CN117223883A

CN117223883A - Electronic tobacco tar and electronic cigarette

Info

Publication number: CN117223883A
Application number: CN202310635008.4A
Authority: CN
Inventors: 郑志炫
Original assignee: Changning Dekang Biotechnology Shenzhen Co ltd
Current assignee: Changning Dekang Biotechnology Shenzhen Co ltd
Priority date: 2023-01-30
Filing date: 2023-05-31
Publication date: 2023-12-15

Abstract

The application provides electronic tobacco tar and an electronic cigarette, and relates to the field of electronic tobacco tar. The raw materials of the electronic cigarette oil provided by the application comprise nicotine, arecoline hydrobromide and/or arecoline, and the dosage ratio of the nicotine to the arecoline hydrobromide and/or arecoline is (1-5): (1-3), adding hydrobromic acid arecoline and/or arecoline in the formula, and assisting nicotine or nicotine salt by the hydrobromic acid arecoline and/or arecoline, so as to achieve the effect of enhancing the release and stimulation of nicotine, wherein the hydrobromic acid arecoline and the arecoline have the effect like nicotine, the stimulation effect is not as strong as nicotine, and the auxiliary enhancement effect can be achieved under the effect of mixing and blending. The arecoline hydrobromide and/or the arecoline are added into the electronic tobacco tar, so that the consumption of nicotine can be greatly reduced, and even only half of the normal consumption of nicotine can be realized, thereby greatly reducing the toxicity of the electronic tobacco tar, reducing the harm to human bodies and being beneficial to human health.

Description

Electronic tobacco tar and electronic cigarette

Technical Field

The application relates to the field of electronic tobacco tar, in particular to electronic tobacco tar and electronic cigarettes.

Background

At present, most of electronic cigarette oil on the market is prepared by adding 99% of pure nicotine or mixed nicotine salt, and the nicotine brings strong irritation to the throat and nasal cavity of a human body and simultaneously meets the addiction of smoking people to nicotine. The nicotine content of the electronic cigarette oil sold in the market is approximately 18 mg/ml-50 mg/ml, so that most people can select a nicotine salt tobacco oil product with the nicotine content of 40 mg/ml-50 mg/ml in order to meet the stimulation caused by high-strength nicotine intake, and the high-concentration nicotine is easy to cause harm to human bodies.

Nicotine can produce serious dependence and addiction to the nervous system; also can stimulate respiratory tract mucous membrane of respiratory system, resulting in inflammatory reaction; for the cardiovascular system, the heart rate is increased, the blood pressure is increased, the vascular intima is damaged, and the risk of thrombus is increased; has effects in suppressing appetite of digestive system, and increasing risk of gastric ulcer and duodenal ulcer; the oxygen carrying capacity of human hemoglobin can be influenced, so that ischemia and hypoxia of various tissues and organs occur; nicotine also has a very severe carcinogenic effect and has a deleterious effect on systemic organs.

Disclosure of Invention

The application aims to provide electronic tobacco tar and electronic cigarette, and aims to solve the problem that the existing electronic tobacco tar uses high-concentration nicotine to meet the stimulation caused by high-strength nicotine intake, but the existing electronic tobacco tar can cause harm to human bodies.

In order to achieve the above object, the present application provides an electronic cigarette oil, which comprises the following raw materials: nicotine, arecoline hydrobromide and/or arecoline, the mass ratio of the nicotine to the arecoline hydrobromide and/or arecoline is (1-10): (1-5).

Preferably, the mass ratio of the nicotine to the arecoline hydrobromide and/or arecoline is (1-5): (1-3).

Preferably, the mass ratio of the nicotine to the arecoline hydrobromide and/or arecoline is (1-2): 1.

preferably, the electronic cigarette oil comprises the following components in percentage by mass:

0.5 to 5 percent of nicotine;

arecoline hydrobromide and/or arecoline 0.3% -3%;

55% -80% of tobacco tar carrier.

Preferably, the electronic cigarette oil further comprises the following components in percentage by mass:

edible acid 0.5-2%.

1 to 5 percent of water.

Preferably, the tobacco tar carrier comprises: glycerol and propylene glycol, wherein a tobacco tar carrier in the electronic tobacco tar comprises the following components in percentage by mass:

10% -70% of glycerol;

10 to 70 percent of propylene glycol.

