CN116731854A - Production equipment and production method of astragalus peptide - Google Patents
Production equipment and production method of astragalus peptide Download PDFInfo
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- CN116731854A CN116731854A CN202310698555.7A CN202310698555A CN116731854A CN 116731854 A CN116731854 A CN 116731854A CN 202310698555 A CN202310698555 A CN 202310698555A CN 116731854 A CN116731854 A CN 116731854A
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- 235000006533 astragalus Nutrition 0.000 title claims abstract description 41
- 241001061264 Astragalus Species 0.000 title claims abstract description 38
- 210000004233 talus Anatomy 0.000 title claims abstract description 38
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 37
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 34
- 239000007788 liquid Substances 0.000 claims abstract description 151
- 238000006243 chemical reaction Methods 0.000 claims abstract description 73
- 238000002156 mixing Methods 0.000 claims abstract description 40
- 230000007246 mechanism Effects 0.000 claims abstract description 30
- 239000000203 mixture Substances 0.000 claims abstract description 9
- 238000003756 stirring Methods 0.000 claims description 52
- 238000007599 discharging Methods 0.000 claims description 28
- 238000005507 spraying Methods 0.000 claims description 20
- 235000019206 astragalus extract Nutrition 0.000 claims description 19
- 230000005540 biological transmission Effects 0.000 claims description 8
- 108010011619 6-Phytase Proteins 0.000 claims description 6
- 108091005804 Peptidases Proteins 0.000 claims description 6
- 239000004365 Protease Substances 0.000 claims description 6
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims description 6
- 241001409321 Siraitia grosvenorii Species 0.000 claims description 6
- 235000011171 Thladiantha grosvenorii Nutrition 0.000 claims description 6
- 229940085127 phytase Drugs 0.000 claims description 6
- 239000011259 mixed solution Substances 0.000 claims description 5
- 239000000243 solution Substances 0.000 claims description 5
- 230000003301 hydrolyzing effect Effects 0.000 claims description 4
- 238000009826 distribution Methods 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 210000003781 tooth socket Anatomy 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 abstract description 13
- 108090000790 Enzymes Proteins 0.000 abstract description 13
- 230000000694 effects Effects 0.000 abstract description 13
- 238000002360 preparation method Methods 0.000 abstract description 6
- 229940047169 astragalus root extract Drugs 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 description 20
- 230000008569 process Effects 0.000 description 16
- 229940088598 enzyme Drugs 0.000 description 12
- 230000009471 action Effects 0.000 description 5
- 230000001976 improved effect Effects 0.000 description 4
- 241000045403 Astragalus propinquus Species 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 229940107666 astragalus root Drugs 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 208000006820 Arthralgia Diseases 0.000 description 1
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000001133 acceleration Effects 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000009849 deactivation Effects 0.000 description 1
- 230000000593 degrading effect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
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- 238000005516 engineering process Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
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- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
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- 208000030159 metabolic disease Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/18—Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/18—Flow directing inserts
- C12M27/20—Baffles; Ribs; Ribbons; Auger vanes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/18—Flow directing inserts
- C12M27/22—Perforated plates, discs or walls
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/10—Process efficiency
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Abstract
The invention discloses production equipment and a production method of astragalus peptide, which belong to the technical field of astragalus peptide preparation and comprise a reaction tank for astragalus peptide preparation enzymolysis, a liquid inlet pipe arranged at the top of the reaction tank and a liquid outlet pipe arranged at the bottom of the reaction tank, wherein a rotating shaft is rotatably arranged in the reaction tank, and a primary mixing mechanism is arranged outside the rotating shaft. Through last spiral leaf and lower spiral leaf simultaneously rotate with the mixed liquor to the middle part of retort carry and get into the annular cover in for two strands of mixed liquor can strike and mix each other alternately, make the mixed liquor of being sent into can carry out fine mixing in the annular cover, and mixed liquor after mixing sprays out to the retort through a plurality of irregularly setting at the hydrojet mouth on flowing back box surface irregularly, thereby make from the annular cover in the discharged mixed liquor can more fully be sprayed and dispersed to the retort, make the mixing effect between astragalus root extract and the enzymolysis enzyme better, and mixing efficiency is higher.
