CN117122528A - 一种美白淡斑组合物的制备方法 - Google Patents
一种美白淡斑组合物的制备方法 Download PDFInfo
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- CN117122528A CN117122528A CN202210535858.2A CN202210535858A CN117122528A CN 117122528 A CN117122528 A CN 117122528A CN 202210535858 A CN202210535858 A CN 202210535858A CN 117122528 A CN117122528 A CN 117122528A
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- whitening
- spot
- mixture
- stirring
- fading
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Abstract
本发明公开了美白淡斑组合物的制备方法，通过多种美白淡斑活性物相互协同的作用,能有效的抑制酪氨酸酶的活性,高效清除氧自由基,防止黑色素的产生,分解淡化已经形成的黑色素，同时能够调节人体的内分泌系统,修复由于激素等化学成分对皮肤造成的损伤，从而达到全面快速、标本兼治的效果。该复合物能够解决美白活性成分易分解、易氧化、易变色等问题,降低了光线、热对功效成分的影响。该美白淡斑组合物形式为乳液、精华液、凝胶、膏霜和水凝胶贴片中的一种或多种。还可以借助美容仪、超声、红外、电脉冲、中低频等仪器辅助导入皮肤，相对于直接涂敷，使用效果更佳。
Description
技术领域
本发明涉及美容技术领域，具体为一种美白淡斑组合物的制备方法。
背景技术
随着生活水平的提高,美容护肤越来越受到重视,人们对护肤品的功效与安全的要求也越来越高，由于遗传、紫外线照射或其他原因引起的面部色斑、面部粗糙也成为困扰各个年龄层人群的问题。色斑是由于皮肤黑色素的增加而形成的一种常见面部呈褐色或黑色素沉着性、损容性的皮肤疾病，多发于面颊和前额部位,日晒后加重,多见于女性。新陈代谢不正常、肌肤裸露在强烈的紫外线下、精神上受到压力、错误使用化妆品等原因,都会使斑的颜色加深。色斑包括雀斑、黑斑、黄褐斑和老年斑等,色斑的存在轻则只是影响美观,重者则会给患者的身心健康带来很大的影响,从而影响其正常生活，市面上美白活性成分很多,但有一定的缺点。一些美白活性成分会导致皮肤出现刺激、过敏等现象;多数美白活性成分不稳定,易氧化变质、变色而失去美白作用;有些美白活性成分的表皮渗透性差,难以透过角质层进入皮肤基底层发挥作用。
发明内容
（一）解决的技术问题
针对现有技术的不足，本发明提供了一种美白淡斑组合物的制备方法，具备有效的抑制酪氨酸酶的活性等优点，解决了美白活性成分易分解、易氧化、易变色的问题。
（二）技术方案
为实现上述解决美白活性成分易分解、易氧化、易变色目的，本发明提供如下技术方案：
一种美白淡斑组合物的制备方法，其特征在于，包括以下步骤：
S1、原料分配
以化妆品的重量为基准，所述美白淡斑组合物由凝血酸、烟酰胺、间苯二酚和九肽按照1～3:1～5:0.1～1:0.1～2的重量比组成，并在美白淡斑组合物中加入0.1～3重量%透明质酸钠，加入0.1～1重量%红没药醇，改善皮肤炎症，加入0.1～1重量%甘草酸二钾。
S2、原料搅拌
