CN109044858A - A kind of Khotan jade talcum powder - Google Patents
A kind of Khotan jade talcum powder Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
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Abstract
The invention belongs to infant nursing articles fields, more particularly to a kind of Khotan jade talcum powder, Khotan jade talcum powder prepared by the present invention includes following parts by weight: 50-60 parts of Khotan jade Ultramicro-powder, 10-20 parts of gallnut extract, 5-10 parts of Asian puccoon volatile oil clathrate compound, 10-15 parts of aloe frozen-dried powder, 0.1-0.3 parts of menthol, 2-5 parts of borneol, 5-8 parts of zinc oxide, 3-6 parts of boric acid, 0.1-0.5 parts of essence, the present invention utilizes Khotan jade Ultramicro-powder and Chinese gall, Asian puccoon, aloe etc. has clearing heat and detoxicating, antalgesic-antipruritic, restrain the herbal powder of antiperspirant efficacy, and it is aided with menthol, borneol etc. helps skin to absorb, improve skin microcirculation, reach convergence hidroschesis, greasy skin, the effect of preventing prickly heat and eczema.
Description
Technical field
The present invention relates to a kind of child care products fields, and in particular to a kind of Khotan jade talcum powder.
Background technique
Often because perspiration causes to generate at the skinfolds such as summer arrives, and neck, oxter, femoribus internus, the elbow of infant is curved
A variety of skin diseases, such as: prickly heat, erosion, bleb, red stern.And talcum powder has as a kind of dry lubricant and removes sweat, dissipates
The effects of heat, dry, refreshing body, anti-miliaria, antipruritic, lubrication, child can be made to feel to feel nice and cool after putting on the skin, comfortably, cleaning, at present in city of China
Baby talcum powder is substantially to be prepared using talcum powder as raw material on field, and talcum powder is by oxidizing ferment, silica, magnesium silicate to tie
The inorganic compound of conjunction form composition, wherein magnesium silicate is exactly the asbestos that we usually say, is a kind of substance for easily inducing cancer,
It is easily accessible respiratory tract, causes respiratory disease, in addition, also containing inseparable lead in talcum powder, lead enters infants
It is inside not easy to drain, long-term product will endanger nerve, hematopoiesis and digestive system in human body.Chinese patent " a kind of rhizoma polygonati talcum powder and
Preparation method " (patent publication No.: CN107854338A) disclose one kind and can not only lubricate the skin and muscle, and sweat is absorbed, can more be driven
Worm sterilization, the talcum powder with aromatic odor, but the patent contains carcinogen talcum powder, and therefore, urgent need, which develops one kind, to be had
Lubricity, absorption of perspiration and talcum powder that is sterile, nontoxic, nonirritant, and being absorbed by the human body.
Summary of the invention
To solve the above-mentioned problems, the present invention provides a kind of Khotan jade talcum powder, Khotan jade Ultramicro-powder and five times are utilized
Son, Asian puccoon, aloe etc. have clearing heat and detoxicating, antalgesic-antipruritic, restrain the herbal powder of antiperspirant efficacy, and are aided with menthol, ice
The effect of piece etc. helps skin to absorb, and improves skin microcirculation, reaches convergence hidroschesis, greasy skin, prevention prickly heat and eczema.
The present invention can be achieved through the following technical solutions:
A kind of Khotan jade talcum powder includes following parts by weight of component: 50-60 parts of Khotan jade Ultramicro-powder, gallnut extract 10-20
Part, 5-10 parts of Asian puccoon volatile oil clathrate compound, 10-15 parts of aloe frozen-dried powder, 0.1-0.3 parts of menthol, 2-5 parts of borneol, zinc oxide
5-8 parts, 3-6 parts of boric acid, 0.1-0.5 parts of essence.
Preferably, the Khotan jade talcum powder includes following parts by weight of component: 52-58 parts of Khotan jade Ultramicro-powder, Chinese gall
12-18 parts of powder, 6-9 parts of Asian puccoon volatile oil clathrate compound, 11-13 parts of aloe frozen-dried powder, 0.15-0.25 parts of menthol, borneol 3-4
Part, 6-7 parts of zinc oxide, 4-5 parts of boric acid, 0.2-0.4 parts of essence.
