CN117562848A - Soothing and repairing essence and preparation method thereof - Google Patents
Soothing and repairing essence and preparation method thereof Download PDFInfo
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- CN117562848A CN117562848A CN202311688183.6A CN202311688183A CN117562848A CN 117562848 A CN117562848 A CN 117562848A CN 202311688183 A CN202311688183 A CN 202311688183A CN 117562848 A CN117562848 A CN 117562848A
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- 239000000203 mixture Substances 0.000 claims abstract description 26
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 24
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 23
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 claims abstract description 22
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- BQMNFPBUAQPINY-UHFFFAOYSA-N azane;2-methyl-2-(prop-2-enoylamino)propane-1-sulfonic acid Chemical compound [NH4+].[O-]S(=O)(=O)CC(C)(C)NC(=O)C=C BQMNFPBUAQPINY-UHFFFAOYSA-N 0.000 claims description 6
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- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention belongs to the field of skin care products, and discloses a soothing and repairing essence and a preparation method thereof. The essence comprises the following components: a component: polyhydric alcohol, EDTA-2Na, a thickener and water; and the component B comprises the following components: emulsifying agent, phytosterol, squalane, hydrogenated phosphatidylcholine and butanediol; and C, component: antioxidants, butylene glycol, humectants, water; and D, component: 1, 2-hexanediol, glycerol glucoside, fibronectin, anoectochilus roxburghii extract, and citric acid. The preparation method comprises the following steps: adding polyalcohol, EDTA-2Na and a thickening agent into water, and dissolving to prepare a mixture A; mixing phytosterol, squalane, hydrogenated phosphatidylcholine and butanediol to prepare a mixture B; adding the mixture A and the emulsifier into the mixture B to obtain a mixture; adding the component C into the mixed material, then adding the component D, and mixing. The essence can relieve dry and tight skin and relieve skin injury irritation due to the addition of anoectochilus formosanus extract and fibronectin.
Description
Technical Field
The invention belongs to the field of skin care products, and particularly relates to a soothing and repairing essence and a preparation method thereof.
Background
Skin is the interface between the body and the external environment and is also the primary physical barrier to moisture loss. When the water content is less than 10%, the skin horny layer is too dry, and skin problems such as dermatitis and itching may be induced, so that the barrier function of the skin is impaired. In addition, active oxygen in the air component and part of the additives in the cosmetic may cause damage to keratinocytes, change the structure and function of the skin, and even convert to inflammation. Therefore, the addition of moisturizing and soothing active ingredients to cosmetics helps to maintain the structural and functional integrity of the skin barrier system, which plays a decisive role in maintaining skin elasticity and maintaining skin viability.
In summary, it is necessary to provide an essence with soothing and repairing effects.
Disclosure of Invention
The present invention aims to solve at least one of the technical problems in the prior art described above. Therefore, the invention provides a relief repair essence which comprises anoectochilus roxburghii extract and fibronectin, wherein the anoectochilus roxburghii extract is used as a relief repair efficacy component and is compounded with other components to form the essence, and the relief repair essence has the effects of relieving redness and itching, reducing water loss, moisturizing, repairing skin barriers and the like; fibronectin has effects of relieving, removing wrinkles, removing speckle, and whitening skin. The essence prepared by the combination of the extract and the extract can relieve dry and tight skin, relieve skin injury stimulation, and realize high-value application of the anoectochilus roxburghii extract and fibronectin in the field of cosmetics.
The invention also provides a preparation method of the relieving and repairing essence.
According to one aspect of the invention, a soothing and repairing essence is provided, which comprises the following components in percentage by weight of the total weight of the soothing and repairing essence:
a component: 1.00 to 2.00 percent of polyalcohol, 0.01 to 0.04 percent of EDTA-2Na, 0.30 to 0.50 percent of thickener and 70.00 to 83.5 percent of water;
and the component B comprises the following components: 0.10 to 0.30 percent of emulsifying agent, 0.05 to 0.50 percent of phytosterol, 0.30 to 0.90 percent of squalane, 0.05 to 0.16 percent of hydrogenated phosphatidylcholine and 1.00 to 4.00 percent of butanediol;
and C, component: 0.30 to 0.70 percent of antioxidant, 1.00 to 3.00 percent of butanediol, 0.34 to 0.82 percent of humectant and 10.00 to 13.00 percent of water;
and D, component: 0.30 to 0.60 percent of 1, 2-hexanediol, 0.30 to 0.70 percent of glyceroglycosides, 0.10 to 0.60 percent of fibronectin, 1.00 to 3.00 percent of anoectochilus roxburghii extract and 0.01 to 0.08 percent of citric acid.
