CN117442683A - A Chinese medicinal composition for treating burn and scald, and its ointment - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating burns and scalds, which consists of lithospermum, angelica, rheum officinale, asarum, angelica dahurica, red paeony root, gardenia, bletilla striata, dried alum and borneol.

Description

A Chinese medicinal composition for treating burn and scald, and its ointment

Technical Field

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating burns and scalds and ointment thereof.

Background

Radix Arnebiae can be used as medicine, and has effects of relieving pain, removing toxic substances, promoting blood circulation, relieving inflammation, inhibiting bacteria, preventing wound infection, and promoting wound healing. Can be used for treating skin rash, measles, macula, constipation, ulcer, parotitis, burn, and scald. The "skin-moistening cream" described in Ming dynasty Chen Shigong, "surgical Authenticity" (volume IV) comprises the following components: "four two of sesame oil, five Chinese angelica, one lithospermum, five yellow wax, the efficacy is: the sesame oil is used in the skin-moistening ointment, the lithospermum and the angelica sinensis are added at one place, the skin-moistening ointment can be applied with the skin-sore and the yellow wax effect is collected, and then the lard is added on the basis, so that the purple cloud ointment is developed, and the formula of the purple cloud ointment collected in Chinese pharmacopoeia is as follows: the efficacy of the sesame oil, the lithospermum, the angelica, the radix saposhnikoviae, the rehmannia root, the angelica dahurica, the frankincense and the myrrh is as follows: the traditional Ziyun ointment is still poor in treatment effect for burn and scald due to the fact that the wound is difficult to heal, poor in sterilization and anti-inflammation effects and common in the wound surface of burn and scald due to the effects of promoting blood circulation to remove blood stasis, detoxifying and relieving pain, dehumidifying and relieving itching and the like, and the traditional Ziyun ointment is still poor in treatment effect for burn and scald. Therefore, the traditional Ziyun ointment needs to be improved, and the ointment for treating burns and scalds with better treatment effect is developed.

Disclosure of Invention

Therefore, the traditional Chinese medicine composition for treating burns and scalds and the ointment thereof are developed finally through continuous improvement and perfection on the basis of the traditional Ziyun ointment, and the traditional Chinese medicine composition for treating burns and scalds has the effects of diminishing inflammation, promoting granulation, drawing out toxin, removing putrefaction, quickly relieving pain, promoting pus discharge, stimulating the growth of epidermis and dermis tissues and no scar formation after healing.

The technical scheme of the invention is as follows:

a traditional Chinese medicine composition for treating burns and scalds consists of the following raw materials in parts by weight:

80-120 parts of lithospermum, 80-120 parts of angelica, 40-60 parts of rheum officinale, 14-35 parts of asarum, 15-25 parts of radix angelicae, 15-25 parts of radix paeoniae rubra, 15-25 parts of fructus gardeniae, 20-40 parts of bletilla striata, 20-40 parts of dried alum and 5-15 parts of borneol.

Further, it is composed of the following raw materials:

100 parts of lithospermum, 100 parts of angelica, 50 parts of rheum officinale, 20 parts of asarum, 20 parts of radix angelicae, 20 parts of radix paeoniae rubra, 20 parts of gardenia, 30 parts of bletilla striata, 30 parts of dried alum and 10 parts of borneol.

Based on the same inventive concept, the invention also provides an ointment for treating burns and scalds, which is prepared from the traditional Chinese medicine composition.

Further, the raw materials for preparing the traditional Chinese medicine composition comprise sesame oil, beeswax, refined lard and fat-soluble laurocapram.

Further, 1000-2000ml of linseed oil, 80-100g of beewax and 20-45g of refined lard are added into 100g of lithospermum.

Further, 2ml of fat-soluble laurocapram was added to each 100ml of the ointment.

