CN117100601A - Dispensing system and method for preparing indissolvable drugs - Google Patents
Dispensing system and method for preparing indissolvable drugs Download PDFInfo
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- CN117100601A CN117100601A CN202311209711.5A CN202311209711A CN117100601A CN 117100601 A CN117100601 A CN 117100601A CN 202311209711 A CN202311209711 A CN 202311209711A CN 117100601 A CN117100601 A CN 117100601A
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- 239000003814 drug Substances 0.000 title claims abstract description 43
- 229940079593 drug Drugs 0.000 title claims abstract description 26
- 238000000034 method Methods 0.000 title claims abstract description 17
- 239000002904 solvent Substances 0.000 claims abstract description 154
- 229930182555 Penicillin Natural products 0.000 claims abstract description 63
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims abstract description 63
- 229940049954 penicillin Drugs 0.000 claims abstract description 63
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 48
- 239000007788 liquid Substances 0.000 claims abstract description 26
- 230000010355 oscillation Effects 0.000 claims abstract description 24
- 238000002347 injection Methods 0.000 claims abstract description 19
- 239000007924 injection Substances 0.000 claims abstract description 19
- 230000005540 biological transmission Effects 0.000 abstract description 4
- 238000004090 dissolution Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000009514 concussion Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B25—HAND TOOLS; PORTABLE POWER-DRIVEN TOOLS; MANIPULATORS
- B25J—MANIPULATORS; CHAMBERS PROVIDED WITH MANIPULATION DEVICES
- B25J9/00—Programme-controlled manipulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/16—Holders for containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/2017—Piercing means having three or more piercing ends
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2048—Connecting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/20—Mixing the contents of independent containers, e.g. test tubes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/40—Mounting or supporting mixing devices or receptacles; Clamping or holding arrangements therefor
- B01F35/42—Clamping or holding arrangements for mounting receptacles on mixing devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/22—Mixing of ingredients for pharmaceutical or medical compositions
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Mechanical Engineering (AREA)
- Robotics (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Abstract
The invention discloses a dispensing system and a dispensing method for preparing indissolvable drugs, wherein the dispensing system comprises four parts of an oscillation module, a public solvent injection module, an independent solvent split charging module and a mechanical action module, wherein the public solvent injection module is used for injecting liquid in a public solvent into a penicillin bottle in the oscillation module, and the independent solvent split charging module is used for injecting a medicament in the oscillated penicillin bottle into an independently packaged solvent bag. Multiple bottles can vibrate simultaneously, so that the dispensing speed of indissolvable medicaments is increased; meanwhile, the automation of medicament transmission and the automation of penicillin bottle use and transmission are realized through the cooperation of the mechanical action module, the peristaltic pump and the clamping jaw, and the efficiency is higher.
Description
Technical Field
The invention relates to the field of dispensing equipment, in particular to a dispensing system and a dispensing method for preparing indissolvable drugs.
Background
In clinic, when medical staff replace the penicillin bottle to manually dispense medicines, the medical staff needs to go through the steps of inserting needles, drawing liquid, inserting needles, injecting liquid, shaking liquid, drawing mixed liquid, inserting the liquid medicine bottle, injecting liquid and the like, and the whole medicine dispensing process is complex.
In the prior art, in order to save the time of shaking liquid and improve the efficiency of shaking liquid, the Chinese patent application No. 202110739240.3 discloses a shaking medicine mixing device for dispensing medicine, but only one procedure of mixing medicine is finished, and the whole process of dispensing medicine cannot be realized, so that a dispensing system for replacing manual dispensing medicine and having high efficiency is needed.
Disclosure of Invention
A first object of the present invention is to provide a dispensing system for dispensing poorly soluble drugs that has the advantages of automated dispensing, high efficiency and good mixing effect.
