proportioning: respectively weighing radix Puerariae powder, curcuma rhizome powder, semen Hoveniae powder, tea polyphenols, corn oligopeptide powder, ammonium glycyrrhizinate, maltodextrin and glucose;
(2) Granulating: mixing and granulating the weighed kudzuvine root powder, turmeric powder, hovenia dulcis thunb powder, tea polyphenol, corn oligopeptide powder, ammonium glycyrrhizate, maltodextrin and glucose to obtain a first mixture;
(3) And (3) drying: drying the first mixture obtained in the step (2) in a fluidized bed, and sieving to obtain mixture particles;
(4) Mixing: adding xylitol, essence and sucralose into the mixture particles obtained in the step (3), and uniformly mixing to obtain a second mixture;
(5) Tabletting: and (3) tabletting and sterilizing the second mixture obtained in the step (4) to obtain the anti-alcohol liver-protecting tabletting candy.
Preferably, the mixing granulation mode in the step (2) is wet mixing granulation.
Preferably, the number of the sieving meshes in the wet mixing granulation process is 16-22 meshes.
Preferably, the drying temperature in the step (3) is 45-60 ℃.
Preferably, the number of the screen meshes in the step (3) is 14 to 20 mesh.
Preferably, the water content of the mixture particles in the step (3) is 1 to 7%.
The invention has the following beneficial effects:
(1) The anti-alcoholic liver-protecting tablet candy has stronger pertinence for anti-alcoholic liver protection, can be used as an anti-alcoholic functional product after drunk, can also be used as a functional product for preventing drunk, and has good recuperation effect on drinkers;
(2) The raw materials of the anti-alcohol liver-protecting tabletting candy are matched according to a scientific method, are safe and reliable, supplement each other, and have the synergistic effect of the effective components, so that the metabolism of alcohol in a human body can be accelerated, the effects of anti-alcohol liver protection can be achieved, and the anti-alcohol liver-protecting candy has remarkable anti-alcohol liver-protecting effects;
(3) The anti-alcoholic liver-protecting tabletting candy disclosed by the invention is simple in preparation process, simple in raw materials, easy to obtain all components, low in cost, fragrant and sweet in taste, and almost free of toxic and side effects as health-care food, has no adverse effects at present, is capable of being used as a functional product with anti-alcoholic and liver-protecting effects, and is very friendly to health of drinkers due to simple components and obvious effects, and the anti-alcoholic liver-protecting tabletting candy is convenient to carry and eat in a tabletting candy form.
Drawings
Fig. 1 is a schematic diagram of the process flow for preparing the pressed candy of the present invention.
Detailed Description
The invention is further described below with reference to the drawings and specific examples. Those of ordinary skill in the art will be able to implement the invention based on these descriptions. In addition, the embodiments of the present invention referred to in the following description are typically only some, but not all, embodiments of the present invention. Therefore, all other embodiments, which can be made by one of ordinary skill in the art without undue burden, are intended to be within the scope of the present invention, based on the embodiments of the present invention.
Example 1
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 6.5g of kudzuvine root, 36g of turmeric, 65g of hovenia dulcis thunb, 8.4g of tea polyphenol, 208g of corn oligopeptide, 0.65g of ammonium glycyrrhizate, 260g of maltodextrin, 195g of glucose, 520g of xylitol, 0.26g of peppermint powder and 0.19g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy specifically comprises the following steps of:
(1) Weighing and proportioning: respectively weighing the radix puerariae powder, turmeric powder, semen hoveniae powder, tea polyphenol, corn oligopeptide powder, ammonium glycyrrhizate, maltodextrin and glucose according to the formula;
(2) Granulating: mixing the weighed radix Puerariae powder, curcuma rhizome powder, semen Hoveniae powder, tea polyphenols, corn oligopeptide powder, ammonium glycyrrhizinate, maltodextrin and glucose by wet method, granulating, adding purified water into the mixed powder, mixing and stirring to obtain soft material, kneading the soft material into clusters, and making into wet granule by 16 mesh screen;
(3) And (3) drying: drying the wet particles obtained in the step (2) in a fluidized bed at 50 ℃, and sieving the wet particles with a 14-mesh sieve to obtain mixture particles with water content of 5%;
(4) Mixing: adding xylitol, mint powder and sucralose with the formula amounts into the mixture particles obtained in the step (3), and uniformly mixing to obtain a second mixture;
(5) Tabletting: tabletting and sterilizing the second mixture obtained in the step (4) to obtain 1000 tablets, wherein the specification of the tablet is 1.3 g/tablet of the anti-alcohol liver-protecting tabletting candy.