5-30% of fragrance regulator.

Preferably, the nicotine comprises 99% pure nicotine and/or nicotine salts.

The application also provides an electronic cigarette comprising the electronic cigarette oil.

Compared with the prior art, the application has the beneficial effects that:

the raw materials of the electronic cigarette oil provided by the application comprise nicotine, arecoline hydrobromide and/or arecoline, and the mass ratio of the nicotine to the arecoline hydrobromide and/or arecoline is (1-10): (1-5), adding hydrobromic acid arecoline and/or arecoline in the formula, and assisting nicotine or nicotine salt by the hydrobromic acid arecoline and/or arecoline, so as to achieve the effect of enhancing the release and stimulation of nicotine, wherein the hydrobromic acid arecoline and the arecoline have the effect like nicotine, the stimulation effect is not as strong as nicotine, and the auxiliary enhancement effect can be achieved under the effect of mixing and blending. The arecoline hydrobromide and/or the arecoline are added into the electronic tobacco tar, so that the consumption of nicotine can be greatly reduced, and even only half of the normal consumption of nicotine can be realized, thereby greatly reducing the toxicity of the electronic tobacco tar, reducing the harm to human bodies and being beneficial to human health.

Detailed Description

The term as used herein:

when an equivalent, concentration, or other value or parameter is expressed as a range, preferred range, or a range bounded by a list of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when ranges of "1 to 5" are disclosed, the described ranges should be construed to include ranges of "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a numerical range is described herein, unless otherwise indicated, the range is intended to include its endpoints and all integers and fractions within the range.

In these examples, the parts and percentages are by mass unless otherwise indicated.

"parts by mass" means a basic unit of measurement showing the mass ratio of a plurality of components, and 1 part may be any unit mass, for example, 1g may be expressed, 2.689g may be expressed, and the like. If we say that the mass part of the a component is a part and the mass part of the B component is B part, the ratio a of the mass of the a component to the mass of the B component is represented as: b. alternatively, the mass of the A component is aK, and the mass of the B component is bK (K is an arbitrary number and represents a multiple factor). It is not misunderstood that the sum of the parts by mass of all the components is not limited to 100 parts, unlike the parts by mass.

"and/or" is used to indicate that one or both of the illustrated cases may occur, e.g., a and/or B include (a and B) and (a or B).

The application provides electronic cigarette oil, which comprises the following raw materials: nicotine, hydrobromic acid arecoline and/or arecoline, wherein the raw material of the electronic cigarette oil can comprise nicotine and hydrobromic acid arecoline, nicotine and arecoline, nicotine, hydrobromic acid arecoline and arecoline. The mass ratio of the nicotine to the arecoline hydrobromide and/or the arecoline is (1-10): (1-5), the amount of hydrobromic acid arecoline and/or arecoline as a whole may be the amount of hydrobromic acid arecoline used alone, or the sum of the amounts of hydrobromic acid arecoline and arecoline used together. The dosage ratio of nicotine to arecoline hydrobromide and/or arecoline can be (1-5): 1, or (1-5): 2, or (1 to 5): 3, or (1-2): 1, or (1-3): (1-2), or (5-10): 1, or (1-10): 3, more specifically, for example, may be 1:1, or 2:1, or 3:1, or 4:1, or 5:1, or 1:2, or 1:3, or 2:3, etc.

The raw materials of the electronic cigarette oil provided by the application comprise nicotine, arecoline hydrobromide and/or arecoline, and the mass ratio of the nicotine to the arecoline hydrobromide and/or arecoline is (1-10): (1-5), adding hydrobromic acid arecoline and/or arecoline in the formula, and assisting nicotine or nicotine salt by the hydrobromic acid arecoline and/or arecoline, so as to achieve the effect of enhancing the release and stimulation of nicotine, wherein the hydrobromic acid arecoline and the arecoline have the effect like nicotine, the stimulation effect is not as strong as nicotine, and the auxiliary enhancement effect can be achieved under the effect of mixing and blending.

