CN117042794A - 用于免疫疗法的t细胞免疫球蛋白和粘蛋白结构域3(tim3)组合物和方法 - Google Patents

用于免疫疗法的t细胞免疫球蛋白和粘蛋白结构域3(tim3)组合物和方法 Download PDF

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Publication number
CN117042794A
CN117042794A CN202280022874.XA CN202280022874A CN117042794A CN 117042794 A CN117042794 A CN 117042794A CN 202280022874 A CN202280022874 A CN 202280022874A CN 117042794 A CN117042794 A CN 117042794A
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tim3
chr5
chr16
sequence
chr12
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Chinese (zh)
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D·R·库克
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Intellia Therapeutics Inc
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Intellia Therapeutics Inc
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    • C12N15/90—Stable introduction of foreign DNA into chromosome
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    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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    • C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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    • C12N2510/00—Genetically modified cells

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  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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CN202280022874.XA 2021-02-08 2022-02-07 用于免疫疗法的t细胞免疫球蛋白和粘蛋白结构域3(tim3)组合物和方法 Pending CN117042794A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163147221P 2021-02-08 2021-02-08
US63/147,221 2021-02-08
PCT/US2022/015496 WO2022170193A2 (en) 2021-02-08 2022-02-07 T-cell immunoglobulin and mucin domain 3 (tim3) compositions and methods for immunotherapy

Publications (1)

Publication Number Publication Date
CN117042794A true CN117042794A (zh) 2023-11-10

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CN202280022874.XA Pending CN117042794A (zh) 2021-02-08 2022-02-07 用于免疫疗法的t细胞免疫球蛋白和粘蛋白结构域3(tim3)组合物和方法

Country Status (5)

Country Link
US (1) US20230374456A1 (https=)
EP (1) EP4288089A2 (https=)
JP (1) JP2024506016A (https=)
CN (1) CN117042794A (https=)
WO (1) WO2022170193A2 (https=)

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WO2025128871A2 (en) 2023-12-13 2025-06-19 Renagade Therapeutics Management Inc. Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents
WO2026006390A2 (en) * 2024-06-26 2026-01-02 Intellia Therapeutics, Inc. Modified guide rnas for genome editing

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JPH10500310A (ja) 1994-05-19 1998-01-13 ダコ アクティーゼルスカブ 淋菌及びトラコーマ クラミジアの検出のためのｐｎａ プローブ
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WO2022170193A2 (en) 2022-08-11
WO2022170193A3 (en) 2022-11-24
JP2024506016A (ja) 2024-02-08
US20230374456A1 (en) 2023-11-23
EP4288089A2 (en) 2023-12-13

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