CN116880160A - Method and system for monitoring pill making process of medicine strips - Google Patents
Method and system for monitoring pill making process of medicine strips Download PDFInfo
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- CN116880160A CN116880160A CN202311140205.5A CN202311140205A CN116880160A CN 116880160 A CN116880160 A CN 116880160A CN 202311140205 A CN202311140205 A CN 202311140205A CN 116880160 A CN116880160 A CN 116880160A
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- 239000003814 drug Substances 0.000 title claims abstract description 176
- 238000000034 method Methods 0.000 title claims abstract description 62
- 239000006187 pill Substances 0.000 title claims abstract description 45
- 230000008569 process Effects 0.000 title claims abstract description 29
- 238000012544 monitoring process Methods 0.000 title claims abstract description 21
- 229940079593 drug Drugs 0.000 claims abstract description 27
- 238000001514 detection method Methods 0.000 claims description 49
- 230000009471 action Effects 0.000 claims description 9
- 230000008859 change Effects 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 4
- 230000000737 periodic effect Effects 0.000 claims description 4
- 238000004806 packaging method and process Methods 0.000 claims description 3
- 230000033228 biological regulation Effects 0.000 claims description 2
- 230000009699 differential effect Effects 0.000 claims description 2
- 239000002245 particle Substances 0.000 abstract description 2
- 239000000463 material Substances 0.000 description 10
- 238000001125 extrusion Methods 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 5
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- 238000010586 diagram Methods 0.000 description 3
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- 239000007962 solid dispersion Substances 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
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- 230000000694 effects Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000010094 polymer processing Methods 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 238000011158 quantitative evaluation Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B11/00—Automatic controllers
- G05B11/01—Automatic controllers electric
- G05B11/36—Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential
- G05B11/42—Automatic controllers electric with provision for obtaining particular characteristics, e.g. proportional, integral, differential for obtaining a characteristic which is both proportional and time-dependent, e.g. P.I., P.I.D.
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2200/00—General characteristics or adaptations
- A61J2200/20—Extrusion means, e.g. for producing pharmaceutical forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2200/00—General characteristics or adaptations
- A61J2200/70—Device provided with specific sensor or indicating means
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P90/00—Enabling technologies with a potential contribution to greenhouse gas [GHG] emissions mitigation
- Y02P90/02—Total factory control, e.g. smart factories, flexible manufacturing systems [FMS] or integrated manufacturing systems [IMS]
Abstract
The application discloses a method and a system for monitoring a pill making process of a medicine strip, wherein the method comprises the following steps: obtaining a first value of a drug strip, wherein the first value comprises at least one of: the diameter, radius and circumference of the medicine strip; determining the deviation amount of the extruded medicine strip according to the first numerical value of the medicine strip and the preset second numerical value of the medicine strip; and controlling pharmaceutical equipment to adjust the first numerical value of the extruded medicine strip according to the deviation amount of the medicine strip. By the arrangement, the particle size of the prepared pill is basically consistent, and the quality of the pill is improved, so that the control of the patient on the dosage is ensured.
Description
Technical Field
The application relates to traditional Chinese medicine manufacturing equipment, in particular to a method and a system for monitoring a pill making process of a medicine strip.
Background
Extrusion molding technology is an important molding means and is widely applied to the field of polymer processing. At present, the extrusion molding technology is also highly concerned in the field of pharmaceutical preparations, and one application case is the preparation of solid dispersions such as honeyed pills, watered pills, micropills and the like. The solid dispersion provides an effective technical method for improving the problems of solubility, bioavailability and the like of the insoluble medicine, has a research application history of nearly 60 years, and has a large number of preparation varieties.
The extrusion pill making process comprises the steps of feeding, extruding medicine strips, cutting the medicine strips, rubbing pills and the like, and specifically comprises the following steps: adding the mixed or refined medicine materials into a feed port of a screw propeller of a pill making machine, rotating the screw propeller blades inwards, pressing the medicine materials into the rotating screw grooves, and extruding the medicine materials into cylindrical medicine strips; the medicine strips extruded from the strip outlet pass through the guide wheel and drop into the strip separator, and the medicine strips are continuously cut by the double rubbing wheels and rubbed into pills.
At present, no literature reports on online measurement, characterization and automatic regulation and control methods of the diameter of an extruded medicine strip in the extrusion and pelleting process in the field of pharmaceutical preparations, quantitative evaluation and automatic control of the state of the extrusion process are difficult in industrial production, and the diameter of the extruded medicine strip has a key influence on the subsequent process and the quality of a final product.