Example 2
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 39g of kudzuvine root, 65g of turmeric, 39g of hovenia dulcis thunb, 6.5g of tea polyphenol, 215g of corn oligopeptide, 2.6g of ammonium glycyrrhizate, 255g of maltodextrin, 170g of glucose, 507g of xylitol, 0.53g of mint powder and 0.37g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Example 3
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 65g of kudzuvine root, 34.79g of turmeric, 6.5g of semen hoveniae, 8.9g of tea polyphenol, 169g of corn oligopeptide, 3.9g of ammonium glycyrrhizate, 195g of maltodextrin, 260g of glucose, 556g of xylitol, 0.78g of mint powder and 0.13g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Example 4
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 40g of kudzuvine root, 6.5g of turmeric, 40g of hovenia dulcis thunb, 13g of tea polyphenol, 286g of corn oligopeptide, 2.59g of ammonium glycyrrhizate, 276g of maltodextrin, 245g of glucose, 390g of xylitol, 0.52g of mint powder and 0.39g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Example 5
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 6.5g of kudzuvine root, 48g of turmeric, 48g of hovenia dulcis thunb, 7.8g of tea polyphenol, 222g of corn oligopeptide, 2.06g of ammonium glycyrrhizate, 325g of maltodextrin, 130g of glucose, 500g of xylitol, 0.46g of peppermint powder and 0.18g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Example 6
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 15g of kudzuvine root, 50g of turmeric, 29.29g of hovenia dulcis thunb, 8.5g of tea polyphenol, 183g of corn oligopeptide, 1.2g of ammonium glycyrrhizate, 212g of maltodextrin, 150g of glucose, 650g of xylitol, 0.70g of peppermint powder and 0.31g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Example 7
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 43g of turmeric, 39g of raisin tree seed, 9.1g of tea polyphenol, 221g of corn oligopeptide, 1.3g of ammonium glycyrrhizate, 260g of maltodextrin, 195g of glucose, 494g of xylitol, 0.52g of peppermint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Example 8
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 43g of turmeric, 39g of raisin tree seed, 9.1g of tea polyphenol, 221g of corn oligopeptide, 1.3g of ammonium glycyrrhizate, 260g of maltodextrin, 195g of glucose, 494g of xylitol, 0.52g of peppermint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy specifically comprises the following steps of:
(1) Weighing and proportioning: respectively weighing the radix puerariae powder, turmeric powder, semen hoveniae powder, tea polyphenol, corn oligopeptide powder, ammonium glycyrrhizate, maltodextrin and glucose according to the formula;
(2) Granulating: mixing the weighed radix Puerariae powder, curcuma rhizome powder, semen Hoveniae powder, tea polyphenols, corn oligopeptide powder, ammonium glycyrrhizinate, maltodextrin and glucose by wet method, granulating, adding purified water into the mixed powder, mixing and stirring to obtain soft material, kneading the soft material into clusters, and making into wet granule by sieving with 18 mesh sieve;
(3) And (3) drying: drying the wet particles obtained in the step (2) at 45 ℃ in a fluidized bed, and sieving the wet particles with a 16-mesh sieve to obtain mixture particles with the water content of 7%;
(4) Mixing: adding xylitol, mint powder and sucralose with the formula amounts into the mixture particles obtained in the step (3), and uniformly mixing to obtain a second mixture;
(5) Tabletting: tabletting and sterilizing the second mixture obtained in the step (4) to obtain 1000 tablets, wherein the specification of the tablet is 1.3 g/tablet of the anti-alcohol liver-protecting tabletting candy.