According to a preferred embodiment of the invention, there is at least the following advantageous effect:
anoectochilus roxburghii (Anoectochilus roxburghii (wall.) Lindl.) is fresh or dried whole plant of Orchidaceae plant, and can be used for treating diseases such as hepatitis. The anoectochilus formosanus is a special traditional Chinese medicine in Fujian province, has the effects of cooling and detoxifying, nourishing yin and reducing pathogenic fire, diminishing inflammation and relieving pain, has obvious curative effects on innominate swelling and pain, fever and diarrhea, and has a great number of pharmacological effects: protecting liver, reducing blood lipid, promoting urination, tranquilizing, relieving pain, and diminishing inflammation, wherein the effects of diminishing inflammation and relieving pain can be applied to soothing cosmetics.
Fibronectin is a ubiquitous important component of the extracellular matrix, which is both a regulator of cellular activity and an important scaffold protein that maintains and directs tissue structure and extracellular matrix composition. In skin wound repair and healing, fibronectin can shorten the wound healing time and reduce wound scars, is widely used in regenerative medicine, and has effects of relieving, removing wrinkles, lightening spots and whitening in the aspect of skin care.
The essence prepared by compounding the anoectochilus roxburghii extract, fibronectin and other components has penetrability to skin, is mild and non-irritating, has the functions of relieving, calming, moisturizing, nourishing and protecting, and can reduce the irritation of external ultraviolet rays or pollution factors to sensitive skin.
In some embodiments of the invention, the polyol is methyl propylene glycol.
In some embodiments of the present invention, the thickener comprises, in percent of each component based on the total weight of the conditioning concentrate: 0.20 to 0.30 percent of polyacrylate crosslinked polymer-6,0.10 to 0.20 percent of ammonium acryloyldimethyl taurate/behenpolyether-25 methacrylate crosslinked polymer.
In some embodiments of the invention, the emulsifier is a C14-22 alcohol/C12-20 alkyl glucoside.
In some embodiments of the invention, the squalane is selected from the group consisting of squalane.
In some embodiments of the invention, the antioxidant is p-hydroxyacetophenone.
In some embodiments of the present invention, the moisturizing agent comprises, in percent of each component based on the total weight of the conditioning essence: 0.01 to 0.04 percent of sodium hyaluronate, 0.03 to 0.08 percent of beta-glucan and 0.30 to 0.70 percent of panthenol.
In some embodiments of the present invention, deionized water is selected for the water in the conditioning and conditioning essence.
According to still another aspect of the present invention, there is provided a method for preparing the soothing and repairing essence, comprising the steps of:
s1: adding polyalcohol, EDTA-2Na and a thickening agent into water, and heating and dissolving to prepare a mixture A;
s2: mixing phytosterol, squalane, hydrogenated phosphatidylcholine and butanediol to prepare a mixture B; adding the mixture A into the mixture B, adding an emulsifying agent, and mixing to obtain a mixture;
s3: and (2) adding all materials in the component C into the mixed materials in the step (S2), mixing, and then adding all materials in the component D, and mixing to obtain the relief and repair essence.
In some embodiments of the present invention, before step S1, further comprising the step of preparing an anoectochilus roxburghii extract: drying and crushing anoectochilus formosanus to obtain anoectochilus formosanus powder; and then mixing the anoectochilus roxburghii powder with water, centrifuging, and collecting supernatant to obtain the anoectochilus roxburghii extract.
Specifically, the anoectochilus formosanus is subjected to vacuum drying treatment at 45-55 ℃.
Specifically, the solid-to-liquid ratio of the anoectochilus roxburghii powder to water is 1: 100-4: 100.
specifically, after mixing the anoectochilus roxburghii powder and water, treating the mixture in a water bath at 75-90 ℃ for 3-3.5 h, centrifuging the mixture for 5-6 min at 6800-7200 r/min, and collecting supernatant to obtain the anoectochilus roxburghii extract.
