CN116808121A - Antibacterial liquid for treating rheumatic osteodynia and preparation method thereof - Google Patents
Antibacterial liquid for treating rheumatic osteodynia and preparation method thereof Download PDFInfo
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- CN116808121A CN116808121A CN202311040691.3A CN202311040691A CN116808121A CN 116808121 A CN116808121 A CN 116808121A CN 202311040691 A CN202311040691 A CN 202311040691A CN 116808121 A CN116808121 A CN 116808121A
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- rheumatalgia
- antibacterial solution
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Abstract
The invention discloses a rheumatalgia antibacterial solution and a preparation method thereof, and relates to the technical field of medicine preparation. The invention comprises the following raw materials in parts by weight: 15-20 parts of ligusticum wallichii, 5-8 parts of stiff silkworm, 10-15 parts of asarum, 1-3 parts of ground beetle, 5-8 parts of prepared arisaema tuber, 3-5 parts of garden balsam stem, 3-5 parts of safflower, 5-8 parts of pseudo-ginseng, 3-5 parts of eucommia bark, 5-8 parts of astragalus root, 1-3 parts of frankincense, 1-3 parts of myrrh, 3-5 parts of scorpion, 3-5 parts of centipede, 3-5 parts of spatholobus stem, 1-3 parts of camphor, 1-3 parts of borneol, 1-3 parts of menthol and 1-3 parts of thymol. The antibacterial liquid has good effects of resisting bacteria, resisting inflammation, relieving pain and improving blood circulation by adding medicines such as ligusticum wallichii, stiff silkworm, asarum, ground beetle, prepared arisaema tuber, caulis spatholobi and the like, has an inhibiting effect on escherichia coli, staphylococcus aureus and candida albicans, and solves the problem that the traditional antibacterial liquid is not ideal in effects of resisting bacteria, resisting inflammation, relieving pain and improving blood circulation.
Description
Technical Field
The invention belongs to the technical field of medicine preparation, and in particular relates to a rheumatalgia antibacterial liquid and a preparation method thereof.
Background
The rheumatism bone disease is caused by invasion of wind-cold-dampness evil into human body, and after invasion of wind-cold-dampness evil into human body, the muscles and vessels are blocked, so that red swelling and pain are often caused at joints, periosteum, muscles and other parts of human body. The method for treating the rheumatic bone pain comprises western medicine treatment, physical treatment, massage acupuncture treatment, sealing therapy, operation treatment and the like, but the method has a plurality of defects, has great side effects and high cost, and can cause the pain of patients to be uncomfortable and hard for the patients. When treating rheumatalgia, physiotherapy methods such as local thermotherapy, hot water bath, steam therapy, etc. can be used, or oral administration and external application can be used.
The rheumatalgia-relieving antibacterial liquid is a liquid medicine for treating rheumatalgia and inhibiting bacterial infection. The rheumatalgia-relieving antibacterial liquid can permeate skin and muscle tissues to achieve the effect of inhibiting bacterial growth and reproduction and relieve the symptoms of rheumatalgia, has the effects of diminishing inflammation, easing pain, relieving swelling, dispelling cold and the like, and can effectively relieve and improve the symptoms of rheumatalgia such as rheumarthritis, hyperosteogeny and the like. However, the existing rheumatalgia antibacterial liquid still has the following defects in actual use: the existing antibacterial liquid has the defects of unsatisfactory effects of resisting bacteria, resisting inflammation, easing pain and improving blood circulation, and has relatively irritated smell and insufficient comfort for patients.
Therefore, the existing rheumatalgia-relieving antibacterial solution cannot meet the requirements in practical use, so that an improved technology is urgently needed in the market to solve the problems.
Disclosure of Invention
The invention aims to provide a rheumatalgia antibacterial solution and a preparation method thereof, and the antibacterial solution has good effects of resisting bacteria, resisting inflammation, easing pain and improving blood circulation by adding medicines such as ligusticum wallichii, stiff silkworm, asarum, ground beetle, prepared arisaema tuber, caulis spatholobi and the like, has an inhibition effect on escherichia coli, staphylococcus aureus and candida albicans, and solves the problem that the traditional antibacterial solution is not ideal in effects of resisting bacteria, resisting inflammation, easing pain and improving blood circulation.