Description
Technical Field
The invention relates to the technical field of astragalus peptide preparation, in particular to production equipment and a production method of astragalus peptide.
Background
Astragalus membranaceus is the dry root of Astragalus mongholicus bge or Astragalus membranaceus bge. The Chinese medicinal composition is originally loaded in Shennong's herbal channels, and has the effects of tonifying qi and yang, strengthening exterior and arresting sweating, inducing diuresis and detumescence, promoting fluid production and nourishing blood, promoting stagnancy and relieving arthralgia, expelling toxin and pus, healing sore and promoting granulation. Modern medicine researches have the effects of resisting tumor, atherosclerosis, virus and injury, reducing blood sugar and treating metabolic disorder. The astragalus peptide is a small molecular peptide prepared from astragalus serving as a raw material, and has the effects of reducing blood pressure, reducing blood fat and the like.
During the production and preparation process of the astragalus peptide, a series of complicated procedures are required to be carried out: the raw materials are dried, crushed, fed, pulped, subjected to enzymolysis, enzyme deactivation, separation, filtration and the like, and the enzymolysis process is taken as a process of degrading protein to form amino acid, and the enzymolysis effect determines the quality of astragalus extract and the quality of subsequently obtained astragalus peptide, so that the enzymolysis process is an extremely important link in the preparation process of the astragalus peptide. In the process of enzymolysis of the astragalus extract, the distribution condition of the added enzymolysis enzyme determines the enzymolysis degree of the astragalus extract, so that after the enzymolysis enzyme is added into the reaction tank, the enzymolysis enzyme and the astragalus extract are stirred by using a stirring mechanism. The stirring structure that sets up in the current retort is mostly flat stirring board, is stirring the in-process, and the high mixed solution of different positions mixes the range of variation less, consequently in stirring the in-process, need spend more time and be used for enzymolysis enzyme and extract's mixture, not only make the astragalus peptide preparation inefficiency, still make enzymolysis enzyme's mixed effect not enough simultaneously, make it unable to carry out more abundant and efficient enzymolysis to the astragalus extract in the retort.
Disclosure of Invention
The invention aims to provide production equipment and a production method of astragalus peptide, which are used for solving the problems in the background technology.
In order to achieve the above purpose, the present invention provides the following technical solutions: the production equipment of the astragalus peptide comprises a reaction tank for preparing and enzymolysis of the astragalus peptide, a liquid inlet pipe arranged at the top of the reaction tank and a liquid outlet pipe arranged at the bottom of the reaction tank, wherein a rotating shaft is rotatably arranged in the reaction tank, and a primary mixing mechanism is arranged outside the rotating shaft;
the primary mixing mechanism comprises a first spiral blade and a second spiral blade which are symmetrically arranged outside a rotating shaft, the rotation directions of the first spiral blade and the second spiral blade are opposite, a plurality of connecting rods are arranged outside the rotating shaft, the outer parts of the connecting rods are fixedly connected with an annular cover, a plurality of liquid discharge grooves are formed in the surface of the annular cover, a plurality of liquid discharge boxes corresponding to the liquid discharge grooves are arranged on the surface of the annular cover, and a liquid spraying port is formed in the surface of the liquid discharge box;
when the rotating shaft rotates, the first spiral blade and the second spiral blade synchronously rotate, and the mixed liquid at the upper end and the bottom end inside the reaction tank flows into the annular cover and collides with each other.
As still further aspects of the invention: the annular cover is arranged at the middle position inside the reaction tank, the caliber values of the openings at the upper end and the lower end of the annular cover are both larger than the maximum outer diameter values of the first spiral blade and the second spiral blade, and one end of the first spiral blade, which is close to the annular cover, and one end of the second spiral blade, which is close to the annular cover, are all extended to the inside of the annular cover, so that the mixed liquid can be fed into the annular cover more stably when the first spiral blade and the second spiral blade rotate to convey the mixed liquid in the reaction tank, and meanwhile, the initial speed of the mixed liquid entering the annular cover is relatively high, and the mixed liquid flowing in opposite directions can be subjected to convection impact and mixing better.
As still further aspects of the invention: the liquid discharge grooves are distributed on the surface of the annular cover at equal angles, the positions and the dimension specifications of the liquid discharge boxes are corresponding to those of the liquid discharge grooves, and the liquid discharge boxes are communicated with the liquid discharge grooves, so that mixed liquid in the annular cover can be discharged.