Disclosure of Invention
In order to solve the defects in the prior art, the application aims to provide a method and a system for monitoring the pill making process of a medicine strip, so that the consistency of the diameters of the prepared pills is higher, and the quality of the pills is improved.
In order to achieve the above purpose, the present application adopts the following technical scheme:
the application provides a method for monitoring a pill making process of a medicine strip, which comprises the following steps:
obtaining a first value of the drug strip, wherein the first value comprises at least one of the following: the diameter, radius and circumference of the medicine strip;
determining the deviation amount of the extruded medicine strip according to the first numerical value of the medicine strip and the second numerical value of the preset medicine strip;
and controlling the pharmaceutical equipment to adjust the first numerical value of the extruded medicine strip according to the deviation amount of the medicine strip.
Further, controlling the pharmaceutical device to adjust a first value of the extruded drug strip according to the deviation amount of the drug strip, comprising:
determining a control amount for adjusting the pharmaceutical equipment according to the deviation amount of the medicine strip;
and adjusting the pressure threshold of the pharmaceutical equipment according to the control quantity.
Further, adjusting a pressure threshold of the pharmaceutical equipment according to the control amount, comprising:
according to the preset adjusting interval, if the control quantity is in the preset adjusting interval, the first numerical value of the medicine strip is adjusted by controlling the screw rotating speed of the pharmaceutical equipment to adjust the pressure threshold.
Further, controlling the pharmaceutical device to adjust a first value of the extruded drug strip according to the deviation amount of the drug strip, comprising:
and according to a preset adjusting interval, if the control quantity is outside the adjusting interval, adjusting the pressure threshold value by controlling the feeding speed of the pharmaceutical equipment, so as to adjust the first numerical value of the medicine strip.
Further, determining a control amount for adjusting the pharmaceutical equipment according to the deviation amount of the medicine strip includes:
the control amount satisfies the following relation:
；
wherein ,for controlling quantity, ++>Is a proportional action coefficient, ++>For integral action coefficient, +.>For differentiating action coefficient, ++>For constant controller bias, +.>Is->The amount of deviation of the strip at the moment.
Further, the method further comprises:
and performing filtering operation on the first numerical value of the medicine strip to filter out periodic interference noise of the first numerical value of the medicine strip.
Further, the method further comprises:
packaging the first numerical value of the medicine strip into a detection signal, amplifying the detection signal, and transmitting the detection signal to a controller;
and displaying a numerical change curve of the medicine strip on a display interface of the controller according to the amplified detection signal.
The application also provides a system for monitoring the pill making process of the medicine strip, which comprises:
the pharmaceutical equipment comprises a strip outlet, and the medicine strips pressed and formed by the pharmaceutical equipment are extruded from the strip outlet;
the system further comprises:
the detection module is used for detecting the first numerical value of the medicine strip, and the detection module packages the first numerical value of the medicine strip into a detection signal;
the control module is connected with the detection module and used for acquiring detection signals, and a second numerical value of the medicine strip is preset in the control module; the control module determines a deviation amount of the medicine strip according to the first value and the second value of the medicine strip, determines a control amount for adjusting the pharmaceutical equipment according to the deviation amount of the medicine strip, and determines a pressure threshold of the pharmaceutical equipment according to the control amount.
Further, the detection module comprises at least one and any combination of the following: the laser transmitter and the laser receiver are respectively arranged at two sides of the medicine strip.
Further, the control module further includes:
the judging unit is used for judging whether the control quantity is in a preset adjusting interval or not, and if the control quantity is in the adjusting interval, the control module adjusts the first numerical value of the medicine strip by controlling the screw speed of the pharmaceutical equipment; and if the control quantity is outside the adjustment interval, the control module adjusts the first numerical value of the medicine strip by controlling the feeding speed of the pharmaceutical equipment.
The method and the system for monitoring the pill making process of the medicine strips are characterized in that the first numerical value of the medicine strips is detected, and the deviation amount of the medicine strips is determined according to the preset second numerical value, so that the control module can determine the adjustment threshold according to the deviation amount of the medicine strips.