Preferably, the Khotan jade talcum powder includes following parts by weight of component: 55 parts of Khotan jade Ultramicro-powder, gallnut extract 15
Part, 7 parts of Asian puccoon volatile oil clathrate compound, 12 parts of aloe frozen-dried powder, 0.2 part of menthol, 3.5 parts of borneol, 6.5 parts of zinc oxide, boric acid
4.5 parts, 0.3 part of essence.
Preferably, the Asian puccoon volatile oil clathrate compound the preparation method comprises the following steps:
A. it takes Asian puccoon to crushed 60 meshes, is then that n-hexane is added in 1:5 by solid-liquid ratio, is 20kHz, function in supersonic frequency
Under conditions of rate is 200W, ultrasonic continuous acts on 30min, and filtering takes filter residue to repeat ultrasonication 1 time, and filtering merges filter
Liquid takes filtrate to go out n-hexane solvent through rotary evaporation in vacuo, obtains Asian puccoon volatile oil；
B. it takes beta-cyclodextrin that water is added to dissolve by heating, when being cooled to 50 DEG C, Asian puccoon volatile oil is added and equivalent dehydrated alcohol is mixed
The mixed liquor of conjunction is placed in constant temperature in magnetic stirring apparatus and stirs 2h, be cooled to room temperature, is put into refrigerator and refrigerates for 24 hours, filter, successively
It is washed with distilled water, dehydrated alcohol, is then dried in vacuo 3h, obtain Asian puccoon volatile oil clathrate compound.
Preferably, the aloe frozen-dried powder the preparation method comprises the following steps: take fresh aloe, remove the peel, take gel to be homogenized, with 4 layers of yarn
Cloth filtering, takes filtrate to be placed in -50 DEG C of freeze-dryings and obtains freeze-dried powder, grinds, and crosses 120 meshes to get aloe frozen-dried powder.
The present invention also provides a kind of preparation methods of Khotan jade talcum powder, comprising the following steps:
(1) zinc oxide, borneol, boric acid were smashed and ground into 120 meshes respectively, be added Khotan jade Ultramicro-powder, gallnut extract,
Asian puccoon volatile oil clathrate compound and aloe frozen-dried powder, stir evenly；
(2) it takes menthol to be added in essence and is dissolved into mixed liquor；
(3) powder that step (1) obtains is put into mixing machine and is stirred, equably sprayed the mixed liquor of step (2), be allowed to
It is uniformly mixed with powder；
(4) powdery finished product described in step (3) is put into dryer and is dried, until powder moisture is less than 10%, then
It is ground into fine powder, sterilizes 3min at 100 DEG C to get Khotan jade talcum powder of the invention is arrived.
Preferably, in the step (4) powder particle size less than 10 μm.
Each main composition mechanism of action of the present invention is as follows:
Khotan jade is one of Chinese four big name jade, includes a large amount of microelement, the starting wave and people that these elements distribute
The starting wave of body cell is same fluctuation status, human body cell as the fluctuation given out from jade is empathized and is resonated,
So that human cell tissue is had more vigor, and blood is promoted to follow bad, enhancing metabolism, exclusion bodily waste.
The polysaccharide and multivitamin contained in aloe has good nutrition to human skin, moistens, whitening effect, tool
Having makes skin contraction, softness, the performance of moisturizing, anti-inflammatory, bleaching, there are also contact hardening, angling, improve scar effect, this
Outside, the ingredients such as isocitric acid calcium in aloe can expand capillary, promote microcirculation, strengthen cell viability, to sterilizing, disappear
Scorching, regenerated function is very brilliant, can effectively facilitate the recovery of skin and mucosa.
Asian puccoon is the dry root of comfrey Asian puccoon, and nature and flavor are sweet, salty, cold, has cooling and activating blood, and removing toxic substances promoting eruption acts on,
Can clearing away heat and eliminating dampeness, have restrain and protection skin and mucosa barrier action, make urine and sweat etc. be not easy to penetrate into skin, from
It damages again, is conducive to the Regeneration and Repair of pathological tissues.
After tannic acid contained by Chinese gall has precipitation, skin, mucosal ulcer to contact tannic acid in protein, histone
Matter is solidified, and is formed a tunic face and is played astriction, and gallnut extract also has an antibacterial action, gallnut extract have sterilization, promoting blood circulation,
Improve local nutrition condition, increases local zinc concentration and convergence, analgesic, reduces the effects of exudation.