Further, the preparation method comprises the following steps:

1) Frying the sesame oil until the sesame oil is cooked, and adding refined lard to melt;

2) Sequentially frying radix Arnebiae, radix Angelicae sinensis, herba asari, radix et rhizoma Rhei, radix Angelicae Dahuricae, radix Paeoniae Rubra, and fructus Gardeniae in the oil of step 1);

when the lithospermum is fried, the oil in the pot is changed into bright red, then the residues are filtered, and then other medicines are sequentially added, the color of the medicines is fried until the color is changed into dark brown, and the residues are filtered.

3) Separating from fire, filtering, adding Cera flava into the medicinal liquid, slowly stirring to melt, and observing hardness during the process to obtain medicinal oil coagulation;

4) When the temperature of the medicinal oil is reduced to 50 ℃, adding the bletilla striata powder and the dried alum powder which are sieved by a 80-mesh sieve, stirring uniformly, then adding the borneol powder, and finally adding the fat-soluble laurocapram according to a proportion, stirring uniformly;

5) Cooling the ointment with cold water for 48 hr to remove toxic fire, and bottling.

Based on the same inventive concept, the invention also provides a spray for treating burns and scalds, which is prepared from the traditional Chinese medicine composition.

The pharmacology of the raw materials used in the invention is as follows:

radix Arnebiae: sweet and cold, enter heart and liver meridians, cool blood, activate blood, clear heat and detoxify. The radix Arnebiae extract has inhibiting effect on Staphylococcus aureus, ganoderma, suppurative bacteria, and Escherichia coli, and can accelerate growth of epithelial tissue, so that it can be used for treating burn and scald.

Chinese angelica root: pungent, bitter and warm in property, enter heart, liver and spleen meridians. Hemostasis, blood circulation promoting, pain relieving, and intestine moistening. Radix Angelicae sinensis has antibacterial effect on in vitro dysentery, typhoid, paratyphoid, escherichia coli, diphtheria bacillus, vibrio cholerae, A, B hemolytic streptococcus, etc. It has effects in promoting wound healing, promoting topical congestion, and infiltration of leukocyte and fiber, and promoting regeneration of new epithelium, and has effects in caring skin and promoting granulation.

Rhubarb: bitter and cold. Purgation and accumulation, clearing heat and purging fire, detoxicating, promoting blood circulation and removing blood stasis. The large Song Guoyi has never been said: the heat-syndrome is prevailing, bitter in flavor and diarrhea, bitter in rhubarb, and stasis-heat is removed. "

Asarum herb: pungent and warm. The product has strong fragrance, good channeling property, and good effects of dispelling wind, dispelling cold and relieving pain. The invention is added into the medicine composition, firstly takes the property of channeling and relieving pain, and secondly, the property of bitter and cold of other medicines is reversed, so that the medicine composition is cold-proof, and can force heat in the interior, and the skin is seriously injured.

Radix angelicae: pungent and warm. Swelling and pus expelling, pain relieving and granulation promoting, and asarum together with the Chinese medicinal herbs can enhance the effect of pain relieving, and prevent bitter and cold of the Chinese medicinal herbs and force heat to the interior.

Radix paeoniae rubra: bitter and slightly cold. It can dispel stasis, remove stagnation, dispel swelling, remove abscess, and alleviate pain.

Fructus Gardeniae: bitter and cold. Purging pathogenic fire, relieving restlessness, clearing heat, promoting diuresis, cooling blood and removing toxic substances. All sores and ulcers belong to heart, and are good at clearing heat from heart, lung and stomach meridians to remove heat and toxic materials. The 'materia medica outline' cloud: for hematemesis, epistaxis, bloody dysentery, bloody bleeding, stranguria with blood, injury, blood stasis, overstrain due to typhoid fever, headache due to heat syncope, hernia and fire injury. The external application of the product has the effect of detumescence and pain relief on traumatic swelling and pain.

Bletilla striata: bitter, sweet, astringent and slightly cold. Astringing to stop bleeding, detumescence and promoting granulation. The 'materia medica outline' cloud: can enter lung to stop bleeding, promote tissue regeneration and treat sore.