加入重量百分比为3～7％的甘油，搅拌15 ～20min，均匀分散后，得到混合物A，在混合物A中，加入重量百分比为30-90％的水，在50～60r/min下搅拌，直到所有组分混合均匀后，按配比分别加入重量百分比为1～2%的泛醇、1～3%的海藻糖、0.5～2%的积雪草苷、1～5%的北美金缕梅提取物、0.1～0.3％的氯苯甘醚、0.3～ 0.5％苯氧乙醇和0.1～0.2％香精，搅拌30～50min后，得到混合物B。
S3、原料提取
加入重量百分比为3～10％的甘油、1～5%丁二醇、0.1～0.6%的黄原胶，搅拌15～20min，均匀分散后，得到混合物A，按配比分别加入重量百分比为30～90％的水、0.1～0.6％的卡波940，分散均匀后，50～60r/min搅拌，直到完全均匀混合，接着加入重量百分比为1～2%的泛醇、1～3%的海藻糖、0.5～2%的积雪草苷、1～5%的北美金缕提取物、0 .1～ 0.8％的三乙醇胺，搅拌均匀后，得到混合物B。
S4、原料加热
按配比分别加入重量百分比为1～3％的硬脂酸甘油酯、3～7％辛酸/癸酸甘油三酯、0.3～2%的硬脂酸、0.5～2%的鲸蜡醇、5～6％棕榈酸异丙酯，加热搅拌分散均匀后，得到混合物C，将混合物A、B、C高温均质搅拌15～20min，再按配比分别加入重量百分比为0.1～0.3％的氯苯甘醚、0.3～0.5％苯氧乙醇和0.1～0.2％香精，搅拌30～50min后，得到混合物D。
S5、原料固化
按配比分别称取原料中的组分，搅15～20min，均匀分散后，得到混合物A，分别将重量百分比为6～7％的聚丙烯酸钠、0.1～0.25％的甘羟铝和0.1～0.2％的乙二胺四乙酸二钠加入重量百分比为20～25％的甘油中。
优选的，所述接着加入重量百分比为0.25～0.3％的酒石酸、0.1～0.3％的氯苯甘醚、0.3～0.5％的苯氧乙醇、0.1～0.2％的香精、5～65％的水和所述混合物A，真空搅拌均匀后，涂布在衬材上，经过交联固化后，制成水凝胶贴片。
优选的，所述美白淡斑组合物形式为乳液、精华液、凝胶、膏霜和水凝胶贴片中的一种或多种。
优选的，所述检验混合物B的pH、耐热、耐寒和细菌数量指标，均符合标准后，出料，静置和灌装，得到精华液。
优选的，所述精华液使用美容仪、超声、红外、电脉冲、中低频仪器中的一种或多种辅助导入皮肤。
优选的，所述衬材为复合铝箔、聚乙烯、聚氯乙烯、聚丙烯、聚苯乙烯、聚酯、聚对苯二甲酸乙二酯和无纺布中的一种或多种。
优选的，所述水凝胶贴片贴在皮肤表面后，使用美容仪、超声、红外、电脉冲、中低频仪器中的一种或多种辅助导入皮肤。
（三）有益效果
与现有技术相比，本发明提供了一种美白淡斑组合物的制备方法，具备以下有益效果：
1、该美白淡斑组合物的制备方法，通过多种美白淡斑活性物相互协同的作用,能有效的抑制酪氨酸酶的活性,高效清除氧自由基,防止黑色素的产生,分解淡化已经形成的黑色素，同时能够调节人体的内分泌系统,修复由于激素等化学成分对皮肤造成的损伤，从而达到全面快速、标本兼治的效果。该复合物能够解决美白活性成分易分解、易氧化、易变色等问题,降低了光线、热对功效成分的影响。该美白淡斑组合物形式为乳液、精华液、凝胶、膏霜和水凝胶贴片中的一种或多种。还可以借助美容仪、超声、红外、电脉冲、中低频等仪器辅助导入皮肤，相对于直接涂敷，使用效果更佳。
2、该美白淡斑组合物的制备方法，通过提供的美白淡斑组合，将不同作用原理，影响不同代谢通路的功效组分复配，从而起到见效快、适用广、效果持久的美白淡斑作用。
具体实施方式
下面将结合本发明的实施例，对本发明实施例中的技术方案进行清楚、完整地描述，显然，所描述的实施例仅仅是本发明一部分实施例，而不是全部的实施例。基于本发明中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本发明保护的范围。