The oral toxicity data of the nicotine rat is LD 50=50 mg/kg, the oral toxicity data of the hydrobromic acid arecoline rat is LD 50=600 mg/kg, and the oral toxicity data of the arecoline mouse is LD50:550mg/kg. The arecoline hydrobromide and/or the arecoline are added into the electronic tobacco tar, so that the consumption of nicotine can be greatly reduced, and even only half of the normal consumption of nicotine can be realized, thereby greatly reducing the toxicity of the electronic tobacco tar, reducing the harm to human bodies and being beneficial to human health.

In a preferred embodiment, the ratio of the nicotine to the arecoline hydrobromide and/or arecoline is (1-5): 1-3.

In a preferred embodiment, the ratio of the nicotine to the arecoline hydrobromide and/or arecoline is (1-2): 1. In the dosage proportion, the arecoline hydrobromide and/or the arecoline have the most obvious effect of promoting nicotine.

In a specific scheme, the electronic cigarette oil comprises the following components in percentage by mass:

0.5 to 5 percent of nicotine;

arecoline hydrobromide and/or arecoline 0.3% -3%;

55% -80% of tobacco tar carrier.

The nicotine is also called nicotine, is a substance for providing a stimulus to electronic tobacco tar, mainly plays a role of addiction and generates nerve stimulus, and can be 99% pure nicotine, nicotine salt or a mixture of 99% pure nicotine and nicotine salt. The amount of nicotine may be, for example, 1% to 4%, or 2% to 5%, or 1% to 3%, more specifically, for example, 0.5%, 1%, 1.5%, 2%, 2.5%, 3%, 3.5%, 4%, 4.5% or 5%.

Wherein, the arecoline hydrobromide and/or arecoline mainly plays a role in assisting to enhance the release degree of nicotine and enhance the irritation, and the toxic effect is not strong with nicotine. Betulin can be extracted from betel nut or synthesized, but the betel nut has low content and unstable property; the arecoline hydrobromide is prepared by extracting arecoline from Arecae semen with ethanol, chloroform, etc., and dripping hydrobromic acid to obtain arecoline hydrobromide with stable properties. The amount of arecoline hydrobromide and/or arecoline may be, for example, 0.5% to 2%, or 1% to 3%, or 1% to 2%, more specifically, for example, 0.3%, 0.5%, 1%, 1.5%, 2%, 2.5% or 3%.

The tobacco tar carrier mainly plays a role in enabling aerosol of the electronic tobacco tar after high-temperature atomization to be plump, and meanwhile has a moisturizing effect. The tobacco tar carrier may be used in an amount of, for example, 55% to 70%, or 60% to 80%, or 60% to 70%, more specifically, for example, 55%, 57%, 60%, 62%, 65%, 66%, 69%, 70%, 72%, 74%, 75%, 77%, or 80%.

In a preferred embodiment, the electronic cigarette oil further comprises the following components in percentage by mass:

edible acid 0.5-2%.

The edible acid is mainly used as nicotine concoction acid, and is mixed with nicotine to form nicotine salt, so that irritation of nicotine is softer, and the edible acid can be edible additive acid such as benzoic acid, malic acid, citric acid, L-tartaric acid, etc. The amount of the edible acid may be, for example, 0.5% to 1.5%, or 1% to 2%, or 0.8% to 1.5%, more specifically, for example, 0.5%, 0.7%, 1%, 1.2%, 1.5%, 1.6%, 1.8% or 2%. If only nicotine is used in the electronic cigarette oil, no edible acid is added, and the problem that the aroma is damaged by strong nicotine irritation can be caused.

In another preferred embodiment, the electronic cigarette oil further comprises the following components in percentage by mass:

1 to 5 percent of water.

The water mainly plays a role in adjusting the electronic cigarette oil to be more easily moistened, so that the electronic cigarette oil can be atomized and does not feel dry to the throat, and the comfortableness of the electronic cigarette oil is improved. The amount of water may be, for example, 1% to 3%, or 2% to 5%, or 2% to 4%, more specifically, for example, 1%, 2%, 3%, 4% or 5%.

10% -70% of glycerol;

10 to 70 percent of propylene glycol.

The tobacco tar carrier is composed of glycerin and propylene glycol, so that the use effect can be improved, and if one of the glycerin and the propylene glycol is added alone, the viscosity of the electronic tobacco tar can be too thin or too thick to be used in a smoking set. The glycerol may be used in an amount of, for example, 10% to 50%, or 20% to 60%, or 30% to 50%, or 40% to 70%, more specifically, for example, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65% or 70%.

