CN116983369A - A topical pharmaceutical composition for treating traumatic hemorrhage, and its preparation method - Google Patents

A topical pharmaceutical composition for treating traumatic hemorrhage, and its preparation method Download PDF

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CN116983369A
CN116983369A CN202311127461.0A CN202311127461A CN116983369A CN 116983369 A CN116983369 A CN 116983369A CN 202311127461 A CN202311127461 A CN 202311127461A CN 116983369 A CN116983369 A CN 116983369A
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pharmaceutical composition
herba
traumatic hemorrhage
treating traumatic
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张彬炜
张福
陈志辉
王志刚
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Abstract

A pharmaceutical composition for external use for treating traumatic hemorrhage is a medicament prepared from the following pharmaceutical raw materials in parts by weight: 20-60 parts of cattail pollen, japanese thistle, herba Cephalanoploris and herba selaginellae; 30-70 parts of nutgall, hairyvein agrimony, madder and mica respectively; 40-80 parts of red halloysite, pulvis Fumi Carbonisatus, pseudo-ginseng and humifuse euphorbia herb respectively; 50-90 parts of carbonized hair, cogongrass rhizome, cuttlebone and dragon's blood respectively; in conclusion, the external pharmaceutical composition disclosed by the invention contains a plurality of trace elements such as flavonoids, m-benzene triphenols, monoterpenes, dandelion sterol acetate, organic acid, quercetin, tannins, silicate minerals and the like, has the effects of stopping bleeding, detumescence, sterilization, promoting granulation and relieving pain, can well treat traumatic hemorrhage, and has a synergistic effect after various medicinal materials are combined according to the formula proportion, the curative effect can be obviously improved, and the scientific proportioning is carried out on the dosage, so that the composition disclosed by the invention can play a role in treatment without worrying about side effects caused by the medicinal materials.