More specifically, after the anoectochilus roxburghii powder and water are mixed, the anoectochilus roxburghii powder and water are treated in a water bath at 75-90 ℃ for 3 hours, and centrifugation is carried out for 5 minutes at 7000r/min, and supernatant fluid is collected to obtain the anoectochilus roxburghii extract.
In some embodiments of the invention, the temperature of the heating in step S1 is 80 to 90 ℃.
In some embodiments of the present invention, step S2 is to heat the plant sterol and the squalane to 85-90 ℃, stir at a slow speed until all the components are dissolved, and add the hydrogenated phosphatidylcholine which is completely dissolved in the butanediol in advance, and mix the components to prepare the mixture B.
In some embodiments of the present invention, adding each of the materials in the component C in step S3 includes: and (3) after the temperature is reduced to 55-65 ℃, adding a humectant which is dissolved in water in advance into the mixed material in the step (S2), and then adding an antioxidant which is dissolved in butanediol in advance.
In some preferred embodiments of the present invention, each of the materials added to the component C in step S3 comprises: and (3) after the temperature is reduced to 55-65 ℃, adding sodium hyaluronate and beta-glucan which are dissolved in water in advance into the mixed material in the step (S2), adding p-hydroxyacetophenone which is dissolved in butanediol in advance, and finally adding panthenol.
In some embodiments of the present invention, step S3 is performed after the temperature is reduced to below 45 ℃, and each material in the component D is added and mixed to obtain the soothing and repairing essence.
Drawings
The invention is further described with reference to the accompanying drawings and examples, in which:
FIG. 1 is a graph showing the evaluation result of skin feel of the soothing and repairing essence 2 in the test example of the present invention;
FIG. 2 is a graph showing the results of the test of the amount of percutaneous moisture loss before and after the subject uses the soothing and repairing essence 2 in the test example of the present invention;
FIG. 3 is a graph showing the results of the test of the skin itching degree of the subject after the skin of the subject is stimulated with capsaicin in the test example of the present invention, before and after the use of the soothing and repairing essence 1.
Detailed Description
The following detailed description of embodiments of the invention, examples of which are illustrated in the accompanying drawings, and the embodiments described by reference to the drawings are illustrative only and are not to be construed as limiting the invention.
In the description of the present invention, unless otherwise specifically defined, terms such as stirring, centrifugation, etc. should be construed broadly, and those skilled in the art can reasonably determine the specific meaning of the terms in the present invention in combination with the specific contents of the technical scheme.
In the description of the present invention, reference to the term "one embodiment," "some embodiments," etc., means that a particular feature, material, or characteristic described in connection with the embodiment is included in at least one embodiment of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment. Furthermore, the particular features, materials, or characteristics may be combined in any suitable manner in any one or more embodiments.
The test methods used in the examples are conventional methods unless otherwise specified; the materials, reagents and the like used, unless otherwise specified, are those commercially available.
Example 1
The embodiment prepares the soothing and repairing essence 1, and the essence comprises the following components in percentage by weight:
a component: 1.60% of methyl propylene glycol, 0.02% of EDTA-2Na, 60.22% of polyacrylate crosslinked polymer, 0.12% of ammonium acryloyldimethyl taurate/behenate polyether-25 methacrylate crosslinked polymer and 78.12% of deionized water;
and the component B comprises the following components: 0.20% of C14-22 alcohol/C12-20 alkyl glucoside, 0.50% of phytosterol, 0.50% of elemene, 0.10% of hydrogenated phosphatidylcholine and 2.00% of butanediol;
and C, component: 0.50% of p-hydroxyacetophenone, 2.00% of butanediol, 0.03% of sodium hyaluronate, 0.05% of beta-glucan, 0.50% of panthenol and 10.50% of deionized water;
and D, component: 0.50% of 1, 2-hexanediol, 0.50% of glyceroglycosides, 0.50% of fibronectin, 1.50% of anoectochilus roxburghii extract and 0.04% of citric acid.
The preparation method comprises the following specific steps:
(1) Vacuum drying herba Anoectochili Roxburghii at 50deg.C, pulverizing in Chinese medicinal material pulverizer, and sieving with 60 mesh sieve to obtain herba Anoectochili Roxburghii powder; the anoectochilus roxburghii powder and deionized water are mixed according to a solid-to-liquid ratio of 1:100, processing in water bath at 80deg.C for 3h, centrifuging at 7000r/min for 5min, and collecting supernatant to obtain herba Anoectochili Roxburghii extract.