In order to solve the technical problems, the invention is realized by the following technical scheme:
the invention relates to a rheumatalgia antibacterial solution which comprises the following raw materials in parts by weight: 15-20 parts of ligusticum wallichii, 5-8 parts of stiff silkworm, 10-15 parts of asarum, 1-3 parts of ground beetle, 5-8 parts of prepared arisaema tuber, 3-5 parts of garden balsam stem, 3-5 parts of safflower, 5-8 parts of pseudo-ginseng, 3-5 parts of eucommia bark, 5-8 parts of astragalus root, 1-3 parts of frankincense, 1-3 parts of myrrh, 3-5 parts of scorpion, 3-5 parts of centipede, 3-5 parts of spatholobus stem, 1-3 parts of camphor, 1-3 parts of borneol, 1-3 parts of menthol and 1-3 parts of thymol.
Further, the material comprises the following raw materials in parts by weight: 15 parts of ligusticum wallichii, 5 parts of stiff silkworm, 10 parts of asarum, 1 part of ground beetle, 5 parts of prepared rhizoma arisaematis, 3 parts of garden balsam stem, 3 parts of safflower, 5 parts of pseudo-ginseng, 3 parts of eucommia ulmoides, 5 parts of astragalus, 1 part of frankincense, 1 part of myrrh, 3 parts of scorpion, 3 parts of centipede, 3 parts of suberect spatholobus stem, 1 part of camphor, 1 part of borneol, 1 part of menthol and 1 part of thymol.
Further, the material comprises the following raw materials in parts by weight: 18 parts of ligusticum wallichii, 7 parts of stiff silkworm, 13 parts of asarum, 2 parts of ground beetle, 7 parts of prepared rhizoma arisaematis, 4 parts of garden balsam stem, 4 parts of safflower, 7 parts of pseudo-ginseng, 4 parts of eucommia ulmoides, 7 parts of astragalus membranaceus, 2 parts of frankincense, 2 parts of myrrh, 4 parts of scorpion, 4 parts of centipede, 4 parts of suberect spatholobus stem, 2 parts of camphor, 2 parts of borneol, 2 parts of menthol and 2 parts of thymol.
Further, the material comprises the following raw materials in parts by weight: 20 parts of ligusticum wallichii, 8 parts of stiff silkworm, 15 parts of asarum, 3 parts of ground beetle, 8 parts of prepared rhizoma arisaematis, 5 parts of garden balsam stem, 5 parts of safflower, 8 parts of pseudo-ginseng, 5 parts of eucommia ulmoides, 8 parts of astragalus, 3 parts of frankincense, 3 parts of myrrh, 5 parts of scorpion, 5 parts of centipede, 5 parts of suberect spatholobus stem, 3 parts of camphor, 3 parts of borneol, 3 parts of menthol and 3 parts of thymol.
The invention also provides a preparation method of the rheumatalgia antibacterial liquid, which is used for preparing the rheumatalgia antibacterial liquid and comprises the following steps:
s1: taking a proper amount of raw materials in parts by weight, respectively grinding the raw materials into powder, and adding the powder into a reaction kettle;
s2: adding proper amount of alcohol and water into a reaction kettle to completely soak the medicinal materials, fully stirring and mixing by adopting a stirrer to ensure that various components are uniformly distributed, and then soaking and fermenting for 15-20d;
s3: in the soaking process, a microwave heating assembly in the reaction kettle is started every day to heat the liquid medicine, and then an ultrasonic generating assembly in the reaction kettle is started to carry out ultrasonic treatment on the liquid medicine;
s4: filtering out the medicinal materials after fermentation is completed, retaining the medicinal liquid, and carrying out ultrasonic treatment on the filtered clear medicinal liquid;
s5: and (3) placing the ultrasonic-treated clear liquid medicine in a high-pressure environment for sterilization treatment, and then filling and packaging to obtain a finished product.