As still further aspects of the invention: the liquid spraying ports located on the liquid discharging boxes are irregularly distributed on the surfaces of the liquid discharging boxes, the size values of the liquid spraying ports are irregularly arranged, so that mixed liquid flowing into the liquid discharging boxes from the annular cover can be sprayed into the reaction tank from the liquid spraying ports on the liquid discharging boxes in different directions when being discharged, and the sprayed flow is different, and therefore the mixed liquid after being mixed once in the annular cover can be sprayed into all directions in the reaction tank again in a diffusion mode, and enzymolysis enzyme can be mixed with astragalus root extracting liquid better.
As still further aspects of the invention: the reaction tank is characterized in that a secondary mixing mechanism is further arranged in the reaction tank and comprises connecting plates which are distributed outside the rotating shaft from top to bottom, the two connecting plates are fixedly connected with the rotating shaft, a rotating rod is connected between the two connecting plates in a rotating mode, a plurality of first stirring plates and a plurality of second stirring plates are sequentially arranged on the surface of the rotating rod, and a transmission assembly is arranged outside the connecting plates.
As still further aspects of the invention: the transmission assembly comprises a gear rotationally connected to the surface of the connecting plate, and a plurality of tooth grooves are formed in the inner side surface of the reaction tank; the gear is coaxial fixed connection with the dwang, a plurality of tooth's socket is annular equidistant distribution at the medial surface of retort, just gear and tooth's socket meshing, when the pivot rotated, the connecting plate was used the pivot to rotate as the circumference of rotation axis, the gear was synchronous to be used the dwang to rotate as the circumference of rotation axis for the gear when using the dwang to rotate as the rotation axis to carry out circumference, still can use the pivot to rotate as the rotation axis, thereby can more fully carry out the mixed treatment to the inside mixed solution of retort.
As still further aspects of the invention: the secondary mixing mechanism further comprises a first guide plate arranged on the surface of the first stirring plate, a second guide plate is arranged on the surface of the second stirring plate, and the surfaces of the first guide plate and the second guide plate are obliquely arranged.
As still further aspects of the invention: the surface inclination directions of the first guide plate and the second guide plate are opposite, and the surface inclination angles of the first guide plate and the second guide plate are 75 degrees, so that mixed liquid flowing to the first stirring plate and the second stirring plate under the matching action of the annular cover, the liquid discharging box and the liquid spraying port can be respectively conveyed upwards and downwards under the guiding action of the first guide plate and the second guide plate, the mixed liquid positioned outside the annular cover can continuously flow up and down in a staggered manner and continuously collide and mix in the process, the final mixing effect is better, and the mixing efficiency is higher.
The production method of the astragalus peptide is applied to the production equipment of the astragalus peptide and comprises the following steps:
s1, feeding astragalus extract to be subjected to enzymolysis into a reaction tank;
s2, adding momordica grosvenori protease and phytase for enzymolysis reaction into a reaction tank after adding the astragalus extract;
s3, heating the interior of a reaction tank, in which astragalus extract, momordica grosvenori protease and phytase are added, to 55-58 ℃, and then stirring and enzymolysis are carried out on the mixed solution in the reaction tank for 2-3 hours;
s4, performing enzymolysis reaction;
s5, discharging the extracting solution obtained after enzymolysis.
Compared with the prior art, the invention has the beneficial effects that:
1. according to the production equipment and the production method of the astragalus peptide, the upper spiral blade and the lower spiral blade rotate simultaneously, the mixed liquid positioned at the top and the bottom of the reaction tank is conveyed to the middle of the reaction tank at the same time, the conveyed mixed liquid is conveyed into the annular cover at a certain acceleration, finally, the conveyed mixed liquid contacts in the annular cover and collides, the two liquid after collision are mixed with each other in a staggered mode, the mixed liquid at the rear continuously impacts the mixed liquid at the front, the mixed liquid can be well mixed in the annular cover, the mixed liquid after mixing is irregularly sprayed out of the reaction tank through the liquid spraying holes irregularly arranged on the surface of the liquid discharging box, in the process, the liquid discharging box keeps a rotating state, and therefore the mixed liquid discharged from the annular cover can be more fully sprayed and dispersed into the reaction tank, the mixing effect between the astragalus extracting liquid and the enzymolysis enzyme is better, and the mixing efficiency is higher.