Example 9
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 43g of turmeric, 39g of raisin tree seed, 9.1g of tea polyphenol, 221g of corn oligopeptide, 1.3g of ammonium glycyrrhizate, 260g of maltodextrin, 195g of glucose, 494g of xylitol, 0.52g of peppermint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy specifically comprises the following steps of:
(1) Weighing and proportioning: respectively weighing the radix puerariae powder, turmeric powder, semen hoveniae powder, tea polyphenol, corn oligopeptide powder, ammonium glycyrrhizate, maltodextrin and glucose according to the formula;
(2) Granulating: mixing the weighed radix Puerariae powder, curcuma rhizome powder, semen Hoveniae powder, tea polyphenols, corn oligopeptide powder, ammonium glycyrrhizinate, maltodextrin and glucose by wet method, granulating, adding purified water into the mixed powder, mixing and stirring to obtain soft material, kneading the soft material into clusters, and making into wet granule by sieving with 22 mesh sieve;
(3) And (3) drying: drying the wet particles obtained in the step (2) in a fluidized bed at 60 ℃, and sieving the wet particles with a 20-mesh sieve to obtain mixture particles with the water content of 1%;
(4) Mixing: adding xylitol, mint powder and sucralose with the formula amounts into the mixture particles obtained in the step (3), and uniformly mixing to obtain a second mixture;
(5) Tabletting: tabletting and sterilizing the second mixture obtained in the step (4) to obtain 1000 tablets, wherein the specification of the tablet is 1.3 g/tablet of the anti-alcohol liver-protecting tabletting candy.
Example 10
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 43g of turmeric, 39g of hovenia dulcis thunb, 9.1g of tea polyphenol, 221g of corn oligopeptide, 1.3g of ammonium glycyrrhizate, 260g of maltodextrin, 195g of glucose, 494g of xylitol, 0.52g of sweet orange powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Comparative example 1
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 4g of turmeric, 39g of hovenia dulcis thunb, 9.1g of tea polyphenol, 230g of corn oligopeptide, 1.3g of ammonium glycyrrhizate, 260g of maltodextrin, 225g of glucose, 494g of xylitol, 0.52g of peppermint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Comparative example 2
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 43g of turmeric, 75g of hovenia dulcis thunb, 9.1g of tea polyphenol, 221g of corn oligopeptide, 1.3g of ammonium glycyrrhizate, 260g of maltodextrin, 195g of glucose, 458g of xylitol, 0.52g of peppermint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Comparative example 3
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 43g of turmeric, 9.1g of tea polyphenol, 260g of corn oligopeptide, 1.3g of ammonium glycyrrhizinate, 260g of maltodextrin, 195g of glucose, 494g of xylitol, 0.52g of peppermint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Comparative example 4
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 39g of hovenia dulcis thunb, 9.1g of tea polyphenol, 261g of corn oligopeptide, 1.3g of ammonium glycyrrhizate, 263g of maltodextrin, 195g of glucose, 494g of xylitol, 0.52g of mint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Comparative example 5
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 43g of turmeric, 39g of semen hoveniae, 9.1g of tea polyphenol, 251.78g of corn oligopeptide, 1.3g of ammonium glycyrrhizate, 260g of maltodextrin, 195g of glucose, 494g of xylitol, 0.52g of mint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Comparative example 6
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 43g of turmeric, 39g of hovenia dulcis thunb, 230.1g of corn oligopeptide, 1.3g of ammonium glycyrrhizate, 260g of maltodextrin, 195g of glucose, 494g of xylitol, 0.52g of peppermint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Comparative example 7
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 43g of turmeric, 39g of hovenia dulcis thunb, 9.1g of tea polyphenol, 221g of corn oligopeptide, 260g of maltodextrin, 196.3g of glucose, 494g of xylitol, 0.52g of peppermint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
Comparative example 8
A tablet candy for dispelling the effects of alcohol and protecting liver comprises the following raw materials in formula: 37.18g of kudzuvine root, 43g of turmeric, 39g of ginseng, 9.1g of tea polyphenol, 221g of corn oligopeptide, 1.3g of ammonium glycyrrhizate, 260g of maltodextrin, 195g of glucose, 494g of xylitol, 0.52g of peppermint powder and 0.26g of sucralose.
The preparation method of the anti-alcohol liver-protecting tabletting candy comprises the specific steps as in example 1.
[ Effect experiment ]
To further examine the anti-hangover effect of the anti-hangover liver-protecting tabletted candy of the present invention, 10 adult male volunteers were selected for the test, of which 3 adult male volunteers took the anti-hangover liver-protecting tabletted candy of example 7 before drinking and 6 adult male volunteers took the tabletted products of comparative examples 5 to 7 before drinking according to the eating method. 1 adult male volunteer took the anti-hangover agent before drinking according to the eating method. All the test persons drink the same wine (same mountain burned 53 °), and the specific test contents and results are shown in table 2.