(2) Adding methyl propylene glycol, EDTA-2Na, polyacrylate crosslinked polymer-6 and acrylamide dimethyl taurate/behenpolyether-25 methacrylate crosslinked polymer in the component A into deionized water, heating to 85 ℃ for dispersion and dissolution, homogenizing for 3min at a high speed, stirring and dispersing uniformly, vacuumizing and preserving heat for 20min for defoaming, and thus obtaining the mixture A.
(3) Heating plant sterol and elemene in the component B to 90 ℃, stirring slowly until all the plant sterol and the elemene are dissolved, adding hydrogenated phosphatidylcholine which is completely dissolved in butanediol in advance, and stirring uniformly to obtain a mixture B. And adding the mixture A into the mixture B, simultaneously adding the C14-22 alcohol/C12-20 alkyl glucoside, homogenizing at a high speed for 3min, stirring and dispersing uniformly, vacuumizing and preserving heat for 20min to remove foam, and thus obtaining the mixture.
(4) And (3) after the temperature is reduced to 55-65 ℃, adding sodium hyaluronate and beta-glucan which are dispersed and dissolved in deionized water in advance, adding p-hydroxyacetophenone which is heated and dissolved in advance completely in butanediol, finally adding panthenol, and stirring uniformly.
(5) And (3) after the temperature is reduced to below 45 ℃, adding 1, 2-hexanediol, glyceroglycosides, fibronectin, anoectochilus roxburghii extract and citric acid into the component D, stirring uniformly, and discharging to obtain the relief repair essence 1.
Example 2
The embodiment prepares the soothing and repairing essence 2, and the essence comprises the following components in percentage by weight:
a component: 1.60% of methyl propylene glycol, 0.02% of EDTA-2Na, 60.22% of polyacrylate crosslinked polymer, 0.12% of ammonium acryloyldimethyl taurate/behenate polyether-25 methacrylate crosslinked polymer and 77.60% of deionized water;
and the component B comprises the following components: 0.20% of C14-22 alcohol/C12-20 alkyl glucoside, 0.50% of phytosterol, 0.50% of elemene, 0.10% of hydrogenated phosphatidylcholine and 2.00% of butanediol;
and C, component: 0.50% of p-hydroxyacetophenone, 2.00% of butanediol, 0.03% of sodium hyaluronate, 0.05% of beta-glucan, 0.50% of panthenol and 10.50% of deionized water;
and D, component: 0.50% of 1, 2-hexanediol, 0.50% of glyceroglycosides, 0.50% of fibronectin, 2.00% of anoectochilus roxburghii extract and 0.06% of citric acid.
The preparation method is the same as in example 1.
Example 3
The embodiment prepares the soothing and repairing essence 3, and the essence comprises the following components in percentage by weight:
a component: 1.60% of methyl propylene glycol, 0.02% of EDTA-2Na, 60.22% of polyacrylate crosslinked polymer, 0.12% of ammonium acryloyldimethyl taurate/behenate polyether-25 methacrylate crosslinked polymer and 77.08% of deionized water;
and the component B comprises the following components: 0.20% of C14-22 alcohol/C12-20 alkyl glucoside, 0.50% of phytosterol, 0.50% of elemene, 0.10% of hydrogenated phosphatidylcholine and 2.00% of butanediol;
and C, component: 0.50% of p-hydroxyacetophenone, 2.00% of butanediol, 0.03% of sodium hyaluronate, 0.05% of beta-glucan, 0.50% of panthenol and 10.50% of deionized water;
and D, component: 0.50% of 1, 2-hexanediol, 0.50% of glyceroglycosin, 0.50% of fibronectin, 2.50% of anoectochilus roxburghii extract and 0.08% of citric acid.
The preparation method is the same as in example 1.