2. According to the production equipment and the production method of the astragalus peptide, through the cooperation transmission of the gears and the tooth grooves, the first stirring plate and the second stirring plate can rotate around the rotating shaft and also rotate around the rotating rod, in addition, in the rotating process of the first stirring plate and the second stirring plate, the mixed liquid conveyed to the rotating rod direction can be sequentially conveyed in the direction of obliquely upwards and downwards in a staggered manner, in the conveying process, the mixed liquid sprayed out of the liquid spraying opening can be impacted and mixed, so that the mixing effect of the mixed liquid in the reaction tank can be further improved, the mixing efficiency is higher, enzymolysis enzymes and astragalus extract can be more fully mixed and contacted, and the enzymolysis efficiency of the astragalus extract can be further improved.
Drawings
FIG. 1 is a schematic perspective view of the present invention;
FIG. 2 is a schematic diagram of a cross-sectional structure of a reaction tank according to the present invention;
FIG. 3 is an enlarged schematic view of the structure of FIG. 2A according to the present invention;
FIG. 4 is a schematic diagram of the internal structure of the reaction tank of the present invention;
FIG. 5 is a schematic perspective view of a primary mixing mechanism according to the present invention;
FIG. 6 is an enlarged schematic view of the structure of FIG. 5B according to the present invention;
FIG. 7 is an enlarged schematic view of the structure of FIG. 5C according to the present invention;
fig. 8 is a schematic structural view showing the connection states of the first stirring plate, the second stirring plate, the first guide plate and the second guide plate according to the present invention.
The correspondence between the reference numerals and the component names in the drawings is as follows:
1. a reaction tank; 2. a liquid inlet pipe; 3. a liquid discharge pipe; 4. a rotating shaft; 5. a primary mixing mechanism; 51. a first helical leaf; 52. a connecting rod; 53. a liquid discharge tank; 54. a second helical leaf; 55. a liquid discharge box; 56. a liquid spraying port; 57. an annular cover; 6. a secondary mixing mechanism; 61. a connecting plate; 62. a rotating lever; 63. a first stirring plate; 64. a second stirring plate; 65. a transmission assembly; 651. a gear; 652. tooth slots; 66. a first guide plate; 67. and a second guide plate.
Detailed Description
Please refer to fig. 1-7: the production equipment of the astragalus peptide comprises a reaction tank 1 for preparing and hydrolyzing the astragalus peptide, a liquid inlet pipe 2 arranged at the top of the reaction tank 1, a liquid outlet pipe 3 arranged at the bottom of the reaction tank 1, a drying mechanism, a crushing mechanism, a feeding mechanism, a pulp mixing mechanism, an enzymolysis mechanism, a separating mechanism, a filtering mechanism and the like, wherein the enzymolysis mechanism comprises the reaction tank 1, the mechanisms are all components in the production equipment of the astragalus peptide and are all existing mechanisms in the existing equipment, the existing mechanisms are not repeated in the prior art, a rotating shaft 4 is arranged in the reaction tank 1 in a rotating way, a motor is arranged outside the reaction tank 1, the rotating shaft 4 is fixedly connected with an output shaft of the motor in a coaxial way, and a primary mixing mechanism 5 is arranged outside the rotating shaft 4;
the primary mixing mechanism 5 comprises a first spiral blade 51 and a second spiral blade 54 which are symmetrically arranged outside the rotating shaft 4, the rotation directions of the first spiral blade 51 and the second spiral blade 54 are opposite, a plurality of connecting rods 52 are arranged outside the rotating shaft 4, an annular cover 57 is fixedly connected to the outer parts of the connecting rods 52, a plurality of liquid discharge grooves 53 are formed in the surface of the annular cover 57, a plurality of liquid discharge boxes 55 corresponding to the liquid discharge grooves 53 are arranged on the surface of the annular cover 57, and a liquid spraying port 56 is formed in the surface of the liquid discharge box 55;
when the rotating shaft 4 rotates, the first spiral blade 51 and the second spiral blade 54 rotate synchronously, and the rotation directions of the first spiral blade 51 and the second spiral blade 54 are opposite, so that the first spiral blade 51 rotates to convey the mixed liquid above downwards, the second spiral blade 54 synchronously rotates to convey the mixed liquid below in the reaction tank 1 upwards, simultaneously, two mixed liquids moving up and down respectively enter the annular cover 57 and contact and collide with the inside of the annular cover 57, the two mixed liquids during collision are alternately and alternately mixed, and under the action of the impact force, the two mixed liquids after collision diffuse to the periphery in the annular cover 57 and collide and return to the inner wall of the annular cover 57, so that the mixed liquid inside the annular cover 57 can be mixed with better effect.
