CN116850249A - Foot soaking bag with cold dispelling and dampness eliminating effects - Google Patents
Foot soaking bag with cold dispelling and dampness eliminating effects Download PDFInfo
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- CN116850249A CN116850249A CN202311082274.5A CN202311082274A CN116850249A CN 116850249 A CN116850249 A CN 116850249A CN 202311082274 A CN202311082274 A CN 202311082274A CN 116850249 A CN116850249 A CN 116850249A
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/232—Angelica
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Abstract
The invention discloses a foot soaking bag with the effects of dispelling cold and eliminating dampness, and relates to the technical field of external traditional Chinese medicine preparations, wherein the foot soaking bag comprises an external packaging bag, an internal packaging bag and traditional Chinese medicine powder, and the traditional Chinese medicine powder is prepared by mixing and crushing mugwort leaves, rhizoma atractylodis, radix angelicae, notopterygium root, cortex lycii radicis, aconite, fructus cnidii, cinnamon, alpinia japonica; the foot bath bag is convenient to use, can quickly leach the effective components of the traditional Chinese medicine in hot water, and can achieve good effects of dispelling cold and eliminating dampness while relieving fatigue.
Description
Technical field:
the invention relates to the technical field of traditional Chinese medicine external preparations, in particular to a foot bath bag with the effects of dispelling cold and eliminating dampness.
The background technology is as follows:
foot bath belongs to foot bath, belongs to one of the contents of foot treatment of traditional Chinese medicine, and is also a common external treatment method. The feet are also called as the second heart of the human body, and research proves that the reflecting areas and the meridian distribution corresponding to the viscera organs exist on the feet of the human body, and when the feet are soaked with warm water, the reflecting areas can be stimulated, the blood circulation of the human body is promoted, the endocrine system is conditioned, the functions of the organs of the human body are enhanced, and the health care effects of preventing and curing diseases are obtained. Meanwhile, the warm water has a function of thermal stimulation on peripheral nerves of feet when the feet are soaked, and can inhibit cerebral cortex, so that people feel comfortable and relaxed to feel comfortable and easy to sleep, and sleep is deepened.
At present, a plurality of foot soaking bags with health care effects are available in the market, and although a plurality of traditional Chinese medicines are added, the effects are poor, and effective treatment effects are difficult to obtain. And different traditional Chinese medicine formulas are known to have different medicinal effects, so that a good effect of relieving or even curing a certain symptom is achieved in a targeted manner, and a specific traditional Chinese medicine formula is required to be selected. The invention aims to provide the foot soaking bag with the cold dispelling and dampness eliminating effects, and the foot soaking bag can play a prominent role in cold dispelling and dampness eliminating through an external application mode of soaking feet.
The invention comprises the following steps:
the invention aims to solve the technical problem of providing the foot bath bag with the effects of dispelling cold and eliminating dampness, and the foot bath bag adopts the traditional Chinese medicine composition with specific proportion, can quickly leach out active ingredients in hot water, and can play a good role in dispelling cold and eliminating dampness while relieving fatigue.
The technical problems to be solved by the invention are realized by adopting the following technical scheme:
the invention provides a foot soaking bag with the effects of dispelling cold and eliminating dampness, which comprises an outer packaging bag, an inner packaging bag and traditional Chinese medicine powder, wherein the traditional Chinese medicine powder is prepared by mixing and crushing mugwort leaves, rhizoma atractylodis, radix angelicae, notopterygium root, cortex cinnamomi, aconite, fructus cnidii, cinnamon, alpinia japonica and pepper.
Preferably, the mass ratio of the mugwort leaf, the rhizoma atractylodis, the angelica dahurica, the notopterygium root, the cortex lycii radicis, the aconite, the fructus cnidii, the cinnamon, the alpinia japonica is (20-30): (10-20): (5-10): (1-5).
Preferably, the outer packaging bag is a plastic or aluminum plastic packaging bag. Isolating moisture and oxygen in air, and preventing moisture absorption and oxidation deterioration of the Chinese medicinal powder.
Preferably, the inner packaging bag is a non-woven bag. The pore diameter of the non-woven bag is selected so that the Chinese medicinal powder can not permeate but allows water to permeate.
Preferably, the granularity of the traditional Chinese medicine powder is 0.3-1 mm. The granularity is too large, and the dissolution rate of the effective components of the traditional Chinese medicine is slow; the particle size is too small, the specific surface area is increased, the particles are easy to adsorb and agglomerate, and the dissolution rate of the effective components of the traditional Chinese medicine is also influenced.