The technical aim of the invention is realized by the following technical scheme: a dispensing system for preparing indissolvable medicines comprises a frame body including
The vibration module is arranged on the frame body and comprises a loading disc, a placing frame and a vibration unit, the placing frame is arranged on the loading disc, a placing hole for arranging a penicillin bottle is formed in the placing frame, and the vibration unit is connected with the loading disc;
the public solvent injection module comprises a first peristaltic pump, a first needle head unit, a second needle head unit and a public solvent, wherein the puncture end of the first needle head unit is communicated with the public solvent, the communication end of the first needle head unit is communicated with the communication end of the second needle head unit, the second needle head unit is movably connected to the frame body, and the first peristaltic pump is connected between the first needle head unit and the second needle head unit;
the independent solvent split charging module comprises a solvent rotating frame, a second peristaltic pump, a third needle unit, a fourth needle unit and a needle moving unit, wherein a clamping part for clamping a solvent bag opening is arranged on the solvent rotating frame, a puncture end of the third needle unit is connected to the frame body, a communication end of the third needle unit is communicated with a communication end of the fourth needle unit, the fourth needle unit is arranged on the needle moving unit, the second peristaltic pump is arranged between the third needle unit and the fourth needle unit, the puncture end of the fourth needle unit faces towards the solvent bag opening, the needle moving unit drives the fourth needle unit to move away from or puncture the solvent bag opening, and the solvent rotating frame drives each solvent bag opening to move into a position corresponding to the puncture end of the fourth needle unit;
the mechanical action module comprises clamping jaws, the mechanical action module drives the clamping jaws to clamp the second needle head unit to move and puncture the bottle mouth of the penicillin bottle, and the mechanical action module drives the clamping jaws to clamp the penicillin bottle to move and puncture the puncture end of the third needle head unit.
Preferably, the oscillation module, the common solvent injection module and the independent solvent split charging module are arranged on the frame in at least two groups, and the oscillation module, the common solvent injection module and the independent solvent split charging module are arranged in a mirror image mode by taking the mechanical action module as a center.
By adopting the technical scheme, the shake liquid mixing and shake of the second group of penicillin bottles are performed in idle time, so that the working efficiency is doubled.
Preferably, the frame body is provided with a solvent placing frame, the bottom of the public solvent is provided with a hanging hole, the solvent placing frame is provided with a hanging hook matched with the hanging hole, the public solvent is inversely arranged on the solvent placing frame, and the hanging hooks are symmetrically arranged on the solvent placing frame.
By adopting the technical scheme, the public solvent is convenient for medical staff to place.
Preferably, the frame body is provided with a needle head placing frame, the second needle head unit and the third needle head unit are arranged on two sides of the needle head placing frame, the needle head placing frame is provided with a clamping hole for limiting the second needle head unit and the third needle head unit to move in the height direction, the clamping hole extends outwards to form a separation groove for the second needle head unit and the third needle head unit to enter and leave the clamping hole, the puncture end of the second needle head unit is downwards arranged on the needle head placing frame, and the puncture end of the third needle head unit is upwards arranged on the needle head placing frame.
Through adopting above-mentioned technical scheme, the syringe needle rack bears the supporting role when penicillin bottle is invertd and is pushed down simultaneously, when carrying out the centre gripping to the arm simultaneously, fixes and fixes second syringe needle unit and third syringe needle unit.
Preferably, the operation panel is arranged on the frame body, a touch screen, a start button and an emergency stop button are arranged on the outward side of the operation panel, the first peristaltic pump, the second peristaltic pump, the needle head placing frame and the solvent placing frame are all arranged at the top of the operation panel, the solvent placing frame is arranged in the middle of the top of the operation panel, the first peristaltic pump is arranged between the needle head placing frame and the solvent placing frame, and the needle head placing frame is arranged between the second peristaltic pump and the first peristaltic pump.
Through adopting above-mentioned technical scheme, the medical personnel of being convenient for operate the operation panel, the space of rational utilization frame simultaneously.
Preferably, a first hose is arranged between the first needle unit and the second needle unit, a second hose is arranged between the third needle unit and the fourth needle unit, the first hose passes through the first peristaltic pump, and the second hose passes through the second peristaltic pump.
By adopting the technical scheme, the medicament is transmitted through the hose, and the peristaltic pump drives the liquid to be transmitted between the needle units.