一种美白淡斑组合物的制备方法，其特征在于，包括以下步骤：
S1、原料分配
以化妆品的重量为基准，所述美白淡斑组合物由凝血酸、烟酰胺、间苯二酚和九肽按照1～3:1～5:0.1～1:0.1～2的重量比组成，并在美白淡斑组合物中加入0.1～3重量%透明质酸钠，加入0.1～1重量%红没药醇，改善皮肤炎症，加入0.1～1重量%甘草酸二钾。
S2、原料搅拌
加入重量百分比为3～7％的甘油，搅拌15 ～20min，均匀分散后，得到混合物A，在混合物A中，加入重量百分比为30-90％的水，在50～60r/min下搅拌，直到所有组分混合均匀后，按配比分别加入重量百分比为1～2%的泛醇、1～3%的海藻糖、0.5～2%的积雪草苷、1～5%的北美金缕梅提取物、0.1～0.3％的氯苯甘醚、0.3～ 0.5％苯氧乙醇和0.1～0.2％香精，搅拌30～50min后，得到混合物B。
S3、原料提取
加入重量百分比为3～10％的甘油、1～5%丁二醇、0.1～0.6%的黄原胶，搅拌15～20min，均匀分散后，得到混合物A，按配比分别加入重量百分比为30～90％的水、0.1～0.6％的卡波940，分散均匀后，50～60r/min搅拌，直到完全均匀混合，接着加入重量百分比为1～2%的泛醇、1～3%的海藻糖、0.5～2%的积雪草苷、1～5%的北美金缕提取物、0 .1～ 0.8％的三乙醇胺，搅拌均匀后，得到混合物B。
S4、原料加热
按配比分别加入重量百分比为1～3％的硬脂酸甘油酯、3～7％辛酸/癸酸甘油三酯、0.3～2%的硬脂酸、0.5～2%的鲸蜡醇、5～6％棕榈酸异丙酯，加热搅拌分散均匀后，得到混合物C，将混合物A、B、C高温均质搅拌15～20min，再按配比分别加入重量百分比为0.1～0.3％的氯苯甘醚、0.3～0.5％苯氧乙醇和0.1～0.2％香精，搅拌30～50min后，得到混合物D。
S5、原料固化
按配比分别称取原料中的组分，搅15～20min，均匀分散后，得到混合物A，分别将重量百分比为6～7％的聚丙烯酸钠、0.1～0.25％的甘羟铝和0.1～0.2％的乙二胺四乙酸二钠加入重量百分比为20～25％的甘油中。
通过加入重量百分比为0.25～0.3％的酒石酸、0.1～0.3％的氯苯甘醚、0.3～0.5％的苯氧乙醇、0.1～0.2％的香精、5～65％的水和所述混合物A，真空搅拌均匀后，涂布在衬材上，经过交联固化后，制成水凝胶贴片，美白淡斑组合物形式为乳液、精华液、凝胶、膏霜和水凝胶贴片中的一种或多种，检验混合物B的pH、耐热、耐寒和细菌数量指标，均符合标准后，出料，静置和灌装，得到精华液，精华液使用美容仪、超声、红外、电脉冲、中低频仪器中的一种或多种辅助导入皮肤，衬材为复合铝箔、聚乙烯、聚氯乙烯、聚丙烯、聚苯乙烯、聚酯、聚对苯二甲酸乙二酯和无纺布中的一种或多种，水凝胶贴片贴在皮肤表面后，使用美容仪、超声、红外、电脉冲、中低频仪器中的一种或多种辅助导入皮肤。
由于黑色素的生成主要是受酪氨酸酶活性控制的氧化链过程,所以美白剂通常通过三种途径达到目的:一部分是通过抑制酪氨酸酶活性或阻断氧化链来防止黑色素生成。一部分美白产品可以通过还原黑色素达到美白淡斑的效果。一部分美白产品可以通过抑制已形成的黑色素转移到表皮细胞,促进含黑色素的角质细胞脱落来达到美白肌肤作用。
尽管已经示出和描述了本发明的实施例，对于本领域的普通技术人员而言，可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型，本发明的范围由所附权利要求及其等同物限定。