Preferably, the weight of the traditional Chinese medicine powder is 10-30 g. The dosage of the traditional Chinese medicine powder in each bag of foot soaking bag is controlled, so that the cost is reduced while the drug effect is ensured, and the waste of traditional Chinese medicine is avoided.
Mugwort leaf: pungent and bitter taste and warm nature, has the effects of warming channels to stop bleeding, dispelling cold to stop pain, eliminating dampness and relieving itching.
Rhizoma atractylodis: bitter in taste and warm in nature, has the effects of eliminating dampness and strengthening spleen, dispelling wind-damp and improving eyesight.
Radix angelicae: pungent and warm in nature, has the effects of dispelling wind, eliminating dampness, relieving swelling and pain.
Notopterygium root: pungent and bitter taste and warm nature, has the effects of relieving exterior syndrome, dispelling cold, dispelling wind, eliminating dampness and relieving pain.
Cortex Periplocae Radicis: pungent and bitter taste and warm nature, has the effects of dispelling wind-damp, inducing diuresis to alleviate edema and strengthening tendons and bones.
Radix Aconiti lateralis Preparata: pungent and sweet in flavor, and warm in nature, has the effects of tonifying fire, supporting yang, dispelling cold and relieving pain.
Fructus Cnidii: pungent and bitter taste, warm nature and has the effects of dispelling cold, dispelling wind, eliminating dampness and relieving itching.
Cinnamon: pungent and sweet in flavor, warm in nature and hot in nature, has the effects of dispelling cold and relieving pain, warming channel and activating blood.
Alpinia galanga (L.) Offic: pungent in flavor and warm in nature, has the effects of dispelling cold and eliminating dampness, regulating qi and dredging collaterals.
Pricklyash peel: pungent in flavor and warm in nature, has the effects of warming middle energizer to dispel cold, removing dampness and relieving pain.
The invention provides a foot soaking bag with the effects of dispelling cold and eliminating dampness, which comprises an outer packaging bag, an inner packaging bag and a content, wherein the content is a mixture of traditional Chinese medicine powder and a dispersing agent, and the traditional Chinese medicine powder is prepared by mixing and crushing mugwort leaves, rhizoma atractylodis, radix angelicae, notopterygium root, cortex mori radicis, aconite, fructus cnidii, cinnamon, rhizoma alpiniae oxyphyllae and pepper.
Preferably, the dispersing agent is polyethylene glycol 400. Polyethylene glycol 400 is in powder form, and can be uniformly dispersed in the Chinese medicinal powder to reduce adsorption force among Chinese medicinal powder particles and improve fluidity of the Chinese medicinal powder.
Preferably, the mass ratio of the traditional Chinese medicine powder to the dispersing agent is 100 (10-20). If it is
The invention solves the problem of easy agglomeration of the traditional Chinese medicine powder after water absorption by adding the dispersing agent, and accelerates the dissolution speed of the effective components, thereby improving the utilization rate of the traditional Chinese medicine in the same foot soaking time.
Preferably, the mass ratio of the mugwort leaf, the rhizoma atractylodis, the angelica dahurica, the notopterygium root, the cortex lycii radicis, the aconite, the fructus cnidii, the cinnamon, the alpinia japonica is (20-30): (10-20): (5-10): (1-5).
Preferably, the outer packaging bag is a plastic or aluminum plastic packaging bag.
Preferably, the inner packaging bag is a non-woven bag.
Preferably, the granularity of the traditional Chinese medicine powder is 0.3-1 mm.
Preferably, the weight of the traditional Chinese medicine powder is 10-30 g.
The invention provides a foot soaking bag with the effects of dispelling cold and eliminating dampness, which comprises an outer packaging bag, an inner packaging bag and a content, wherein the content is a mixture of Chinese medicinal powder and a dispersing agent, and the Chinese medicinal powder is prepared by mixing and crushing mugwort leaves, qiu Mudan roots, radix angelicae, notopterygium roots, cortex caryophylli, aconite, fructus cnidii, cinnamon, alpinia japonica.
Preferably, the mass ratio of the mugwort leaves to the Qiu Mudan roots to the angelica dahurica to the notopterygium roots to the cortex lycii radicis to the aconite, the cnidium monnieri, the cinnamon to the alpinia japonica is (20-30): (10-20): (5-10): (1-5) to (1-5).