Further, the grinding particle size of each raw material in S1 was 400 mesh.
Further, the ratio of alcohol to water in S2 is set to 7:3.
Further, the heating temperature of the microwave heating component in the step S3 is 55-60 ℃, and the ultrasonic treatment time of the ultrasonic generating component is 8-10min.
The invention has the following beneficial effects:
1. according to the invention, medicines such as ligusticum wallichii, stiff silkworm, asarum, ground beeltle, prepared rhizoma arisaematis, speranskia herb, safflower, scorpion, centipede, caulis spatholobi and the like are added, so that the antibacterial liquid has good effects of resisting bacteria, diminishing inflammation, easing pain and improving blood circulation, has an inhibiting effect on escherichia coli, staphylococcus aureus and candida albicans, effectively relieves rheumatalgia, has good efficacy and comfortable feeling in use, and can treat the rheumatalgia in a short period of treatment.
2. The antibacterial liquid has good smell, is mild and does not irritate, and can give off faint scent, and has the effects of refreshing, purifying air, relieving emotion, relieving anxiety and improving immunity by adding the frankincense and the myrrh.
3. The preparation method adopts microwaves and ultrasonic waves to treat the medicines during soaking, then adopts an autoclaving technology to sterilize, improves the preparation quality of the antibacterial liquid, improves the mixing uniformity of each component, promotes the contact of materials and microorganisms, improves the reaction rate and promotes mass transfer of the materials, can furthest reserve active ingredients in the antibacterial liquid medicine by placing the antibacterial liquid medicine in a high-pressure environment for sterilization, and effectively kills bacteria while ensuring the quality of the liquid medicine by the autoclaving technology, thereby improving the antibacterial effect of the antibacterial liquid medicine.
Detailed Description
The following description of the technical solution in the embodiments of the present invention is clear and complete.
The invention relates to a rheumatalgia antibacterial solution which comprises the following raw materials in parts by weight: 15-20 parts of ligusticum wallichii, 5-8 parts of stiff silkworm, 10-15 parts of asarum, 1-3 parts of ground beetle, 5-8 parts of prepared arisaema tuber, 3-5 parts of garden balsam stem, 3-5 parts of safflower, 5-8 parts of pseudo-ginseng, 3-5 parts of eucommia bark, 5-8 parts of astragalus root, 1-3 parts of frankincense, 1-3 parts of myrrh, 3-5 parts of scorpion, 3-5 parts of centipede, 3-5 parts of spatholobus stem, 1-3 parts of camphor, 1-3 parts of borneol, 1-3 parts of menthol and 1-3 parts of thymol.
The invention also provides a preparation method of the rheumatalgia antibacterial liquid, which is used for preparing the rheumatalgia antibacterial liquid and comprises the following steps:
s1: taking a proper amount of raw materials in parts by weight, respectively grinding the raw materials into powder, wherein the grinding granularity of each raw material is 400 meshes, and adding the raw materials into a reaction kettle;
s2: adding proper amount of alcohol and water into the reaction kettle, wherein the ratio of the alcohol to the water is set to 7:3, so that the medicinal materials are completely soaked, fully stirring and mixing by adopting a stirrer, ensuring that various components are uniformly distributed, and then soaking and fermenting for 15-20d;
s3: in the soaking process, a microwave heating component in a reaction kettle is started for heating the liquid medicine every day, the heating temperature of the microwave heating component is 55-60 ℃, then an ultrasonic generating component in the reaction kettle is started for carrying out ultrasonic treatment on the liquid medicine, the ultrasonic treatment time of the ultrasonic generating component is 8-10min, the ultrasonic can increase the mixing uniformity of materials, promote the contact of the materials with microorganisms, improve the reaction rate, promote mass transfer of the materials and the like in the fermentation process, the fluidity of the materials is changed by generating high-frequency vibration waves, the mixing degree is increased, tiny bubbles in the liquid are formed by generating cavitation phenomena, a larger contact interface is provided, and the reaction between the microorganisms and substrates is promoted;
s4: filtering out the medicinal materials after fermentation is completed, retaining the medicinal liquid, and carrying out ultrasonic treatment on the filtered clear medicinal liquid;
s5: the ultrasonic-treated clear liquid medicine is placed in a high-pressure environment for sterilization treatment, then the finished product is obtained by filling and packaging, the specification of the finished product is 50ml, the antibacterial liquid medicine is placed in the high-pressure environment for sterilization treatment, the active ingredients in the liquid medicine can be reserved to the maximum extent, and the high-pressure sterilization technology can effectively kill bacteria while guaranteeing the quality of the liquid medicine, so that the antibacterial effect of the antibacterial liquid medicine is improved.