5-30% of fragrance regulator.

The flavor modifier mainly plays a role in enhancing the mouthfeel and flavor of the electronic cigarette oil formula, and comprises solid and/or liquid edible essence, wherein the edible essence is selected from any one or more of fruit essence and plant extract, for example, essential oil or essence with fragrance of various main stream foods. The fragrance modulator may be used in an amount of, for example, 5% to 20%, or 10% to 25%, or 10% to 20%, or 15% to 30%, more specifically, for example, 5%, 8%, 10%, 12%, 14%, 15%, 17%, 20%, 23%, 25%, 27% or 30%.

Embodiments of the present application will be described in detail below with reference to specific examples, but it will be understood by those skilled in the art that the following examples are only for illustrating the present application and should not be construed as limiting the scope of the present application. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention.

Example 1

The electronic cigarette oil of the embodiment 1 comprises the following components in percentage by mass: 20% of fruit essence, 2% of nicotine, 1% of benzoic acid, 2% of arecoline hydrobromide, 3% of distilled water, 20% of glycerol and 52% of propylene glycol.

The preparation method of the electronic cigarette oil in the embodiment 1 comprises the following steps:

step 1: mixing 2 parts of nicotine with 1 part of benzoic acid, adding 20 parts of propylene glycol as a mixed carrier solvent, heating and stirring, stirring for 1 hour, standing for 24 hours, and fully preparing the nicotine salt by acid-base reaction.

Step 2: and (2) adding 2 parts of arecoline hydrobromide, 20 parts of glycerol and 32 parts of propylene glycol into 20 parts of fruit essence, mixing, stirring for 20 minutes, adding the nicotine salt in the step (1) to finally mix, and stirring for 20 minutes to obtain the electronic cigarette oil of the embodiment (1).

Example 2

The electronic cigarette oil of the embodiment 2 comprises the following components in percentage by mass: 15% of fruit essence, 1% of nicotine, 0.5% of benzoic acid, 3% of arecoline hydrobromide, 4% of distilled water, 30% of glycerol and 46.5% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 2 is the same as that in embodiment 1, and will not be described here again.

Example 3

The electronic cigarette oil of the embodiment 3 comprises the following components in percentage by mass: 30% of fruit essence, 5% of nicotine, 2% of benzoic acid, 1% of arecoline hydrobromide, 5% of distilled water, 34% of glycerol and 23% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 3 is the same as that in embodiment 1, and will not be described here again.

Example 4

The electronic cigarette oil of the embodiment 4 comprises the following components in percentage by mass: 10% of fruit essence, 1% of nicotine, 0.5% of benzoic acid, 0.5% of arecoline hydrobromide, 1% of distilled water, 17% of glycerol and 70% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 4 is the same as that in embodiment 1, and will not be described here again.

Example 5

The electronic cigarette oil of the embodiment 5 comprises the following components in percentage by mass: 25% of fruit essence, 3% of nicotine, 1.5% of benzoic acid, 1% of arecoline hydrobromide, 1% of distilled water, 58.5% of glycerol and 10% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 5 is the same as that in embodiment 1, and will not be described here again.

Example 6

The electronic cigarette oil of the embodiment 6 comprises the following components in percentage by mass: 20% of fruit essence, 2% of nicotine, 2% of arecoline hydrobromide, 2% of distilled water, 34% of glycerol and 40% of propylene glycol. The preparation method of the e-cigarette oil in embodiment 6 is the same as that in embodiment 1, and will not be described here again.

Example 7

The electronic cigarette oil of the embodiment 7 comprises the following components in percentage by mass: 22% of fruit essence, 2% of nicotine, 2% of arecoline hydrobromide, 1% of benzoic acid, 25% of glycerol and 48% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 7 is the same as that in embodiment 1, and will not be described here again.

The components of the e-cigarette oils of examples 1 to 7 are shown in table 1.

Table 1 components of e-cigarette oils of examples 1 to 7

Example 8

The electronic cigarette oil of the embodiment 8 comprises the following components in percentage by mass: 20% of fruit essence, 2% of nicotine, 1% of benzoic acid, 2% of arecoline, 3% of distilled water, 20% of glycerol and 52% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 9 is the same as that in embodiment 1, and will not be described here again.