Preferably, the dispersing agent is polyethylene glycol 400.
Preferably, the mass ratio of the traditional Chinese medicine powder to the dispersing agent is 100 (10-20).
Preferably, the outer packaging bag is a plastic or aluminum plastic packaging bag.
Preferably, the inner packaging bag is a non-woven bag.
Preferably, the granularity of the traditional Chinese medicine powder is 0.3-1 mm.
Preferably, the weight of the traditional Chinese medicine powder is 10-30 g.
The disclosed medicinal effects (disinsection, heat clearing and detoxifying) of the root of the autumn peony do not contain the effects of dispelling cold and dispelling dampness, but the effects of dispelling cold and dispelling dampness of the foot bath bag prepared by replacing the rhizoma atractylodis do not decrease, and the better effects of dispelling cold and dispelling dampness are obtained. Therefore, the combination of the autumn peony root, the 9 traditional Chinese medicines such as the mugwort leaf and the angelica dahurica can produce unexpected technical effects through the specific proportion, and the unexpected technical effects refer to substantial improvement of the cold dispelling and dampness eliminating effects of the traditional Chinese medicine formula. .
The beneficial effects of the invention are as follows: the invention adopts the traditional Chinese medicine composition with specific proportion as traditional Chinese medicine powder after being mixed and crushed, and ensures the leaching of the effective components of the traditional Chinese medicine and prevents the traditional Chinese medicine from moisture absorption and oxidative deterioration in the storage process by a double-layer packaging mode; the foot bath bag prepared by the invention is convenient to use, can quickly leach out the effective components of the traditional Chinese medicine in hot water, can play a good role in dispelling cold and eliminating dampness while relieving fatigue, and can solve the side effects of gastrointestinal adverse reaction, toxic reaction, allergic skin reaction and the like of the oral traditional Chinese medicine.
The specific embodiment is as follows:
the invention is further described in connection with the following embodiments in order to make the technical means, the creation features, the achievement of the purpose and the effect of the invention easy to understand.
The nonwoven bags in the following examples and comparative examples were purchased from the Donghui nonwoven mill in the well-established city, and the polypropylene bags were purchased from Yitong packaging products Co., ltd in the Buddha city.
The equipment for pulverizing the traditional Chinese medicine and the pulverizing process parameters in the following examples and comparative examples are identical, and the equipment for mixing the traditional Chinese medicine and the dispersing agent and the mixing process parameters are also identical.
Example 1
The preparation method comprises the steps of fully mixing and crushing mugwort leaves, rhizoma atractylodis, angelica dahurica, notopterygium root, cortex cinnamomi, aconite, fructus cnidii, cinnamon, alpinia japonica and pepper according to the mass ratio of 25:18:15:10:8:6:7:6:4:3, preparing traditional Chinese medicine powder with the granularity of 0.3-1 mm, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain foot soaking bags containing 20g of traditional Chinese medicine powder in each bag.
Example 2
The preparation method comprises the steps of fully mixing and crushing mugwort leaves, rhizoma atractylodis, angelica dahurica, notopterygium root, cortex cinnamomi, aconite, fructus cnidii, cinnamon, alpinia japonica and pepper according to the mass ratio of 20:20:15:8:10:8:6:6:3:4, preparing traditional Chinese medicine powder with the granularity of 0.3-1 mm, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain foot soaking bags containing 20g of traditional Chinese medicine powder in each bag.
Example 3
The preparation method comprises the steps of fully mixing and crushing mugwort leaves, rhizoma atractylodis, radix angelicae, notopterygium roots, cortex cinnamomi, aconite, fructus cnidii, cinnamon, alpinia japonica and pepper according to the mass ratio of 25:15:20:10:5:5:7:8:5:3, preparing traditional Chinese medicine powder with the granularity of 0.3-1 mm, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain foot soaking bags containing 20g of traditional Chinese medicine powder in each bag.
Example 4
The preparation method comprises the steps of fully mixing and crushing mugwort leaves, rhizoma atractylodis, radix angelicae, notopterygium roots, cortex cinnamomi, aconite, fructus cnidii, cinnamon, alpinia japonica and pepper according to the mass ratio of 30:10:15:5:10:7:5:10:4:5, and then grinding the mixture into traditional Chinese medicine powder with the granularity of 0.3-1 mm, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain foot soaking bags containing 20g of traditional Chinese medicine powder in each bag.