The pharmacological effects of the components in the invention are as follows:
the rhizoma Ligustici Chuanxiong contains some active ingredients such as ligustilide and ligustilide, and has effects of dilating blood vessel, improving blood circulation, resisting oxidation, relieving inflammation, promoting blood circulation, improving symptoms of cardiovascular disease and cerebrovascular disease, and relieving pain.
The stiff silkworm contains abundant amino acids, has the function of a nerve transfer substance gamma-aminobutyric acid (GABA), can regulate the activity of a nervous system, plays a role in inhibiting excitation, effectively relieves the overexcited nervous system, and relieves symptoms such as spasm, convulsion and the like.
The main active component of the asarum is asarin, has irritation and volatility, can play roles in relieving fever, dispelling cold, dispelling wind and the like by stimulating respiratory tract, increasing blood circulation, dilating blood vessels and the like, and has pharmacological effects of easing pain, diminishing inflammation, resisting bacteria and the like.
On one hand, the ground beetle has an antibacterial effect, contains active ingredients such as flavonoid, alkaloid and the like, can effectively inhibit the growth of various bacteria and fungi, and has a certain effect on treating some infectious diseases; on the other hand, the composition has anti-inflammatory effect, can inhibit inflammatory reaction, reduce tissue inflammatory injury and promote repair of inflammation.
The prepared rhizoma arisaematis has the effects of balancing physical strength, enhancing immunity and improving disease resistance, is widely applied to the field of traditional Chinese medicines, has the effects of tonifying qi, strengthening spleen and the like, and can be used for treating symptoms such as weakness of spleen and stomach, deficiency of qi, weakness, inappetence and the like.
Herba speranskiae tuberculatae has effects of clearing heat, detoxicating, promoting blood circulation for removing blood stasis, promoting hair growth, etc.
Safflower has the effects of activating blood circulation to dissipate blood stasis, clearing heat and detoxicating, and the like, and is widely applied to the treatment of dysmenorrhea, abdominal pain, blood stasis, and the like.
Notoginseng radix contains various active ingredients such as saponin, notoginseng radix glycoside, etc., has various pharmacological effects, is commonly used as medicine for promoting blood circulation, relieving pain, detumescence and hemostasis, and can be widely used for treating various diseases such as heart disease, apoplexy, blood stasis, etc.
Eucommia ulmoides, eucommia ulmoides contains rich plant sterols and various amino acids, vitamins and the like required by human bodies, and has the effects of activating blood, resisting oxidation, resisting inflammation, enhancing kidney functions and the like.
Astragalus mongholicus and astragalus membranaceus are widely applied to the field of traditional Chinese medicines, are commonly used for enhancing immunity, improving physique, protecting health and the like, contain various nutritional ingredients such as flavonoids, amino acids, minerals and the like, and are used for treating symptoms such as fatigue and weakness, weakness and weakness, inappetence and weakness of spleen and stomach and the like.
The frankincense has various medicinal effects and fragrance characteristics, contains various active ingredients such as boswellic acid, lactitol and the like, is used for promoting blood circulation to remove blood stasis, resolving hard mass, relieving pain, dispelling wind, removing dampness and the like, is widely applied to treating symptoms such as arthritis, rheumatic arthritis, traumatic injury and the like, has the effects of easing pain, resisting bacteria, resisting inflammation, resisting oxidation and the like, gives off faint scent, and can refresh mind, purify air and relieve emotion.
