CN117180389A - Traditional Chinese medicine composition for treating bone injury - Google Patents
Traditional Chinese medicine composition for treating bone injury Download PDFInfo
- Publication number
- CN117180389A CN117180389A CN202311371921.4A CN202311371921A CN117180389A CN 117180389 A CN117180389 A CN 117180389A CN 202311371921 A CN202311371921 A CN 202311371921A CN 117180389 A CN117180389 A CN 117180389A
- Authority
- CN
- China
- Prior art keywords
- parts
- traditional chinese
- chinese medicine
- radix
- treating bone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 55
- 239000000203 mixture Substances 0.000 title claims abstract description 30
- 206010061363 Skeletal injury Diseases 0.000 title claims abstract description 21
- 235000017803 cinnamon Nutrition 0.000 claims abstract description 18
- 241000180649 Panax notoginseng Species 0.000 claims abstract description 9
- 235000003143 Panax notoginseng Nutrition 0.000 claims abstract description 9
- 241000131329 Carabidae Species 0.000 claims abstract description 7
- 239000000463 material Substances 0.000 claims description 29
- 239000002994 raw material Substances 0.000 claims description 27
- 244000223760 Cinnamomum zeylanicum Species 0.000 claims description 17
- 239000000843 powder Substances 0.000 claims description 17
- 230000001954 sterilising effect Effects 0.000 claims description 17
- 235000006533 astragalus Nutrition 0.000 claims description 14
- 241000218176 Corydalis Species 0.000 claims description 13
- 244000131316 Panax pseudoginseng Species 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 11
- 238000004659 sterilization and disinfection Methods 0.000 claims description 11
- 241000427159 Achyranthes Species 0.000 claims description 9
- 241000213006 Angelica dahurica Species 0.000 claims description 9
- 241001061264 Astragalus Species 0.000 claims description 9
- 244000005700 microbiome Species 0.000 claims description 9
- 210000004233 talus Anatomy 0.000 claims description 9
- 239000006187 pill Substances 0.000 claims description 8
- 235000003181 Panax pseudoginseng Nutrition 0.000 claims description 7
- 238000004140 cleaning Methods 0.000 claims description 7
- 238000005520 cutting process Methods 0.000 claims description 6
- 238000000227 grinding Methods 0.000 claims description 6
- 238000004806 packaging method and process Methods 0.000 claims description 6
- 241000045403 Astragalus propinquus Species 0.000 claims description 5
- 241001489978 Eupolyphaga Species 0.000 claims description 5
- 230000008014 freezing Effects 0.000 claims description 5
- 238000007710 freezing Methods 0.000 claims description 5
- 241000123589 Dipsacus Species 0.000 claims description 3
- 239000002775 capsule Substances 0.000 claims description 3
- 238000003801 milling Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 238000012216 screening Methods 0.000 claims description 3
- 238000007873 sieving Methods 0.000 claims description 3
- 238000002791 soaking Methods 0.000 claims description 3
- 239000009636 Huang Qi Substances 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 238000005406 washing Methods 0.000 claims 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract description 4
- 241000723347 Cinnamomum Species 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 43
- 210000004369 blood Anatomy 0.000 description 32
- 239000008280 blood Substances 0.000 description 32
- 208000010392 Bone Fractures Diseases 0.000 description 17
- 206010017076 Fracture Diseases 0.000 description 17
- 230000003110 anti-inflammatory effect Effects 0.000 description 16
- 208000002193 Pain Diseases 0.000 description 15
- 210000004185 liver Anatomy 0.000 description 15
- 230000036407 pain Effects 0.000 description 15
- 210000000988 bone and bone Anatomy 0.000 description 13
- 230000036541 health Effects 0.000 description 13
- 230000003078 antioxidant effect Effects 0.000 description 12
- 230000001737 promoting effect Effects 0.000 description 12
- 208000024891 symptom Diseases 0.000 description 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 10
- 239000000126 substance Substances 0.000 description 10
- 230000017531 blood circulation Effects 0.000 description 9
- 230000036996 cardiovascular health Effects 0.000 description 9
- 201000010099 disease Diseases 0.000 description 9
- 230000008961 swelling Effects 0.000 description 9
- 210000002435 tendon Anatomy 0.000 description 9
- 230000003920 cognitive function Effects 0.000 description 8
- 208000027866 inflammatory disease Diseases 0.000 description 8
- 210000003734 kidney Anatomy 0.000 description 8
- 239000003963 antioxidant agent Substances 0.000 description 7
- 230000029087 digestion Effects 0.000 description 7
- 208000015181 infectious disease Diseases 0.000 description 7
- 208000014674 injury Diseases 0.000 description 7
- 230000036542 oxidative stress Effects 0.000 description 7
- 238000002360 preparation method Methods 0.000 description 7
- 241000125175 Angelica Species 0.000 description 6
- 235000001287 Guettarda speciosa Nutrition 0.000 description 6
- 230000002929 anti-fatigue Effects 0.000 description 6
- 230000009286 beneficial effect Effects 0.000 description 6
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 6
- 230000035876 healing Effects 0.000 description 6
- 210000000987 immune system Anatomy 0.000 description 6
- 230000006386 memory function Effects 0.000 description 6
- 150000003254 radicals Chemical class 0.000 description 6
- 230000001105 regulatory effect Effects 0.000 description 6
- 230000029663 wound healing Effects 0.000 description 6
- 206010011224 Cough Diseases 0.000 description 5
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 5
- 235000003140 Panax quinquefolius Nutrition 0.000 description 5
- 230000003213 activating effect Effects 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- 230000036772 blood pressure Effects 0.000 description 5
- 230000006378 damage Effects 0.000 description 5
- 235000008434 ginseng Nutrition 0.000 description 5
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
- 206010062717 Increased upper airway secretion Diseases 0.000 description 4
- 230000003712 anti-aging effect Effects 0.000 description 4
- 230000001093 anti-cancer Effects 0.000 description 4
- 206010003246 arthritis Diseases 0.000 description 4
- 238000011109 contamination Methods 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 4
- 201000006549 dyspepsia Diseases 0.000 description 4
- 239000008103 glucose Substances 0.000 description 4
- 239000012535 impurity Substances 0.000 description 4
- 238000001727 in vivo Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000003472 neutralizing effect Effects 0.000 description 4
- 208000026435 phlegm Diseases 0.000 description 4
- 206010039073 rheumatoid arthritis Diseases 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 206010000087 Abdominal pain upper Diseases 0.000 description 3
- 208000006820 Arthralgia Diseases 0.000 description 3
- 241001116742 Drynaria Species 0.000 description 3
- 206010019233 Headaches Diseases 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 3