Drawings
FIG. 1 is a flow chart of a method of monitoring a pill making process of a pill making process monitoring system according to an embodiment of the application;
FIG. 2 is a partial flow chart of a method of monitoring a pill making process for a pill making process according to an embodiment of the present application;
FIG. 3 is a logic diagram of judgment of adjustment mode selection in an embodiment of the present application;
FIG. 4 is a flow chart of signal processing in a method of monitoring a pill making process of a pill making process according to an embodiment of the present application;
FIG. 5 is a diagram illustrating selection of adjustment modes in an embodiment of the present application;
fig. 6 is a schematic diagram of a system for monitoring the pill making process of a pill making strip in accordance with an embodiment of the present application.
Detailed Description
In order to make the present application better understood by those skilled in the art, the technical solutions in the specific embodiments of the present application will be clearly and completely described with reference to the accompanying drawings in the embodiments of the present application.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. The terms "first," "second," "third," "fourth" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "first", "second", "third", and "fourth" may explicitly or implicitly include at least one such feature. As used in this specification and the appended claims, the singular forms "a," "an," and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise.
It should be noted that, the sequence number of each step in the embodiment of the present application does not mean that the execution sequence of each process should be determined by the function and the internal logic, and should not limit the implementation process of the embodiment of the present application.
The present application provides a method of monitoring the pelleting process of a pharmaceutical strip as shown in figure 1, the method comprising:
step S100: a first value of the bar is obtained.
Illustratively, the first numerical value of the drug strip includes at least any one of a diameter, a radius, a circumference, and/or a projected area of the drug strip, or a combination of the above.
In the embodiment of the application, the first value of the medicine strip is a measured value of the medicine strip, namely an actual value in the production process of the medicine strip. The device for detecting the first value of the strip may be a laser detection device, wherein the laser detection device comprises at least a laser emitter and a laser receiver. The laser beam emitted by the laser emitter passes through the medicine strip, and the laser receiver receives a part of the laser beam which is not shielded by the medicine strip, so that a first numerical value of the medicine strip is determined.
It should be noted that, because the diameter of the medicine strip is smaller, the detection accuracy of the relevant value of the medicine strip is higher, and in particular, the value of the medicine strip directly influences the medicine content of each prepared pill. In the related art, it is common to determine whether each pill or the same production lot of pills meets the specifications by manually detecting or detecting the number and size of the pills produced. However, the above method results in inaccurate detection results, and particularly for pills with smaller volumes, it is difficult to distinguish whether the pills conform to the specification by means of manual detection. On the other hand, by detecting the numerical value of the pill, although the detection result is more accurate than that of manual detection, if the pill does not meet the specification, the pill is removed, so that the yield is low and the resource waste is caused.
Compared with a manual detection method, the method for monitoring the pill making process of the medicine strips has higher detection precision, and can adjust the first numerical value of the medicine strips in time before pill making, thereby avoiding waste of medicine materials and production resources.
As shown in fig. 1, the method further includes step S200: and determining the deviation amount of the extruded medicine strip according to the first numerical value of the medicine strip and the second numerical value of the preset medicine strip.
The second numerical value of the medicine strip at least comprises the diameter, the radius, the perimeter and/or the projection area of the medicine strip, and the preset second numerical value corresponds to the numerical type of the first numerical value; the second numerical value is a standard value of the medicine strip, and the second numerical value is used for measuring whether the prepared medicine strip meets corresponding standards.
In this embodiment, if the laser detection device detects that the first value of the medicine strip is the actual diameter of the medicine strip, the second value is expressed as the target diameter of the medicine strip, and the deviation amount of the medicine strip is determined to be the diameter difference by the difference between the first value and the second value. It can be understood that if the laser detection device detects that the first value of the medicine strip is the actual projection area of the medicine strip, the second value is expressed as the target projection area of the medicine strip, and the deviation amount of the medicine strip is determined as the projection area difference by the difference value of the first value and the second value. The above arrangements do not indicate that the first and second values can be only diameters, radii, circumferences and/or projected areas, the above are only preferred embodiments of a method of monitoring a pill making process of a pill. Other parameters that may be used to measure whether the drug strip meets the specification or not, or parameters of the drug strip that can be obtained by the laser detection device, are within the scope of the present application, and are not described herein.
As shown in fig. 1, the method further includes step S300: and controlling the pharmaceutical equipment to adjust the first numerical value of the extruded medicine strip according to the deviation amount of the medicine strip.
It should be noted that, although the steps in the above-described flow or the flow chart of the drawings show a logical order, in some cases, the steps shown or described may be performed in an order different from that here.
As shown in fig. 2, step S300 specifically includes:
step S301: a control amount for adjusting the pharmaceutical equipment is determined based on the deviation amount of the medicine strip.