The myrrh and myrrh have the main effects of stopping bleeding, diminishing inflammation, easing pain, resisting bacteria and the like, can be used for treating diseases such as canker sore, gingivitis, sore throat, gastrointestinal tract inflammation and the like, and the myrrh essential oil can also be used in aromatherapy, and has the effects of relieving emotion, relieving anxiety and improving immunity.
On one hand, the scorpion has analgesic effect, and contains various bioactive components such as scorpion toxin, scorpion extract and the like, and has remarkable analgesic effect; on one hand, the scorpion has an anti-inflammatory effect, has obvious anti-inflammatory activity, and can inhibit the occurrence and development of inflammatory reaction; on the one hand, the scorpion toxin has strong antibacterial activity, and can inhibit the growth and propagation of various bacteria.
One of the main components of centipede and centipede toxin is centipede activin which has antibacterial, antiviral and antitumor activities, can inhibit the growth of various bacteria and fungi, has obvious antiviral activity on various viruses and has cytoxic effect on various tumor cells.
Caulis Spatholobi and caulis Spatholobi have antiinflammatory, antibacterial, analgesic and blood circulation improving effects, and can inhibit inflammatory reaction, relieve inflammation symptoms, inhibit various bacteria, fungi and viruses, promote blood circulation, increase blood vessel elasticity, reduce thrombosis, relieve pain, and relieve various pains.
The camphor has local anesthetic effect, can relieve pain by blocking nerve conduction, has strong antibacterial capability, and can inhibit the growth of various bacteria and fungi.
Borneol and borneol can inhibit pain transmission by activating mu-opioid receptors of the central nervous system, thereby producing analgesic effect, and can be used for relieving acute and chronic pain, such as postoperative pain, cancer pain and the like.
Menthol can stimulate cold and hot receptors to generate cold feeling, thereby relieving pain, and can stimulate sensory nerve endings on skin to interfere transmission of pain signals, relieve discomfort such as headache, muscle pain and the like, inhibit inflammatory reaction and reduce release of inflammatory mediators, thereby having certain anti-inflammatory effect.
Thymol has certain antiinflammatory effect, can inhibit inflammatory mediator release and inflammatory reaction, has certain adjuvant therapeutic effect on inflammatory diseases such as rheumarthritis and inflammatory bowel disease, and has inhibiting effect on various bacteria and fungi, and can be used for treating some infectious diseases such as skin infection and respiratory tract infection.
Example 1
A rheumatalgia antibacterial solution comprises the following raw materials in parts by weight: 15 parts of ligusticum wallichii, 5 parts of stiff silkworm, 10 parts of asarum, 1 part of ground beetle, 5 parts of prepared rhizoma arisaematis, 3 parts of garden balsam stem, 3 parts of safflower, 5 parts of pseudo-ginseng, 3 parts of eucommia ulmoides, 5 parts of astragalus, 1 part of frankincense, 1 part of myrrh, 3 parts of scorpion, 3 parts of centipede, 3 parts of suberect spatholobus stem, 1 part of camphor, 1 part of borneol, 1 part of menthol and 1 part of thymol.
The antibacterial liquid is directly smeared on the parts of pain, swelling, numbness, sprain and contusion caused by closed soft tissue injury, such as cervical vertebra, perishoulder, lumbar vertebra, synovium, joint, heel, rheumatism, neck, shoulder, waist and leg and the like, 2-3 times a day, and 1 week is a treatment course.
Results: the pain parts of the patient are basically free from pain after one treatment course, a certain amount of pain can occur at the pain parts when the fingers of the individual patient are lightly pressed, and the pain parts of the patient are completely free from pain after two treatment courses, so that the patient can be completely recovered.