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 230000032683 aging Effects 0.000 description 3
- 230000000843 anti-fungal effect Effects 0.000 description 3
- 230000003064 anti-oxidating effect Effects 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 238000003745 diagnosis Methods 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
- 210000002683 foot Anatomy 0.000 description 3
- 210000000245 forearm Anatomy 0.000 description 3
- 230000002496 gastric effect Effects 0.000 description 3
- 239000008187 granular material Substances 0.000 description 3
- 231100000869 headache Toxicity 0.000 description 3
- 208000019622 heart disease Diseases 0.000 description 3
- 208000006454 hepatitis Diseases 0.000 description 3
- 231100000283 hepatitis Toxicity 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 230000002401 inhibitory effect Effects 0.000 description 3
- 208000019423 liver disease Diseases 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 230000001681 protective effect Effects 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 238000005728 strengthening Methods 0.000 description 3
- 230000008736 traumatic injury Effects 0.000 description 3
- 238000010792 warming Methods 0.000 description 3
- 230000037314 wound repair Effects 0.000 description 3
- 208000004998 Abdominal Pain Diseases 0.000 description 2
- 241000382455 Angelica sinensis Species 0.000 description 2
- 208000019901 Anxiety disease Diseases 0.000 description 2
- 208000008035 Back Pain Diseases 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 241001050741 Dipsacus asperoides Species 0.000 description 2
- 208000005171 Dysmenorrhea Diseases 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 206010020649 Hyperkeratosis Diseases 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 208000008930 Low Back Pain Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 208000000112 Myalgia Diseases 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 229930189092 Notoginsenoside Natural products 0.000 description 2
- 208000001132 Osteoporosis Diseases 0.000 description 2
- 206010041497 Spermatorrhoea Diseases 0.000 description 2
- 206010000059 abdominal discomfort Diseases 0.000 description 2
- 230000000202 analgesic effect Effects 0.000 description 2
- 230000036506 anxiety Effects 0.000 description 2
- 230000000949 anxiolytic effect Effects 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 230000036770 blood supply Effects 0.000 description 2
- 210000004204 blood vessel Anatomy 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 230000005779 cell damage Effects 0.000 description 2
- 208000037887 cell injury Diseases 0.000 description 2
- 230000004087 circulation Effects 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 230000003750 conditioning effect Effects 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 210000004351 coronary vessel Anatomy 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 230000006866 deterioration Effects 0.000 description 2
- 238000001784 detoxification Methods 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000002779 inactivation Effects 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 206010022000 influenza Diseases 0.000 description 2
- 238000001802 infusion Methods 0.000 description 2
- 230000003871 intestinal function Effects 0.000 description 2
- 210000003127 knee Anatomy 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 230000036651 mood Effects 0.000 description 2
- 210000003205 muscle Anatomy 0.000 description 2
- 208000013465 muscle pain Diseases 0.000 description 2
- 201000009240 nasopharyngitis Diseases 0.000 description 2
- 230000011164 ossification Effects 0.000 description 2
- 238000013021 overheating Methods 0.000 description 2
- 238000012858 packaging process Methods 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 230000002829 reductive effect Effects 0.000 description 2
- 230000001624 sedative effect Effects 0.000 description 2
- 206010040872 skin infection Diseases 0.000 description 2
- 230000006641 stabilisation Effects 0.000 description 2
- 238000011105 stabilization Methods 0.000 description 2
- 230000004936 stimulating effect Effects 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 238000006467 substitution reaction Methods 0.000 description 2
- 208000011580 syndromic disease Diseases 0.000 description 2
- 230000004614 tumor growth Effects 0.000 description 2
- 238000009423 ventilation Methods 0.000 description 2
- 230000037303 wrinkles Effects 0.000 description 2
- KJPRLNWUNMBNBZ-QPJJXVBHSA-N (E)-cinnamaldehyde Chemical compound O=C\C=C\C1=CC=CC=C1 KJPRLNWUNMBNBZ-QPJJXVBHSA-N 0.000 description 1
- FFRBMBIXVSCUFS-UHFFFAOYSA-N 2,4-dinitro-1-naphthol Chemical compound C1=CC=C2C(O)=C([N+]([O-])=O)C=C([N+]([O-])=O)C2=C1 FFRBMBIXVSCUFS-UHFFFAOYSA-N 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 240000000031 Achyranthes bidentata Species 0.000 description 1
- 229930024421 Adenine Natural products 0.000 description 1
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 206010002869 Anxiety symptoms Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 206010007247 Carbuncle Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010008190 Cerebrovascular accident Diseases 0.000 description 1
- 206010008479 Chest Pain Diseases 0.000 description 1
- 206010008531 Chills Diseases 0.000 description 1
- 241001148495 Cibotium barometz Species 0.000 description 1
- 241000207199 Citrus Species 0.000 description 1
- 241001391944 Commicarpus scandens Species 0.000 description 1
- 208000032170 Congenital Abnormalities Diseases 0.000 description 1
- 241000830532 Corydalis yanhusuo Species 0.000 description 1
- 241000963390 Curcuma wenyujin Species 0.000 description 1
- 235000003394 Curcuma wenyujin Nutrition 0.000 description 1
- 229920000832 Cutin Polymers 0.000 description 1
- 206010061619 Deformity Diseases 0.000 description 1
- 241000123586 Dipsacaceae Species 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 235000009414 Elaeocarpus kirtonii Nutrition 0.000 description 1
- 206010051267 Facial paresis Diseases 0.000 description 1
- 206010016952 Food poisoning Diseases 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 206010027677 Fractures and dislocations Diseases 0.000 description 1
- 206010017533 Fungal infection Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 208000018522 Gastrointestinal disease Diseases 0.000 description 1
- 206010018291 Gingival swelling Diseases 0.000 description 1
- 206010018852 Haematoma Diseases 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 206010022489 Insulin Resistance Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 206010056344 Menstrual discomfort Diseases 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 208000019695 Migraine disease Diseases 0.000 description 1
- 208000031888 Mycoses Diseases 0.000 description 1
- 241000237536 Mytilus edulis Species 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 206010048685 Oral infection Diseases 0.000 description 1