Example 5
The preparation method comprises the steps of fully mixing and crushing mugwort leaves, rhizoma atractylodis, radix angelicae, notopterygium roots, cortex cinnamomi, aconite, fructus cnidii, cinnamon, alpinia japonica and pepper according to the mass ratio of 20:20:20:10:5:10:10:6:5:5:2, preparing traditional Chinese medicine powder with the granularity of 0.3-1 mm, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain foot soaking bags containing 20g of traditional Chinese medicine powder in each bag.
Example 6
Example 6 is different from example 5 in that polyethylene glycol 400 is added as a dispersing agent to the powder of the Chinese medicine.
Fully mixing and crushing the mugwort leaf, the rhizoma atractylodis, the angelica dahurica, the notopterygium root, the cortex lycii radicis, the aconite, the fructus cnidii, the cinnamon, the alpinia japonica and the pepper according to the mass ratio of 20:20:20:10:5:10:6:5:5:2, then crushing the mixture into traditional Chinese medicine powder with the granularity of 0.3-1 mm, uniformly mixing the traditional Chinese medicine powder with polyethylene glycol 400 according to the mass ratio of 100:10, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain the foot soaking bag containing 20g of traditional Chinese medicine powder.
Example 7
Example 7 is different from example 5 in that polyethylene glycol 400 is added as a dispersing agent to the powder of the Chinese medicine.
Fully mixing and crushing the mugwort leaf, the rhizoma atractylodis, the angelica dahurica, the notopterygium root, the cortex lycii radicis, the aconite, the fructus cnidii, the cinnamon, the alpinia japonica and the pepper according to the mass ratio of 20:20:20:10:5:10:6:5:5:2, preparing traditional Chinese medicine powder with the granularity of 0.3-1 mm, uniformly mixing the traditional Chinese medicine powder with polyethylene glycol 400 according to the mass ratio of 100:15, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain the foot soaking bag containing 20g of traditional Chinese medicine powder.
Example 8
Example 8 is different from example 5 in that polyethylene glycol 400 is added as a dispersing agent to the powder of the Chinese medicine.
Fully mixing and crushing the mugwort leaf, the rhizoma atractylodis, the angelica dahurica, the notopterygium root, the cortex lycii radicis, the aconite, the fructus cnidii, the cinnamon, the alpinia japonica and the pepper according to the mass ratio of 20:20:10:5:10:6:5:5:2 to prepare traditional Chinese medicine powder with the granularity of 0.3-1 mm, uniformly mixing the traditional Chinese medicine powder with polyethylene glycol 400 according to the mass ratio of 100:20, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain the foot soaking bag containing 20g of traditional Chinese medicine powder.
Example 9
Example 9 differs from example 5 in that the root of autumn peony is used instead of rhizoma Atractylodis.
The preparation method comprises the steps of fully mixing and crushing mugwort leaves, qiu Mudan roots, angelica dahurica, notopterygium roots, cortex mori radicis, aconite, fructus cnidii, cinnamon, alpinia japonica and pepper according to the mass ratio of 20:20:20:10:5:10:6:5:5:2 into traditional Chinese medicine powder with the granularity of 0.3-1 mm, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain foot soaking bags containing 20g of traditional Chinese medicine powder in each bag.
Polyethylene glycol 400 is used as a dispersing agent, so that the problem of easy agglomeration of the traditional Chinese medicine powder after water absorption can be solved to a certain extent, but the effect is not obvious. Because polyethylene glycol 400 is easily dissolved in water, the traditional Chinese medicine powder can be agglomerated after polyethylene glycol 400 is dissolved, so that the dispersion effect with good durability is required to be obtained, and other dispersing agents are also required to be selected.
Preferably, the dispersant is a polyethylene glycol-terminated polycondensate prepared by polycondensation of polyethylene glycol 400 and 1, 3-bis (chloromethyl) -1, 3-tetramethyldisiloxane. According to the invention, the hydrophilicity of the polyethylene glycol 400 is weakened by introducing the disiloxane chain segment, the dispersion effect and dispersion durability of the polyethylene glycol 400 on the traditional Chinese medicine powder are improved, the problem that the traditional Chinese medicine powder is easy to agglomerate after absorbing water is better solved, and the leaching speed and leaching rate of the effective components of the traditional Chinese medicine can be improved while the traditional Chinese medicine powder is effectively prevented from agglomerating during foot soaking, so that the cold dispelling and dampness eliminating effects of the foot soaking bag are enhanced.