In this embodiment, the annular cover 57 is disposed at a middle position inside the reaction tank 1, the caliber values of the openings at the upper and lower ends of the annular cover 57 are both greater than the maximum outer diameter values of the first spiral vane 51 and the second spiral vane 54, and one end of the first spiral vane 51 close to the annular cover 57 and one end of the second spiral vane 54 close to the annular cover 57 are both extended to the inside of the annular cover 57, so that the first spiral vane 51 and the second spiral vane 54 can more stably convey the mixed liquid into the annular cover 57 when rotating to convey the mixed liquid in the reaction tank 1, and meanwhile, the initial speed of the mixed liquid entering the annular cover 57 is relatively high, so that the mixed liquid flowing in opposite directions can better perform convection impact and mix.
The liquid discharging grooves 53 are equiangularly distributed on the surface of the annular cover 57, the positions and the dimension specifications of the liquid discharging boxes 55 correspond to those of the liquid discharging grooves 53, the liquid discharging boxes 55 are communicated with the liquid discharging grooves 53, and therefore when the continuous rotation of the first spiral blades 51 and the second spiral blades 54 fully causes the liquid mixing in the annular cover 57 to be conveyed, the liquid mixing liquid flows into the liquid discharging boxes 55 through the liquid discharging grooves 53, finally flows out of the annular cover 57 through the liquid discharging grooves 53 formed on the surface of the liquid discharging boxes 55, and is mixed with part of the liquid mixing liquid located outside the annular cover 57 in the reaction tank 1.
In this embodiment, the liquid spraying ports 56 of the liquid discharging boxes 55 are randomly distributed on the surfaces of the liquid discharging boxes 55, and the size values of the liquid spraying ports 56 are randomly arranged, so that when the mixed liquid flowing into the liquid discharging boxes 55 from the annular cover 57 is discharged, the sprayed mixed liquid can be sprayed into the reaction tank 1 from the liquid spraying ports 56 on the liquid discharging boxes 55 in different directions, and the sprayed flow is different, so that the mixed liquid after once mixing in the annular cover 57 can be sprayed into the reaction tank 1 again, and the annular cover 57 can drive the liquid discharging boxes 55 to rotate circumferentially with the rotating shaft 4 as a rotating shaft in the rotating process, so that the mixed liquid can be sprayed into the reaction tank 1 along with the rotation of the liquid discharging boxes 55 and the liquid spraying ports 56 when discharged from the liquid discharging boxes 55, and the sprayed mixed liquid can be sprayed into the reaction tank 1 more in a dispersed manner, and the enzymolysis enzyme can be mixed with the astragalus root extracting liquid better.
Referring to fig. 2-4 and 8, in the embodiment, a secondary mixing mechanism 6 is further disposed inside the reaction tank 1, the secondary mixing mechanism 6 includes a connecting plate 61 vertically distributed outside the rotating shaft 4, two connecting plates 61 are fixedly connected with the rotating shaft 4, a rotating rod 62 is rotatably connected between the two connecting plates 61, a plurality of first stirring plates 63 and a plurality of second stirring plates 64 are sequentially disposed on the surface of the rotating rod 62, and a transmission assembly 65 is disposed outside the connecting plates 61.