- 206010068319 Oropharyngeal pain Diseases 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- 208000005374 Poisoning Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 208000004680 Rectal Fistula Diseases 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 206010041349 Somnolence Diseases 0.000 description 1
- 206010042209 Stress Diseases 0.000 description 1
- 208000006011 Stroke Diseases 0.000 description 1
- 206010042674 Swelling Diseases 0.000 description 1
- 244000236151 Tabebuia pallida Species 0.000 description 1
- 235000013584 Tabebuia pallida Nutrition 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 206010048245 Yellow skin Diseases 0.000 description 1
- 241000234299 Zingiberaceae Species 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- -1 adenine Natural products 0.000 description 1
- 229960000643 adenine Drugs 0.000 description 1
- 238000009098 adjuvant therapy Methods 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 229930013930 alkaloid Natural products 0.000 description 1
- 206010002156 anal fistula Diseases 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000001430 anti-depressive effect Effects 0.000 description 1
- 230000000702 anti-platelet effect Effects 0.000 description 1
- 239000003146 anticoagulant agent Substances 0.000 description 1
- 239000000935 antidepressant agent Substances 0.000 description 1
- 229940005513 antidepressants Drugs 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 208000024330 bloating Diseases 0.000 description 1
- 230000023555 blood coagulation Effects 0.000 description 1
- 210000001772 blood platelet Anatomy 0.000 description 1
- 229940117916 cinnamic aldehyde Drugs 0.000 description 1
- KJPRLNWUNMBNBZ-UHFFFAOYSA-N cinnamic aldehyde Natural products O=CC=CC1=CC=CC=C1 KJPRLNWUNMBNBZ-UHFFFAOYSA-N 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 206010012601 diabetes mellitus Diseases 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 230000000916 dilatatory effect Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 230000008451 emotion Effects 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 208000010770 facial weakness Diseases 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 206010016766 flatulence Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 229910052602 gypsum Inorganic materials 0.000 description 1
- 239000010440 gypsum Substances 0.000 description 1
- 230000036074 healthy skin Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 230000001631 hypertensive effect Effects 0.000 description 1
- 230000002519 immonomodulatory effect Effects 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 206010021654 increased appetite Diseases 0.000 description 1
- 230000001965 increasing effect Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007413 intestinal health Effects 0.000 description 1
- 208000017169 kidney disease Diseases 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 210000002414 leg Anatomy 0.000 description 1
- 230000000670 limiting effect Effects 0.000 description 1
- 230000000938 luteal effect Effects 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 206010027599 migraine Diseases 0.000 description 1
- 235000020638 mussel Nutrition 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 201000008383 nephritis Diseases 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- 208000021722 neuropathic pain Diseases 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 201000003068 rheumatic fever Diseases 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 230000036559 skin health Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 210000004243 sweat Anatomy 0.000 description 1
- 230000017423 tissue regeneration Effects 0.000 description 1
- 208000004371 toothache Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 210000000623 ulna Anatomy 0.000 description 1
- 208000017013 ulna fracture Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating bone injury, which is prepared from traditional Chinese medicines such as radix notoginseng, ground beetle, rhizoma drynariae, rhizoma cibotii, cinnamon, radix angelicae pubescentis and the like by adding an oral traditional Chinese medicine into the external fixation of the traditional Chinese medicine composition for treating bone injury at present.
Description
Technical Field
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating bone injury.
Background
In recent years, the traditional Chinese medicine is combined with the oral administration traditional Chinese medicine for external fixation of fracture manipulation of ancestral in China at present, and the oral administration traditional Chinese medicine combined pill is taken at the same time of external fixation of fracture manipulation for promoting blood circulation to remove blood stasis, removing blood stasis and promoting tissue regeneration, accelerating fracture healing, shortening fracture healing period, reducing medical cost, enabling the traditional Chinese medicine bone injury to be continuously developed, accelerating the whole process of development, declaration, approval and production of new application programs of old medicine, and based on the traditional Chinese medicine composition for treating bone injury, the traditional Chinese medicine composition for treating bone injury is provided.
Disclosure of Invention
Therefore, the invention provides a traditional Chinese medicine composition for treating bone injury, which has the effects of replenishing blood, activating blood, dredging collaterals, relieving pain, breaking blood, removing blood stasis, warming and tonifying kidney yang and reuniting bones and tendons.
The invention provides a traditional Chinese medicine composition for treating bone injury, which comprises the following components: radix Notoginseng, eupolyphaga Seu Steleophaga, rhizoma Drynariae, radix Angelicae sinensis, rhizoma corydalis, radix astragali, rhizoma Cibotii, pericarpium Citri Tangerinae, radix Curcumae, radix Angelicae Dahuricae, cortex Cinnamomi, radix Dipsaci, achyranthis radix, and radix Angelicae Pubescentis.
Further, the composition comprises the following components in parts by weight: 2-10 parts of wide pseudo-ginseng, 1-6 parts of ground beetle, 2-7 parts of rhizoma drynariae, 1.5-6.5 parts of Chinese angelica, 1-9 parts of rhizoma corydalis, 5-15 parts of astragalus mongholicus, 1-7.5 parts of rhizoma cibotii, 1-5 parts of dried orange peel, 3-5 parts of radix curcumae, 1.5-5 parts of radix angelicae, 3-9 parts of cinnamon, 2.5-6 parts of radix dipsaci, 4-8 parts of achyranthis bidentatae and 1-6 parts of radix angelicae pubescentis.
Further, the composition comprises the following components in parts by weight: 5 parts of wide pseudo-ginseng, 3 parts of ground beetle, 3 parts of rhizoma drynariae, 3 parts of Chinese angelica, 3 parts of rhizoma corydalis, 10 parts of astragalus, 3 parts of rhizoma cibotii, 3 parts of dried orange peel, 3 parts of radix curcumae, 3 parts of radix angelicae, 3 parts of cinnamon, 3 parts of dipsacus root, 5 parts of achyranthes and 3 parts of radix angelicae pubescentis.