Example 9

The electronic cigarette oil of the embodiment 9 comprises the following components in percentage by mass: 15% of fruit essence, 1% of nicotine, 0.5% of benzoic acid, 3% of arecoline, 4% of distilled water, 30% of glycerol and 46.5% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 9 is the same as that in embodiment 1, and will not be described here again.

Example 10

The electronic cigarette oil of the embodiment 10 comprises the following components in percentage by mass: 30% of fruit essence, 5% of nicotine, 2% of benzoic acid, 1% of arecoline, 5% of distilled water, 34% of glycerol and 23% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 10 is the same as that in embodiment 1, and will not be described here again.

Example 11

The electronic cigarette oil of the embodiment 11 comprises the following components in percentage by mass: 10% of fruit essence, 1% of nicotine, 0.5% of benzoic acid, 0.5% of arecoline, 1% of distilled water, 17% of glycerol and 70% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 11 is the same as that in embodiment 1, and will not be described here again.

Example 12

The electronic cigarette oil of the embodiment 12 comprises the following components in percentage by mass: 25% of fruit essence, 3% of nicotine, 1.5% of benzoic acid, 1% of arecoline, 1% of distilled water, 58.5% of glycerol and 10% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 12 is the same as that in embodiment 1, and will not be described here again.

Example 13

The electronic cigarette oil of the embodiment 13 comprises the following components in percentage by mass: 20% of fruit essence, 2% of nicotine, 2% of arecoline, 2% of distilled water, 34% of glycerol and 40% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 13 is the same as that in embodiment 1, and will not be described here again.

The components of the e-cigarette oils of examples 8-13 are shown in table 2.

Table 2 components of e-cigarette oils of examples 8-13

Example 14

The electronic cigarette oil of the embodiment 14 comprises the following components in percentage by mass: 20% of fruit essence, 2% of nicotine, 1% of benzoic acid, 1% of arecoline, 1% of hydrobromic acid arecoline, 3% of distilled water, 20% of glycerin and 52% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 14 is the same as that in embodiment 1, and will not be described here again.

Example 15

The electronic cigarette oil of the embodiment 15 comprises the following components in percentage by mass: 15% of fruit essence, 1% of nicotine, 0.5% of benzoic acid, 1.5% of arecoline hydrobromide, 4% of distilled water, 30% of glycerol and 46.5% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 15 is the same as that in embodiment 1, and will not be described here again.

Example 16

The electronic cigarette oil of the embodiment 16 comprises the following components in percentage by mass: 30% of fruit essence, 5% of nicotine, 2% of benzoic acid, 0.5% of arecoline, 0.5% of hydrobromic acid arecoline, 5% of distilled water, 34% of glycerol and 23% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 16 is the same as that in embodiment 1, and will not be described here again.

Example 17

The electronic cigarette oil of the embodiment 17 comprises the following components in percentage by mass: 10% of fruit essence, 1% of nicotine, 0.5% of benzoic acid, 0.25% of arecoline hydrobromide, 1% of distilled water, 17% of glycerol and 70% of propylene glycol. The preparation method of the e-cigarette oil of embodiment 17 is the same as that of embodiment 1, and will not be described here again.

Example 18

The electronic cigarette oil of the embodiment 18 comprises the following components in percentage by mass: 25% of fruit essence, 3% of nicotine, 1.5% of benzoic acid, 0.5% of arecoline hydrobromide, 1% of distilled water, 58.5% of glycerol and 10% of propylene glycol. The preparation method of the e-cigarette oil of embodiment 18 is the same as that of embodiment 1, and will not be described here again.

Example 19

The electronic cigarette oil of the embodiment 19 comprises the following components in percentage by mass: 20% of fruit essence, 2% of nicotine, 1% of arecoline hydrobromide, 2% of distilled water, 34% of glycerol and 40% of propylene glycol. The preparation method of the e-cigarette liquid in embodiment 19 is the same as that in embodiment 1, and will not be described here again.

The components of the e-cigarette oils of examples 14-19 are shown in table 3.

Table 3 components of e-cigarette oils of examples 14-19

Comparative example 1

The difference from example 1, example 8 and example 14 is that the e-cigarette oil of comparative example 1 comprises the following components in mass percent: 20% of fruit essence, 4% of nicotine, 1% of benzoic acid, 3% of distilled water, 20% of glycerol and 52% of propylene glycol.