Drying alum: sour, astringent and cold. Astringing wet sore, stopping bleeding and eliminating slough.

Sesame oil: sweet in flavor, slightly cold in nature, moistens dryness, detoxifies, and generates alopecia, and can moisten skin and supplement the function of lard for external use.

Beeswax: has effects of astringing, healing sore, promoting granulation, relieving pain, and moistening skin, and can keep granulation growth parallel to skin surface. It is used for treating ulcer, ecthyma, erosion, wound, burn, and scald.

Borneol: pungent, bitter and slightly cold. It is very suitable for treating burn and scald, with the actions of clearing heat, relieving pain, removing necrotic tissue, promoting granulation, and resolving stagnation fire.

Fat-soluble laurocapram: organic compound, molecular formula is C18H35NO, colorless, odorless and transparent viscous liquid. Is an absorption enhancer, and is one of the most effective absorbents for both lipophilic and hydrophilic substances.

The pathogenesis of burns and scalds is that heat toxin enters the skin and is invaded by the skin, the skin is made into pus, the heat toxin enters the skin and is accumulated in the scalds of the human body, so the invention aims at the pathogenesis of the burns and scalds by using medicines such as rhubarb, red paeony root, gardenia, borneol and the like which are bitter and cold, clearing away heat and toxic materials, relieving swelling and pain, taking the property of fleeing and relieving pain by asarum, and counter-assisting the property of bitter and cold of other medicines, enhancing the analgesic effect by using dahurian angelica and asarum, and preventing the bitter and cold of other medicines, expelling the heat in the skin, removing the heat toxin, especially aiming at the inflamed sore surface, can promote the liquefied discharge of necrotic skin tissues and fat tissues, and is matched with dried alum to astringe wet sores, lithospermum and angelica sinensis diminish inflammation and promote regeneration of new epithelium tissues, promote wound healing, and no scar is formed after healing. The invention is especially suitable for treating I-II degree burns and scalds, and the cure rate reaches 100% through clinical verification.

The invention can also be used for treating various skin diseases, such as alopecia areata, tinea alba, vitiligo, tinea manuum, rhagadia, ulcer, pruritus and other dry skin diseases.

Detailed Description

Reference now will be made in detail to embodiments of the invention, one or more examples of which are described below. Each example is provided by way of explanation, not limitation, of the invention. Indeed, it will be apparent to those skilled in the art that various modifications and variations can be made to the present invention without departing from the scope or spirit of the invention. For example, features illustrated or described as part of one embodiment can be used on another embodiment to yield still a further embodiment.

Accordingly, it is intended that the present invention cover such modifications and variations as fall within the scope of the appended claims and their equivalents. Other objects, features and aspects of the present invention will be disclosed in or be apparent from the following detailed description. It is to be understood by one of ordinary skill in the art that the present discussion is a description of exemplary embodiments only, and is not intended as limiting the broader aspects of the present invention. The invention is further illustrated below with reference to examples.

Example 1: a traditional Chinese medicine composition for treating burns and scalds consists of the following raw materials in parts by weight:

100g of lithospermum, 100g of angelica, 50g of rheum officinale, 20g of asarum, 20g of radix angelicae, 20g of radix paeoniae rubra, 20g of gardenia, 30g of bletilla striata, 30g of dried alum and 10g of borneol.

The embodiment is suitable for the wound surface with more liquid seepage, when in use, the raw materials are crushed and pass through a 80-mesh sieve, and then ultraviolet irradiation is carried out for one hour for sterilization, so that a proper amount of medicinal powder can be directly sprayed on the wound surface or cooled boiled water is mixed into a thin mud shape to be coated on an affected part, the liquid seepage absorption is faster, and the effect is good.