Illustratively, the laser detection device obtains the deviation amount of the drug strip and encapsulates the deviation amount of the drug strip into a detection signal for transmission to a controller, wherein the controller is a PID controller (Proportion Integration Differentiation, proportional-integral-derivative controller). The PID controller has the characteristics of high response speed and high precision, and the medicine strip extrusion process is in a continuous conveying state, the deviation of medicine strip indexes can be responded rapidly through the combination of the proportional, integral and differential actions of the PID controller, and the indexes of the medicine strips are stabilized at a preset second numerical value by timely adjusting the parameters of pharmaceutical equipment, so that the stable operation of the medicine strip production process is facilitated, and the resource waste is avoided.
In the present embodiment, the control amount satisfies the following relational expression:
；
wherein ,for controlling quantity, ++>For constant controller bias, +.>Is a proportional action coefficient, ++>For integral action coefficient, +.>For differentiating action coefficient, ++>Is->Deviation of the time bar.
Step S302: and determining a pressure threshold of the pharmaceutical equipment according to the control quantity.
In this embodiment, the adjustment of the pressure threshold of the pharmaceutical equipment can be achieved by controlling the rotational speed and feeding speed of its screw.
By way of example, increasing the screw speed of a pharmaceutical device increases the rate of delivery of material in the cavity of the pharmaceutical device, thereby increasing the pressure threshold at the exit of the pharmaceutical device, and the extruded drug strip expands after passing through the exit, thereby increasing the first value of the drug strip.
Illustratively, decreasing the rotational speed of the screw of the pharmaceutical device decreases the rate of delivery of the material in the cavity of the pharmaceutical device, thereby decreasing the pressure threshold at the exit of the pharmaceutical device, and the extruded drug strip contracts after passing through the exit such that the first value of the drug strip decreases.
Illustratively, by increasing the feed rate, the amount of material in the cavity of the pharmaceutical device is increased, the extrusion action between the screw and the material is enhanced, and the pressure threshold in the cavity is also increased, which has a similar effect as changing the screw speed. It will be appreciated that by reducing the feeding speed, the first value of the drug strip extruded from the strip outlet is reduced, and will not be described in detail herein.
Through the arrangement, the deviation between the first numerical value and the second numerical value of the medicine strip is reduced, control logic is simpler, and complex improvement on existing equipment is not needed.
Step S302: determining a pressure threshold of the pharmaceutical equipment according to the control quantity, specifically comprising:
according to the preset adjusting interval, if the control quantity is in the preset adjusting interval, the first numerical value of the medicine strip is adjusted by controlling the screw rotating speed of the pharmaceutical equipment to adjust the pressure threshold.
Illustratively, a preset adjustment interval is stored in the controller for selecting an adjustment mode of the pharmaceutical equipment (e.g., an adjustment mode of the pharmaceutical equipment by controlling a screw speed or a feeding speed). On the one hand, under the condition that the deviation between the first numerical value and the second numerical value of the medicine strip is smaller, the pressure threshold value in the pharmaceutical equipment is adjusted by controlling the rotating speed of the screw rod, so that the pressure threshold value adjusting device has higher adjusting precision. On the other hand, under the condition that the deviation between the first numerical value and the second numerical value of the medicine strip is larger, the pressure threshold value in the pharmaceutical equipment is adjusted by controlling the feeding speed, and the response speed of the first numerical value adjustment of the medicine strip is faster, so that the waste of the medicine strip is reduced.
In this embodiment, if the control amount is outside the adjustment interval according to the preset adjustment interval, the first value of the medicine strip is adjusted by controlling the feeding speed of the pharmaceutical equipment to adjust the pressure threshold.
A schematic flow chart of the adjustment mode of the selected pharmaceutical equipment may be shown in fig. 3.
As shown in fig. 4, by way of example, assuming that the second value of the medicine strip is the diameter of the medicine strip, the second value is set to 5mm, and the pid controller (p=2, i=4, d=1) outputs the control amount by performing proportional, integral and differential calculation on the deviation amount according to the deviation amount between the first value and the second value of the actual medicine strip acquired by the laser detection apparatus. When the control quantity of the PID controller is more than-0.4 and less than 0.4, controlling a first numerical value of the pharmaceutical strip by adjusting the rotating speed of the screw; when the output quantity of the PID controller is more than or equal to minus 1 and less than or equal to minus 0.4, controlling a first numerical value of the pharmaceutical strip by adjusting the feeding speed; when the output quantity of the PID controller is more than or equal to 0.4 and less than or equal to 1, the first numerical value of the pharmaceutical strip is controlled by adjusting the feeding speed.