Preferably, the mechanical action module is a six-axis mechanical arm, the action end of the six-axis mechanical arm is connected with a finger cylinder, and the finger cylinder is connected with the clamping jaw.
By adopting the technical scheme, the movement of multiple angles and distances can be realized, and the clamping of the needle head unit and the movement of the penicillin bottle are facilitated.
Preferably, the needle moving unit comprises a lifting cylinder, an extension arm and a positioning groove, wherein the lifting cylinder is arranged at the center of the solvent rotating frame, the movable end of the lifting cylinder is connected with the extension arm, the extension arm extends to the upper side of the solvent bag mouth along the horizontal direction, the positioning groove is arranged at one end of the lifting cylinder based on the principle of the extension arm, the fourth needle unit is vertically connected in the positioning groove, and the puncture end of the fourth needle unit is vertically downwards arranged.
By adopting the technical scheme, the lifting cylinder moves the extension arm downwards in the lifting process, and the fourth needle head unit is inserted into the bag mouth position of the solvent bag.
The second object of the invention is to provide a dispensing method for dispensing poorly soluble drugs, which has the advantages of automatic dispensing, high efficiency and good mixing effect.
The technical aim of the invention is realized by the following technical scheme: a dispensing method for preparing indissolvable drugs, which comprises the following steps,
step one, uniformly placing penicillin bottles on an oscillation loading disc, reversely hanging public solvents, and uniformly placing solvent bags on a solvent rotating frame;
step two, clamping the needle, connecting the first needle unit with the second needle unit, connecting the third needle unit with the fourth needle unit, and connecting the first needle unit with the public solvent;
step three, the mechanical arm takes down the second needle head through the clamping jaw and punctures the penicillin bottle, and the peristaltic pump works to inject the public solvent into the penicillin bottle;
step four, after the liquid injection is finished, oscillating the loading disc to work, and placing the needle back by the mechanical arm through the clamping jaw;
step five, after the vibration is finished, the mechanical arm inversely moves the penicillin bottle above the puncture end of the third needle unit, the penicillin bottle is lowered to enable the third needle unit to puncture the penicillin bottle, meanwhile, the fourth needle unit is lowered to puncture the solvent bag mouth, and the peristaltic pump works to inject liquid in the penicillin bottle into the solvent bag;
step six, after the conveying is finished, the mechanical arm returns the penicillin bottles, and the steps three to six are repeated until the conveying of the liquid medicine with the number of penicillin bottles required by the single-bag solvent bag is finished;
and step seven, lifting the fourth needle head unit, rotating the solvent rotating frame, rotating the next bag of solvent bag to the lower part of the fourth needle head unit, and continuing dispensing until the configuration of the penicillin bottle or the solvent bag is completed.
Preferably, in the fourth step, the mechanical arm may perform the second to fourth steps on other stations during the vibration loading disc work.
Through adopting above-mentioned technical scheme, utilize concussion time, carry out the process of second station, improve the efficiency of dispensing.
In summary, the system can simultaneously meet the requirements of configuration and oscillation of a plurality of indissolvable drugs, quickens drug dissolution, carries out drug configuration after dissolution, and can realize simultaneous oscillation of a plurality of bottles through the placing rack and the oscillation unit at the bottom, thereby quickening the dispensing speed of indissolvable drugs; meanwhile, the automation of medicament transmission and the automation of penicillin bottle use and transmission are realized through the cooperation of the mechanical action module, the peristaltic pump and the clamping jaw, and the efficiency is higher.
Drawings
FIG. 1 is a schematic structural view of an embodiment;
FIG. 2 is an enlarged schematic view of portion A of FIG. 1;
FIG. 3 is an enlarged schematic view of portion B of FIG. 1;
in the figure, 1, a frame body; 11. a piercing end; 12. an operation table; 13. a touch screen; 14. a start button; 15. an emergency stop button; 16. a solvent rack; 17. a lifting hook; 18. a needle head placing rack; 19. a clamping hole; 191. a pull-out groove; 2. an oscillation module; 21. loading a disc; 22. a placing rack; 23. placing the hole; 3. a public solvent injection module; 31. a first peristaltic pump; 32. a first needle unit; 33. a second needle unit; 35. a common solvent; 4. independent solvent split charging module; 41. a solvent rotating frame; 42. a clamping part; 43. a second peristaltic pump; 44. a third needle unit; 45. a fourth needle unit; 5. a needle moving unit; 51. an extension arm; 52. a positioning groove; 6. a mechanical action module; 61. clamping jaw.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings.