Synthesis of polyethylene glycol-terminated polycondensate a: adding 0.2mol of polyethylene glycol 400 and 0.1mol of 1, 3-bis (chloromethyl) -1, 3-tetramethyldisiloxane into tetrahydrofuran, stirring and dissolving completely, adding 0.2mol of triethylamine, heating to a boiling state, carrying out reflux reaction, stopping heating after TLC monitors that the 1, 3-bis (chloromethyl) -1, 3-tetramethyldisiloxane is completely reacted, naturally cooling to room temperature, washing with water for three times at normal temperature, filtering, drying filter residues at 80 ℃, crushing into fine powder, and sieving with a 100-mesh sieve to obtain a polyethylene glycol-terminated polycondensate A.
Synthesis of polyethylene glycol-terminated polycondensate B: adding 0.2mol of polyethylene glycol 400 and 0.1mol of diethyl ether into tetrahydrofuran, stirring and dissolving completely, adding 0.2mol of triethylamine, heating to a boiling state, carrying out reflux reaction, stopping heating after TLC monitors that the diethyl ether is reacted completely, naturally cooling to room temperature, washing with water at normal temperature for three times, filtering, drying filter residues at 80 ℃, crushing into fine powder, and sieving with a 100-mesh sieve to obtain the polyethylene glycol-terminated polycondensate B.
Example 10
Example 10 differs from example 6 in that polyethylene glycol 400 was replaced with polyethylene glycol-terminated polycondensate a as a dispersant.
Fully mixing and crushing the mugwort leaf, the rhizoma atractylodis, the angelica dahurica, the notopterygium root, the cortex lycii radicis, the aconite, the fructus cnidii, the cinnamon, the alpinia japonica and the pepper according to the mass ratio of 20:20:20:10:5:10:6:5:5:2 to prepare traditional Chinese medicine powder with the granularity of 0.3-1 mm, uniformly mixing the traditional Chinese medicine powder with the polyethylene glycol-terminated polycondensate A according to the mass ratio of 100:10, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain the foot soaking bag containing 20g of traditional Chinese medicine powder.
Comparative example 1
Comparative example 1 differs from example 6 in that polyethylene glycol 400 was replaced with polyethylene glycol-terminated polycondensate B as a dispersant.
Fully mixing and crushing the mugwort leaf, the rhizoma atractylodis, the angelica dahurica, the notopterygium root, the cortex lycii radicis, the aconite, the fructus cnidii, the cinnamon, the alpinia japonica and the pepper according to the mass ratio of 20:20:20:10:5:10:6:5:5:2 to prepare traditional Chinese medicine powder with the granularity of 0.3-1 mm, uniformly mixing the traditional Chinese medicine powder with the polyethylene glycol-terminated polycondensate B according to the mass ratio of 100:10, and then sequentially carrying out inner packaging and outer packaging by using a non-woven fabric bag and a polypropylene packaging bag to obtain the foot soaking bag containing 20g of traditional Chinese medicine powder.
550 patients with severe cold and damp disease (the main symptoms are hand and foot debilitation, hand and foot coolness and general ache) are randomly selected, the average of the patients is divided into 11 groups, 50 patients in each group are respectively half men and women, each group uses the foot soaking bags prepared in the above examples and comparative examples, one bag is used each time, feet are soaked each time for 30min (the foot soaking bags and the feet are simultaneously put into hot water at 40 ℃ for 7 days, 8 continuous treatment courses are provided, and the results are shown in table 1.
Judging curative effect:
and (3) curing: the symptoms completely disappeared;
improvement: the symptoms are obviously relieved;
the method is characterized in that: the symptoms were not significantly altered.