In summary, the first numerical value of the medicine strip is monitored in real time, and the rotating speed and the feeding speed of the screw are adjusted according to the monitoring result, so that the first numerical value of the extruded medicine strip is kept basically equal to the preset second numerical value, and the quality and the stability of the medicine strip are ensured.
As shown in fig. 5, in an embodiment of the present application, the method further includes:
step S400: and performing filtering operation on the first numerical value of the medicine strip to filter out periodic interference noise of the first numerical value of the medicine strip.
By way of example, since the first value of the medication stripe is not changed in a large amount, the accuracy of the control of the pharmaceutical equipment can be improved by filtering out the periodic interference noise of the first value of the medication stripe.
Step S500: and packaging the first numerical value of the medicine strip into a detection signal, amplifying the detection signal, and transmitting the amplified detection signal to the controller.
Step S600: and displaying a numerical change curve of the medicine strip on a display interface of the controller according to the amplified detection signal.
It should be noted that, since the first value of the medicine strip is generally smaller, the variation curve of the first value of the medicine strip is not obvious during a detection period, particularly during the process of making small-particle pills. In order to avoid the situation that the change trend of the medicine strip cannot be intuitively observed on the display interface of the controller, the detection signal is amplified, so that the numerical change curve of the medicine strip can be clearly observed on the display interface of the controller, and an operator can conveniently and timely adjust the pharmaceutical equipment.
As shown in fig. 6, the present application also provides a system for monitoring a pill making process of a pill making strip, the system comprising:
the pharmaceutical equipment 11 is used for processing materials and preparing the materials into medicine strips; the pharmaceutical apparatus 11 comprises a strip outlet from which the manufactured drug strip is extruded.
The detection module 12, the detection module 12 is configured to detect a first value of the medicine strip, where the first value includes at least one or any combination of the following: the diameter, radius, perimeter, projection area, etc. of the medicine strip; the detection module 12 encapsulates the first value of the drug strip into a detection signal.
Illustratively, the detection module 12 includes at least one and any combination of the following: a laser transmitter 121 and a laser receiver 122, which are arranged on both sides of the strip, respectively.
The control module 13, the control module 13 is connected with the detection module 12, and control module 13 is used for obtaining detection signal, is provided with the second numerical value of medicine strip in the control module 13, and the second numerical value of medicine strip corresponds with first numerical value. The control module 13 determines the deviation amount of the medicine strip according to the first and second values of the medicine strip, and determines the control amount for adjusting the pharmaceutical equipment 11 according to the deviation amount of the medicine strip; wherein the control module 13 is a PID controller.
Optionally, control module 13 determines a pressure threshold for pharmaceutical facility 11 based on the control amount.
Specifically, the control module 13 includes a judgment unit. The control module 13 stores preset adjustment intervals for selecting different adjustment modes, and the judging unit is used for judging whether the control quantity is in the preset adjustment interval.
For example, if the judging unit judges that the control amount is within the preset adjustment interval, the control module 13 adjusts the pressure threshold in the inner cavity of the pharmaceutical equipment 11 by controlling the screw speed of the pharmaceutical equipment 11, thereby adjusting the first value of the medicine strip extruded from the strip outlet 111 so that the first value and the second value of the medicine strip are substantially equal.
For example, if the judging unit judges that the control amount is outside the preset adjustment interval, the control 13 adjusts the pressure threshold in the inner cavity of the pharmaceutical equipment 11 by controlling the feeding speed of the pharmaceutical equipment 11, thereby adjusting the first value of the medicine strip extruded from the strip outlet 111 so that the first value and the second value of the medicine strip are substantially equal.
Optionally, the system further comprises an amplifying module 14, and the detection signal generated by the detecting module 12 is amplified by the amplifying module 14 and then transmitted to the control module 13. Thereby ensuring the accuracy of monitoring the medicine strip.
Through the arrangement, the control precision of the medicine strip is improved, compared with the prior art, the cost for adjusting the first numerical value of the medicine strip is lower, and the quality of a product is higher.
It will be understood that modifications and variations will be apparent to those skilled in the art from the foregoing description, and it is intended that all such modifications and variations be included within the scope of the following claims.