The present embodiment is only for explanation of the present invention and is not to be construed as limiting the present invention, and modifications to the present embodiment, which may not creatively contribute to the present invention as required by those skilled in the art after reading the present specification, are all protected by patent laws within the scope of claims of the present invention.
Examples:
as shown in fig. 1 to 3, a dispensing system for preparing insoluble medicines comprises a frame body 1, wherein the frame body 1 is used for being fixed or placed in a table top or a purifying box in a clean environment, the system comprises four parts of an oscillation module 2, a public solvent injection module 3, an independent solvent split charging module 4 and a mechanical action module 6, meanwhile, in order to reasonably utilize the idle time of an oscillation penicillin bottle, the three modules of the oscillation module 2, the public solvent injection module 3 and the independent solvent split charging module 4 of the system can be provided with a plurality of groups, in the embodiment, the two groups are arranged, the public solvent injection module 3 is used for injecting liquid in the public solvent 35 into the penicillin bottle in the oscillation module 2, the independent solvent split charging module 4 is used for injecting medicines in the oscillated penicillin bottle into independently packaged solvent bags, and meanwhile, the system is internally provided with a plurality of penicillin bottles and a plurality of solvent bags, and the independent dispensing of the solvent bags is completed.
As shown in fig. 1, the oscillation module 2 is disposed on the frame body 1, the oscillation module 2 includes a loading tray 21, a placement frame 22 and an oscillation unit, the placement frame 22 is disposed on the loading tray 21, a placement hole 23 for a penicillin bottle to be disposed is disposed on the placement frame 22, the aperture of the placement hole 23 is matched with the sidewall of the penicillin bottle, the placement frame 22 with different sizes can be replaced according to the sizes of different penicillin bottles, the oscillation unit adopts a structure such as a vibration motor, the vibration motor is connected with the bottom of the loading tray 21 through a bolt and the like, the connection between the oscillation unit and the loading tray 21 is realized, and the oscillation unit belongs to the prior art in the dispensing field and is not repeated herein.
As shown in fig. 1 and fig. 3, the common solvent injection module 3 includes a first peristaltic pump 31, a first needle unit 32, a second needle unit 33 and a common solvent 35, where the first needle unit 32, the second needle unit 33, the third needle unit 44 and the fourth needle unit 45 are identical in structure, i.e. one end of the needle unit has a piercing end 11, the other end is a connecting end for connecting with a hose for transfusion, the piercing end 11 of the first needle unit 32 is inserted into a top pocket of the common solvent 35 to realize communication, the communicating end of the first needle unit 32 is communicated with the communicating end of the second needle unit 33, in which a first hose is arranged between the first needle unit 32 and the second needle unit 33, and the first needle unit 32 and the second needle unit 33 are communicated through the first hose; as shown in fig. 3, the second needle unit 33 is movably connected to the frame 1, that is, the second needle unit can be removed from the frame 1 by the clamping jaw 61, a specific movable connection manner of the second needle unit and the frame 1 is disclosed below, the first peristaltic pump 31 is connected between the first needle unit 32 and the second needle unit 33, the first hose passes through the first peristaltic pump 31, and the liquid above the first needle unit 32 is injected from the second needle unit 33 through the first hose by the first peristaltic pump 31.