Further, the composition comprises the following components in parts by weight:
s1, cleaning traditional Chinese medicinal materials; cleaning, airing and impurity removing treatment are carried out on the raw materials; in the selected medicinal materials, the rhizoma cibotii only selects rhizome parts and the radix dipsaci only selects root parts;
s2, cutting the traditional Chinese medicinal materials into proper shapes and sizes, wherein the cutting is beneficial to improving the efficacy of the traditional Chinese medicinal materials and facilitating the processing;
s3, sterilizing: sterilizing and removing microorganisms in the raw materials; ensuring sterility of Chinese medicinal materials is important to prevent spoilage, pollution and deterioration caused by microorganism; the risk of microorganism infection in the preparation process of the subsequent preparation is reduced;
s4, airing: airing the traditional Chinese medicine raw materials; solar insolation can be used to improve the taste or effect, and the control time is controlled within 3 hours;
s5, freeze grinding: the traditional Chinese medicine raw materials are frozen and then ground, and for part of traditional Chinese medicine materials, the traditional Chinese medicine raw materials are required to be ground into powder so as to prolong the storage life, and then the traditional Chinese medicine raw materials are frozen and ground by using a freezing grinder. Freezing is helpful for maintaining stability and activity of effective components in the medicinal materials, and avoiding overheating during grinding;
s6, sieving: for the ground traditional Chinese medicine powder, a screen can be used for screening to remove coarse powder and impurities, and fine powder is reserved;
s7, packaging: proper packaging is carried out to avoid being affected with damp or polluted, and the packaging is stored in a place with good drying, shadiness and ventilation;
and S8, uniformly mixing the weighed various powders according to a formula to obtain the composition.
Further, the cleaning and soaking time in the step S1 is 12 hours.
Further, the sterilization mode in the step S3 is steam sterilization, and the mixture is kept stand for 6 to 15 minutes in a steam environment; the mild nature of steam sterilization is helpful for maintaining chemical components and drug effects of the traditional Chinese medicine raw materials; steam sterilization is less likely to cause degradation or inactivation of chemical components of the medicinal materials; also helps to reduce exogenous contamination of the raw materials during the manufacturing and packaging process, as the steam can kill microorganisms in the air and prevent contamination of the raw materials when it contacts the raw materials.
Further, the S5 freeze milling is performed for 5 minutes to 15 minutes by using a freeze mill; until the blocky medicinal materials become fine powder.
Further, the powder selected in S6 is 120 mesh.
Further, the composition is prepared into any one of a tablet, a pill and a capsule.
Compared with the prior art, the traditional Chinese medicine composition for treating bone injury takes a plurality of traditional Chinese medicines as raw materials, comprises radix pseudo-ginseng, ground beetle, rhizoma drynariae, rhizoma cibotii, cinnamon, radix angelicae pubescentis and the like, is scientifically compatible, has the effects of replenishing blood and activating blood, activating collaterals and relieving pain, breaking blood and removing stasis, warming and tonifying kidney yang and setting bone and connecting tendons, simultaneously shows remarkable curative effects of benefiting joints, promoting wound repair, has short treatment course and quick response, and accelerates fracture healing.
Detailed Description
In order that the objects and advantages of the invention will become more apparent, the invention will be further described with reference to the following examples; it should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the scope of the invention.
It should be understood by those skilled in the art that these embodiments are merely for explaining the technical principles of the present invention, and are not intended to limit the scope of the present invention.
It should be noted that, in the description of the present invention, terms such as "upper," "lower," "left," "right," "inner," "outer," and the like indicate directions or positional relationships, and are based on the directions or positional relationships shown in the description, which are merely for convenience of description, but do not indicate or imply that the apparatus or elements must have a specific orientation, be constructed and operated in a specific orientation, and thus should not be construed as limiting the invention.
Furthermore, it should be noted that, in the description of the present invention, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention can be understood by those skilled in the art according to the specific circumstances.
A traditional Chinese medicine composition for treating bone injury comprises the following raw material components:
5 parts of wide pseudo-ginseng, 3 parts of ground beetle, 3 parts of rhizoma drynariae, 3 parts of Chinese angelica, 3 parts of rhizoma corydalis, 10 parts of astragalus, 3 parts of rhizoma cibotii, 3 parts of dried orange peel, 3 parts of radix curcumae, 3 parts of radix angelicae, 3 parts of cinnamon, 3 parts of dipsacus root, 5 parts of achyranthes and 3 parts of radix angelicae pubescentis.
The effects of the raw materials in the invention are as follows:
guangxi Sing, its academic name is also called Ginseng radix, taishan mountain ginseng, etc., is an important Chinese medicinal material, and is often used in Chinese medicinal preparations and health products. It has a variety of efficacy and medicinal value, some of the major effects include:
improving cardiovascular health: radix Notoginseng is effective in reducing cholesterol level and improving cardiovascular health. It can dilate coronary artery, increase heart blood supply, and reduce heart burden.
Antioxidant effect: the radix Notoginseng is rich in antioxidant substances such as notoginsenoside, and is helpful for neutralizing free radicals in vivo, reducing oxidative stress, and maintaining cell health.
Enhancing the immune system: the radix notoginseng can stimulate the immune system, strengthen the body resistance and help to fight infection and diseases.
Anti-inflammatory action: radix Notoginseng has antiinflammatory effect, and can be used for relieving inflammatory disease symptoms.
Improving memory and cognitive function: some studies indicate that guangdong ginseng may help improve memory and cognitive function, against decline in cognitive function.
Anti-fatigue: the guangqi is considered to have the anti-fatigue effect, and is helpful for improving physical strength and energy and relieving fatigue.
Promote wound healing: the radix notoginseng can accelerate the wound healing process, and is helpful for reducing swelling and promoting wound repair.
Protecting liver: researches show that the radix notoginseng has a protective effect on the liver and can help to reduce the risks of diseases such as hepatitis and the like.
Anti-aging: due to its antioxidant properties, guangqi is considered to have a certain effect against aging, helping to maintain youth and health of the skin.
Eupolyphaga Seu Steleophaga belongs to Eupolyphaga Seu Steleophaga, and is a medicinal small animal, called Eupolyphaga Seu Steleophaga, with cold nature and slightly toxic. Has the effects of removing blood stasis, stopping bleeding, relieving swelling and pain, dredging collaterals, regulating injuries, connecting tendons and bones, and the like, and is an essential medicine for the department of hematology and traumatology. Is mainly used for treating arthritis, traumatic injuries of waist and legs, closed diameter and the like.
Rhizoma drynariae, the academic name pseudo-ginseng, also called ginseng, mountain ginseng and the like, is an important traditional Chinese medicine material and is often used in traditional Chinese medicine preparations and health care products. Rhizoma drynariae has various effects and medicinal values, and the following are some main effects and uses:
improving cardiovascular health: rhizoma Drynariae is effective in reducing cholesterol level and improving cardiovascular health. It can dilate coronary artery, increase heart blood supply, and reduce heart burden.
Antioxidant effect: rhizoma Drynariae is rich in antioxidant substances such as notoginsenoside, and is effective in neutralizing free radicals in vivo, reducing oxidative stress, and maintaining cell health.