The present invention have it is following the utility model has the advantages that
(1) using Khotan jade Ultramicro-powder as primary raw material in the present invention, contained a large amount of microelement can be inhaled by skin
It receives, activating cell tissue, improves immunity of organisms, and the undesirable substances such as impurity in hair follicle, neutral fat and sweat are discharged together,
It promotes blood circulation, adjusts autonomic nerve, make skin smooth, exquisiteness, high resilience；
(2) it is added to the gallnut extract with good convergence anti-hidropoiesis in the present invention, can restrain, relieve pain, reduce baby
Child's volume of perspiration, and also there are antibacterial and anti-inflammation functions, there is improvement and prevention effect well to children's ephidrosis, red hip；
(3) present invention uses ultrasound assisted extraction to Asian puccoon, and carries out clathrate process, greatly reservation Asian puccoon it is effective at
Point, it is applied in the preparation of talcum powder, there is clearing heat and detoxicating, detumescence convergence, hidroschesis analgesic, promote wound healing, antibacterial
The effects of anti-inflammatory；
(4) present invention extracts its gel and is freeze-dried from aloe, is prepared into freeze-dried powder and as talcum powder
Primary raw material, there is good nutrition to the skin of infant, moisten, moisturizing, whitening function；
(5) menthol and borneol be also added in talcum powder of the invention, the metabolism of skin, discharge poison can be promoted
Element makes prickly heat dissipate rapidly, and plays the role of detoxicating, relieving inflammation, antalgesic-antipruritic, to be effectively prevented and treated prickly heat.
Specific embodiment
In order to be easy to understand the technical means, the creative features, the aims and the efficiencies achieved by the present invention, tie below
Specific embodiment is closed, the present invention is further explained.
A kind of Khotan jade talcum powder embodiment 1-5 formula of the present invention is as shown in table 1:
Table 1
Above-mentioned Asian puccoon volatile oil clathrate compound the preparation method comprises the following steps:
A. it takes Asian puccoon to crushed 60 meshes, is then that n-hexane is added in 1:5 by solid-liquid ratio, is 20kHz, function in supersonic frequency
Under conditions of rate is 200W, ultrasonic continuous acts on 30min, and filtering takes filter residue to repeat ultrasonication 1 time, and filtering merges filter
Liquid takes filtrate to go out n-hexane solvent through rotary evaporation in vacuo, obtains Asian puccoon volatile oil；
B. it takes beta-cyclodextrin that water is added to dissolve by heating, when being cooled to 50 DEG C, Asian puccoon volatile oil is added and equivalent dehydrated alcohol is mixed
The mixed liquor of conjunction is placed in constant temperature in magnetic stirring apparatus and stirs 2h, be cooled to room temperature, is put into refrigerator and refrigerates for 24 hours, filter, successively
It is washed with distilled water, dehydrated alcohol, is then dried in vacuo 3h, obtain Asian puccoon volatile oil clathrate compound.
Above-mentioned aloe frozen-dried powder the preparation method comprises the following steps: take fresh aloe, remove the peel, gel taken to be homogenized, with 4 layers of filtered through gauze,
It takes filtrate to be placed in -50 DEG C of freeze-dryings and obtains freeze-dried powder, grind, cross 120 meshes to get aloe frozen-dried powder.
A kind of preparation method of above-mentioned Khotan jade talcum powder, comprising the following steps:
(1) zinc oxide, borneol, boric acid were smashed and ground into 120 meshes respectively, be added Khotan jade Ultramicro-powder, gallnut extract,
Asian puccoon volatile oil clathrate compound and aloe frozen-dried powder, stir evenly；
(2) it takes menthol to be added in essence and is dissolved into mixed liquor；
(3) powder that step (1) obtains is put into mixing machine and is stirred, equably sprayed the mixed liquor of step (2), be allowed to
It is uniformly mixed with powder；
(4) powdery finished product described in step (3) is put into dryer and is dried, until powder moisture is less than 10%, then
It is ground into fine powder, sterilizes 3min at 100 DEG C to get Khotan jade talcum powder of the invention is arrived.