As shown in fig. 1 to 3, the independent solvent split charging module 4 comprises a solvent rotating frame 41, a second peristaltic pump 43, a third needle unit 44, a fourth needle unit 45 and a needle moving unit 5, wherein a clamping part 42 for clamping a solvent bag opening is arranged on the solvent rotating frame 41, the clamping part 42 is used for embedding the solvent bag opening into the clamping part 42 from the horizontal direction, the clamping part 42 is uniformly distributed in the circumferential direction of the solvent rotating frame 41, a motor is arranged at the bottom of the solvent rotating frame 41, a gear is arranged at the bottom of the solvent rotating frame 41, the motor drives the gear to rotate, the solvent rotating frame 41 is driven to rotate, the position movement of the clamping part 42 is realized, the solvent rotating frame 41 drives each solvent bag opening to move into a position corresponding to a puncture end 11 of the fourth needle unit 45, the puncture end 11 of the third needle unit 44 is connected to the frame body 1, the communication end of the third needle unit 44 is communicated with the communication end of the fourth needle unit 45 through a hose, the second peristaltic pump 43 is arranged between the third needle unit 44 and the fourth unit 45, namely, the third peristaltic pump 43 and the fourth needle unit 45 are arranged between the third needle unit 44 and the fourth needle unit 45, and the second peristaltic pump 45 is arranged towards the puncture end of the fourth needle unit 45 through the second hose.
As shown in fig. 1 and 2, the fourth needle unit 45 is disposed on the needle moving unit 5, the needle moving unit 5 drives the fourth needle unit 45 to move away from or puncture the solvent bag mouth, wherein the needle moving unit 5 includes a lifting cylinder, a extending arm 51 and a positioning groove 52, the lifting cylinder is disposed at the center of the solvent rotating frame 41, the movable end of the lifting cylinder is connected with the extending arm 51, the extending arm 51 extends to the above of the solvent bag mouth along the horizontal direction, the positioning groove 52 is disposed at one end of the extending arm 51, the fourth needle unit 45 is vertically connected in the positioning groove 52, and the puncturing end 11 of the fourth needle unit 45 is vertically disposed downward.
As shown in fig. 1, the mechanical action module 6 is a six-axis mechanical arm, a clamping jaw 61 is arranged on the six-axis mechanical arm, a finger cylinder is connected to an action end of the six-axis mechanical arm, the finger cylinder is connected with the clamping jaw 61, the mechanical action module 6 drives the clamping jaw 61 to clamp the second needle unit 33 to move and puncture the vial mouth, and the mechanical action module 6 drives the clamping jaw 61 to clamp the vial to move and puncture the puncture end 11 of the third needle unit 44.
As shown in fig. 1, in order to improve the dispensing efficiency, at least two groups of oscillation modules 2, common solvent injection modules 3 and independent solvent split charging modules 4 are arranged on a rack by using the idle time of oscillation, and in this embodiment, the oscillation modules 2, the common solvent injection modules 3 and the independent solvent split charging modules 4 are arranged in mirror images with a mechanical action module 6 as a center.
As shown in fig. 1, the front end of the frame body 1 is provided with an operation panel 12, one surface of the operation panel 12 facing outwards is provided with a touch screen 13, a start button 14 and an emergency stop button 15, a first peristaltic pump 31, a second peristaltic pump 43, a needle placement frame 18 and a solvent placement frame 16 are all arranged at the top of the operation panel 12, the solvent placement frame 16 is arranged in the middle of the top of the operation panel 12, the first peristaltic pump 31 is arranged between the needle placement frame 18 and the solvent placement frame 16, and the needle placement frame 18 is arranged between the second peristaltic pump 43 and the first peristaltic pump 31.
In order to hang two bags of public solvent 35 at the same time, the solvent placing frame 16 is arranged at the top of the operating platform 12, a hanging hole is arranged at the bottom of the public solvent 35, the solvent placing frame 16 is in a structure that a hanging hook 17 matched with the hanging hole is arranged on the solvent placing frame 16, the public solvent 35 is inversely arranged on the solvent placing frame 16, and the hanging hooks 17 are symmetrically arranged on the solvent placing frame 16.