Description

A topical pharmaceutical composition for treating traumatic hemorrhage, and its preparation method
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to an external pharmaceutical composition for treating traumatic hemorrhage and a preparation method thereof.
Background
Traumatic bleeding refers to external bleeding, which is usually caused by knife cuts, stabs, gun shots, rolling wounds, and the like, and is usually treated in hospitals, and the hemostatic method is different according to the type of bleeding. In the existing medicines for treating traumatic hemorrhage, the traditional Chinese medicines and the western medicines are used, but the defects of unobvious effect, slow wound healing, side effects caused by medicines and the like are common.
Disclosure of Invention
The invention aims to provide an external pharmaceutical composition for treating traumatic hemorrhage and a preparation method thereof, and solves the technical problems that the existing traditional Chinese medicine and western medicine are applied to treating traumatic hemorrhage, the wound healing is slow, and side effects are easy to cause.
In order to solve the technical problems, the invention adopts the following technical scheme:
a pharmaceutical composition for external use for treating traumatic hemorrhage is a medicament prepared from the following pharmaceutical raw materials in parts by weight:
20-60 parts of cattail pollen, japanese thistle, herba Cephalanoploris and herba selaginellae; 30-70 parts of nutgall, hairyvein agrimony, madder and mica respectively; 40-80 parts of red halloysite, pulvis Fumi Carbonisatus, pseudo-ginseng and humifuse euphorbia herb respectively; 50-90 parts of carbonized hair, cogongrass rhizome, cuttlebone and dragon's blood respectively.
Further, an external pharmaceutical composition for treating traumatic hemorrhage comprises the following raw materials in parts by weight:
30-50 parts of cattail pollen, japanese thistle, herba Cephalanoploris and herba selaginellae; 40-60 parts of nutgall, hairyvein agrimony, madder and mica respectively; 50-70 parts of red halloysite, pulvis Fumi Carbonisatus, pseudo-ginseng and humifuse euphorbia herb respectively; 60-80 parts of carbonized hair, cogongrass rhizome, cuttlebone and dragon's blood respectively.
Furthermore, the external pharmaceutical composition for treating traumatic hemorrhage has the same weight ratio of pollen typhae, herba seu radix Cirsii Japonici, herba Cephalanoploris and herba Selaginellae, the same weight ratio of Galla chinensis, herba et Gemma Agrimoniae, radix Rubiae and Muscovitum, the same weight ratio of Halloysitum rubrum, pulvis Fumi Carbonisatus, notoginseng radix and herba Euphorbiae Humifusae, and the same weight ratio of crinis Carbonisatus, lalang grass rhizome, os Sepiae and sanguis Draxonis.
Further, an external pharmaceutical composition for treating traumatic hemorrhage comprises the following raw materials in parts by weight: 40 parts of cattail pollen, japanese thistle, herba Cephalanoploris and herba selaginellae; 50 parts of nutgall, hairyvein agrimony, madder and mica respectively; 60 parts of red halloysite, pulvis Fumi Carbonisatus, pseudo-ginseng and humifuse euphorbia herb respectively; each of the carbonized hair, the cogongrass rhizome, the cuttlebone and the dragon's blood is 70 parts.
Further, a pharmaceutical composition for external use for treating traumatic hemorrhage is in the form of powder, tablet, paste, tincture, pill or syrup.
A method for preparing an external pharmaceutical composition for treating traumatic hemorrhage, comprising the steps of: the preparation method comprises the steps of mixing the raw materials according to weight ratio, processing, drying, grinding to obtain powder, and preparing into topical pharmaceutical composition.
The external pharmaceutical composition is prepared according to the traditional Chinese medicine theory, and the dosage is scientifically proportioned, so that the composition can play a role in treatment without worrying about side effects caused by medicines, and meanwhile, the results of modern pharmacological research and clinical research show that the composition has definite curative effect and no side effects, and the chemical components of the selected pharmaceutical raw materials are as follows:
pollen Typhae: mainly comprises naringenin, typha saponin, steroid, polysaccharide and other components, has the effects of astringing to stop bleeding, activating blood and removing blood stasis;
radix seu herba Cirsii Japonici: mainly comprises components such as the salangid, the dandelion sterol acetate, the caryophyllene and the like, and has the effects of cooling blood, stopping bleeding, removing stasis and relieving swelling;
herba Cephalanoploris: mainly comprises rutin, linarin, protocatechuic acid, chlorogenic acid, caffeic acid, taraxacum sterol acetate and other components, and has the effects of cooling blood, stopping bleeding, removing blood stasis, detoxifying and eliminating carbuncles;
gallnut: mainly comprises tannins, gallic acid, fatty acid and other components, and has the effects of astringing lung to reduce fire, astringing intestines to check diarrhea, arresting sweating, stopping bleeding, and astringing dampness to arrest sore;
herba et Gemma Agrimoniae: mainly comprises flavonoid, phloroglucinol, agrimony lactone, tannins and other components, and has the effects of astringing to stop bleeding, checking malaria, stopping diarrhea, detoxifying and tonifying deficiency;
radix Rubiae: mainly comprises madder acid, alizarin, terpenes, polysaccharide, cyclopeptide compound and other components, and has the effects of cooling blood, removing blood stasis, stopping bleeding and dredging channels;
halloysitum rubrum: mainly comprises silicon aluminum tetrahydrate, ferric oxide and other components, has the effects of astringing intestines, stopping bleeding, promoting tissue regeneration and healing sore;
grass cream: has the effects of stopping bleeding, removing food retention, removing toxic substances, and clearing pathogenic fire;
residual carbon in blood: has effects in promoting granulation, healing wound, eliminating dampness, relieving swelling, and promoting wound healing;
herba Selaginellae: has effects of sexual pungent, antiinflammatory, hemostatic and repercussive;
lalang grass rhizome: mainly comprises imperatorin, arundoin, imperatorin, organic acid, sterol, saccharide and other components, and has the effects of cooling blood, stopping bleeding, clearing heat, promoting the production of body fluid, promoting urination and treating stranguria;
herba Euphorbiae Humifusae: mainly comprises flavonoid, coumarin, organic acid and other components, and has the effects of clearing heat and detoxicating, cooling blood and stopping bleeding, promoting diuresis and removing jaundice;