Powder particle size is less than 10 μm in above-mentioned steps (4).
Efficacy validation
To the talcum powder of embodiment 1-5 group preparation in terms of powder, color, dispersibility, the white sense of skin, skin sense etc. five
Quality is evaluated, and 1 group of comparative example is Conventional body, and powder, color account for 10% ratio, and the white sense of skin accounts for 20% ratio, point
Scattered property, skin sense account for 30%, and scoring is with 1-10 points for standard, and the results are shown in Table 2:
The results of sensory evaluation of 2 each group talcum powder of table
| Group | Powder | Color | The white sense of skin | Dispersibility | Skin sense | Total score |
| Comparative example 1 | 7.1 | 7.2 | 4.5 | 4.1 | 4.4 | 4.88 |
| Embodiment 1 | 7.7 | 8.0 | 7.6 | 7.8 | 7.7 | 7.74 |
| Embodiment 2 | 7.9 | 8.1 | 7.8 | 8.0 | 7.8 | 7.90 |
| Embodiment 3 | 8.1 | 8.3 | 7.9 | 8.2 | 8.0 | 8.08 |
| Embodiment 4 | 8.0 | 8.2 | 7.7 | 8.1 | 7.9 | 7.96 |
| Embodiment 5 | 7.8 | 8.0 | 7.6 | 7.9 | 7.8 | 7.81 |
As can be seen from Table 2, difference is little on powder, color with embodiment 1-5 group for 1 group of comparative example, but white in skin
Bigger difference is showed in sense, dispersibility and skin sense, the white sense of 1 group of comparative example of Conventional body skin, dispersibility and skin sense are general
All over lower, and in embodiment 1-5 group, the talcum powder that 3 groups of embodiment is in powder, color, the white sense of skin, dispersibility and skin sense etc. five
A aspect, general effect are preferable.
The rabbit of healthy adult is selected, weight 2.2-2.4kg is 20-24 DEG C in temperature, and relative humidity is 50-70%'s
Under the conditions of, talcum powder is applied to the rabbit back of cropping, area 2.5cm*2.5cm is applied skin 1 time daily, continuous to apply skin 14
It, 2 groups of comparative example in rabbit backside distilled water, 3 groups of the comparative example talcum powders for containing talcum powder in rabbit backside, result
It is as shown in table 3:
Irritation of the 3 each group talcum powder of table to rabbit skin
As shown in Table 3, every animal integral mean value is 0.09 point daily for 2 groups of comparative example and embodiment 1-5 group, and comparative example
3 groups use the talcum powder containing talcum powder, and during applying skin, it is a lot of erythema, oedema situation occur, according to cosmetics health specification skin
Skin stimulus intensity grade scale, belongs to nonirritant product, illustrate bright Khotan jade talcum powder prepared by the present invention to rabbit skin without
Irritation.
It chooses 1 years old hereinafter, the baby with prickly heat, is randomly divided into 3 groups of embodiment and 4 groups of comparative example, 4 groups of comparative example is not
The talcum powder of the Ultramicro-powder containing Khotan jade equably applies one layer of talcum powder at prickly heat, and 1 time a day, the results are shown in Table 4:
4 each group talcum powder of table compares the therapeutic effect of prickly heat
As shown in Table 4, embodiment 1-5 group has good therapeutic effect to prickly heat, and in cure rate and total effective rate side
Face is above 4 groups of comparative example, has significant difference, illustrates that Khotan jade talcum powder prepared by the present invention can make prickly heat disappear rapidly
It dissipates, there is prevention and therapeutic effect to prickly heat.
In conclusion Khotan jade talcum powder prepared by the present invention belongs to nonirritant product, powder is fine and smooth clean, without miscellaneous
Matter, color homogeneous and bright have good dispersibility, are easier to smear on the skin uniformly, and without obvious whiting, have dry and comfortable
Sense, in addition, Khotan jade talcum powder prepared by the present invention also has the effects of antibacterial anti-inflammatory, convergence hidroschesis, antalgesic-antipruritic, to baby children
The symptoms such as the perspiration of youngster is more, red hip, eczema, prickly heat, which have, prevents and treatment improvement result.