Example 4
The embodiment prepares the soothing and repairing essence 4, and the essence comprises the following components in percentage by weight:
a component: 1.60% of methyl propylene glycol, 0.02% of EDTA-2Na, 60.22% of polyacrylate crosslinked polymer, 0.12% of ammonium acryloyldimethyl taurate/behenate polyether-25 methacrylate crosslinked polymer and 78.74% of deionized water;
and the component B comprises the following components: 0.20% of C14-22 alcohol/C12-20 alkyl glucoside, 0.50% of phytosterol, 0.50% of elemene, 0.10% of hydrogenated phosphatidylcholine and 2.00% of butanediol;
and C, component: 0.40% of p-hydroxyacetophenone, 2.00% of butanediol, 0.03% of sodium hyaluronate, 0.05% of beta-glucan, 0.50% of panthenol and 10.50% of deionized water;
and D, component: 0.50% of 1, 2-hexanediol, 0.50% of glyceroglycosides, 0.50% of fibronectin, 1.00% of anoectochilus roxburghii extract and 0.02% of citric acid.
The preparation method is the same as in example 1.
Test examples
The efficacy of the soothing and repairing essence prepared in the examples was tested in this test example. Wherein:
1. skin feel evaluation: the skin feel of the product was evaluated on the soothing and repairing essence 2 prepared in example 2.
Subjects 35 persons with healthy skin, no history of skin disease and allergy were randomly selected, and the average age was 35 years. In the sensory evaluation, a scoring test method is adopted for sensory evaluation, 6 sensory indexes of glossiness, spreadability, absorbability, sticky feel, refreshing feel and moist feel of the skin are established, and each sensory index is subjected to 10-degree scoring evaluation. After the subject uses the soothing and repairing essence 2, the sensory indexes are respectively scored and evaluated, and the average result is shown in fig. 1. Fig. 1 shows that the average scores of the glossiness, spreadability, absorbability, viscosity, refreshing feel, and moisturizing feel of the soothing and repairing essence 2 are 8.5, 9.1, 8.6, 8.8, 9.3, and 9.6, respectively, all of which are 8.5 or more. The soothing and repairing essence 2 containing anoectochilus roxburghii extract and fibronectin is good in skin feel by integrating various skin feel evaluation indexes.
2. Moisture percutaneous loss (TEWL) measurement: the moisturizing efficacy of the soothing and repairing essence 2 prepared in example 2 was evaluated.
Referring to industry standard QB/T4256-2011, the skin dryness and the loss of skin surface moisture before and after using the soothing essence 2 for a rough female aged 18-55 years were measured by using a Tewameter TM300 (skin moisture loss TEWL tester), and the results are shown in FIG. 2. Fig. 2 shows that the amount of percutaneous moisture loss was significantly reduced (p < 0.05) after 14 and 28 days of continuous use of the soothing and repairing essence 2, compared to before the use of the soothing and repairing essence 2 (i.e., D0), indicating that the soothing and repairing essence 2 comprising anoectochilus roxburghii extract and fibronectin has a good effect of repairing skin barrier.
3. Evaluation of itching relieving degree: the antipruritic effect of the soothing and repairing essence 1 prepared in example 1 was evaluated.
Subjects 35 persons with healthy skin, no history of skin disease and allergy were randomly selected, with an average age of 35 years. The skin of the subject is stimulated with 5.0% capsaicin to cause skin allergy, then the skin allergy is coated with the soothing and repairing essence 1, and the related states of the skin in different periods are judged by the subject complaining of the itching degree, and the result is shown in figure 3. Fig. 3 shows that after capsaicin stimulation, the itching degree is reduced to 67.43% when the soothing and repairing essence 1 is smeared for 10min, and the anti-inflammatory effect is good; after 30min and 60min of application, the itching degree was reduced to 58.26% and 48.21%, respectively. It is shown that the soothing and repairing essence 1 containing the anoectochilus roxburghii extract and fibronectin can well inhibit skin itch.
4. And (3) evaluating the relieving effect: the soothing effect evaluation was performed on the soothing and repairing essence 1 prepared in example 1.
50 subjects were screened and a questionnaire was filled out with reference to the standard of table 1 after 1,4 weeks (28 days) of administration of the relief repair essence to 50 subjects.
Table 1 self-scoring criteria (7-level scoring)
The four points of "relieving skin burning sensation", "improving skin redness", "relieving stinging and itching" and "improving skin tolerance" were evaluated, and the results are shown in table 2.
Table 2 evaluation results of the essence for relaxation (n=50)
Table 2 shows that from a soothing aspect, four index scores averaged over 5.42 after 28 days of use, statistically more than 50% of subjects gave positive assessment of the product moisturizing effect score. Wherein 80% of subjects who "relaxed skin burning sensation" are identified on day 28; "improve skin redness" has 84% of subjects identified at day 28; "relieve stinging and itching" 86% of subjects received at day 28; "promote skin tolerance" has 78% acceptance by the subjects on day 28. The soothing and repairing essence 1 containing the anoectochilus roxburghii extract and fibronectin can effectively relieve skin and has good moisturizing effect.