Example two
A rheumatalgia antibacterial solution comprises the following raw materials in parts by weight: 18 parts of ligusticum wallichii, 7 parts of stiff silkworm, 13 parts of asarum, 2 parts of ground beetle, 7 parts of prepared rhizoma arisaematis, 4 parts of garden balsam stem, 4 parts of safflower, 7 parts of pseudo-ginseng, 4 parts of eucommia ulmoides, 7 parts of astragalus membranaceus, 2 parts of frankincense, 2 parts of myrrh, 4 parts of scorpion, 4 parts of centipede, 4 parts of suberect spatholobus stem, 2 parts of camphor, 2 parts of borneol, 2 parts of menthol and 2 parts of thymol.
The antibacterial liquid is directly smeared on the parts of pain, swelling, numbness, sprain and contusion caused by closed soft tissue injury, such as cervical vertebra, perishoulder, lumbar vertebra, synovium, joint, heel, rheumatism, neck, shoulder, waist and leg and the like, 2-3 times a day, and 1 week is a treatment course.
Results: the pain parts of the patient are basically free from pain after one treatment course, a certain amount of pain can occur at the pain parts when the fingers of the individual patient are lightly pressed, and the pain parts of the patient are completely free from pain after two treatment courses, so that the patient can be completely recovered.
Example III
A rheumatalgia antibacterial solution comprises the following raw materials in parts by weight: 20 parts of ligusticum wallichii, 8 parts of stiff silkworm, 15 parts of asarum, 3 parts of ground beetle, 8 parts of prepared rhizoma arisaematis, 5 parts of garden balsam stem, 5 parts of safflower, 8 parts of pseudo-ginseng, 5 parts of eucommia ulmoides, 8 parts of astragalus, 3 parts of frankincense, 3 parts of myrrh, 5 parts of scorpion, 5 parts of centipede, 5 parts of suberect spatholobus stem, 3 parts of camphor, 3 parts of borneol, 3 parts of menthol and 3 parts of thymol.
The antibacterial liquid is directly smeared on the parts of pain, swelling, numbness, sprain and contusion caused by closed soft tissue injury, such as cervical vertebra, perishoulder, lumbar vertebra, synovium, joint, heel, rheumatism, neck, shoulder, waist and leg and the like, 2-3 times a day, and 1 week is a treatment course.
Results: the pain parts of the patient are basically free from pain after one treatment course, a certain amount of pain can occur at the pain parts when the fingers of the individual patient are lightly pressed, and the pain parts of the patient are completely free from pain after two treatment courses, so that the patient can be completely recovered.
The foregoing is only a preferred embodiment of the present invention, and the present invention is not limited thereto, and any modification, equivalent replacement, and improvement of some of the technical features described in the foregoing embodiments are all within the scope of the present invention.
Claims (8)
1. The rheumatalgia antibacterial solution is characterized by comprising the following raw materials in parts by weight:
15-20 parts of ligusticum wallichii, 5-8 parts of stiff silkworm, 10-15 parts of asarum, 1-3 parts of ground beetle, 5-8 parts of prepared arisaema tuber, 3-5 parts of garden balsam stem, 3-5 parts of safflower, 5-8 parts of pseudo-ginseng, 3-5 parts of eucommia bark, 5-8 parts of astragalus root, 1-3 parts of frankincense, 1-3 parts of myrrh, 3-5 parts of scorpion, 3-5 parts of centipede, 3-5 parts of spatholobus stem, 1-3 parts of camphor, 1-3 parts of borneol, 1-3 parts of menthol and 1-3 parts of thymol.
2. The rheumatalgia antibacterial solution according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 15 parts of ligusticum wallichii, 5 parts of stiff silkworm, 10 parts of asarum, 1 part of ground beetle, 5 parts of prepared rhizoma arisaematis, 3 parts of garden balsam stem, 3 parts of safflower, 5 parts of pseudo-ginseng, 3 parts of eucommia ulmoides, 5 parts of astragalus, 1 part of frankincense, 1 part of myrrh, 3 parts of scorpion, 3 parts of centipede, 3 parts of suberect spatholobus stem, 1 part of camphor, 1 part of borneol, 1 part of menthol and 1 part of thymol.