The embodiments described above only express several embodiments of the present invention, and the description thereof is more specific and detailed, but simultaneously
Limitations on the scope of the patent of the present invention therefore cannot be interpreted as.It should be pointed out that for those of ordinary skill in the art
For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to guarantor of the invention
Protect range.
Claims (7)
1. a kind of Khotan jade talcum powder, which is characterized in that include following parts by weight of component: 50-60 parts, five times of Khotan jade Ultramicro-powder
Sub- powder 10-20 parts, 5-10 parts of Asian puccoon volatile oil clathrate compound, 10-15 parts of aloe frozen-dried powder, 0.1-0.3 parts of menthol, borneol 2-5
Part, 5-8 parts of zinc oxide, 3-6 parts of boric acid, 0.1-0.5 parts of essence.
2. a kind of Khotan jade talcum powder according to claim 1, which is characterized in that include following parts by weight of component: and field
Beautiful Ultramicro-powder 52-58 parts, 12-18 parts of gallnut extract, 6-9 parts of Asian puccoon volatile oil clathrate compound, 11-13 parts of aloe frozen-dried powder, peppermint
0.15-0.25 parts of brain, 3-4 parts of borneol, 6-7 parts of zinc oxide, 4-5 parts of boric acid, 0.2-0.4 parts of essence.
3. a kind of Khotan jade talcum powder according to claim 1 or 2, which is characterized in that include following parts by weight of component: and
55 parts of field jade Ultramicro-powder, 15 parts of gallnut extract, 7 parts of Asian puccoon volatile oil clathrate compound, 12 parts of aloe frozen-dried powder, 0.2 part of menthol, ice
3.5 parts of piece, 6.5 parts of zinc oxide, 4.5 parts of boric acid, 0.3 part of essence.
4. a kind of Khotan jade talcum powder according to claim 1-3, which is characterized in that the Asian puccoon volatile oil packet
Close object the preparation method comprises the following steps:
A. it takes Asian puccoon to crushed 60 meshes, is then that n-hexane is added in 1:5 by solid-liquid ratio, is 20kHz in supersonic frequency, power is
Under conditions of 200W, ultrasonic continuous acts on 30min, and filtering takes filter residue to repeat ultrasonication 1 time, filtering, merging filtrate,
It takes filtrate to go out n-hexane solvent through rotary evaporation in vacuo, obtains Asian puccoon volatile oil；
B. it takes beta-cyclodextrin that water is added to dissolve by heating, when being cooled to 50 DEG C, is added what Asian puccoon volatile oil was mixed with equivalent dehydrated alcohol
Mixed liquor is placed in constant temperature in magnetic stirring apparatus and stirs 2h, be cooled to room temperature, be put into refrigerator and refrigerate for 24 hours, filter, successively with steaming
Distilled water, dehydrated alcohol washing, are then dried in vacuo 3h, obtain Asian puccoon volatile oil clathrate compound.
5. a kind of Khotan jade talcum powder according to claim 1-3, which is characterized in that the aloe frozen-dried powder
The preparation method comprises the following steps: taking fresh aloe, removes the peel, take gel to be homogenized, with 4 layers of filtered through gauze, take filtrate to be placed in -50 DEG C and be freeze-dried
To freeze-dried powder, grinding crosses 120 meshes to get aloe frozen-dried powder.
6. the method for preparing a kind of Khotan jade talcum powder as described in any one in claim 1-5, which is characterized in that including following
Step:
(1) zinc oxide, borneol, boric acid were smashed and ground into 120 meshes respectively, Khotan jade Ultramicro-powder, gallnut extract, Asian puccoon is added
Volatile oil clathrate compound and aloe frozen-dried powder, stir evenly；
(2) it takes menthol to be added in essence and is dissolved into mixed liquor；
(3) powder that step (1) obtains is put into mixing machine and is stirred, equably sprayed the mixed liquor of step (2), be allowed to and powder
End is uniformly mixed；
(4) powdery finished product described in step (3) is put into dryer and is dried, until then powder moisture is ground less than 10%
At fine powder, 3min is sterilized at 100 DEG C to get Khotan jade talcum powder of the invention is arrived.
7. a kind of preparation method of Khotan jade talcum powder according to claim 6, which is characterized in that in the step (4)
Powder particle size is less than 10 μm.
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2018
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