While the embodiments of the present invention have been described in detail, the present invention is not limited to the above embodiments, and various changes can be made without departing from the spirit of the present invention within the knowledge of those skilled in the art. Furthermore, embodiments of the invention and features of the embodiments may be combined with each other without conflict.
Claims (10)
1. The soothing and repairing essence is characterized by comprising the following components in percentage by weight of the total weight of the soothing and repairing essence:
a component: 1.00 to 2.00 percent of polyalcohol, 0.01 to 0.04 percent of EDTA-2Na, 0.30 to 0.50 percent of thickener and 70.00 to 83.5 percent of water;
and the component B comprises the following components: 0.10 to 0.30 percent of emulsifying agent, 0.05 to 0.50 percent of phytosterol, 0.30 to 0.90 percent of squalane, 0.05 to 0.16 percent of hydrogenated phosphatidylcholine and 1.00 to 4.00 percent of butanediol;
and C, component: 0.30 to 0.70 percent of antioxidant, 1.00 to 3.00 percent of butanediol, 0.34 to 0.82 percent of humectant and 10.00 to 13.00 percent of water;
and D, component: 0.30 to 0.60 percent of 1, 2-hexanediol, 0.30 to 0.70 percent of glyceroglycosides, 0.10 to 0.60 percent of fibronectin, 1.00 to 3.00 percent of anoectochilus roxburghii extract and 0.01 to 0.08 percent of citric acid.
2. The soothing and repairing concentrate of claim 1 wherein the polyol is methyl propylene glycol.
3. The conditioning essence of claim 1, wherein the thickener comprises, in percent of each component based on the total weight of the conditioning essence: 0.20 to 0.30 percent of polyacrylate crosslinked polymer-6,0.10 to 0.20 percent of ammonium acryloyldimethyl taurate/behenpolyether-25 methacrylate crosslinked polymer.
4. The soothing and conditioning essence according to claim 1, characterized in that the emulsifier is a C14-22 alcohol/C12-20 alkyl glucoside.
5. The soothing and repairing essence according to claim 1, wherein the antioxidant is p-hydroxyacetophenone.
6. The conditioning essence of claim 1, wherein the humectant comprises, in percent of each component based on the total weight of the conditioning essence: 0.01 to 0.04 percent of sodium hyaluronate, 0.03 to 0.08 percent of beta-glucan and 0.30 to 0.70 percent of panthenol.
7. The method for preparing the soothing and repairing essence according to any one of claims 1 to 6, characterized by comprising the following steps:
s1: adding polyalcohol, EDTA-2Na and a thickening agent into water, and heating and dissolving to prepare a mixture A;
s2: mixing phytosterol, squalane, hydrogenated phosphatidylcholine and butanediol to prepare a mixture B; adding the mixture A into the mixture B, adding an emulsifying agent, and mixing to obtain a mixture;
s3: and (2) adding all materials in the component C into the mixed materials in the step (S2), mixing, and then adding all materials in the component D, and mixing to obtain the relief and repair essence.
8. The method according to claim 7, further comprising the step of preparing an extract of anoectochilus roxburghii, before step S1: drying and crushing anoectochilus formosanus to obtain anoectochilus formosanus powder; and then mixing the anoectochilus roxburghii powder with water, centrifuging, and collecting supernatant to obtain the anoectochilus roxburghii extract.
9. The process according to claim 7, wherein step S2 is carried out by heating the plant sterol and squalane to 85-90 ℃, stirring until the plant sterol and squalane are completely dissolved, adding the hydrogenated phosphatidylcholine completely dissolved in advance with the butanediol, and mixing to obtain the mixture B.
10. The method according to claim 7, wherein the adding of each material in the component C in step S3 comprises: when the temperature is reduced to 55-65 ℃, adding humectant dissolved in water in advance into the mixed material in the step S2, and then adding antioxidant dissolved in butanediol in advance;
preferably, in the step S3, after the temperature is reduced to below 45 ℃, adding all materials in the component D, and mixing to obtain the soothing and repairing essence.
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