3. The rheumatalgia antibacterial solution according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 18 parts of ligusticum wallichii, 7 parts of stiff silkworm, 13 parts of asarum, 2 parts of ground beetle, 7 parts of prepared rhizoma arisaematis, 4 parts of garden balsam stem, 4 parts of safflower, 7 parts of pseudo-ginseng, 4 parts of eucommia ulmoides, 7 parts of astragalus membranaceus, 2 parts of frankincense, 2 parts of myrrh, 4 parts of scorpion, 4 parts of centipede, 4 parts of suberect spatholobus stem, 2 parts of camphor, 2 parts of borneol, 2 parts of menthol and 2 parts of thymol.
4. The rheumatalgia antibacterial solution according to claim 1, which is characterized by comprising the following raw materials in parts by weight: 20 parts of ligusticum wallichii, 8 parts of stiff silkworm, 15 parts of asarum, 3 parts of ground beetle, 8 parts of prepared rhizoma arisaematis, 5 parts of garden balsam stem, 5 parts of safflower, 8 parts of pseudo-ginseng, 5 parts of eucommia ulmoides, 8 parts of astragalus, 3 parts of frankincense, 3 parts of myrrh, 5 parts of scorpion, 5 parts of centipede, 5 parts of suberect spatholobus stem, 3 parts of camphor, 3 parts of borneol, 3 parts of menthol and 3 parts of thymol.
5. A method for preparing a rheumatalgia antibacterial solution, which is used for preparing the rheumatalgia antibacterial solution according to any one of claims 1-4, and is characterized by comprising the following steps:
s1: taking a proper amount of raw materials in parts by weight, respectively grinding the raw materials into powder, and adding the powder into a reaction kettle;
s2: adding proper amount of alcohol and water into a reaction kettle to completely soak the medicinal materials, fully stirring and mixing by adopting a stirrer to ensure that various components are uniformly distributed, and then soaking and fermenting for 15-20d;
s3: in the soaking process, a microwave heating assembly in the reaction kettle is started every day to heat the liquid medicine, and then an ultrasonic generating assembly in the reaction kettle is started to carry out ultrasonic treatment on the liquid medicine;
s4: filtering out the medicinal materials after fermentation is completed, retaining the medicinal liquid, and carrying out ultrasonic treatment on the filtered clear medicinal liquid;
s5: and (3) placing the ultrasonic-treated clear liquid medicine in a high-pressure environment for sterilization treatment, and then filling and packaging to obtain a finished product.
6. The method for preparing a rheumatalgia-relieving antibacterial solution according to claim 5, wherein the grinding particle size of each raw material in the step S1 is 400 meshes.
7. The method for preparing a rheumatalgia-relieving and antibacterial solution according to claim 5, wherein the ratio of alcohol to water in the S2 is set to 7:3.
8. The method for preparing a rheumatalgia-relieving antibacterial solution according to claim 5, wherein the heating temperature of the microwave heating assembly in step S3 is 55-60 ℃, and the ultrasonic treatment time of the ultrasonic generating assembly is 8-10min.
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| CN102618440A (en) * | 2011-01-31 | 2012-08-01 | 中国科学院过程工程研究所 | Ultrasound-enhanced bioreactor |
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| CN114452367A (en) * | 2022-01-24 | 2022-05-10 | 陈丽波 | Bacteriostatic wiping solution for pain of rheumatoid bone disease |
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| CN102618440A (en) * | 2011-01-31 | 2012-08-01 | 中国科学院过程工程研究所 | Ultrasound-enhanced bioreactor |
| CN103316308A (en) * | 2012-03-20 | 2013-09-25 | 于文波 | Traditional Chinese medical liquor for external use |
| CN114452367A (en) * | 2022-01-24 | 2022-05-10 | 陈丽波 | Bacteriostatic wiping solution for pain of rheumatoid bone disease |
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