dragon's blood: mainly comprises the components of resina Draconis, flavanol, chalcone, abietic acid, mountain-answering pinoic acid and the like, and has the effects of activating blood circulation, relieving pain, removing blood stasis, stopping bleeding, promoting granulation and healing sore;
cuttlebone: mainly comprises calcium carbonate, sodium chloride, calcium phosphate and other components, and has the effects of astringing, stopping bleeding, astringing essence, stopping leukorrhagia, relieving hyperacidity, relieving pain, astringing dampness and promoting wound healing;
mica: mainly comprises silicate minerals, sodium, magnesium, lithium, iron and other trace elements, and can treat traumatic hemorrhage;
pseudo-ginseng: mainly comprises ginsenoside, notoginsenoside, esculin, tetracyclic triterpenes and other components, and has the effects of removing blood stasis, stopping bleeding, detumescence and relieving pain.
Compared with the prior art, the invention has the beneficial effects that: the external pharmaceutical composition disclosed by the invention contains a plurality of trace elements such as flavonoids, m-benzene triphenols, monoterpenes, dandelion sterol acetate, organic acids, quercetin, tannins, silicate minerals and the like, has the effects of stopping bleeding, detumescence, sterilization, promoting granulation and relieving pain, can well treat traumatic hemorrhage, has a synergistic effect after various medicinal materials are combined according to the formula proportion, can obviously improve the curative effect, and can be scientifically proportioned in dosage, so that the composition disclosed by the invention can play a role in treatment without worrying about side effects caused by the medicinal materials.
Detailed Description
The following description of the technical solutions in the embodiments of the present invention will be clear and complete, and it is obvious that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
The present invention is described in further detail below with reference to examples.
Example 1: an external pharmaceutical composition for treating traumatic hemorrhage comprises the following raw materials in parts by weight: 35 parts of cattail pollen, japanese thistle, herba Cephalanoploris and herba selaginellae; 50 parts of nutgall, hairyvein agrimony, madder and mica respectively; 55 parts of red halloysite, pulvis Fumi Carbonisatus, pseudo-ginseng and humifuse euphorbia herb respectively; 66 parts of carbonized hair, cogongrass rhizome, cuttlebone and dragon's blood respectively;
the preparation method comprises the steps of mixing the above raw materials according to weight ratio, processing, drying, grinding to obtain powder, and making into topical pharmaceutical composition.
Example 2: an external pharmaceutical composition for treating traumatic hemorrhage comprises the following raw materials in parts by weight: 40 parts of cattail pollen, japanese thistle, herba Cephalanoploris and herba selaginellae; 50 parts of nutgall, hairyvein agrimony, madder and mica respectively; 60 parts of red halloysite, pulvis Fumi Carbonisatus, pseudo-ginseng and humifuse euphorbia herb respectively; 70 parts of carbonized hair, cogongrass rhizome, cuttlebone and dragon's blood respectively;
the preparation method comprises the steps of mixing the above raw materials according to weight ratio, processing, drying, grinding to obtain powder, and making into topical pharmaceutical composition.
Example 3: an external pharmaceutical composition for treating traumatic hemorrhage comprises the following raw materials in parts by weight: 60 parts of cattail pollen, japanese thistle, herba Cephalanoploris and selaginella tamariscina respectively; 70 parts of nutgall, hairyvein agrimony, madder and mica respectively; 80 parts of red halloysite, pulvis Fumi Carbonisatus, pseudo-ginseng and humifuse euphorbia herb respectively; the raw materials comprise 90 parts of carbonized hair, cogongrass rhizome, cuttlebone and dragon's blood.
In order to better verify the curative effect of the external-use pharmaceutical composition of the invention, the beneficial effects of the external-use pharmaceutical composition of the invention on traumatic hemorrhage are illustrated by the following clinical observation data.
Case 1: long Mou women, 8 years old, have more blood flow and severe pain due to careless impact of stones on the forehead; the wound is cleaned and disinfected after being pressed for a while, the traditional Chinese medicine is externally applied to an affected part and is wrapped, and then blood flow is stopped immediately, so that pain is relieved; after 5 days the wound healed completely and was scarred.
Case 2: hu Mou when a man, 60 years old, walks carelessly and slips down in rainy days, so that the right arm and the belt meat are scratched off by stones, the wound is about 5cm long and about 3cm wide, the blood flow is more than, the pain is severe, after the bleeding of the wound is relieved by pressing, the wound is immediately cleaned and disinfected, the traditional Chinese medicine is externally applied and wrapped, the blood flow is reduced, and the blood flow is stopped after about 5 minutes, so that the pain is relieved; the wound heals after 4 days, and the wound is scarred after 5 days, and the scar is small.
Case 3: zhao Mou when a man is 50 years old, the sole of the man is carelessly pricked by nails during sundries collection, the blood flow is not only stable, but the man is painful and can not walk when the nails are pulled out; the wound is cleaned immediately, and then the traditional Chinese medicine is applied to the affected part and wrapped, so that the blood flow is reduced, and the pain is relieved; after 5 days, the wound heals well, but the finger is pressed on the affected part to feel slight pain, the wound is scarred after 3 days, the affected part has no pain, and the walking is free.
Case 4: zhang Mou when a man is 30 years old, the man cuts the food from 1/4 of the 1 st joint of the left index finger carelessly during cutting, so that the blood flow is not only severe, the pain is severe, the cut finger is reset and fixed immediately, and the traditional Chinese medicine is wrapped, so that the blood flow is slowly reduced, and the pain is relieved; after 10 days, the fingers are well combined, the broken fingers can slightly bounce, and after 3 days, the wound heals the scar, and the fingers can freely move.
It should be noted that in this document, terms such as "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus.
Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made therein without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (6)