In this embodiment, the transmission assembly 65 includes a gear 651 rotatably connected to the surface of the connection plate 61, and a plurality of tooth grooves 652 are formed on the inner side surface of the reaction tank 1; the gear 651 is fixedly connected with the rotating rod 62 coaxially, the tooth grooves 652 are annularly and equidistantly distributed on the inner side surface of the reaction tank 1, the gear 651 is meshed with the tooth grooves 652, when the rotating shaft 4 rotates, the connecting plate 61 rotates circumferentially by taking the rotating shaft 4 as a rotating shaft, the gear 651 synchronously rotates circumferentially by taking the rotating rod 62 as the rotating shaft, the gear 651 can also rotate circumferentially by taking the rotating shaft 4 as the rotating shaft while rotating circumferentially by taking the rotating rod 62 as the rotating shaft, and therefore mixed liquid in the reaction tank 1 can be fully mixed.
In this embodiment, the secondary mixing mechanism 6 further includes a first guide plate 66 provided on the surface of the first stirring plate 63, a second guide plate 67 is provided on the surface of the second stirring plate 64, the surfaces of the first guide plate 66 and the second guide plate 67 are each inclined, the inclined directions of the surfaces of the first guide plate 66 and the second guide plate 67 are opposite, and the inclined surfaces of the first guide plate 66 and the second guide plate 67 are each inclined upward and downward, respectively, and the inclined angles of the surfaces of the two and first guide plates 66 and the second guide plate 67 are both 75 °, so that when the connection plate 61 performs circumferential rotation about the rotation shaft 4, the gear 651 performs circumferential rotation about the rotation shaft 4 in synchronization, and also performs circumferential rotation about the rotation shaft 62, the gear 651 drives the rotating rod 62 and the first stirring plate 63 and the second stirring plate 64 arranged on the rotating rod 62 to synchronously rotate when the rotating rod 62 is used as a rotating shaft, and drives the first guide plate 66 and the second guide plate 67 arranged on the surfaces of the first stirring plate 63 and the second stirring plate 64 to rotate when the rotating rod 62 is used as a rotating shaft, and the surfaces of the first guide plate 66 and the second guide plate 67 are obliquely arranged and are respectively and obliquely arranged upwards and downwards in opposite oblique directions, so that in the rotating process, the first guide plate 66 and the second guide plate 67 can be pushed to be close to the first stirring plate 63 and the second stirring plate 64 to be sequentially and alternately conveyed upwards and downwards, and when the mixed liquid flows in an up-down staggered manner, the mixed liquid in the rear direction is relatively fast in conveying speed, the mixed liquid in the rear direction is alternately and alternately impacted with the mixed liquid in the front direction, and, the first stirring plate 63 and the second stirring plate 64 perform circumferential rotation with the rotating shaft 4 as the rotating shaft while performing circumferential rotation with the rotating rod 62 as the rotating shaft, so that the first stirring plate 63 and the second stirring plate 64 can be matched to sufficiently mix the mixed liquid in the reaction tank 1.
The production method of the astragalus peptide, which adopts the production equipment of the astragalus peptide, comprises the following steps:
s1, feeding astragalus extract to be subjected to enzymolysis into a reaction tank 1;
s2, adding momordica grosvenori protease and phytase for enzymolysis reaction into a reaction tank 1 after adding the astragalus extract;
s3, heating the interior of the reaction tank 1, which is added with the astragalus extract, the momordica grosvenori protease and the phytase, to 55-58 ℃, and then stirring and hydrolyzing the mixed solution in the reaction tank for 2-3 hours;
s4, performing enzymolysis reaction;
s5, discharging the extracting solution obtained after enzymolysis.