As shown in fig. 3, in order to facilitate the gripping jaw 61 to take and place the needle unit, the needle holder 18 is disposed at the top of the console 12, and is specifically configured such that the second needle unit 33 and the third needle unit 44 are disposed on two sides of the needle holder 18, the needle holder 18 is provided with a clamping hole 19 for limiting the movement of the second needle unit 33 and the third needle unit 44 in the height direction, the clamping hole 19 extends outwards to form a release slot 191 for the second needle unit 33 and the third needle unit 44 to enter and leave the clamping hole 19, the puncture end 11 of the second needle unit 33 is disposed downward on the needle holder 18, and the puncture end 11 of the third annual unit is disposed upward on the needle holder 18.
A method of configuring a dispensing system for poorly soluble drugs, comprising the steps of,
step one, uniformly placing penicillin bottles on a vibration loading disc 21, reversely hanging a common solvent 35, and uniformly placing solvent bags on a solvent rotating frame 41;
step two, clamping the needle, connecting the first needle unit 32 with the second needle unit 33, connecting the third needle unit 44 with the fourth needle unit 45, and connecting the first needle unit 32 with the public solvent 35;
step three, the mechanical arm takes down the second needle head through the clamping jaw 61 and punctures the penicillin bottle, and the peristaltic pump works to inject the public solvent 35 into the penicillin bottle;
step four, after the liquid injection is finished, the vibration loading disc 21 works, the mechanical arm returns the needle through the clamping jaw 61, and the mechanical arm can carry out the procedures from step two to step four on other stations in the work of the vibration loading disc 21;
fifthly, after the vibration is finished, the mechanical arm inversely moves the penicillin bottle above the puncture end 11 of the third needle unit 44, the penicillin bottle is lowered to enable the third needle unit 44 to puncture the penicillin bottle, meanwhile, the fourth needle unit 45 is lowered to puncture the opening of the solvent bag, and the peristaltic pump works to inject liquid in the penicillin bottle into the solvent bag;
step six, after the conveying is finished, the mechanical arm returns the penicillin bottles, and the steps three to six are repeated until the conveying of the liquid medicine with the number of penicillin bottles required by the single-bag solvent bag is finished;
step seven, lifting the fourth needle unit 45, rotating the solvent rotating frame 41, rotating the next bag of solvent bag to the lower part of the fourth needle unit 45, and continuing dispensing until the configuration of the penicillin bottle or the solvent bag is completed.
Working principle:
placing a plurality of penicillin bottles in sequence in the placing holes 23 of the placing frame 22, inversely hanging two bags of common solvent 35 on the solvent placing frame 16, and simultaneously clamping the plurality of solvent bags in sequence on the clamping part 42 of the solvent rotating frame 41;
connecting the first needle unit 32 with the second needle unit 33 through a first hose, connecting the third needle unit 44 with the fourth needle unit 45 through a second hose, and inserting the piercing end 11 of the first needle unit 32 into the mouth of the common solvent 35; the equipment is started through the starting button 14 on the operating platform 12, the six-axis mechanical arm takes down the second needle through the clamping jaw 61 and moves towards the placement frame 22, when the equipment moves to the position above the penicillin bottle, the second needle pierces the penicillin bottle by downward movement, and the first peristaltic pump 31 works to inject the common solvent 35 into the penicillin bottle; after one penicillin bottle can be filled with liquid or a plurality of penicillin bottles can be filled, the oscillating unit acts to drive the loading disc 21 to oscillate; in the process, liquid preparation at another station can be carried out; after the oscillation is finished, the mechanical arm clamps the penicillin bottle through the clamping jaw 61 and reversely moves above the puncture end 11 of the third needle unit 44, the penicillin bottle is lowered to enable the puncture end 11 of the third needle unit 44 to puncture the penicillin bottle, and simultaneously, or before or after the penicillin bottle is vibrated, the fourth needle unit 45 is lowered to puncture the solvent bag mouth, and the peristaltic pump works to inject liquid in the penicillin bottle into the solvent bag; after the conveying is finished, the mechanical arm returns the penicillin bottles into the placement frame 22, and the steps three to six are repeated until the conveying of the liquid medicine with the number of penicillin bottles required by the single-bag solvent bag is finished; the lifting cylinder lifts the fourth needle unit 45, the motor rotates the solvent rotating frame 41, and the next bag of solvent bag is rotated to the lower part of the fourth needle unit 45, and the medicine dispensing is continued until all the penicillin bottles or all the solvent bags are arranged.