Claims (10)
1. A method for monitoring the pill making process of a medicine strip is characterized in that,
the method comprises the following steps:
obtaining a first value of a drug strip, wherein the first value comprises at least one of: the diameter, radius and circumference of the medicine strip;
determining the deviation amount of the extruded medicine strip according to the first numerical value of the medicine strip and the preset second numerical value of the medicine strip;
and controlling pharmaceutical equipment to adjust the first numerical value of the extruded medicine strip according to the deviation amount of the medicine strip.
2. The method of claim 1, wherein controlling the pharmaceutical device to adjust the first value of the extruded drug strip based on the amount of deviation of the drug strip comprises:
determining a control amount for adjusting the pharmaceutical equipment according to the deviation amount of the medicine strip;
and adjusting the pressure threshold of the pharmaceutical equipment according to the control quantity.
3. The method of claim 2, wherein adjusting the pressure threshold of the pharmaceutical equipment according to the control amount comprises:
and according to a preset adjusting interval, if the control quantity is in the preset adjusting interval, adjusting the pressure threshold value by controlling the screw rotating speed of the pharmaceutical equipment, so as to adjust the first numerical value of the medicine strip.
4. A method according to claim 3, wherein controlling the pharmaceutical apparatus to adjust the first value of the extruded drug strip according to the amount of deviation of the drug strip comprises:
and according to the preset adjusting interval, if the control quantity is outside the adjusting interval, adjusting the pressure threshold value by controlling the feeding speed of the pharmaceutical equipment so as to adjust the first numerical value of the medicine strip.
5. The method of claim 2, wherein determining a control amount for adjusting the pharmaceutical equipment based on the deviation amount of the drug strip comprises:
the control amount satisfies the following relation:
；
wherein ,for the control amount, ++>Is a proportional action coefficient, ++>For integral action coefficient, +.>As a coefficient of differential action,for constant controller bias, +.>Is->The amount of deviation of the strip of medicine at the moment.
6. The method according to claim 1, characterized in that the method comprises:
and performing filtering operation on the first numerical value of the medicine strip to filter out periodic interference noise of the first numerical value of the medicine strip.
7. The method according to claim 1, characterized in that the method comprises:
packaging the first numerical value of the medicine strip into a detection signal, amplifying the detection signal, and transmitting the detection signal to a controller;
and displaying a numerical change curve of the medicine strip on a display interface of the controller according to the amplified detection signal.
8. A system for monitoring a pill making process of a pill comprising:
the pharmaceutical equipment comprises a strip outlet, and the medicine strip pressed and formed by the pharmaceutical equipment is extruded from the strip outlet;
characterized in that the system further comprises:
the detection module is used for detecting the first numerical value of the medicine strip, and the detection module packages the first numerical value of the medicine strip into a detection signal;
the control module is connected with the detection module and used for acquiring the detection signal, and a second numerical value of the medicine strip is preset by the control module; the control module determines the deviation amount of the medicine strip according to the first value and the second value of the medicine strip, determines the control amount for adjusting the pharmaceutical equipment according to the deviation amount of the medicine strip, and determines the pressure threshold of the pharmaceutical equipment according to the control amount.
9. The system of claim 8, wherein the detection module comprises at least one and any combination of: the laser transmitter and the laser receiver are respectively arranged at two sides of the medicine strip.
10. The system of claim 8, wherein the control module further comprises:
the judging unit is used for judging whether the control quantity is in a preset adjusting interval or not, and if the control quantity is in the adjusting interval, the control module adjusts the first numerical value of the medicine strip by controlling the screw speed of the pharmaceutical equipment; and if the control quantity is outside the regulation interval, the control module regulates the first numerical value of the medicine strip by controlling the feeding speed of the pharmaceutical equipment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311140205.5A CN116880160A (en) | 2023-09-06 | 2023-09-06 | Method and system for monitoring pill making process of medicine strips |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202311140205.5A CN116880160A (en) | 2023-09-06 | 2023-09-06 | Method and system for monitoring pill making process of medicine strips |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN116880160A true CN116880160A (en) | 2023-10-13 |
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| CN202311140205.5A Pending CN116880160A (en) | 2023-09-06 | 2023-09-06 | Method and system for monitoring pill making process of medicine strips |
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Cited By (1)
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| CN117215251A (en) * | 2023-11-07 | 2023-12-12 | 烟台卫康动物保健品有限公司 | Energy efficiency optimization control system and method in automatic pharmaceutical process |
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