Example 2: an ointment for treating burns and scalds consists of the following raw materials in parts by weight:

100g of lithospermum, 100g of angelica, 50g of rheum officinale, 20g of asarum, 20g of radix angelicae, 20g of red paeony root, 20g of gardenia, 30g of bletilla striata, 30g of dried alum, 10g of borneol, 1500ml of linseed oil, 80-100g of beewax, 30g of refined lard and 2ml of laurocapram.

The preparation method comprises the following steps:

1) Frying the sesame oil until the sesame oil is cooked, and adding refined lard to melt;

2) Sequentially frying radix Arnebiae, radix Angelicae sinensis, herba asari, radix et rhizoma Rhei, radix Angelicae Dahuricae, radix Paeoniae Rubra, and fructus Gardeniae in the oil of step 1);

when the lithospermum is fried, the oil in the pot is changed into bright red, then the residues are filtered, and then other medicines are sequentially added, the color of the medicines is fried until the color is changed into dark brown, and the residues are filtered.

3) Separating from fire, filtering, adding Cera flava into the medicinal liquid, slowly stirring to melt, and observing hardness during the process to obtain medicinal oil coagulation;

4) When the temperature of the medicinal oil is reduced to 50 ℃, adding the bletilla striata powder and the dried alum powder which are sieved by a 80-mesh sieve, stirring uniformly, then adding the borneol powder, and finally adding the fat-soluble laurocapram according to a proportion, stirring uniformly;

5) Cooling the ointment with cold water for 48 hr to remove toxic fire, and bottling.

When the preparation is used, the wound surface can be disinfected by using an iodophor firstly to remove impurities, then the base part of the large and small blisters is pumped by using a 5ml needle tube to permeate liquid, the blisters are not cut off, the ointment is directly applied to the affected part after the iodophor is slightly dried, the wound surface is exposed, the wound surface is not required to be wrapped, the wound surface can be wrapped by using a disinfection gauze at night so as to avoid sticking clothes, the wound surface is applied twice a day for 12 hours, and the wound surface can be applied for three times a day for 6-8 hours for a serious patient.

The embodiment is applied to hundreds of burn and scald patients, wherein 67 cases are I-II degree burn and scald patients, the rest is more than III degree burn and scald patients, the upper patient can be used within 1-10 days of burn and scald, the effective rate is 100%, especially for the I-II degree burn and scald cure rate is 100%, the pain is obviously relieved in the same day of application, and the skin temperature of an affected part can be reduced; the medicine is used for 2 times, pain can be effectively controlled, and the expression of a patient is free and stable; the medicine is used for 3-5 days, pain disappears, necrotic skin tissue and fat are liquefied and discharged, epidermis and dermis tissue start to grow, and the medicine is used for about 10 days to cure the burn and scald of I degree to II degree without scars.

The treatment efficacy standard is as follows:

and (3) curing: after the burn and scald is cured, the crust falls off without scars;

the method is effective: after the treatment of burns and scalds, the pain is obvious and the wounds are converged;

invalidation: the wound did not converge and there was significant exudates.

Example 3: typical case

Liu Mou A female, 55 years old, 21 st of 2023, 8 th of Megao ren clinic emergency, she crouches on the ground from yesterday evening, and 6 years old grand child runs to knock down the thermos bottle on the dining table, most of the boiling water is poured on her right arm, and she only wears short sleeves shirts due to the heat of the day. She is hard to be washed by cold water for about 10 minutes, and has no medicine available in rural areas, and finally, the rapeseed oil for cooking is coated by a rural soil method, so that the user is painful and has no sleep after one night.

The following symptoms are shown in the following formula: the whole right arm is red, swollen and purple from the elbow joint of the wrist joint, and has more than ten small and large blisters locally, and is seen as yellowish semitransparent liquid, and the scald is diagnosed. Immediately after extensive disinfection with iodophor, the free skin tissue was cut off by surgical scissors, and then the exudate was removed from the blister base with a 5ml disposable needle tube, immediately applying the ointment of example 2 to the wound surface evenly without bandaging. After half an hour the patient had reduced pain and had a pronounced cooling sensation in the arm. The patient entered a deep sleep state as the mood gradually stabilized. The ointment of example 2 was then applied once a day and a night, without bandaging in the daytime and bandaged with gauze bandages at night to prevent the bedding from being stained. The third day of the repeated diagnosis is to peel off all necrotic skin tissues, return home after re-applying the ointment, automatically coat the ointment, and make a call for inquiring on the tenth day, so that the patient can say that the skin is slightly red and tender, and has no scars and no discomfort.