Table 2 content and results of the anti-hangover effect test for 10 adult male volunteers
As can be seen from the experimental data in Table 2, the drinking amount of adult male volunteers taking the anti-hangover and liver-protecting candy in example 7 is obviously improved, and the anti-hangover time is substantially shortened by half compared with the case of not taking the anti-hangover and liver-protecting candy in example 7; the drinking amount and the anti-hangover time of adult male volunteers taking the tablet products in comparative examples 5 to 7 are not greatly changed, which indicates that the anti-hangover effect is greatly reduced if a certain ingredient in the formula is absent; as can be seen from the comparison of the drinking performance of the adult male volunteers taking the anti-hangover and liver-protecting candy in example 7 with the drinking performance of the adult male volunteers taking the anti-hangover, the anti-hangover and liver-protecting candy of the invention has a significantly higher anti-hangover effect than the commercially available anti-hangover products.

Claims (10)

1. The anti-alcohol liver-protecting tabletting candy is characterized by comprising the following raw materials in parts by weight: 0.5 to 5 parts of kudzuvine root, 0.5 to 5 parts of turmeric, 0.5 to 5 parts of hovenia dulcis thunb, 0.5 to 1 part of tea polyphenol, 13 to 22 parts of corn oligopeptide, 0.05 to 0.3 part of ammonium glycyrrhizate, 15 to 25 parts of maltodextrin, 10 to 20 parts of glucose and 30 to 50 parts of xylitol.
2. The anti-alcohol liver-protecting pressed candy as claimed in claim 1, which is characterized by comprising the following raw materials in parts by weight: 1 to 3.5 parts of kudzuvine root, 1 to 4 parts of turmeric, 1 to 4 parts of hovenia dulcis thunb, 0.6 to 0.8 part of tea polyphenol, 15 to 19 parts of corn oligopeptide, 0.08 to 0.2 part of ammonium glycyrrhizate, 18 to 23 parts of maltodextrin, 13 to 17 parts of glucose and 36 to 40 parts of xylitol.
3. The anti-alcohol liver-protecting tabletting candy according to claim 1 or 2, further comprising the following auxiliary materials in parts by weight: 0.02-0.06 part of essence and 0.01-0.03 part of sucralose.
4. A de-alcoholic liver-protecting tableting candy according to claim 3, wherein the flavour comprises peppermint powder or orange powder.
5. A process for preparing the anti-hangover liver-protecting tableting candy according to any one of claims 1 to 4, characterized by comprising the steps of:
(1) Weighing and proportioning: respectively weighing radix Puerariae powder, curcuma rhizome powder, semen Hoveniae powder, tea polyphenols, corn oligopeptide powder, ammonium glycyrrhizinate, maltodextrin and glucose;
(2) Granulating: mixing and granulating the weighed kudzuvine root powder, turmeric powder, hovenia dulcis thunb powder, tea polyphenol, corn oligopeptide powder, ammonium glycyrrhizate, maltodextrin and glucose to obtain a first mixture;
(3) And (3) drying: drying the first mixture obtained in the step (2) in a fluidized bed, and sieving to obtain mixture particles;
(4) Mixing: adding xylitol, essence and sucralose into the mixture particles obtained in the step (3), and uniformly mixing to obtain a second mixture;
(5) Tabletting: and (3) tabletting and sterilizing the second mixture obtained in the step (4) to obtain the anti-alcohol liver-protecting tabletting candy.
6. The method for preparing an anti-hangover and liver-protecting tableting candy according to claim 5, wherein the mixing granulation in the step (2) is wet mixing granulation.
7. The method for preparing an anti-hangover and liver-protecting tableting candy according to claim 6, wherein the mesh number of the sieves in the wet mixing granulation process is 16-22 mesh.
8. The method for preparing an anti-hangover and liver-protecting tabletted candy according to claim 5, wherein the drying temperature in the step (3) is 45-60 ℃.
9. The method for producing an anti-hangover and liver-protecting tabletted candy according to claim 5 or 8, wherein the mesh size of the screen in step (3) is 14 to 20 mesh.
10. The method for producing an anti-hangover and liver-protecting tableting candy according to claim 5, wherein the water content of the mixture particles in step (3) is 1 to 7%.
CN202310398560.6A 2023-04-14 2023-04-14 A tablet candy for relieving hangover and protecting liver, and its preparation method Pending CN117837664A (en)

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