Working principle: when the mixed liquid in the reaction tank 1 is mixed and stirred, the first spiral blade 51 and the second spiral blade 54 are driven to rotate synchronously through the rotation of the rotating shaft 4, and as the rotation directions of the first spiral blade 51 and the second spiral blade 54 are opposite, the first spiral blade 51 conveys the mixed liquid above downwards through rotation, the second spiral blade 54 synchronously rotates and conveys the mixed liquid below the reaction tank 1 upwards, simultaneously two mixed liquids moving upwards and downwards respectively enter the annular cover 57 and contact and collide with the inside of the annular cover 57, the two mixed liquids in the collision process are alternately and alternately mixed, the two mixed liquids after the collision spread all around in the annular cover 57 under the action of the impact force and collide and bounce around the inner wall of the annular cover 57, the mixed liquid in the annular cover 57 can be mixed better, at this time, under the transmission action of the connecting rod 52, the annular cover 57 can synchronously rotate along with the rotating shaft 4, and along with the continuous rotation of the first spiral blade 51 and the second spiral blade 54, the mixed liquid pressure entering the annular cover 57 is increased, so that the mixed liquid in the annular cover can enter the liquid discharge box 55 from a plurality of liquid discharge grooves 53 arranged on the surface of the annular cover, and finally be sprayed from liquid spraying ports 56 on the liquid discharge box 55, because the liquid spraying ports 56 on the liquid discharge box 55 are randomly arranged and have different sizes, the mixed liquid sprayed from the liquid spraying ports 56 can be sprayed into the mixed liquid outside the annular cover 57 in different directions, and in the process, the rotation of the annular cover 57 can drive the liquid discharge box 55 to rotate, and in the process of the rotation of the liquid discharge box 55, the liquid spraying ports 56 can be driven to rotate, so that the mixed liquid sprayed from the plurality of liquid discharge boxes 55 can be more sufficiently dispersed into the mixed liquid outside the annular cover 57, so that the mixing efficiency of the mixed liquid is higher and the mixing effect is better;
the rotating shaft 4 can drive the connecting plate 61 to rotate circumferentially by taking the rotating shaft 4 as a rotating shaft in the rotating process, the connecting plate 61 drives the gear 651 to rotate circumferentially by taking the rotating shaft 4 as a rotating shaft in the rotating process, under the meshing effect of the tooth grooves 652, the gear 651 can rotate circumferentially by taking the rotating shaft 4 as a rotating shaft and simultaneously rotate by taking the rotating rod 62 as a rotating shaft, the gear 651 can drive the rotating rod 62 and the first stirring plate 63 and the second stirring plate 64 arranged on the rotating rod 62 to synchronously rotate when rotating circumferentially by taking the rotating rod 62 as the rotating shaft, the first stirring plate 63 and the second stirring plate 64 can also drive the first guide plate 66 and the second guide plate 67 arranged on the surfaces of the first stirring plate and the second stirring plate 63 to rotate when rotating circumferentially by taking the rotating rod 62 as the rotating shaft, and the surfaces of the first guide plate 66 and the second guide plate 67 are all obliquely arranged, and the inclined directions are opposite, and the first guide plate 66 and the second guide plate 67 are respectively arranged in an upward inclined manner and a downward inclined manner, so that in the rotating process, the mixture which is pushed to be close to the first stirring plate 63 and the second stirring plate 64 can be sequentially and alternately conveyed upward and downward, when the mixed liquid flows in an upward and downward staggered manner, the conveying speed of the mixed liquid at the rear part is higher, the mixed liquid which is alternately arranged at the front part can be alternately impacted, in addition, the first stirring plate 63 and the second stirring plate 64 can also perform circumferential rotation with the rotating shaft 4 as the rotating shaft when the rotating rod 62 is used as the rotating shaft, so that the first stirring plate 63 and the second stirring plate 64 can be matched to sufficiently mix the mixed liquid in the reaction tank 1, and the mixing effect and the mixing efficiency between the astragalus extract and the enzymolysis enzyme can be further improved, the method is favorable for more fully mixing and contacting the enzymolysis enzyme and the astragalus extract, so that the enzymolysis efficiency of the astragalus extract is further improved.
The foregoing description is only a preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art, who is within the scope of the present invention, should make equivalent substitutions or modifications according to the technical solution of the present invention and the inventive concept thereof, and should be covered by the scope of the present invention.
Claims (10)
1. The production equipment of the astragalus peptide comprises a reaction tank (1) for preparing and hydrolyzing the astragalus peptide, a liquid inlet pipe (2) arranged at the top of the reaction tank (1) and a liquid outlet pipe (3) arranged at the bottom of the reaction tank (1), and is characterized in that a rotating shaft (4) is rotatably arranged in the reaction tank (1), and a primary mixing mechanism (5) is arranged outside the rotating shaft (4);
the primary mixing mechanism (5) comprises a first spiral blade (51) and a second spiral blade (54) which are symmetrically arranged outside a rotating shaft (4), the rotation directions of the first spiral blade (51) and the second spiral blade (54) are opposite, a plurality of connecting rods (52) are arranged outside the rotating shaft (4), a plurality of annular covers (57) are fixedly connected to the outer parts of the connecting rods (52), a plurality of liquid discharge grooves (53) are formed in the surfaces of the annular covers (57), a plurality of liquid discharge boxes (55) corresponding to the liquid discharge grooves (53) are arranged on the surfaces of the annular covers (57), and liquid spraying openings (56) are formed in the surfaces of the liquid discharge boxes (55);
when the rotating shaft (4) rotates, the first spiral blade (51) and the second spiral blade (54) synchronously rotate, and the mixture liquid at the upper end and the bottom end in the reaction tank (1) flows into the annular cover (57) in a phase-wise manner and collides with each other.