Example 2: zhang Mou, female, 54 years old, is burned by splashed oil when the potato flakes are fried, and has both neck and face, belonging to the class I DEG-II DEG punctiform burn. The face and neck were then cast with tap water immediately and then applied over a large area with the ointment of example 2 after the face was stained with water. When the medicine is applied once in the evening, the second day of the burn is disappeared, the second degree of the burn is applied in a punctiform manner, the necrotic small skin tissue is dropped off in the fifth day, and a light print is left in the seventh day, so that the medicine is stopped. No trace is left on the face.

The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.

Claims (8)

1. The traditional Chinese medicine composition for treating burns and scalds is characterized by comprising the following raw materials in parts by weight:

80-120 parts of lithospermum, 80-120 parts of angelica, 40-60 parts of rheum officinale, 14-35 parts of asarum, 15-25 parts of radix angelicae, 15-25 parts of radix paeoniae rubra, 15-25 parts of fructus gardeniae, 20-40 parts of bletilla striata, 20-40 parts of dried alum and 5-15 parts of borneol.

2. The traditional Chinese medicine composition for treating burns and scalds according to claim 1, which is characterized by comprising the following raw materials:

100 parts of lithospermum, 100 parts of angelica, 50 parts of rheum officinale, 20 parts of asarum, 20 parts of radix angelicae, 20 parts of radix paeoniae rubra, 20 parts of gardenia, 30 parts of bletilla striata, 30 parts of dried alum and 10 parts of borneol.

3. An ointment for treating burns and scalds, which is characterized in that the ointment is prepared from the traditional Chinese medicine composition as claimed in claim 1 or 2.

4. An ointment for treating burns and scalds according to claim 3, which is prepared from the traditional Chinese medicine composition according to claim 1 or 2, and further comprises sesame oil, beeswax, refined lard and fat-soluble laurocapram.

5. The ointment for treating burns and scalds according to claim 4, which is characterized in that 1000-2000ml of sesame oil, 80-100g of beeswax and 20-45g of refined lard are added into every 100g of lithospermum.

6. An ointment for treating burns and scalds according to claim 5, wherein 2ml of fat-soluble laurocapram is added to every 100ml of ointment.

7. The ointment for treating burns and scalds according to claim 6, which is prepared by the following steps:

1) Frying the sesame oil until the sesame oil is cooked, and adding refined lard to melt;

2) Sequentially frying radix Arnebiae, radix Angelicae sinensis, herba asari, radix et rhizoma Rhei, radix Angelicae Dahuricae, radix Paeoniae Rubra, and fructus Gardeniae in the oil of step 1);

when the lithospermum is fried, the oil in the pot is changed into bright red, then the residues are filtered, and then other medicines are sequentially added, the color of the medicines is fried until the color is changed into dark brown, and the residues are filtered.

3) Separating from fire, filtering, adding Cera flava into the medicinal liquid, slowly stirring to melt, and observing hardness during the process to obtain medicinal oil coagulation;

4) When the temperature of the medicinal oil is reduced to 50 ℃, adding the bletilla striata powder and the dried alum powder which are sieved by a 80-mesh sieve, stirring uniformly, then adding the borneol powder, and finally adding the fat-soluble laurocapram according to a proportion, stirring uniformly;

5) Cooling the ointment with cold water for 48 hr to remove toxic fire, and bottling.

8. A spray for treating burns and scalds, which is characterized by being prepared from the traditional Chinese medicine composition as claimed in claim 1 or 2.