Enhancing the immune system: rhizoma Drynariae has effects in stimulating immune system, enhancing body resistance, and resisting infection and diseases.
Anti-inflammatory action: rhizoma Drynariae has antiinflammatory effect, and can be used for relieving inflammatory disease symptoms.
Improving memory and cognitive function: some studies have shown that drynaria may help improve memory and cognitive function, against decline in cognitive function.
Anti-fatigue: rhizoma Drynariae is considered to have antifatigue effect, and is effective in improving physical strength and vigor, and relieving fatigue.
Promote wound healing: rhizoma Drynariae can accelerate wound healing process, and helps to reduce swelling and promote wound repair.
Protecting liver: researches show that the drynaria rhizome has a protective effect on the liver and can help to reduce the risks of diseases such as hepatitis and the like.
Anti-aging: because of its antioxidant properties, drynaria is considered to have an effect against aging, helping to maintain youthful and healthy skin.
Chinese angelica, (Angelica sinensis) is an important Chinese medicinal material and is commonly used in Chinese medicinal preparations and Chinese medicinal formulas. Angelica has various effects and medicinal values, and the following are some main effects and uses:
replenishing blood and nourishing yin: angelica is widely used in traditional Chinese medicine as a medicinal material for nourishing blood and qi and nourishing yin. It is helpful for improving anemia symptoms, increasing hemoglobin level, and relieving asthenia and debilitation.
Conditioning female health: angelica is widely used for health care of women, especially in the treatment of menoxenia, dysmenorrhea and climacteric syndrome. It can balance female hormone and relieve menstrual discomfort.
Promote circulation: the Chinese angelica has the function of dilating blood vessels, is beneficial to improving blood circulation and reducing the risk of cardiovascular diseases.
Anti-inflammatory action: angelica sinensis is used to treat inflammatory diseases, such as rheumatoid arthritis, to reduce pain and swelling.
Improving immunity: it can enhance the immune system and help combat infections and diseases.
Anti-aging: the angelica is rich in antioxidant substances, and helps to relieve free radical damage, thereby helping to resist aging and maintain skin health.
Digestion and health care: the Chinese angelica is helpful for relieving dyspepsia and promoting intestinal health.
Antidepressant and anxiolytic effects: some studies indicate that angelica may help to combat depression and anxiety, helping mood stabilization.
Promote wound healing: angelica is believed to help accelerate wound healing, particularly in rehabilitation after trauma or surgery.
Rhizoma corydalis (academic name: corydalis yanhusuo) is a traditional Chinese medicinal material and is commonly used in traditional Chinese medicinal formulas. Rhizoma corydalis has various effects and medicinal values, and the following are some main effects and uses:
pain relief: rhizoma corydalis is widely used for relieving pain, especially for treating chest pain, abdominal pain, headache, menstrual pain, arthritis pain and other pain symptoms in traditional Chinese medicine. It contains some alkaloids such as adenine, bar Ma Jian, etc., and has analgesic effect.
Anti-inflammatory: rhizoma corydalis has antiinflammatory effect, and can be used for relieving inflammatory disease symptoms such as rheumarthritis.
Adjusting emotion: some researches show that the Yan Hu Suoke has certain effect on resisting depression and anxiety and contributes to mood stabilization.
Promote circulation: it can help to improve blood circulation and alleviate symptoms of angina and heart disease.
Anti-platelet aggregation: rhizoma corydalis can reduce adhesion and aggregation of blood platelet, and helps prevent thrombosis.
Gastrointestinal health care: in traditional Chinese medicine, corydalis tuber is also used for alleviating gastrointestinal problems such as digestive discomfort, stomach ache and diarrhea.
Astragalus mongholicus (academic name: astragalus membranaceus) is a common Chinese medicinal material and has a long history. Astragalus has various effects and medicinal values, and the following are some main effects and uses:
immunomodulation: astragalus is widely used to enhance immune system function. It can enhance immunocyte activity, increase in vivo infection resistance, and be helpful for treating common cold, influenza and other diseases.
Anti-fatigue: astragalus membranaceus is considered to have an anti-fatigue effect, which is helpful for improving physical strength and energy and relieving fatigue.
Antioxidation: it is rich in antioxidant substances, helps to neutralize free radical in body, reduces oxidative stress, maintains cell health, and has antiaging effect.
Anti-inflammatory action: astragalus has a certain effect on resisting inflammation and can be used for relieving inflammatory disease symptoms.
Regulating blood pressure: some studies have shown that astragalus may help regulate blood pressure and lower blood pressure in hypertensive patients.
Cardiovascular health care: it can improve cardiovascular health and reduce risk of heart disease and apoplexy.
Liver protection: astragalus is considered to have a protective effect on the liver, helping to reduce the risk of diseases such as hepatitis.
Kidney protection: it can help maintain kidney health and reduce the risk of nephritis and impaired kidney function.
Regulating blood sugar: some studies have shown that astragalus may have a certain regulating effect on the blood glucose level of diabetics.
Dried rhizome of rhizoma Cibotii, a mussel family plant, rhizoma Cibotii Cibotium barometz (l.) j.sm, is black brown overall, and has obvious xylem ring. The raw materials are good for hypertrophy, solid texture, no hollow and slight golden hair. The rhizoma Cibotii tablet is suitable for patients with uniform thickness, no hair, and no hollow, and has effects in nourishing liver and kidney, eliminating rheumatism, strengthening waist and foot, and benefiting joint. For soreness and pain of waist and back, pain of knee, weakness of feet, cold-dampness, peripheral arthralgia, drowsiness, frequent urination, spermatorrhea, leucorrhea.
The dried orange peel is a common traditional Chinese medicine material and is also a edible fruit peel, and has various effects and medicinal values in the traditional Chinese medicine. The following are some of the major citrus peel effects:
stomach invigorating and digestion promoting effects: the dried orange peel is helpful for stimulating digestion and relieving stomach discomfort, and has remarkable effects especially in dyspepsia, flatulence and nausea. It can promote appetite and help stomach digest food.
Relieving cough: dried orange peel is commonly used for treating colds, sore throat and cough. It can relieve phlegm and relieve respiratory tract discomfort.
Regulating intestinal function: pericarpium Citri Reticulatae is used to relieve diarrhea and abdominal pain. It helps balance intestinal function and alleviate gastrointestinal disorders.
Sedative effect: certain ingredients in pericarpium Citri Tangerinae are believed to have sedative and anxiolytic effects, and can be used for relieving emotional stress and anxiety symptoms.