Comparative example 2

The difference from example 2, example 9 and example 15 is that the e-cigarette oil of comparative example 2 comprises the following components in mass percent: 15% of fruit essence, 2% of nicotine, 0.5% of benzoic acid, 4% of distilled water, 30% of glycerol and 48.5% of propylene glycol.

Comparative example 3

The difference from example 3, example 10 and example 16 is that the e-cigarette oil of comparative example 3 comprises the following components in mass percent: 30% of fruit essence, 5% of nicotine, 2% of benzoic acid, 5% of distilled water, 34% of glycerol and 24% of propylene glycol.

Comparative example 4

The difference between the electronic cigarette oil of comparative example 4 and the electronic cigarette oil of example 11 and the electronic cigarette oil of example 17 is that the electronic cigarette oil of comparative example 4 comprises the following components in percentage by mass: 10% of fruit essence, 1.5% of nicotine, 0.5% of benzoic acid, 1% of distilled water, 14% of glycerol and 73% of propylene glycol.

Comparative example 5

The difference from example 5, example 12 and example 18 is that the e-tar of comparative example 5 comprises the following components in mass percent: 25% of fruit essence, 4% of nicotine, 1.5% of benzoic acid, 1% of distilled water, 58.5% of glycerol and 10% of propylene glycol.

Comparative example 6

The difference from example 6, example 13 and example 19 is that the e-cigarette oil of comparative example 6 comprises the following components in mass percent: 20% of fruit essence, 2% of nicotine, 2% of distilled water, 34% of glycerol and 42% of propylene glycol.

Comparative example 7

The difference from example 1 is that the e-cigarette oil of comparative example 7 comprises the following components in mass percent: 20% of fruit essence, 2% of arecoline hydrobromide, 3% of distilled water, 20% of glycerol and 45% of propylene glycol.

Comparative example 8

The difference with example 8 is that the e-cigarette oil of comparative example 8 comprises the following components in mass percent: 20% of fruit essence, 2% of arecoline, 3% of distilled water, 20% of glycerol and 45% of propylene glycol.

Comparative example 9

The difference from example 14 is that the e-cigarette oil of comparative example 9 comprises the following components in mass percent: 20% of fruit essence, 1% of arecoline hydrobromide, 3% of distilled water, 20% of glycerol and 45% of propylene glycol.

The nicotine content and the arecoline hydrobromide content of the e-cigarette oils of each example and each comparative example are shown in table 4.

TABLE 4 Nicotine and hydrobromic acid arecoline content of E-tobacco tar for examples and comparative examples

Test example 1 sensory evaluation

The electronic cigarette oils of each example and each comparative example are respectively added into different electronic cigarettes of the same model, sensory evaluation is carried out by the test crowd in a sucking mode, the smoking crowd is preferentially selected for testing, and the test results are shown in table 5.

Table 5 results of smoking evaluation of e-tobacco tar for each example and each comparative example

Compared with the electronic cigarette oil of the comparative example 1, the electronic cigarette oil of the example 1, the example 8 and the example 14 can obviously feel that the nicotine stimulation is enhanced, the release degree and effect of nicotine are obviously stronger than those of the comparative example 1, the electronic cigarette oil of the example 1 basically can meet the requirement of smoking people on nicotine addiction after smoking 12 mouths, the electronic cigarette oil of the example 8 basically can meet the requirement of smoking people on nicotine addiction after smoking 10 mouths, the electronic cigarette oil of the example 14 basically can meet the requirement of smoking people on nicotine addiction after smoking 10 mouths, and the electronic cigarette oil of the comparative example 1 can meet the requirement of smoking people on nicotine addiction only by smoking 20-25 mouths.