Claims (10)
1. A dispensing system for dispensing poorly soluble drugs, comprising a frame (1), characterized in that: the shake module (2) is arranged on the frame body (1), the shake module (2) comprises a loading disc (21), a placing frame (22) and a shake unit, the placing frame (22) is arranged on the loading disc (21), a placing hole (23) for arranging a penicillin bottle is formed in the placing frame (22), and the shake unit is connected with the loading disc (21);
the common solvent injection module (3), the common solvent injection module (3) comprises a first peristaltic pump (31), a first needle unit (32), a second needle unit (33) and a common solvent (35), a puncture end (11) of the first needle unit (32) is communicated with the common solvent (35), a communication end of the first needle unit (32) is communicated with a communication end of the second needle unit (33), the second needle unit (33) is movably connected to the frame body (1), and the first peristaltic pump (31) is connected between the first needle unit (32) and the second needle unit (33);
the independent solvent split charging module (4), independent solvent split charging module (4) comprises a solvent rotary frame (41), a second peristaltic pump (43), a third needle unit (44), a fourth needle unit (45) and a needle moving unit (5), wherein a clamping part (42) for clamping a solvent bag opening is arranged on the solvent rotary frame (41), a puncture end (11) of the third needle unit (44) is connected to the frame body (1), the communication end of the third needle unit (44) is communicated with the communication end of the fourth needle unit (45), the fourth needle unit (45) is arranged on the needle moving unit (5), the second peristaltic pump (43) is arranged between the third needle unit (44) and the fourth needle unit (45), a puncture end (11) of the fourth needle unit (45) is arranged towards a solvent bag opening, the moving unit (5) drives the fourth needle unit (45) to move away from or puncture the solvent bag opening, and the solvent rotary frame (41) drives each needle bag opening to move into the corresponding position (11) of the fourth needle unit (45);
the mechanical action module (6), the mechanical action module (6) includes clamping jaw (61), mechanical action module (6) drive clamping jaw (61) centre gripping second syringe needle unit (33) remove and puncture xiLin bottle bottleneck, mechanical action module (6) drive clamping jaw (61) clamping xiLin bottle remove and puncture piercing end (11) of third syringe needle unit (44).
2. A dispensing system for dispensing poorly soluble drugs as defined in claim 1, wherein: the vibration module (2), the public solvent injection module (3) and the independent solvent split charging module (4) are arranged in the rack, and the vibration module (2), the public solvent injection module (3) and the independent solvent split charging module (4) are arranged in a mirror image mode by taking the mechanical action module (6) as a center.
3. A dispensing system for poorly soluble drugs according to claim 2, wherein: the solvent rack is characterized in that a solvent rack (16) is arranged on the rack body (1), hanging holes are formed in the bottoms of the public solvents (35), lifting hooks (17) matched with the hanging holes are arranged on the solvent rack (16), the public solvents (35) are inversely arranged on the solvent rack (16), and the lifting hooks (17) are symmetrically arranged on the solvent rack (16).
4. A dispensing system for poorly soluble drugs according to claim 3, characterized in that: be provided with syringe needle rack (18) on support body (1), second syringe needle unit (33) and third syringe needle unit (44) set up in the both sides of syringe needle rack (18), be provided with joint hole (19) that restriction second syringe needle unit (33) and third syringe needle unit (44) removed in the direction of height on syringe needle rack (18), joint hole (19) outwards extend and form and supply second syringe needle unit (33) and third syringe needle unit (44) to get into and leave escape groove (191) of joint hole (19), puncture end (11) of second syringe needle unit (33) set up down on syringe needle rack (18), puncture end (11) of third this year's head unit sets up on syringe needle rack (18).