Antioxidation: the dried orange peel is rich in antioxidant substances, is favorable for neutralizing free radicals and reducing cell damage caused by oxidative stress.
Promoting blood circulation: the dried orange peel is helpful for promoting blood circulation and possibly beneficial to cardiovascular health.
Detoxification: in traditional Chinese medicine, dried orange peel is used for detoxification, especially in the case of food poisoning or toxin poisoning.
Liver protection: dried orange peel is believed to help protect liver health and reduce risk of liver disease
Radix Curcumae (school name: curcuma wenyujin), also known as Wen Yujin, wen Yu golden yellow, wen Yujin element, is a common Chinese medicinal material, is also one of plants of Zingiberaceae, and has multiple effects and medicinal value. The following are some major radix Curcumae effects:
anti-inflammatory and antioxidant: radix Curcumae contains an active ingredient called curcumine, and has strong antiinflammatory and antioxidant effects. This makes it very useful in the treatment of inflammatory diseases, arthritis and diseases related to oxidative stress.
Improving digestion: radix Curcumae is used to promote digestion and alleviate gastrointestinal problems such as gastrectasia, dyspepsia and gastralgia.
Liver protection: it may help protect the liver, alleviate the risk of liver disease, as it counteracts oxidative stress and reduces inflammation.
Antibacterial action: radix Curcumae has antibacterial and antifungal effects, and can be used for treating some infectious diseases.
Anticancer: some studies indicate that radix Curcumae may have anticancer potential against certain cancers, particularly in inhibiting tumor growth and spread.
Reducing blood sugar: radix Curcumae is believed to be helpful in regulating blood glucose levels, and may be beneficial to diabetics
Radix Angelicae Dahuricae (academic name: angelica dahurica) is a commonly used Chinese medicinal material, and is also called "radix Angelicae Dahuricae blue" or "radix Angelicae Dahuricae". It has various effects and medicinal values in traditional Chinese medicine, and the following are some main radix angelicae effects:
relieving exterior syndrome and dispelling cold: radix Angelicae Dahuricae is widely used for treating common cold, influenza and symptoms caused by wind cold, such as fever, headache, nasal obstruction and shivering. It helps to dispel cold evil and promote sweat discharge.
Pain relief: radix Angelicae Dahuricae is considered to have analgesic effect and can be used for relieving headache, migraine and neuropathic pain.
Anti-inflammatory: it contains some anti-inflammatory compounds that help reduce inflammation and swelling.
Sterilization and antibacterial: radix Angelicae Dahuricae has inhibitory effect on certain bacteria and fungi, and can be used for treating infectious diseases such as skin infection.
Clearing heat and detoxicating: in traditional Chinese medicine, radix Angelicae Dahuricae is used for clearing heat and detoxicating, especially for treating pyocutaneous disease and skin infection.
Relaxing tendons and activating collaterals: radix Angelicae Dahuricae is believed to help relieve muscle and joint pain and may be used in the treatment of rheumatoid arthritis and rheumatoid arthritis.
Phlegm eliminating and cough relieving: radix Angelicae Dahuricae is sometimes used to treat cough and excessive phlegm, and can help calm cough and clear phlegm.
Protecting liver: it is believed to help protect liver health and reduce the risk of liver disease.
Cinnamon is a common spice and herb, and has various effects and medicinal values. The following are some of the major cinnamon effects:
reducing blood sugar: one compound in cinnamon, known as cinnamaldehyde, is thought to help lower blood glucose levels and therefore may be beneficial for diabetes management. Several studies have shown that ingestion of cinnamon can increase insulin sensitivity and reduce the rate of blood glucose rise.
Anti-inflammatory: cinnamon has anti-inflammatory effects and can help reduce inflammatory symptoms, particularly in arthritis and other inflammatory diseases.
Antioxidation: cinnamon is rich in antioxidant substances, is helpful for neutralizing free radicals and reducing cell damage caused by oxidative stress.
Antibacterial and antifungal: cinnamon has powerful antibacterial and antifungal effects, and can be used to treat infections, such as oral and fungal infections.
Improving cardiovascular health: cinnamon may help to reduce cholesterol levels, improve cardiovascular health, and reduce heart disease risk.
Help digestion: cinnamon can promote digestion and alleviate gastrointestinal discomfort such as bloating, dyspepsia and gastralgia.
Improving memory and cognitive function: some studies indicate that components in cinnamon may contribute to improving memory and cognitive function.
Anticancer potential: some preliminary studies suggest that cinnamon may have anticancer potential for certain cancers, particularly in inhibiting tumor growth and spread.
Dipsacus asperoides is root of Dipsacus asperoides of Dipsacaceae. The surface is tan or grey brown, has a plurality of obvious and distorted longitudinal wrinkles and grooves, and can see transverse long skin pores and a few fibrous root marks. Slightly soft, and hardens after long-term drying. The skin is easy to break, the section is uneven, the skin is greenish brown or light brown, and the wood is greenish yellow and is in radial pattern. Slightly fragrant, bitter, slightly sweet and astringent. It is indicated for soreness of waist and back, weakness of foot and knee, metrorrhagia, metrostaxis, leukorrhagia, spermatorrhea, traumatic injury, golden sore, anal fistula, carbuncle, abscess, sore and swelling.
Achyranthes, also known as (achyranthes) cortex, has a reddish or earthy yellow skin, has fine longitudinal wrinkles, has transverse long skin holes and few fibrous root marks. It is hard and slightly tough. Broken cutin has most of acid points formed by vascular bundles, has yellowish white wood core in the center, has special smell, is slightly sweet and astringent in taste, has the effects of tonifying liver and kidney, promoting tendons and bones and the like, and can be used for improving and treating lumbago and skelalgia of patients with long-term nephropathy or poor liver and kidney condition, and no matter the lumbago and skelalgia causes are kidney deficiency, rheumatism or traumatic injury; the achyranthes root can reduce the blood viscosity, accelerate the blood flow, accelerate the animal blood coagulation and avoid or relieve internal bleeding caused by the damage of blood vessels; achyranthes root has the effect of guiding blood downwards, and can regulate and treat fire and heat symptoms of the body through the blood downwards guiding scheme of achyranthes root, such as toothache. In addition, the achyranthes root has good conditioning and treating effects on sores of the mouth and tongue, gum swelling and pain, unfavorable bones and muscles and osteoporosis.