Claims (7)
1.一种美白淡斑组合物的制备方法，其特征在于，包括以下步骤：S1、原料分配：以化妆品的重量为基准，所述美白淡斑组合物由凝血酸、烟酰胺、间苯二酚和九肽按照1～3:1～5:0.1～1:0.1～2的重量比组成，并在美白淡斑组合物中加入0.1～3重量%透明质酸钠，加入0.1～1重量%红没药醇，改善皮肤炎症，加入0.1～1重量%甘草酸二钾，S2、原料搅拌：加入重量百分比为3～7％的甘油，搅拌15 ～20min，均匀分散后，得到混合物A，在混合物A中，加入重量百分比为30-90％的水，在50～60r/min下搅拌，直到所有组分混合均匀后，按配比分别加入重量百分比为1～2%的泛醇、1～3%的海藻糖、0.5～2%的积雪草苷、1～5%的北美金缕梅提取物、0.1～0.3％的氯苯甘醚、0.3～ 0.5％苯氧乙醇和0.1～0.2％香精，搅拌30～50min后，得到混合物B，S3、原料提取：加入重量百分比为3～10％的甘油、1～5%丁二醇、0.1～0.6%的黄原胶，搅拌15～20min，均匀分散后，得到混合物A，按配比分别加入重量百分比为30～90％的水、0.1～0.6％的卡波940，分散均匀后，50～60r/min搅拌，直到完全均匀混合，接着加入重量百分比为1～2%的泛醇、1～3%的海藻糖、0.5～2%的积雪草苷、1～5%的北美金缕提取物、0 .1～ 0 .8％的三乙醇胺，搅拌均匀后，得到混合物B，S4、原料加热：按配比分别加入重量百分比为1～3％的硬脂酸甘油酯、3～7％辛酸/癸酸甘油三酯、0.3～2%的硬脂酸、0.5～2%的鲸蜡醇、5～6％棕榈酸异丙酯，加热搅拌分散均匀后，得到混合物C，将混合物A、B、C高温均质搅拌15～20min，再按配比分别加入重量百分比为0.1～0.3％的氯苯甘醚、0.3～0.5％苯氧乙醇和0.1～0.2％香精，搅拌30～50min后，得到混合物D，S5、原料固化：按配比分别称取原料中的组分，搅15～20min，均匀分散后，得到混合物A，分别将重量百分比为6～7％的聚丙烯酸钠、0.1～0.25％的甘羟铝和0.1～0.2％的乙二胺四乙酸二钠加入重量百分比为20～25％的甘油中。
2.根据权利要求1所述的一种美白淡斑组合物的制备方法，其特征在于，所述接着加入重量百分比为0.25～0.3％的酒石酸、0.1～0.3％的氯苯甘醚、0.3～0.5％的苯氧乙醇、0.1～0.2％的香精、5～65％的水和所述混合物A，真空搅拌均匀后，涂布在衬材上，经过交联固化后，制成水凝胶贴片。
3.根据权利要求1所述的一种美白淡斑组合物的制备方法，其特征在于，所述美白淡斑组合物形式为乳液、精华液、凝胶、膏霜和水凝胶贴片中的一种或多种。
4.根据权利要求1所述的一种美白淡斑组合物的制备方法，其特征在于，所述检验混合物B的pH、耐热、耐寒和细菌数量指标，均符合标准后，出料，静置和灌装，得到精华液。
5.根据权利要求1所述的一种美白淡斑组合物的制备方法，其特征在于，所述精华液使用美容仪、超声、红外、电脉冲、中低频仪器中的一种或多种辅助导入皮肤。
6.根据权利要求1所述的一种美白淡斑组合物的制备方法，其特征在于，所述衬材为复合铝箔、聚乙烯、聚氯乙烯、聚丙烯、聚苯乙烯、聚酯、聚对苯二甲酸乙二酯和无纺布中的一种或多种。
7.根据权利要求1所述的一种美白淡斑组合物的制备方法，其特征在于，所述水凝胶贴片贴在皮肤表面后，使用美容仪、超声、红外、电脉冲、中低频仪器中的一种或多种辅助导入皮肤。
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