5. A dispensing system for poorly soluble drugs according to claim 4, wherein: be provided with operation panel (12) on support body (1), one side outwards of operation panel (12) is provided with touch-sensitive screen (13), start button (14) and scram button (15), first peristaltic pump (31), second peristaltic pump (43), syringe needle rack (18) and solvent rack (16) all set up at operation panel (12) top, solvent rack (16) set up in the centre at operation panel (12) top, first peristaltic pump (31) set up between syringe needle rack (18) and solvent rack (16), syringe needle rack (18) set up between second peristaltic pump (43) and first peristaltic pump (31).
6. A dispensing system for poorly soluble drugs according to claim 5, wherein: a first hose is arranged between the first needle unit (32) and the second needle unit (33), a second hose is arranged between the third needle unit (44) and the fourth needle unit (45), the first hose passes through the first peristaltic pump (31), and the second hose passes through the second peristaltic pump (43).
7. A dispensing system for poorly soluble drugs according to claim 6, wherein: the mechanical action module (6) is a six-axis mechanical arm, the action end of the six-axis mechanical arm is connected with a finger cylinder, and the finger cylinder is connected with the clamping jaw (61).
8. A dispensing system for dispensing poorly soluble drugs as defined in claim 1, wherein: the needle moving unit (5) comprises a lifting cylinder, an extension arm (51) and a positioning groove (52), wherein the lifting cylinder is arranged at the center of the solvent rotating frame (41), the movable end of the lifting cylinder is connected with the extension arm (51), the extension arm (51) extends to the upper portion of a solvent bag mouth along the horizontal direction, the positioning groove (52) is arranged at one end of the lifting cylinder based on the principle of the extension arm (51), the fourth needle unit (45) is vertically connected in the positioning groove (52), and the puncturing end (11) of the fourth needle unit (45) is vertically downwards arranged.
9. A dispensing method for preparing poorly soluble drugs, characterized by: comprises the steps of,
step one, uniformly placing penicillin bottles on an oscillation loading disc (21), reversely hanging a public solvent (35), and uniformly placing solvent bags on a solvent rotating frame (41);
step two, clamping the needle, connecting a first needle unit (32) with a second needle unit (33), connecting a third needle unit (44) with a fourth needle unit (45), and connecting the first needle unit (32) with a public solvent (35);
step three, the mechanical arm takes down the second needle head through the clamping jaw (61) and punctures the penicillin bottle, and the peristaltic pump works to inject the common solvent (35) into the penicillin bottle;
step four, after the liquid injection is finished, oscillating the loading disc (21) to work, and the mechanical arm puts back the needle through the clamping jaw (61);
fifthly, after the vibration is finished, the mechanical arm inversely moves the penicillin bottle above a puncture end (11) of a third needle unit (44), the penicillin bottle is lowered to enable the third needle unit (44) to puncture the penicillin bottle, meanwhile, a fourth needle unit (45) is lowered to puncture a solvent bag mouth, and a peristaltic pump works to inject liquid in the penicillin bottle into the solvent bag;
step six, after the conveying is finished, the mechanical arm returns the penicillin bottles, and the steps three to six are repeated until the conveying of the liquid medicine with the number of penicillin bottles required by the single-bag solvent bag is finished;
and step seven, lifting the fourth needle head unit (45), rotating the solvent rotating frame (41), rotating the next bag of solvent bag to the position below the fourth needle head unit (45), and continuing dispensing until the configuration of the penicillin bottle or the solvent bag is completed.
10. A method of dispensing poorly soluble drugs according to claim 9, wherein: in the fourth step, the mechanical arm can perform the procedures from the second step to the fourth step on other stations in the work of oscillating the loading disc (21).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311209711.5A CN117100601A (en) | 2023-09-19 | 2023-09-19 | Dispensing system and method for preparing indissolvable drugs |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311209711.5A CN117100601A (en) | 2023-09-19 | 2023-09-19 | Dispensing system and method for preparing indissolvable drugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN117100601A true CN117100601A (en) | 2023-11-24 |
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ID=88794790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202311209711.5A Pending CN117100601A (en) | 2023-09-19 | 2023-09-19 | Dispensing system and method for preparing indissolvable drugs |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN117100601A (en) |
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2023
- 2023-09-19 CN CN202311209711.5A patent/CN117100601A/en active Pending
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