TABLE 1
Cure/example | Improvement/example | Unhealed/case | Total effective rate/% | Cure rate/% | |
Example 1 | 25 | 25 | 0 | 100 | 25 |
Example 2 | 27 | 22 | 1 | 98 | 27 |
Example 3 | 23 | 25 | 2 | 96 | 23 |
Example 4 | 26 | 23 | 1 | 98 | 26 |
Example 5 | 29 | 21 | 0 | 100 | 29 |
Example 6 | 32 | 17 | 1 | 98 | 32 |
Example 7 | 35 | 15 | 0 | 100 | 35 |
Example 8 | 36 | 14 | 0 | 100 | 36 |
Example 9 | 38 | 11 | 1 | 98 | 38 |
Example 10 | 40 | 10 | 0 | 100 | 40 |
Comparative example 1 | 34 | 15 | 1 | 98 | 34 |
The foregoing has shown and described the basic principles and main features of the present invention and the advantages of the present invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, and that the above embodiments and descriptions are merely illustrative of the principles of the present invention, and various changes and modifications may be made without departing from the spirit and scope of the invention, which is defined in the appended claims. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (9)
1. A foot soaking bag with the effects of dispelling cold and eliminating dampness comprises an outer packaging bag, an inner packaging bag and Chinese medicinal powder, and is characterized in that: the Chinese medicinal powder is prepared from folium Artemisiae Argyi, rhizoma Atractylodis, radix Angelicae Dahuricae, notopterygii rhizoma, cortex Periplocae Radicis, radix Aconiti lateralis Preparata, fructus Cnidii, cortex Cinnamomi, rhizoma Alpiniae Officinarum, and fructus Zanthoxyli by mixing and pulverizing.
2. The utility model provides a foot bath package with cold dispelling and damp eliminating effects, includes outer wrapping bag, interior wrapping bag and content, its characterized in that: the content is a mixture of Chinese medicinal powder and dispersing agent, wherein the Chinese medicinal powder is prepared by mixing and crushing mugwort leaf, rhizoma atractylodis, angelica dahurica, notopterygium root, cortex caryophylli, aconite root, fructus cnidii, cinnamon, rhizoma alpiniae oxyphyllae and pepper.
3. The foot bath bag with the efficacy of dispelling cold and eliminating dampness according to claim 1 or 2, wherein the foot bath bag is characterized in that: the mass ratio of the mugwort leaf, the rhizoma atractylodis, the angelica dahurica, the notopterygium root, the cortex lycii radicis, the aconite, the cnidium fruit, the cinnamon, the alpinia japonica and the pepper is (20-30): (10-20): (5-10): (5-5): (1-5).
4. The foot bath bag with the efficacy of dispelling cold and eliminating dampness according to claim 1 or 2, wherein the foot bath bag is characterized in that: the outer packaging bag is a plastic or aluminum plastic packaging bag.
5. The foot bath bag with the efficacy of dispelling cold and eliminating dampness according to claim 1 or 2, wherein the foot bath bag is characterized in that: the inner packaging bag is a non-woven fabric bag.
6. The foot bath bag with the efficacy of dispelling cold and eliminating dampness according to claim 1 or 2, wherein the foot bath bag is characterized in that: the granularity of the traditional Chinese medicine powder is 0.3-1 mm.
7. The foot bath bag with the efficacy of dispelling cold and eliminating dampness according to claim 1 or 2, wherein the foot bath bag is characterized in that: the weight of the traditional Chinese medicine powder is 10-30 g.
8. The foot bath bag with the efficacy of dispelling cold and eliminating dampness according to claim 2, wherein the foot bath bag is characterized in that: the dispersing agent is polyethylene glycol 400.
9. The foot bath bag with the efficacy of dispelling cold and eliminating dampness according to claim 2 or 8, wherein the foot bath bag is characterized in that: the mass ratio of the traditional Chinese medicine powder to the dispersing agent is 100 (10-20).
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Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105288567A (en) * | 2015-12-01 | 2016-02-03 | 骆志明 | Traditional Chinese medicine powder for foot bath and preparation method thereof |
CN107693758A (en) * | 2017-10-17 | 2018-02-16 | 嘉兴市中医医院 | Clearing damp cold dispelling Traditional Chinese medicine for steeping foot formula |
CN109663002A (en) * | 2019-02-22 | 2019-04-23 | 甘肃牧宇生物科技有限公司 | It is a kind of to dry except cold powder for dipping feet and preparation method thereof |
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105288567A (en) * | 2015-12-01 | 2016-02-03 | 骆志明 | Traditional Chinese medicine powder for foot bath and preparation method thereof |
CN107693758A (en) * | 2017-10-17 | 2018-02-16 | 嘉兴市中医医院 | Clearing damp cold dispelling Traditional Chinese medicine for steeping foot formula |
CN109663002A (en) * | 2019-02-22 | 2019-04-23 | 甘肃牧宇生物科技有限公司 | It is a kind of to dry except cold powder for dipping feet and preparation method thereof |
Non-Patent Citations (2)
Title |
---|
段红梅: "秋季中药泡脚防"小毛病"", 《上海中医药报》, pages 0004 * |
王之一: "泡脚水里加点"料"功效让你想不到", 《农村百事通》, no. 19, pages 53 - 54 * |
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