The e-cigarette oils of examples 2, 9 and 15 are perceived to have substantially the same nicotine stimulating sensation as the e-cigarette oil of comparative example 2, and the e-cigarette oils of examples 2, 9 and 15 differ from the e-cigarette oil of comparative example 2 in that the e-cigarette oils of examples 2, 9 and 15 are more rapid in release of nicotine, the e-cigarette oil of example 2 satisfies the nicotine addiction requirement between the two ports 22 and 25, the e-cigarette oil of example 9 satisfies the nicotine addiction requirement between the two ports 18 and 22, the e-cigarette oil of example 15 satisfies the nicotine addiction requirement between the two ports 20 and 23, and the e-cigarette oil of comparative example 2 satisfies about 50. And although the nicotine content of the embodiment 2, the embodiment 9 and the embodiment 15 is much lower than that of the comparative example 2, the irritation effect of the embodiment 2 and the embodiment 9 is much lower, and the arecoline hydrobromide of the embodiment 9 is much higher, the arecoline hydrobromide of the embodiment 15 and the arecoline are much higher, so that the effect of the catalyst is achieved, and the arecoline hydrobromide and the arecoline can have a certain irritation effect when the nicotine addiction requirement is driven.

The electronic cigarette oils of examples 3, 10 and 16 can obviously feel the enhancement of the nicotine stimulation compared with the electronic cigarette oil of comparative example 3, the release degree of the catalytic nicotine is strong after the arecoline hydrobromide is added in example 3, the requirement of smoking people on the nicotine addiction can be met after the arecoline is sucked in example 10, the release degree of the catalytic nicotine is strong after the arecoline is added in example 10, the requirement of smoking people on the nicotine addiction can be met after the arecoline and the arecoline hydrobromide are sucked in example 16, the release degree of the catalytic nicotine is strong after the arecoline and the arecoline hydrobromide are added in example 16, the requirement of smoking people on the nicotine addiction can be met after the arecoline is sucked in example 5, and the electronic cigarette oil of comparative example 3 can be met after the arecoline is sucked in example 15.

The e-cigarette oils of examples 4, 11 and 17 are perceived to have substantially the same nicotine stimulating sensation as the e-cigarette oil of comparative example 4, the e-cigarette oils of examples 4, 11 and 17 differ from the e-cigarette oil of comparative example 4 in that the e-cigarette oils of examples 4, 11 and 17 have slightly increased release properties of nicotine, the e-cigarette oils of examples 4 and 17 meet nicotine addiction requirements after 35 puffs, the e-cigarette oils of examples 11 meet nicotine addiction requirements after 32 puffs, the e-cigarette oils of comparative example 17 meet nicotine addiction requirements after 34 puffs, and the e-cigarette oils of comparative example 4 only meet about 50 puffs. Comparison of the e-tar of examples 4, 11, and 17 with the e-tar of examples 2, 9, and 15, respectively, demonstrates that the addition of a higher dose of arecoline hydrobromide to the e-tar of example 2 accelerates the release of nicotine, the addition of a higher dose of arecoline to the e-tar of example 9 accelerates the release of nicotine, and the addition of a higher dose of arecoline hydrobromide and arecoline to the e-tar of example 15 accelerates the release of nicotine.

The electronic cigarette oils of examples 5, 12 and 18 can obviously feel the enhanced nicotine stimulation compared with the electronic cigarette oil of comparative example 5, the release degree and effect achieved by the nicotine of the electronic cigarette oils of examples 5, 12 and 18 are obviously stronger than those of the electronic cigarette oil of comparative example 5, the electronic cigarette oil of example 5 can basically meet the requirement of smoking people on nicotine addiction after smoking 10 mouths, the electronic cigarette oil of example 12 can basically meet the requirement of smoking people on nicotine addiction after smoking 8-10 mouths, the electronic cigarette oil of example 18 can basically meet the requirement of smoking people on nicotine addiction after smoking 8-10 mouths, and the electronic cigarette oil of comparative example 5 can meet the requirement of smoking people only by smoking 20-25 mouths.

The e-cigarette oils of examples 6, 13 and 19 are significantly more sensitive to nicotine irritation than the e-cigarette oil of comparative example 6, and the original irritation of nicotine is not neutralized by the acid-base reaction, so that the irritation of nicotine to the throat and nasal cavity is stronger, the release and sensory effect of nicotine in example 6 with arecoline hydrobromide are stronger than those of comparative example 6, the requirement of smoking people on nicotine addiction is met after 8 mouths are substantially sucked, the release and sensory effect of nicotine in example 13 with arecoline are stronger than those of comparative example 6, the requirement of smoking people on nicotine addiction is met after 6 mouths are substantially sucked, the release and sensory effect of nicotine in example 19 with arecoline hydrobromide and arecoline are stronger than those of comparative sample, and the requirement of smoking people on nicotine addiction is met after 8 mouths are substantially sucked, but the requirement of 50 mouths is met in comparative example 6. In addition, in example 6 compared with example 1, example 13 compared with example 8, and example 19 compared with example 14, the use of nicotine and arecoline hydrobromide and/or arecoline alone resulted in the destruction of the e-tar aroma by the intense nicotine irritation due to the absence of added edible acid.