Radix Angelicae Pubescentis (school name: achyranthes bidentata) is a commonly used Chinese medicinal material, and is also called "Gedan" or "Yi He". It has various effects and medicinal values in traditional Chinese medicine, and the following are some main effects of radix angelicae pubescentis:
dispelling wind-dampness, promoting blood circulation and removing blood stasis: radix Angelicae Pubescentis is widely used in the treatment of rheumatic diseases such as rheumatic arthritis and rheumatoid arthritis. It helps to relieve joint and muscle pain, promote blood circulation, and relieve blood stasis.
Strengthening tendons and bones: it is believed to help strengthen bones and joints, and may be used in the adjuvant treatment of fracture healing and osteoporosis.
Lowering blood pressure: radix Angelicae Pubescentis is used for treating hypertension, and may help to reduce blood pressure level.
Anti-inflammatory: it has certain anti-inflammatory effect, and can be used for treating inflammatory diseases.
Promoting urination: radix Angelicae Pubescentis can promote urine excretion, and is helpful for removing excessive water and waste in vivo.
A method of preparing a pharmaceutical combination of example 1 comprising the steps of:
s1, cleaning traditional Chinese medicinal materials; cleaning, airing and impurity removing treatment are carried out on the raw materials;
s2, cutting the traditional Chinese medicinal materials into proper shapes and sizes, wherein the cutting is beneficial to improving the efficacy of the traditional Chinese medicinal materials and facilitating the processing;
s3, sterilizing: sterilizing and removing microorganisms in the raw materials; ensuring sterility of Chinese medicinal materials is important to prevent spoilage, pollution and deterioration caused by microorganism; the risk of microorganism infection in the preparation process of the subsequent preparation is reduced;
s4, airing: airing the traditional Chinese medicine raw materials; solar insolation can be used to improve the taste or effect, and the control time is controlled within 3 hours;
s5, freeze grinding: the traditional Chinese medicine raw materials are frozen and then ground, and for part of traditional Chinese medicine materials, the traditional Chinese medicine raw materials are required to be ground into powder so as to prolong the storage life, and then the traditional Chinese medicine raw materials are frozen and ground by using a freezing grinder. Freezing is helpful for maintaining stability and activity of effective components in the medicinal materials, and avoiding overheating during grinding;
s6, sieving: for the ground traditional Chinese medicine powder, a screen can be used for screening to remove coarse powder and impurities, and fine powder is reserved;
s7, properly packaging to keep the quality and avoid being affected with damp or polluted, and storing the product in a place with good dryness, shade and ventilation;
and S8, mixing the obtained various powders together to obtain the composition.
Further, the cleaning and soaking time in the step S1 is 12 hours.
Further, the sterilization mode in the step S3 is steam sterilization, and the mixture is kept stand for 6 to 15 minutes in a steam environment; the mild nature of steam sterilization is helpful for maintaining chemical components and drug effects of the traditional Chinese medicine raw materials; steam sterilization is less likely to cause degradation or inactivation of chemical components of the medicinal materials; also helps to reduce exogenous contamination of the raw materials during the manufacturing and packaging process, as the steam can kill microorganisms in the air and prevent contamination of the raw materials when it contacts the raw materials.
Further, the S5 freeze milling is performed for 5 minutes to 15 minutes by using a freeze mill; until the blocky medicinal materials become fine powder.
Further, the powder selected in S6 is 120 mesh.
Further, the composition is prepared into any one of a tablet, a pill and a capsule.
Usage and dosage: various fractures and dislocation: 2-4g (about 10-20 granules) at a time, 3 times a day; necrosis of femoral head: 4-6g (about 20-30 granules) for one time, 2 times a day, and warm boiled water; in addition, yellow wine can be used for concocting fracture or hematoma; convenient administration and definite curative effect.
With consent from the patient himself, 2 patient cases were published. With protection of patient personal information, the examination results will now be described in detail as follows:
medical records one:
some Huo, men, 29 years old, farmers, shin-fibula middle aged fracture for more than 4 months, facial weakness and luteal weakness
Complaints: poor appetite, dreaminess, weakness and fatigue
Past history of: weak body, deficiency of both qi and blood, unfavorable venation and malnutrition of tendons and bones
The current medical history: old fracture of middle section of left tibiofibula and X-ray film show: no callus is generated, and the patient is treated before the fracture is healed due to deficiency of both qi and blood
Diagnosis: western medicine: delayed union of fracture
Traditional Chinese medicine: qi and blood deficiency failing to nourish the tendons and bones
Prescription: bone growing pill 250g
Efficacy: blood replenishing, blood activating, yang warming and tonifying, and tendons and bones strengthening
Dosage for administration: 20 granules (4 g) 3 times daily
The administration method comprises the following steps: warm boiled water infusion garment
Doctor's advice: re-diagnosis after one month
The patient has ruddy complexion, increased appetite and X-ray film shows that the fracture has a small amount of callus formation, and the patient is prescribed to continue taking the osteogenesis pill, and the patient is re-diagnosed after 2 months, so that the fracture healing is good.
And a second medical record:
king, men, 7 years old, students, right forearm with a fall injury in the middle lower segment, 1 hour to diagnose
Complaints: injury, swelling, pain and deformity of the right forearm
Past history of: normal symptoms of each item
The current medical history: right forearm swelling, pain, deformity, X-ray film: distal radius of right ulna double fracture
Diagnosis: western medicine: distal ulna-radius double fracture
Traditional Chinese medicine: ulna fracture (fracture disease)
Prescription: bone growing pill, 50g
Efficacy: promoting blood circulation, replenishing blood, breaking blood, removing blood stasis, and reuniting bone
Dosage for administration: 2g once and 2 times a day (external application of traditional Chinese medicine and external fixation of small splint gypsum)
The administration method comprises the following steps: warm boiled water infusion garment
Doctor's advice: after 1 week, the patient is re-diagnosed, the swelling is basically resolved, the pain is relieved, the patient is prescribed to take the osteogenesis pill orally, and the external fixation of the splint and the plaster is adjusted
Review after 1 month: good fracture healing
Thus far, the technical solution of the present invention has been described in connection with the preferred embodiments, but it is easily understood by those skilled in the art that the scope of protection of the present invention is not limited to these specific embodiments. Equivalent modifications and substitutions for related technical features may be made by those skilled in the art without departing from the principles of the present invention, and such modifications and substitutions will be within the scope of the present invention.
