CN117580941A - 多重CRISPR/Cas9介导的靶基因激活系统 - Google Patents

多重CRISPR/Cas9介导的靶基因激活系统 Download PDF

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Publication number
CN117580941A
CN117580941A CN202280046611.2A CN202280046611A CN117580941A CN 117580941 A CN117580941 A CN 117580941A CN 202280046611 A CN202280046611 A CN 202280046611A CN 117580941 A CN117580941 A CN 117580941A
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nucleic acid
seq
sequence
modified
encoding
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Chinese (zh)
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贝尔蒙特 J·C·伊兹皮苏亚
王超
廖信凱
P·雷迪
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Salk Institute for Biological Studies
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Salk Institute for Biological Studies
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    • C12N2310/00—Structure or type of the nucleic acid
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CN202280046611.2A 2021-04-28 2022-04-28 多重CRISPR/Cas9介导的靶基因激活系统 Pending CN117580941A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163181059P 2021-04-28 2021-04-28
US63/181,059 2021-04-28
PCT/US2022/026805 WO2022232442A2 (en) 2021-04-28 2022-04-28 Multiplex crispr/cas9-mediated target gene activation system

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CN117580941A true CN117580941A (zh) 2024-02-20

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US (1) US20240209354A1 (https=)
EP (1) EP4330375A4 (https=)
JP (1) JP2024515827A (https=)
CN (1) CN117580941A (https=)
AU (1) AU2022267320A1 (https=)
CA (1) CA3218209A1 (https=)
WO (1) WO2022232442A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119020323A (zh) * 2024-09-29 2024-11-26 中国农业科学院作物科学研究所 一种融合外切酶的CRIPSR/Cas12i3小麦基因编辑体系

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025111340A1 (en) * 2023-11-20 2025-05-30 William Marsh Rice University Engineered extrachromosomal nucleic acids and methods of use thereof
WO2025227064A1 (en) * 2024-04-26 2025-10-30 Renasci Biotechnologies, Inc. Genomic editing methods to treat cardiovascular disease, and compositions for use in practicing the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6793547B2 (ja) * 2013-12-12 2020-12-02 ザ・ブロード・インスティテュート・インコーポレイテッド 最適化機能ＣＲＩＳＰＲ−Ｃａｓ系による配列操作のための系、方法および組成物
AU2017219605B2 (en) * 2016-02-15 2023-04-13 Temple University - Of The Commonwealth System Of Higher Education Excision of retroviral nucleic acid sequences
AU2018393050A1 (en) * 2017-12-21 2020-06-18 Bayer Healthcare Llc Materials and methods for treatment of Usher Syndrome Type 2A
WO2019236081A1 (en) * 2018-06-06 2019-12-12 Salk Institute For Biological Studies Targeted gene activation using modified guide rna
EP4028063A1 (en) * 2019-09-13 2022-07-20 Regeneron Pharmaceuticals, Inc. Transcription modulation in animals using crispr/cas systems delivered by lipid nanoparticles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119020323A (zh) * 2024-09-29 2024-11-26 中国农业科学院作物科学研究所 一种融合外切酶的CRIPSR/Cas12i3小麦基因编辑体系

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WO2022232442A3 (en) 2022-12-15
AU2022267320A9 (en) 2023-11-30
EP4330375A2 (en) 2024-03-06
WO2022232442A2 (en) 2022-11-03
US20240209354A1 (en) 2024-06-27
AU2022267320A1 (en) 2023-11-23
JP2024515827A (ja) 2024-04-10
CA3218209A1 (en) 2022-11-03
EP4330375A4 (en) 2025-08-13

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