1. The external medicine composition for treating traumatic hemorrhage is characterized by being prepared from the following medicine raw materials in parts by weight:
20-60 parts of cattail pollen, japanese thistle, herba Cephalanoploris and herba selaginellae; 30-70 parts of nutgall, hairyvein agrimony, madder and mica respectively; 40-80 parts of red halloysite, pulvis Fumi Carbonisatus, pseudo-ginseng and humifuse euphorbia herb respectively; 50-90 parts of carbonized hair, cogongrass rhizome, cuttlebone and dragon's blood respectively.
2. The external pharmaceutical composition for treating traumatic hemorrhage according to claim 1, wherein the weight ratio of the raw materials of the medicine is:
30-50 parts of cattail pollen, japanese thistle, herba Cephalanoploris and herba selaginellae; 40-60 parts of nutgall, hairyvein agrimony, madder and mica respectively; 50-70 parts of red halloysite, pulvis Fumi Carbonisatus, pseudo-ginseng and humifuse euphorbia herb respectively; 60-80 parts of carbonized hair, cogongrass rhizome, cuttlebone and dragon's blood respectively.
3. The external pharmaceutical composition for treating traumatic hemorrhage according to claim 1, wherein the weight ratio of pollen typhae, herba seu radix Cirsii Japonici, herba Cephalanoploris and herba Selaginellae is the same, the weight ratio of Galla chinensis, herba et Gemma Agrimoniae, radix Rubiae and Muscovitum is the same, halloysitum rubrum, pulvis Fumi Carbonisatus, notoginseng radix and herba Euphorbiae Humifusae is the same, and crinis Carbonisatus, lalang grass rhizome, os Sepiae and sanguis Draxonis are the same.
4. The external pharmaceutical composition for treating traumatic hemorrhage according to claim 3, wherein the weight ratio of the raw materials of the drugs is: 40 parts of cattail pollen, japanese thistle, herba Cephalanoploris and herba selaginellae; 50 parts of nutgall, hairyvein agrimony, madder and mica respectively; 60 parts of red halloysite, pulvis Fumi Carbonisatus, pseudo-ginseng and humifuse euphorbia herb respectively; each of the carbonized hair, the cogongrass rhizome, the cuttlebone and the dragon's blood is 70 parts.
5. The pharmaceutical composition for external use for treating traumatic hemorrhage according to any one of claims 1 to 4, wherein the dosage form of the pharmaceutical composition for external use is a powder, a tablet, a paste, a tincture, a pill or a syrup.
6. A method of preparing a topical pharmaceutical composition for treating traumatic hemorrhage, comprising the steps of: the preparation method comprises the steps of mixing the raw materials according to weight ratio, processing, drying, grinding to obtain powder, and preparing into topical pharmaceutical composition.
CN202311127461.0A 2023-09-04 2023-09-04 A topical pharmaceutical composition for treating traumatic hemorrhage, and its preparation method Pending CN116983369A (en)

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