2. The production facility of astragalus peptide according to claim 1, wherein the annular cover (57) is provided at a central position inside the reaction tank (1), the aperture values of the openings at the upper and lower ends of the annular cover (57) are both larger than the maximum outer diameter values of the first spiral blade (51) and the second spiral blade (54), and one end of the first spiral blade (51) close to the annular cover (57) and one end of the second spiral blade (54) close to the annular cover (57) are both extended to the inside of the annular cover (57).
3. The production facility of astragalus peptides according to claim 1, wherein a plurality of said drain grooves (53) are equiangularly distributed on the surface of the annular cover (57), and wherein the drain boxes (55) are located and dimensioned to correspond to the drain grooves (53), and wherein the drain boxes (55) are in communication with the drain grooves (53).
4. The production facility of Astragalus peptide as claimed in claim 3, wherein the liquid spraying ports (56) located in the plurality of liquid discharging boxes (55) are irregularly distributed on the surfaces of the plurality of liquid discharging boxes (55), and the size values of the plurality of liquid spraying ports (56) are irregularly arranged.
5. The production facility of astragalus peptide according to claim 1, wherein the inside of retort (1) still is provided with second grade mixing mechanism (6), second grade mixing mechanism (6) are including upper and lower distribution at the outside connecting plate (61) of pivot (4), two connecting plate (61) all with pivot (4) fixed connection, two rotate between connecting plate (61) and be connected with dwang (62), the surface of dwang (62) has set gradually a plurality of first stirring board (63) and a plurality of second stirring board (64), the outside of connecting plate (61) is provided with drive assembly (65).
6. The production equipment of astragalus peptide according to claim 5, wherein the transmission assembly (65) comprises a gear (651) rotatably connected to the surface of the connecting plate (61), and a plurality of tooth sockets (652) are formed on the inner side surface of the reaction tank (1).
7. The production facility of astragalus peptide according to claim 6, wherein the gear (651) is fixedly connected with the rotating rod (62) coaxially, a plurality of tooth grooves (652) are distributed on the inner side surface of the reaction tank (1) in a ring shape at equal intervals, the gear (651) is meshed with the tooth grooves (652), when the rotating shaft (4) rotates, the connecting plate (61) performs circumferential rotation by taking the rotating shaft (4) as a rotating shaft, and the gear (651) performs circumferential rotation by taking the rotating rod (62) as a rotating shaft synchronously.
8. The production facility of astragalus peptides according to claim 7, wherein the secondary mixing mechanism (6) further comprises a first guiding plate (66) arranged on the surface of the first stirring plate (63), the surface of the second stirring plate (64) is provided with a second guiding plate (67), and the surfaces of the first guiding plate (66) and the second guiding plate (67) are both obliquely arranged.
9. The production facility of astragalus peptides according to claim 8, wherein the first guide plate (66) and the second guide plate (67) are inclined in opposite directions, and the first guide plate (66) and the second guide plate (67) are inclined at an angle of 75 °.
10. A production method of an astragalus peptide, applied to the production equipment of an astragalus peptide according to any one of claims 1 to 9, characterized by comprising the following steps:
s1, feeding astragalus extract to be subjected to enzymolysis into a reaction tank (1);
s2, adding momordica grosvenori protease and phytase for enzymolysis reaction into a reaction tank (1) after adding the astragalus extract;
s3, heating the interior of a reaction tank (1) added with the astragalus extract, the momordica grosvenori protease and the phytase to 55-58 ℃, and then stirring and hydrolyzing the mixed solution in the reaction tank for 2-3 hours;
s4, performing enzymolysis reaction;
s5, discharging the extracting solution obtained after enzymolysis.
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| CN116731854B (en) | 2023-11-03 |
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