Example 7 has a worse taste of e-cigarette oil than example 1 because no distilled water is added, which can make the taste of the user more moist.

Example 1 compared with comparative example 7, example 8 compared with comparative example 8, example 14 compared with comparative example 9, comparative example 7 does not add nicotine and only hydrobromic arecoline, comparative example 8 does not add nicotine and only arecoline, comparative example 9 does not add nicotine and only arecoline and hydrobromic arecoline, both exert only slight irritation effect, the nicotine satisfaction of smoking lovers cannot be met in the smoking process, which means that pure hydrobromic arecoline and/or arecoline cannot completely replace nicotine, and the combined use of nicotine and hydrobromic arecoline and/or arecoline has the effect of synergistically enhancing the nicotine irritation effect.

In summary, in the electronic cigarette oil according to the present application, the ratio of the nicotine content and the arecoline hydrobromide and/or the arecoline content in the formulation is the key to influence the enhanced stimulation of the electronic cigarette oil, and the arecoline hydrobromide and/or the arecoline correspond to a stimulating catalyst, so that the stimulating effect of nicotine can be amplified, and thus the nicotine intake can be greatly reduced in the use process, for example, an electronic cigarette cartridge with a nicotine content of 40mg/ml is normally used, and in the use of the electronic cigarette oil with arecoline hydrobromide and/or arecoline added, the nicotine content can be reduced to 20mg/ml, so that the same even better effect can be achieved.

Finally, it should be noted that: the above embodiments are only for illustrating the technical solution of the present application, and not for limiting the same; although the application has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical scheme described in the foregoing embodiments can be modified or some or all of the technical features thereof can be replaced by equivalents; such modifications and substitutions do not depart from the spirit of the application.

Furthermore, those skilled in the art will appreciate that while some embodiments herein include some features but not others included in other embodiments, combinations of features of different embodiments are meant to be within the scope of the application and form different embodiments. For example, in the claims below, any of the claimed embodiments may be used in any combination. The information disclosed in this background section is only for enhancement of understanding of the general background of the application and should not be taken as an acknowledgement or any form of suggestion that this information forms the prior art already known to a person skilled in the art.

Claims

1. The electronic cigarette oil is characterized by comprising the following raw materials: nicotine, arecoline hydrobromide and/or arecoline, the mass ratio of the nicotine to the arecoline hydrobromide and/or arecoline is (1-10): (1-5).

2. The e-cigarette oil of claim 1, wherein the mass ratio of the nicotine to the hydrobromic acid arecoline and/or arecoline is (1-5): (1-3).

3. The e-cigarette oil of claim 2, wherein the mass ratio of the nicotine to the hydrobromic acid arecoline and/or arecoline is (1-2): 1.

4. the e-vaping oil of claim 1, comprising the following components in mass percent:

0.5 to 5 percent of nicotine;

arecoline hydrobromide and/or arecoline 0.3% -3%;

55% -80% of tobacco tar carrier.

5. The e-vaping oil of claim 4, further comprising the following components in mass percent:

edible acid 0.5-2%.

6. The e-vaping oil of claim 4, further comprising the following components in mass percent:

1 to 5 percent of water.

7. The e-vaping stick of claim 4, wherein the stick carrier comprises: glycerol and propylene glycol, wherein a tobacco tar carrier in the electronic tobacco tar comprises the following components in percentage by mass:

10% -70% of glycerol;

10 to 70 percent of propylene glycol.

8. The e-vaping oil of claim 4, further comprising the following components in mass percent:

5-30% of fragrance regulator.

9. The e-cigarette oil of any one of claims 1-8, wherein the nicotine comprises 99% pure nicotine and/or nicotine salts.

10. An electronic cigarette comprising an electronic cigarette oil according to any one of claims 1 to 9.