The foregoing description is only of the preferred embodiments of the invention and is not intended to limit the invention; various modifications and variations of the present invention will be apparent to those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (9)
1. A traditional Chinese medicine composition for treating bone injury is characterized by comprising the following components: radix Notoginseng, eupolyphaga Seu Steleophaga, rhizoma Drynariae, radix Angelicae sinensis, rhizoma corydalis, radix astragali, rhizoma Cibotii, pericarpium Citri Tangerinae, radix Curcumae, radix Angelicae Dahuricae, cortex Cinnamomi, radix Dipsaci, achyranthis radix, and radix Angelicae Pubescentis.
2. The traditional Chinese medicine composition for treating bone injury according to claim 1, which is characterized by comprising the following components in parts by weight: 2-10 parts of wide pseudo-ginseng, 1-6 parts of ground beetle, 2-7 parts of rhizoma drynariae, 1.5-6.5 parts of Chinese angelica, 1-9 parts of rhizoma corydalis, 5-15 parts of astragalus mongholicus, 1-7.5 parts of rhizoma cibotii, 1-5 parts of dried orange peel, 3-5 parts of radix curcumae, 1.5-5 parts of radix angelicae, 3-9 parts of cinnamon, 2.5-6 parts of radix dipsaci, 4-8 parts of achyranthis bidentatae and 1-6 parts of radix angelicae pubescentis.
3. The traditional Chinese medicine composition for treating bone injury according to claim 2, which is characterized by comprising the following components in parts by weight: 5 parts of wide pseudo-ginseng, 3 parts of ground beetle, 3 parts of rhizoma drynariae, 3 parts of Chinese angelica, 3 parts of rhizoma corydalis, 10 parts of astragalus, 3 parts of rhizoma cibotii, 3 parts of dried orange peel, 3 parts of radix curcumae, 3 parts of radix angelicae, 3 parts of cinnamon, 3 parts of dipsacus root, 5 parts of achyranthes and 3 parts of radix angelicae pubescentis.
4. A method for preparing a traditional Chinese medicine composition for treating bone injury according to any one of claims 1 to 3, comprising the following steps:
s1, cleaning: the Chinese medicinal materials are required to be cleaned and soaked;
s2, cutting: cutting the Chinese medicinal materials into proper shape and size;
s3, sterilizing: sterilizing and removing microorganisms in the raw materials;
s4, airing: airing the traditional Chinese medicine raw materials;
s5, freeze grinding: freezing the traditional Chinese medicine raw materials, and grinding;
s6, sieving: screening the ground traditional Chinese medicine powder;
s7, packaging: proper packaging is carried out to avoid being affected with damp or polluted;
and S8, uniformly mixing the weighed various powders according to a formula to obtain the composition.
5. The method for preparing a Chinese medicinal composition for treating bone injury according to claim 4, wherein the washing soaking time in S1 is 12 hours.
6. The method for preparing a Chinese medicinal composition for treating bone injury according to claim 4, wherein the sterilization mode in S3 is steam sterilization, and the composition is left to stand for 6 to 15 minutes in a steam environment.
7. The method for preparing a pharmaceutical composition for treating bone injury according to claim 4, wherein the S5 cold milling is performed using a freeze mill for 5 to 15 minutes.
8. The method for preparing a pharmaceutical composition for treating bone injury according to claim 4, wherein the powder selected in S6 is 120 mesh.
9. A Chinese medicinal composition for treating bone injury according to any one of claims 1-3, wherein said composition is formulated in the form of any one of a tablet, a pill, and a capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311371921.4A CN117180389A (en) | 2023-10-23 | 2023-10-23 | Traditional Chinese medicine composition for treating bone injury |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311371921.4A CN117180389A (en) | 2023-10-23 | 2023-10-23 | Traditional Chinese medicine composition for treating bone injury |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117180389A true CN117180389A (en) | 2023-12-08 |
Family
ID=89003602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311371921.4A Pending CN117180389A (en) | 2023-10-23 | 2023-10-23 | Traditional Chinese medicine composition for treating bone injury |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN117180389A (en) |
-
2023
- 2023-10-23 CN CN202311371921.4A patent/CN117180389A/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107320555A (en) | A kind of pharmaceutical composition with antifatigue effect and its production and use | |
| CN110859904A (en) | Gorgon fruit oral liquid capable of tonifying kidney, supporting yang, tonifying qi and producing sperm | |
| CN117180389A (en) | Traditional Chinese medicine composition for treating bone injury | |
| CN101239162B (en) | Traditional Chinese medicine composition for treating stomach disease | |
| CN101518579B (en) | Pressure stabilizing deoppilant and preparation process | |
| CN105031170A (en) | Healthcare foot bath powder and preparing method thereof | |
| CN107753670A (en) | A kind of traditional Chinese medicinal ointment for treating burn and scald | |
| CN117357608B (en) | External application medicine for treating traumatic injury and fracture and tendon injury | |
| CN107617081A (en) | The Chinese medicine composition and its preparation and preparation method of a kind of hair growth | |
| CN107789607A (en) | A kind of Chinese medicine composition for being used to treat cold blood stasis | |
| CN103007238B (en) | Traditional Chinese medicine composition for treating decubitus ulcers | |
| CN111568986B (en) | Chinese medicinal oral prescription for setting fracture, external ointment and preparation method thereof | |
| CN106924673A (en) | A kind of Chinese medicine composition for treating osteoproliferation and its medicament preparation method | |
| CN101513515A (en) | Chinese patent drug for treatment of lung cancer | |
| CN106266704A (en) | The Chinese medicine composition for the treatment of gastroenteritis and preparation method | |
| CN105343474A (en) | Capsules for treating male climacteric syndromes and preparation method | |
| CN104055968A (en) | Aerosol with effects of promoting blood circulation to remove meridian obstruction for postoperative patients | |
| CN104840814A (en) | Traditional Chinese medicine combination for treating senile femoral head necrosis | |
| CN103798720A (en) | Eucommia bark hot-pot flavoring capable of strengthening muscles and bones and production method thereof | |
| CN103263543B (en) | Care solution for postoperative fumigation treatment on fracture patient | |
| CN111658715A (en) | Traditional Chinese medicine preparation for treating rheumatism and preparation method thereof | |
| CN114748592A (en) | Traditional Chinese medicine compound composition with effects of tonifying kidney, securing essence, tonifying qi and nourishing yin | |
| CN103800874A (en) | Medicinal composition for treating extremity function disturbance due to stroke hemiplegia by fumigation therapy | |
| CN114632074A (en) | Calculus-removing ointment for treating gallstone | |
| CN103861062A (en) | Traditional Chinese medicine composition for treating rheumatoid diseases and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |